FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2300, 857 aa 1>>>pF1KE2300 857 - 857 aa - 857 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.2749+/-0.000644; mu= -12.0354+/- 0.039 mean_var=774.7024+/-176.859, 0's: 0 Z-trim(114.4): 399 B-trim: 0 in 0/56 Lambda= 0.046079 statistics sampled from 23847 (24222) to 23847 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.284), width: 16 Scan time: 12.710 The best scores are: opt bits E(85289) NP_003309 (OMIM: 604092) dual specificity protein ( 857) 5664 394.0 1.6e-108 XP_011534401 (OMIM: 604092) PREDICTED: dual specif ( 857) 5664 394.0 1.6e-108 XP_011534402 (OMIM: 604092) PREDICTED: dual specif ( 856) 5645 392.7 3.8e-108 NP_001160163 (OMIM: 604092) dual specificity prote ( 856) 5645 392.7 3.8e-108 XP_016866731 (OMIM: 604092) PREDICTED: dual specif ( 802) 5327 371.5 8.5e-102 >>NP_003309 (OMIM: 604092) dual specificity protein kina (857 aa) initn: 5664 init1: 5664 opt: 5664 Z-score: 2069.3 bits: 394.0 E(85289): 1.6e-108 Smith-Waterman score: 5664; 100.0% identity (100.0% similar) in 857 aa overlap (1-857:1-857) 10 20 30 40 50 60 pF1KE2 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE 790 800 810 820 830 840 850 pF1KE2 SHNSSSSKTFEKKRGKK ::::::::::::::::: NP_003 SHNSSSSKTFEKKRGKK 850 >>XP_011534401 (OMIM: 604092) PREDICTED: dual specificit (857 aa) initn: 5664 init1: 5664 opt: 5664 Z-score: 2069.3 bits: 394.0 E(85289): 1.6e-108 Smith-Waterman score: 5664; 100.0% identity (100.0% similar) in 857 aa overlap (1-857:1-857) 10 20 30 40 50 60 pF1KE2 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE 790 800 810 820 830 840 850 pF1KE2 SHNSSSSKTFEKKRGKK ::::::::::::::::: XP_011 SHNSSSSKTFEKKRGKK 850 >>XP_011534402 (OMIM: 604092) PREDICTED: dual specificit (856 aa) initn: 2936 init1: 2936 opt: 5645 Z-score: 2062.5 bits: 392.7 E(85289): 3.8e-108 Smith-Waterman score: 5645; 99.9% identity (99.9% similar) in 857 aa overlap (1-857:1-856) 10 20 30 40 50 60 pF1KE2 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTE- 370 380 390 400 410 430 440 450 460 470 480 pF1KE2 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE2 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE2 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM 540 550 560 570 580 590 610 620 630 640 650 660 pF1KE2 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML 600 610 620 630 640 650 670 680 690 700 710 720 pF1KE2 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL 660 670 680 690 700 710 730 740 750 760 770 780 pF1KE2 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI 720 730 740 750 760 770 790 800 810 820 830 840 pF1KE2 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE 780 790 800 810 820 830 850 pF1KE2 SHNSSSSKTFEKKRGKK ::::::::::::::::: XP_011 SHNSSSSKTFEKKRGKK 840 850 >>NP_001160163 (OMIM: 604092) dual specificity protein k (856 aa) initn: 2936 init1: 2936 opt: 5645 Z-score: 2062.5 bits: 392.7 E(85289): 3.8e-108 Smith-Waterman score: 5645; 99.9% identity (99.9% similar) in 857 aa overlap (1-857:1-856) 10 20 30 40 50 60 pF1KE2 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESEDLSGRELTIDSIMNKVRDIKNKFKNEDLTDELSLNKISADTTDNSGTVNQIMMMAN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPEDWLSLLLKLEKNSVPLSDALLNKLIGRYSQAIEALPPDKYGQNESFARIQVRFAELK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIQEPDDARDYFQMARANCKKFAFVHISFAQFELSQGNVKKSKQLLQKAVERGAVPLEML 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIALRNLNLQKKQLLSEEEKKNLSASTVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYGENMPPQDAEIGYRNSLRQTNKTKQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSRSECRDLVVPGSKPSGNDSCELRNLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTEQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESSLLAKLEETKEYQEPEVPESNQKQWQSKRKSECINQNPAASSNHWQIPELARKVNTE- 370 380 390 400 410 430 440 450 460 470 480 pF1KE2 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHTTFEQPVFSVSKQSPPISTSKWFDPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE2 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSTPYGQPACFQQQQHQILATPLQNLQVLASSSANECISVKGRIYSILKQIGSGGSSKVF 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE2 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYM 540 550 560 570 580 590 610 620 630 640 650 660 pF1KE2 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VMECGNIDLNSWLKKKKSIDPWERKSYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGML 600 610 620 630 640 650 670 680 690 700 710 720 pF1KE2 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLIDFGIANQMQPDTTSVVKDSQVGTVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSL 660 670 680 690 700 710 730 740 750 760 770 780 pF1KE2 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRI 720 730 740 750 760 770 790 800 810 820 830 840 pF1KE2 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIPELLAHPYVQIQTHPVNQMAKGTTEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGE 780 790 800 810 820 830 850 pF1KE2 SHNSSSSKTFEKKRGKK ::::::::::::::::: NP_001 SHNSSSSKTFEKKRGKK 840 850 >>XP_016866731 (OMIM: 604092) PREDICTED: dual specificit (802 aa) initn: 5327 init1: 5327 opt: 5327 Z-score: 1948.5 bits: 371.5 E(85289): 8.5e-102 Smith-Waterman score: 5327; 100.0% identity (100.0% similar) in 802 aa overlap (56-857:1-802) 30 40 50 60 70 80 pF1KE2 KFKNEDLTDELSLNKISADTTDNSGTVNQIMMMANNPEDWLSLLLKLEKNSVPLSDALLN :::::::::::::::::::::::::::::: XP_016 MMMANNPEDWLSLLLKLEKNSVPLSDALLN 10 20 30 90 100 110 120 130 140 pF1KE2 KLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLIGRYSQAIEALPPDKYGQNESFARIQVRFAELKAIQEPDDARDYFQMARANCKKFAFV 40 50 60 70 80 90 150 160 170 180 190 200 pF1KE2 HISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HISFAQFELSQGNVKKSKQLLQKAVERGAVPLEMLEIALRNLNLQKKQLLSEEEKKNLSA 100 110 120 130 140 150 210 220 230 240 250 260 pF1KE2 STVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGENMPPQDAEIGYRNSLRQTNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STVLTAQESFSGSLGHLQNRNNSCDSRGQTTKARFLYGENMPPQDAEIGYRNSLRQTNKT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KE2 KQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQTSRSECRDLVVPGSKPSGNDSCELR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQSCPFGRVPVNLLNSPDCDVKTDDSVVPCFMKRQTSRSECRDLVVPGSKPSGNDSCELR 220 230 240 250 260 270 330 340 350 360 370 380 pF1KE2 NLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQEPEVPESNQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLKSVQNSHFKEPLVSDEKSSELIITDSITLKNKTESSLLAKLEETKEYQEPEVPESNQK 280 290 300 310 320 330 390 400 410 420 430 440 pF1KE2 QWQSKRKSECINQNPAASSNHWQIPELARKVNTEQKHTTFEQPVFSVSKQSPPISTSKWF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QWQSKRKSECINQNPAASSNHWQIPELARKVNTEQKHTTFEQPVFSVSKQSPPISTSKWF 340 350 360 370 380 390 450 460 470 480 490 500 pF1KE2 DPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPKSICKTPSSNTLDDYMSCFRTPVVKNDFPPACQLSTPYGQPACFQQQQHQILATPLQN 400 410 420 430 440 450 510 520 530 540 550 560 pF1KE2 LQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQVLASSSANECISVKGRIYSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTL 460 470 480 490 500 510 570 580 590 600 610 620 pF1KE2 DSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSYRNEIAYLNKLQQHSDKIIRLYDYEITDQYIYMVMECGNIDLNSWLKKKKSIDPWERK 520 530 540 550 560 570 630 640 650 660 670 680 pF1KE2 SYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYWKNMLEAVHTIHQHGIVHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSVVKDSQVG 580 590 600 610 620 630 690 700 710 720 730 740 pF1KE2 TVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVNYMPPEAIKDMSSSRENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLH 640 650 660 670 680 690 750 760 770 780 790 800 pF1KE2 AIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AIIDPNHEIEFPDIPEKDLQDVLKCCLKRDPKQRISIPELLAHPYVQIQTHPVNQMAKGT 700 710 720 730 740 750 810 820 830 840 850 pF1KE2 TEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGKK :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TEEMKYVLGQLVGLNSPNSILKAAKTLYEHYSGGESHNSSSSKTFEKKRGKK 760 770 780 790 800 857 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 03:01:22 2016 done: Mon Nov 7 03:01:24 2016 Total Scan time: 12.710 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]