FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2025, 608 aa 1>>>pF1KE2025 608 - 608 aa - 608 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4514+/-0.000896; mu= 14.8298+/- 0.054 mean_var=98.4197+/-20.184, 0's: 0 Z-trim(108.7): 34 B-trim: 4 in 2/51 Lambda= 0.129281 statistics sampled from 10474 (10498) to 10474 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.314), width: 16 Scan time: 1.640 The best scores are: opt bits E(33420) CCDS12250.1 CARM1 gene_id:10498|Hs109|chr19 ( 608) 4039 763.8 0 CCDS58200.1 PRMT8 gene_id:56341|Hs109|chr12 ( 385) 648 131.3 2.4e-30 CCDS8521.2 PRMT8 gene_id:56341|Hs109|chr12 ( 394) 648 131.3 2.4e-30 CCDS41360.2 PRMT6 gene_id:55170|Hs109|chr1 ( 375) 647 131.1 2.7e-30 CCDS42592.1 PRMT1 gene_id:3276|Hs109|chr19 ( 353) 641 129.9 5.5e-30 CCDS46145.1 PRMT1 gene_id:3276|Hs109|chr19 ( 371) 641 130.0 5.7e-30 CCDS44554.1 PRMT3 gene_id:10196|Hs109|chr11 ( 469) 642 130.2 6.1e-30 CCDS7853.1 PRMT3 gene_id:10196|Hs109|chr11 ( 531) 642 130.2 6.8e-30 CCDS13737.1 PRMT2 gene_id:3275|Hs109|chr21 ( 433) 625 127.0 5.1e-29 CCDS68230.1 PRMT2 gene_id:3275|Hs109|chr21 ( 289) 461 96.3 5.9e-20 CCDS74425.1 PRMT1 gene_id:3276|Hs109|chr19 ( 285) 419 88.5 1.3e-17 CCDS56220.1 PRMT2 gene_id:3275|Hs109|chr21 ( 331) 368 79.0 1.1e-14 CCDS68231.1 PRMT2 gene_id:3275|Hs109|chr21 ( 301) 367 78.8 1.2e-14 CCDS74806.1 PRMT2 gene_id:3275|Hs109|chr21 ( 228) 361 77.6 2e-14 CCDS56219.1 PRMT2 gene_id:3275|Hs109|chr21 ( 284) 362 77.9 2.1e-14 >>CCDS12250.1 CARM1 gene_id:10498|Hs109|chr19 (608 aa) initn: 4039 init1: 4039 opt: 4039 Z-score: 4073.7 bits: 763.8 E(33420): 0 Smith-Waterman score: 4039; 100.0% identity (100.0% similar) in 608 aa overlap (1-608:1-608) 10 20 30 40 50 60 pF1KE2 MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAAAAAAVGPGAGGAGSAVPGGAGPCATVSVFPGARLLTIGDANGEIQRHAEQQALRLEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RAGPDSAGIALYSHEDVCVFKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 YNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 KVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHLAPFTDE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 EAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRC 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTT 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 PSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSVGHNNLIPLAN 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TGIVNHTHSRMGSIMSTGIVQGSSGAQGSGGGSTSAHYAVNSQFTMGGPAISMASPMSIP 550 560 570 580 590 600 pF1KE2 TNTMHYGS :::::::: CCDS12 TNTMHYGS >>CCDS58200.1 PRMT8 gene_id:56341|Hs109|chr12 (385 aa) initn: 570 init1: 328 opt: 648 Z-score: 658.5 bits: 131.3 E(33420): 2.4e-30 Smith-Waterman score: 648; 33.5% identity (65.9% similar) in 352 aa overlap (112-460:31-371) 90 100 110 120 130 140 pF1KE2 CSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERT : : . . .: :. .... . CCDS58 MESLASDGFKLKEVSSVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPE- 10 20 30 40 50 150 160 170 180 190 200 pF1KE2 EESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFF : .: ::. :.... ...:..: ::: ::. .. .:. ::::.::::: :.::::.: CCDS58 EMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMF 60 70 80 90 100 110 210 220 230 240 250 260 pF1KE2 AAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMG ::.:::.:....: :......: ..:.:.: . :... :::::: :: :.::::::: :: CCDS58 AAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMG 120 130 140 150 160 170 270 280 290 300 310 pF1KE2 YMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH : :: : ::.. . :. :.:::.: ::: . .... . :.: ...: : ..: . . CCDS58 YCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQ--YKDF-KIHWW--ENVY 180 190 200 210 220 230 320 330 340 350 360 370 pF1KE2 GVDLSALRGAAVDEYFRQPVVDTFDIR-ILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHM : :.. .: .:. : :.:: : . .. . :.. .: .: . : ... CCDS58 GFDMTCIRDVAMKE----PLVDIVDPKQVVTNACLIKEVDIYTVKTEELS-FTSAFCLQI 240 250 260 270 280 380 390 400 410 420 430 pF1KE2 LHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTC .. ::.:. .:.. : . .:::: : ::: :. ... : .. :. . :: CCDS58 QRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTI 290 300 310 320 330 340 440 450 460 470 480 490 pF1KE2 LLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWN . : .. :.......: : CCDS58 SMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR 350 360 370 380 >>CCDS8521.2 PRMT8 gene_id:56341|Hs109|chr12 (394 aa) initn: 570 init1: 328 opt: 648 Z-score: 658.4 bits: 131.3 E(33420): 2.4e-30 Smith-Waterman score: 648; 33.5% identity (65.9% similar) in 352 aa overlap (112-460:40-380) 90 100 110 120 130 140 pF1KE2 CSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERT : : . . .: :. .... . CCDS85 LLLRRKMAENAAESTEVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPE- 10 20 30 40 50 60 150 160 170 180 190 200 pF1KE2 EESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFF : .: ::. :.... ...:..: ::: ::. .. .:. ::::.::::: :.::::.: CCDS85 EMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMF 70 80 90 100 110 120 210 220 230 240 250 260 pF1KE2 AAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEPMG ::.:::.:....: :......: ..:.:.: . :... :::::: :: :.::::::: :: CCDS85 AAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMG 130 140 150 160 170 180 270 280 290 300 310 pF1KE2 YMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH : :: : ::.. . :. :.:::.: ::: . .... . :.: ...: : ..: . . CCDS85 YCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQ--YKDF-KIHWW--ENVY 190 200 210 220 230 240 320 330 340 350 360 370 pF1KE2 GVDLSALRGAAVDEYFRQPVVDTFDIR-ILMAKSVKYTVNFLEAKEGDLHRIEIPFKFHM : :.. .: .:. : :.:: : . .. . :.. .: .: . : ... CCDS85 GFDMTCIRDVAMKE----PLVDIVDPKQVVTNACLIKEVDIYTVKTEELS-FTSAFCLQI 250 260 270 280 290 380 390 400 410 420 430 pF1KE2 LHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTC .. ::.:. .:.. : . .:::: : ::: :. ... : .. :. . :: CCDS85 QRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTI 300 310 320 330 340 350 440 450 460 470 480 490 pF1KE2 LLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWN . : .. :.......: : CCDS85 SMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR 360 370 380 390 >>CCDS41360.2 PRMT6 gene_id:55170|Hs109|chr1 (375 aa) initn: 558 init1: 436 opt: 647 Z-score: 657.7 bits: 131.1 E(33420): 2.7e-30 Smith-Waterman score: 647; 35.8% identity (65.6% similar) in 352 aa overlap (128-469:29-371) 100 110 120 130 140 150 pF1KE2 FIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLS : .::: .::.. :.. :. .: CCDS41 MSQPKKRKLESGGGGEGGEGTEEEDGAEREAALER---PRRTKRERDQLYYECYSDVS 10 20 30 40 50 160 170 180 190 200 210 pF1KE2 QQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEAST ...:. : ::: .:. .::.: . .. : ::::: :.::::.: ::::::..::::::. CCDS41 VHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIFCAQAGARRVYAVEASA 60 70 80 90 100 110 220 230 240 250 260 270 pF1KE2 MAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAK- . :.:. .:. :.: ::. :.:: :: : :::::: :.:: ::: :..: :: : :::. CCDS41 IWQQAREVVRFNGLEDRVHVLPGPVETVELPEQVDAIVSEWMGYGLLHESMLSSVLHART 120 130 140 150 160 170 280 290 300 310 320 330 pF1KE2 KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPSFH-GVDLSALRGAAVDEYF :.:: .: ..:. ... .::..:..: . .:: : . : :::.: :.: :. . CCDS41 KWLKEGGLLLPASAELFIAPISDQMLEW----RLGFWSQVKQHYGVDMSCLEGFATRCLM 180 190 200 210 220 230 340 350 360 370 380 pF1KE2 --RQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIP----FKFHMLHSGLVHGLAF . ::. .. . ..:. ... .. .. : ...: :. :. .::.:. CCDS41 GHSEIVVQGLSGEDVLARPQRFA-QLELSRAGLEQELEAGVGGRFRCSCYGSAPMHGFAI 240 250 260 270 280 290 390 400 410 420 430 440 pF1KE2 WFDVAFIG--SIMTVWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQS ::.:.: : : . :::.: .: ::: :. .. :. .. .:: :. .. . CCDS41 WFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDVSGEITLLPSRDNP 300 310 320 330 340 350 450 460 470 480 490 500 pF1KE2 YDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSS . .. . ..:.. . :. CCDS41 RRLRVLLRY-KVGDQEEKTKDFAMED 360 370 >>CCDS42592.1 PRMT1 gene_id:3276|Hs109|chr19 (353 aa) initn: 518 init1: 320 opt: 641 Z-score: 652.1 bits: 129.9 E(33420): 5.5e-30 Smith-Waterman score: 641; 35.9% identity (68.8% similar) in 320 aa overlap (144-460:30-339) 120 130 140 150 160 170 pF1KE2 PNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQ .: ::. :.... ...:..: ::: ::. CCDS42 MAAAEAANCIMEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYR 10 20 30 40 50 180 190 200 210 220 230 pF1KE2 RAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTD ....:. ::::.::::: :.::: .:::.:::::. ..: :.....: .::.:.: CCDS42 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDH 60 70 80 90 100 110 240 250 260 270 280 290 pF1KE2 RIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGD ...: :::::: :: :.::::::: ::: :: : ::.. :.:. :.: :.: .:: . CCDS42 VVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRAT 120 130 140 150 160 170 300 310 320 330 340 350 pF1KE2 VHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK .... . :.: : . : ..: . .: :.: .. .:. ..:.::. : . :... CCDS42 LYVTAIEDRQ-YKDY--KIHWW--ENVYGFDMSCIKDVAI----KEPLVDVVDPKQLVTN 180 190 200 210 220 230 360 370 380 390 400 410 pF1KE2 S-VKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTE . . :.. .: :: . :: ... .. ::.:. .:.. : . .::.: CCDS42 ACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPES 240 250 260 270 280 420 430 440 450 460 470 pF1KE2 PLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLK : ::: :. ... : .:.:. . :: . : ... :.... ..: : CCDS42 PYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTD 290 300 310 320 330 340 480 490 500 510 520 530 pF1KE2 NPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSV CCDS42 YRMR 350 >>CCDS46145.1 PRMT1 gene_id:3276|Hs109|chr19 (371 aa) initn: 518 init1: 320 opt: 641 Z-score: 651.7 bits: 130.0 E(33420): 5.7e-30 Smith-Waterman score: 641; 35.9% identity (68.8% similar) in 320 aa overlap (144-460:48-357) 120 130 140 150 160 170 pF1KE2 PNDFCSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQ .: ::. :.... ...:..: ::: ::. CCDS46 LANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYR 20 30 40 50 60 70 180 190 200 210 220 230 pF1KE2 RAILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTD ....:. ::::.::::: :.::: .:::.:::::. ..: :.....: .::.:.: CCDS46 NSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDH 80 90 100 110 120 130 240 250 260 270 280 290 pF1KE2 RIVVIPGKVEEVSLP-EQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGD ...: :::::: :: :.::::::: ::: :: : ::.. :.:. :.: :.: .:: . CCDS46 VVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRAT 140 150 160 170 180 190 300 310 320 330 340 350 pF1KE2 VHLAPFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK .... . :.: : . : ..: . .: :.: .. .:. ..:.::. : . :... CCDS46 LYVTAIEDRQ-YKDY--KIHWW--ENVYGFDMSCIKDVAI----KEPLVDVVDPKQLVTN 200 210 220 230 240 360 370 380 390 400 410 pF1KE2 S-VKYTVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTE . . :.. .: :: . :: ... .. ::.:. .:.. : . .::.: CCDS46 ACLIKEVDIYTVKVEDL-TFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPES 250 260 270 280 290 300 420 430 440 450 460 470 pF1KE2 PLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLK : ::: :. ... : .:.:. . :: . : ... :.... ..: : CCDS46 PYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTD 310 320 330 340 350 360 480 490 500 510 520 530 pF1KE2 NPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGSSV CCDS46 YRMR 370 >>CCDS44554.1 PRMT3 gene_id:10196|Hs109|chr11 (469 aa) initn: 595 init1: 328 opt: 642 Z-score: 651.2 bits: 130.2 E(33420): 6.1e-30 Smith-Waterman score: 642; 34.4% identity (67.0% similar) in 355 aa overlap (110-459:126-462) 80 90 100 110 120 130 pF1KE2 FKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSE ::: .:: .. .:: . : ::... CCDS44 VVEKLKHMEARALSAEAALARAREDLQKMKQFA--QDFVMHTDV-RTCSSST---SVIAD 100 110 120 130 140 140 150 160 170 180 190 pF1KE2 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS :. ..: ::. ::. . ...:..: .:: .:. : :: ::::.:::::::.:::: CCDS44 LQEDEDGV-YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS 150 160 170 180 190 200 200 210 220 230 240 250 pF1KE2 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEP .:::.:::.:. .:. : . .: ... :.: : :..: ::.::: :: :.::.:::: CCDS44 MFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEW 210 220 230 240 250 260 260 270 280 290 300 310 pF1KE2 MGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPS :::.:. : ::.: :.:: ::: .:...: : . :. .: . . . . :: . CCDS44 MGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHAD---RIAFW--DD 270 280 290 300 310 320 320 330 340 350 360 370 pF1KE2 FHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK--SVKYTVNFLEAKEGDLHRIEIPFK .: .: .. :.. : ::...: . :... ..:. .. .. .::. . : CCDS44 VYGFKMSCMKKAVIPE----AVVEVLDPKTLISEPCGIKH-IDCHTTSISDLE-FSSDFT 330 340 350 360 370 380 390 400 410 420 430 pF1KE2 FHMLHSGLVHGLAFWFDVAFIGSIMT-VWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTL ... .... ..: .::. : . . : .::.: ::: :. :...:. .:::..: CCDS44 LKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEAL 380 390 400 410 420 430 440 450 460 470 480 490 pF1KE2 SGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSE .: . ::.. ..... .... CCDS44 KGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ 440 450 460 >>CCDS7853.1 PRMT3 gene_id:10196|Hs109|chr11 (531 aa) initn: 571 init1: 328 opt: 642 Z-score: 650.4 bits: 130.2 E(33420): 6.8e-30 Smith-Waterman score: 642; 34.4% identity (67.0% similar) in 355 aa overlap (110-459:188-524) 80 90 100 110 120 130 pF1KE2 FKCSVSRETECSRVGKQSFIITLGCNSVLIQFATPNDFCSFYNILKTCRGHTLERSVFSE ::: .:: .. .:: . : ::... CCDS78 VVEKLKHMEARALSAEAALARAREDLQKMKQFA--QDFVMHTDV-RTCSSST---SVIAD 160 170 180 190 200 210 140 150 160 170 180 190 pF1KE2 RTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDFKDKIVLDVGCGSGILS :. ..: ::. ::. . ...:..: .:: .:. : :: ::::.:::::::.:::: CCDS78 LQEDEDGV-YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS 220 230 240 250 260 270 200 210 220 230 240 250 pF1KE2 FFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLP-EQVDIIISEP .:::.:::.:. .:. : . .: ... :.: : :..: ::.::: :: :.::.:::: CCDS78 MFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEW 280 290 300 310 320 330 260 270 280 290 300 310 pF1KE2 MGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQLYMEQFTKANFWYQPS :::.:. : ::.: :.:: ::: .:...: : . :. .: . . . . :: . CCDS78 MGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHAD---RIAFW--DD 340 350 360 370 380 320 330 340 350 360 370 pF1KE2 FHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAK--SVKYTVNFLEAKEGDLHRIEIPFK .: .: .. :.. : ::...: . :... ..:. .. .. .::. . : CCDS78 VYGFKMSCMKKAVIPE----AVVEVLDPKTLISEPCGIKH-IDCHTTSISDLE-FSSDFT 390 400 410 420 430 380 390 400 410 420 430 pF1KE2 FHMLHSGLVHGLAFWFDVAFIGSIMT-VWLSTAPTEPLTHWYQVRCLFQSPLFAKAGDTL ... .... ..: .::. : . . : .::.: ::: :. :...:. .:::..: CCDS78 LKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEAL 440 450 460 470 480 490 440 450 460 470 480 490 pF1KE2 SGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLDLKNPFFRYTGTTPSPPPGSHYTSPSE .: . ::.. ..... .... CCDS78 KGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ 500 510 520 530 >>CCDS13737.1 PRMT2 gene_id:3275|Hs109|chr21 (433 aa) initn: 434 init1: 225 opt: 625 Z-score: 634.6 bits: 127.0 E(33420): 5.1e-29 Smith-Waterman score: 625; 37.3% identity (66.2% similar) in 314 aa overlap (148-452:101-407) 120 130 140 150 160 170 pF1KE2 CSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAIL .:: :: :. . .:. : :: :. .:: CCDS13 ERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVIL 80 90 100 110 120 130 180 190 200 210 220 230 pF1KE2 QNHTDFKDKIVLDVGCGSGILSFFAAQ-AGARKIYAVEASTMAQHAEVLVKSNNLTDRIV ::. .. ::..::::::.::.:.: :. : : .:::::: ::::. :: .:...: :. CCDS13 QNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIIT 140 150 160 170 180 190 240 250 260 270 280 290 pF1KE2 VIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKK-YLKPSGNMFPTIGDVHLA : :::.: :::.::...:: :: :. : :.:: :.:. .:: .: ..::.. .::. CCDS13 VYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLV 200 210 220 230 240 250 300 310 320 330 340 350 pF1KE2 PFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKY : . .. : .:. :: . . .::::.. :: :.: .: . . .. : CCDS13 PCSADKDYR---SKVLFW--DNAYEFNLSALKSLAVKEFFSKPKYNHI-LKPEDCLSEPC 260 270 280 290 300 360 370 380 390 400 pF1KE2 TVNFLEAKE---GDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFI----GSIMTVWLSTAP :. :. . .::. .. ..: . ..: .::.. ::.: : :. : :::.: CCDS13 TILQLDMRTVQISDLETLRGELRFDIRKAGTLHGFTAWFSVHFQSLQEGQPPQV-LSTGP 310 320 330 340 350 360 410 420 430 440 450 460 pF1KE2 TEPLTHWYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQTGSKSSNLLD .: ::: :. ....:. ...::...:. .: : .:. CCDS13 FHPTTHWKQTLFMMDDPVPVHTGDVVTGSVVLQRNPVWRRHMSVALSWAVTSRQDPTSQK 370 380 390 400 410 420 470 480 490 500 510 520 pF1KE2 LKNPFFRYTGTTPSPPPGSHYTSPSENMWNTGSTYNLSSGMAVAGMPTAYDLSSVIASGS CCDS13 VGEKVFPIWR 430 >>CCDS68230.1 PRMT2 gene_id:3275|Hs109|chr21 (289 aa) initn: 430 init1: 206 opt: 461 Z-score: 471.9 bits: 96.3 E(33420): 5.9e-20 Smith-Waterman score: 461; 44.5% identity (71.4% similar) in 182 aa overlap (148-327:101-277) 120 130 140 150 160 170 pF1KE2 CSFYNILKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAIL .:: :: :. . .:. : :: :. .:: CCDS68 ERAGCCGYIPANHVGKHVDEYDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVIL 80 90 100 110 120 130 180 190 200 210 220 230 pF1KE2 QNHTDFKDKIVLDVGCGSGILSFFAAQ-AGARKIYAVEASTMAQHAEVLVKSNNLTDRIV ::. .. ::..::::::.::.:.: :. : : .:::::: ::::. :: .:...: :. CCDS68 QNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIIT 140 150 160 170 180 190 240 250 260 270 280 290 pF1KE2 VIPGKVEEVSLPEQVDIIISEPMGYMLFNERMLESYLHAKK-YLKPSGNMFPTIGDVHLA : :::.: :::.::...:: :: :. : :.:: :.:. .:: .: ..::.. .::. CCDS68 VYQQKVEDVVLPEKVDVLVSEWMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLV 200 210 220 230 240 250 300 310 320 330 340 350 pF1KE2 PFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKY : . .. : .:. :: . . .::::. CCDS68 PCSADKDYR---SKVLFW--DNAYEFNLSALKLEKKSSPSGDDS 260 270 280 360 370 380 390 400 410 pF1KE2 TVNFLEAKEGDLHRIEIPFKFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTHW 608 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Jul 16 16:06:48 2019 done: Tue Jul 16 16:06:48 2019 Total Scan time: 1.640 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]