FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2307, 302 aa 1>>>pF1KE2307 302 - 302 aa - 302 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.7402+/-0.000987; mu= 9.0880+/- 0.059 mean_var=143.7478+/-40.724, 0's: 0 Z-trim(106.7): 110 B-trim: 489 in 1/48 Lambda= 0.106973 statistics sampled from 9034 (9158) to 9034 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.641), E-opt: 0.2 (0.281), width: 16 Scan time: 2.560 The best scores are: opt bits E(32554) CCDS45841.1 HRH4 gene_id:59340|Hs108|chr18 ( 302) 2002 320.8 8.2e-88 CCDS11887.1 HRH4 gene_id:59340|Hs108|chr18 ( 390) 1612 260.7 1.3e-69 CCDS13493.1 HRH3 gene_id:11255|Hs108|chr20 ( 445) 351 66.1 5.4e-11 >>CCDS45841.1 HRH4 gene_id:59340|Hs108|chr18 (302 aa) initn: 2002 init1: 2002 opt: 2002 Z-score: 1690.0 bits: 320.8 E(32554): 8.2e-88 Smith-Waterman score: 2002; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE2 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 DFFVVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DFFVVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 SNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 YSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSV 250 260 270 280 290 300 pF1KE2 SS :: CCDS45 SS >>CCDS11887.1 HRH4 gene_id:59340|Hs108|chr18 (390 aa) initn: 1612 init1: 1612 opt: 1612 Z-score: 1363.3 bits: 260.7 E(32554): 1.3e-69 Smith-Waterman score: 1612; 97.2% identity (99.2% similar) in 246 aa overlap (57-302:145-390) 30 40 50 60 70 80 pF1KE2 FAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVVSESWKDEGSECEPGFFSEWYI :. . ...:::::::::::::::::::::: CCDS11 SVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYI 120 130 140 150 160 170 90 100 110 120 130 140 pF1KE2 LAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSS 180 190 200 210 220 230 150 160 170 180 190 200 pF1KE2 RRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVE 240 250 260 270 280 290 210 220 230 240 250 260 pF1KE2 LLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVN 300 310 320 330 340 350 270 280 290 300 pF1KE2 PLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS :::::::::::::::::::::::::::::::::::: CCDS11 PLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS 360 370 380 390 >-- initn: 413 init1: 392 opt: 393 Z-score: 346.6 bits: 72.6 E(32554): 5.5e-13 Smith-Waterman score: 393; 56.7% identity (72.4% similar) in 134 aa overlap (1-131:1-132) 10 20 30 40 50 60 pF1KE2 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAIS 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 DFFV--VSESWKDEGSECEPGFFSEWYILAITS-FLEFVIPVILVAYFNMNIYWSLWKRD :::: .: . : : .: .. .:. .: . : .. .... : :. . CCDS11 DFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSV--SN 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 HLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRT .: .: :. . CCDS11 AVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAIT 120 130 140 150 160 170 >>CCDS13493.1 HRH3 gene_id:11255|Hs108|chr20 (445 aa) initn: 614 init1: 196 opt: 351 Z-score: 310.8 bits: 66.1 E(32554): 5.4e-11 Smith-Waterman score: 393; 32.1% identity (54.7% similar) in 265 aa overlap (72-294:185-439) 50 60 70 80 90 100 pF1KE2 VDKNLRHRSSYFFLNLAISDFFVVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVIL :: .: :: .::.: .: ::: : . CCDS13 KMLLVWVLAFLLYGPAILSWEYLSGGSSIPEG-HCYAEFFYNWYFLITASTLEFFTPFLS 160 170 180 190 200 210 110 120 pF1KE2 VAYFNMNIY------------------------------------WSLWKRDHLSRCQSH :..::..:: :. :.. : : CCDS13 VTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLH 220 230 240 250 260 270 130 140 150 160 170 180 pF1KE2 P---GLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSN : .::... :.. : .. :... : .: :. .: :: .:. . .: CCDS13 RYGVGEAAVGAEA-GEATLGGGGGGGSVASPTSSSGS-SSRGTERPRSLKRGSKPSASSA 280 290 300 310 320 330 190 200 210 220 230 240 pF1KE2 TIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYS .. ..: ::: . :: .: : :..:::::.....:..:::::.:. :. . CCDS13 SLEKRMKMVSQS----FTQR--FRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACH 340 350 360 370 380 250 260 270 280 290 pF1KE2 SATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKK---QPLPSQHSRS . : . ::. .::: : :: :::.::::::. :..:: :..: .: :: : CCDS13 GHCVP-DYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCW 390 400 410 420 430 440 300 pF1KE2 VSS CCDS13 K 302 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 13:42:59 2016 done: Sun Nov 6 13:42:59 2016 Total Scan time: 2.560 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]