FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2300, 857 aa 1>>>pF1KE2300 857 - 857 aa - 857 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.9726+/-0.00134; mu= -12.8422+/- 0.077 mean_var=406.6651+/-95.220, 0's: 0 Z-trim(106.3): 288 B-trim: 0 in 0/51 Lambda= 0.063600 statistics sampled from 8601 (8888) to 8601 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.273), width: 16 Scan time: 4.400 The best scores are: opt bits E(32554) CCDS4993.1 TTK gene_id:7272|Hs108|chr6 ( 857) 5664 535.7 1.4e-151 CCDS55040.1 TTK gene_id:7272|Hs108|chr6 ( 856) 5645 533.9 4.5e-151 >>CCDS4993.1 TTK gene_id:7272|Hs108|chr6 (857 aa) initn: 5664 init1: 5664 opt: 5664 Z-score: 2835.1 bits: 535.7 E(32554): 1.4e-151 Smith-Waterman score: 5664; 100.0% identity (100.0% similar) in 857 aa overlap (1-857:1-857) 10 20 30 40 50 60 pF1KE2 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS49 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE 790 800 810 820 830 840 850 pF1KE2 SHNSSSSKTFEKKRGKK ::::::::::::::::: CCDS49 SHNSSSSKTFEKKRGKK 850 >>CCDS55040.1 TTK gene_id:7272|Hs108|chr6 (856 aa) initn: 2936 init1: 2936 opt: 5645 Z-score: 2825.7 bits: 533.9 E(32554): 4.5e-151 Smith-Waterman score: 5645; 99.9% identity (99.9% similar) in 857 aa overlap (1-857:1-856) 10 20 30 40 50 60 pF1KE2 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTE- 370 380 390 400 410 430 440 450 460 470 480 pF1KE2 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE2 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE2 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM 540 550 560 570 580 590 610 620 630 640 650 660 pF1KE2 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML 600 610 620 630 640 650 670 680 690 700 710 720 pF1KE2 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL 660 670 680 690 700 710 730 740 750 760 770 780 pF1KE2 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI 720 730 740 750 760 770 790 800 810 820 830 840 pF1KE2 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE 780 790 800 810 820 830 850 pF1KE2 SHNSSSSKTFEKKRGKK ::::::::::::::::: CCDS55 SHNSSSSKTFEKKRGKK 840 850 857 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 03:01:21 2016 done: Mon Nov 7 03:01:22 2016 Total Scan time: 4.400 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]