Result of FASTA (omim) for pF1KE2202
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2202, 943 aa
  1>>>pF1KE2202 943 - 943 aa - 943 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.5807+/-0.000522; mu= 5.4046+/- 0.032
 mean_var=172.8157+/-35.655, 0's: 0 Z-trim(113.7): 60  B-trim: 571 in 2/48
 Lambda= 0.097562
 statistics sampled from 23090 (23120) to 23090 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.271), width:  16
 Scan time: 10.030

The best scores are:                                      opt bits E(85289)
NP_001803 (OMIM: 117141) centromere protein C [Hom ( 943) 6151 879.2       0
XP_006714127 (OMIM: 117141) PREDICTED: centromere  ( 935) 6070 867.8       0
XP_011529844 (OMIM: 117141) PREDICTED: centromere  ( 772) 4964 712.1 2.7e-204


>>NP_001803 (OMIM: 117141) centromere protein C [Homo sa  (943 aa)
 initn: 6151 init1: 6151 opt: 6151  Z-score: 4690.4  bits: 879.2 E(85289):    0
Smith-Waterman score: 6151; 100.0% identity (100.0% similar) in 943 aa overlap (1-943:1-943)

               10        20        30        40        50        60
pF1KE2 MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 RKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDL
              790       800       810       820       830       840

              850       860       870       880       890       900
pF1KE2 VRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLL
              850       860       870       880       890       900

              910       920       930       940   
pF1KE2 CTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR
       :::::::::::::::::::::::::::::::::::::::::::
NP_001 CTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR
              910       920       930       940   

>>XP_006714127 (OMIM: 117141) PREDICTED: centromere prot  (935 aa)
 initn: 5241 init1: 5241 opt: 6070  Z-score: 4628.8  bits: 867.8 E(85289):    0
Smith-Waterman score: 6070; 99.0% identity (99.2% similar) in 943 aa overlap (1-943:1-935)

               10        20        30        40        50        60
pF1KE2 MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSK
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KE2 RKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDL
       ::::::::::::::::::::::::::.        :::::::::::::::::::::::::
XP_006 RKAKENIGKVNKKSNKKRICLDNDERS--------IPLGDPLQPTRVKDPETREIILMDL
              790       800               810       820       830  

              850       860       870       880       890       900
pF1KE2 VRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VRPQDTYQFFVKHGELKVYKTLDTPFFSTGKLILGPQEEKGKQHVGQDILVFYVNFGDLL
            840       850       860       870       880       890  

              910       920       930       940   
pF1KE2 CTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR
       :::::::::::::::::::::::::::::::::::::::::::
XP_006 CTLHETPYILSTGDSFYVPSGNYYNIKNLRNEESVLLFTQIKR
            900       910       920       930     

>>XP_011529844 (OMIM: 117141) PREDICTED: centromere prot  (772 aa)
 initn: 4963 init1: 4963 opt: 4964  Z-score: 3788.7  bits: 712.1 E(85289): 2.7e-204
Smith-Waterman score: 4964; 99.0% identity (99.4% similar) in 772 aa overlap (1-772:1-772)

               10        20        30        40        50        60
pF1KE2 MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAASGLDHLKNGYRRRFCRPSRARDINTEQGQNVLEILQDCFEEKSLANDFSTNSTKSVP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSTRKIKDTCIQSPSKECQKSHPKSVPVSSKKKEASLQFVVEPSEATNRSVQAHEVHQKI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LATDVSSKNTPDSKKISSRNINDHHSEADEEFYLSVGSPSVLLDAKTSVSQNVIPSSAQK
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RETYTFENSVNMLPSSTEVSVKTKKRLNFDDKVMLKKIEIDNKVSDEEDKTSEGQERKPS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSSQNRIRDSEYEIQRQAKKSFSTLFLETVKRKSESSPIVRHAATAPPHSCPPDDTKLIE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEFIIDESDQSFASRSWITIPRKAGSLKQRTISPAESTALLQGRKSREKHHNILPKTLAN
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKHSHKPHPVETSQPSDKTVLDTSYALIGETVNNYRSTKYEMYSKNAEKPSRSKRTIKQK
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QRRKFMAKPAEEQLDVGQSKDENIHTSHITQDEFQRNSDRNMEEHEEMGNDCVSKKQMPP
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KE2 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGSKKSSTRKDKEESKKKRFSSESKNKLVPEEVTSTVTKSRRISRRPSDWWVVKSEESPV
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KE2 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSNSSVRNELPMHHNSSRKSTKKTNQSSKNIRKKTIPLKRQKTATKGNQRVQKFLNAEGS
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KE2 GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGIVGHDEISRCSLSEPLESDEADLAKKKNLDCSRSTRSSKNEDNIMTAQNVPLKPQTSG
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KE2 YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTCNIPTESNLDSGEHKTSVLEESGPSRLNNNYLMSGKNDVDDEEVHGSSDDSKQSKVIP
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KE2 KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSGGFVISGVLSPDTISSK
       :::::::::::::::::::::::::::::::::::::::::::.    : ..        
XP_011 KNRIHHKLVLPSNTPNVRRTKRTRLKPLEYWRGERIDYQGRPSAECCYSCII        
              730       740       750       760       770          

              790       800       810       820       830       840
pF1KE2 RKAKENIGKVNKKSNKKRICLDNDERKTNLMVNLGIPLGDPLQPTRVKDPETREIILMDL




943 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 00:32:29 2016 done: Tue Nov  8 00:32:30 2016
 Total Scan time: 10.030 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]
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