FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2310, 1308 aa 1>>>pF1KE2310 1308 - 1308 aa - 1308 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 13.3587+/-0.000633; mu= -16.9413+/- 0.038 mean_var=802.8742+/-178.733, 0's: 0 Z-trim(116.3): 961 B-trim: 1497 in 1/57 Lambda= 0.045264 statistics sampled from 26075 (27335) to 26075 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.32), width: 16 Scan time: 16.230 The best scores are: opt bits E(85289) NP_005226 (OMIM: 600543,615515) receptor tyrosine- (1308) 9147 615.3 8.5e-175 XP_016859067 (OMIM: 600543,615515) PREDICTED: rece (1334) 7914 534.8 1.5e-150 NP_001036064 (OMIM: 600543,615515) receptor tyrosi (1292) 7348 497.9 1.9e-139 XP_016859070 (OMIM: 600543,615515) PREDICTED: rece (1318) 6115 417.4 3.4e-115 XP_016859068 (OMIM: 600543,615515) PREDICTED: rece (1333) 4793 331.0 3.3e-89 XP_016859066 (OMIM: 600543,615515) PREDICTED: rece (1349) 4753 328.4 2.1e-88 XP_006712427 (OMIM: 600543,615515) PREDICTED: rece (1323) 4752 328.3 2.1e-88 XP_016859071 (OMIM: 600543,615515) PREDICTED: rece (1116) 4748 328.0 2.3e-88 XP_016859069 (OMIM: 600543,615515) PREDICTED: rece (1324) 4559 315.7 1.3e-84 XP_005246434 (OMIM: 600543,615515) PREDICTED: rece (1282) 4503 312.1 1.6e-83 XP_005246433 (OMIM: 600543,615515) PREDICTED: rece (1298) 4503 312.1 1.6e-83 NP_004439 (OMIM: 137800,164870,211980,613659) rece (1255) 3812 266.9 6.2e-70 NP_001276865 (OMIM: 137800,164870,211980,613659) r (1240) 3808 266.7 7.4e-70 NP_001276866 (OMIM: 137800,164870,211980,613659) r (1055) 3798 265.9 1e-69 NP_001005862 (OMIM: 137800,164870,211980,613659) r (1225) 3776 264.6 3.1e-69 NP_001973 (OMIM: 190151,607598) receptor tyrosine- (1342) 3601 253.2 9e-66 NP_005219 (OMIM: 131550,211980,616069) epidermal g (1210) 3166 224.7 3e-57 NP_958439 (OMIM: 131550,211980,616069) epidermal g ( 628) 2194 160.9 2.6e-38 NP_958441 (OMIM: 131550,211980,616069) epidermal g ( 705) 2194 160.9 2.8e-38 NP_001276867 (OMIM: 137800,164870,211980,613659) r ( 603) 1655 125.7 1e-27 NP_958440 (OMIM: 131550,211980,616069) epidermal g ( 405) 1353 105.7 6.8e-22 XP_011542744 (OMIM: 601212) PREDICTED: protein-tyr ( 996) 767 68.0 3.9e-10 XP_016868704 (OMIM: 601212) PREDICTED: protein-tyr ( 996) 767 68.0 3.9e-10 XP_011542743 (OMIM: 601212) PREDICTED: protein-tyr (1009) 767 68.0 3.9e-10 NP_775266 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 767 68.0 3.9e-10 XP_005273504 (OMIM: 601212) PREDICTED: protein-tyr (1009) 767 68.0 3.9e-10 XP_016868703 (OMIM: 601212) PREDICTED: protein-tyr (1009) 767 68.0 3.9e-10 NP_004094 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 767 68.0 3.9e-10 NP_775268 (OMIM: 601212) protein-tyrosine kinase 2 (1009) 767 68.0 3.9e-10 XP_016869175 (OMIM: 600758) PREDICTED: focal adhes ( 942) 765 67.8 4.1e-10 XP_016869174 (OMIM: 600758) PREDICTED: focal adhes ( 948) 765 67.8 4.1e-10 XP_016869171 (OMIM: 600758) PREDICTED: focal adhes ( 976) 765 67.8 4.2e-10 NP_001186578 (OMIM: 600758) focal adhesion kinase (1065) 766 67.9 4.2e-10 XP_016869161 (OMIM: 600758) PREDICTED: focal adhes (1055) 765 67.9 4.4e-10 XP_016869160 (OMIM: 600758) PREDICTED: focal adhes (1055) 765 67.9 4.4e-10 XP_016869154 (OMIM: 600758) PREDICTED: focal adhes (1061) 765 67.9 4.4e-10 XP_016869153 (OMIM: 600758) PREDICTED: focal adhes (1061) 765 67.9 4.4e-10 XP_016869147 (OMIM: 600758) PREDICTED: focal adhes (1089) 765 67.9 4.5e-10 XP_016869146 (OMIM: 600758) PREDICTED: focal adhes (1099) 765 67.9 4.5e-10 XP_016869179 (OMIM: 600758) PREDICTED: focal adhes ( 913) 758 67.3 5.5e-10 XP_016869177 (OMIM: 600758) PREDICTED: focal adhes ( 919) 758 67.3 5.5e-10 XP_016869178 (OMIM: 600758) PREDICTED: focal adhes ( 919) 758 67.3 5.5e-10 XP_016869173 (OMIM: 600758) PREDICTED: focal adhes ( 949) 758 67.3 5.7e-10 NP_001303271 (OMIM: 600758) focal adhesion kinase ( 955) 758 67.3 5.7e-10 XP_016869172 (OMIM: 600758) PREDICTED: focal adhes ( 955) 758 67.3 5.7e-10 XP_006716672 (OMIM: 600758) PREDICTED: focal adhes ( 983) 758 67.4 5.8e-10 XP_006716673 (OMIM: 600758) PREDICTED: focal adhes ( 983) 758 67.4 5.8e-10 XP_005251070 (OMIM: 600758) PREDICTED: focal adhes ( 983) 758 67.4 5.8e-10 XP_016869169 (OMIM: 600758) PREDICTED: focal adhes ( 995) 758 67.4 5.8e-10 XP_016869166 (OMIM: 600758) PREDICTED: focal adhes (1032) 758 67.4 6e-10 >>NP_005226 (OMIM: 600543,615515) receptor tyrosine-prot (1308 aa) initn: 9147 init1: 9147 opt: 9147 Z-score: 3259.2 bits: 615.3 E(85289): 8.5e-175 Smith-Waterman score: 9147; 100.0% identity (100.0% similar) in 1308 aa overlap (1-1308:1-1308) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 NSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 YRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 YRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 EYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 pF1KE2 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV :::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV 1270 1280 1290 1300 >>XP_016859067 (OMIM: 600543,615515) PREDICTED: receptor (1334 aa) initn: 9133 init1: 7914 opt: 7914 Z-score: 2823.9 bits: 534.8 E(85289): 1.5e-150 Smith-Waterman score: 9085; 98.1% identity (98.1% similar) in 1334 aa overlap (1-1308:1-1334) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 pF1KE2 NGSSGC--------------------------GRCHKSCTGRCWGPTENHCQTLTRTVCA :::::: :::::::::::::::::::::::::::: XP_016 NGSSGCLAHQDTEKNNPQLLQSLQPFSLITPGGRCHKSCTGRCWGPTENHCQTLTRTVCA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE2 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE2 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE2 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE2 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE2 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE2 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP 550 560 570 580 590 600 580 590 600 610 620 630 pF1KE2 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCI 610 620 630 640 650 660 640 650 660 670 680 690 pF1KE2 YYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETEL 670 680 690 700 710 720 700 710 720 730 740 750 pF1KE2 VEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILN 730 740 750 760 770 780 760 770 780 790 800 810 pF1KE2 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDN 790 800 810 820 830 840 820 830 840 850 860 870 pF1KE2 IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKE 850 860 870 880 890 900 880 890 900 910 920 930 pF1KE2 YNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLE 910 920 930 940 950 960 940 950 960 970 980 990 pF1KE2 KGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMK 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KE2 LPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPP 1030 1040 1050 1060 1070 1080 1060 1070 1080 1090 1100 1110 pF1KE2 AYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKP 1090 1100 1110 1120 1130 1140 1120 1130 1140 1150 1160 1170 pF1KE2 VAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSR 1150 1160 1170 1180 1190 1200 1180 1190 1200 1210 1220 1230 pF1KE2 RKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAK 1210 1220 1230 1240 1250 1260 1240 1250 1260 1270 1280 1290 pF1KE2 KAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGT 1270 1280 1290 1300 1310 1320 1300 pF1KE2 VLPPPPYRHRNTVV :::::::::::::: XP_016 VLPPPPYRHRNTVV 1330 >>NP_001036064 (OMIM: 600543,615515) receptor tyrosine-p (1292 aa) initn: 7328 init1: 7328 opt: 7348 Z-score: 2624.3 bits: 497.9 E(85289): 1.9e-139 Smith-Waterman score: 8988; 98.8% identity (98.8% similar) in 1308 aa overlap (1-1308:1-1292) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 NSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVP ::::::::::::::::::::::::: ::::::::::::::::::: NP_001 EYLVPQAFNIPPPIYTSRARIDSNR----------------NQFVYRDGGFAAEQGVSVP 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KE2 YRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERS 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KE2 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KE2 EYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 pF1KE2 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV 1250 1260 1270 1280 1290 >>XP_016859070 (OMIM: 600543,615515) PREDICTED: receptor (1318 aa) initn: 7314 init1: 6095 opt: 6115 Z-score: 2189.1 bits: 417.4 E(85289): 3.4e-115 Smith-Waterman score: 8926; 96.9% identity (96.9% similar) in 1334 aa overlap (1-1308:1-1318) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 pF1KE2 NGSSGC--------------------------GRCHKSCTGRCWGPTENHCQTLTRTVCA :::::: :::::::::::::::::::::::::::: XP_016 NGSSGCLAHQDTEKNNPQLLQSLQPFSLITPGGRCHKSCTGRCWGPTENHCQTLTRTVCA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE2 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE2 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE2 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE2 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE2 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE2 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP 550 560 570 580 590 600 580 590 600 610 620 630 pF1KE2 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCI 610 620 630 640 650 660 640 650 660 670 680 690 pF1KE2 YYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETEL 670 680 690 700 710 720 700 710 720 730 740 750 pF1KE2 VEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILN 730 740 750 760 770 780 760 770 780 790 800 810 pF1KE2 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDN 790 800 810 820 830 840 820 830 840 850 860 870 pF1KE2 IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKE 850 860 870 880 890 900 880 890 900 910 920 930 pF1KE2 YNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLE 910 920 930 940 950 960 940 950 960 970 980 990 pF1KE2 KGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMK 970 980 990 1000 1010 1020 1000 1010 1020 1030 1040 1050 pF1KE2 LPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPP ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNR--------- 1030 1040 1050 1060 1070 1060 1070 1080 1090 1100 1110 pF1KE2 AYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKP ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 -------NQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKP 1080 1090 1100 1110 1120 1120 1130 1140 1150 1160 1170 pF1KE2 VAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSR 1130 1140 1150 1160 1170 1180 1180 1190 1200 1210 1220 1230 pF1KE2 RKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAK 1190 1200 1210 1220 1230 1240 1240 1250 1260 1270 1280 1290 pF1KE2 KAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGT 1250 1260 1270 1280 1290 1300 1300 pF1KE2 VLPPPPYRHRNTVV :::::::::::::: XP_016 VLPPPPYRHRNTVV 1310 >>XP_016859068 (OMIM: 600543,615515) PREDICTED: receptor (1333 aa) initn: 6180 init1: 3270 opt: 4793 Z-score: 1722.5 bits: 331.0 E(85289): 3.3e-89 Smith-Waterman score: 8886; 95.8% identity (95.8% similar) in 1349 aa overlap (1-1308:1-1333) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 pF1KE2 NGSSGC--------------------------GRCHKSCTGRCWGPTENHCQTLTRTVCA :::::: :::::::::::::::::::::::::::: XP_016 NGSSGCLAHQDTEKNNPQLLQSLQPFSLITPGGRCHKSCTGRCWGPTENHCQTLTRTVCA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE2 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE2 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE2 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE2 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE2 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE2 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP 550 560 570 580 590 600 580 590 600 610 620 pF1KE2 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGC--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCIGSSIEDCI 610 620 630 640 650 660 630 640 650 660 670 pF1KE2 ------NGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMDRCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKS 670 680 690 700 710 720 680 690 700 710 720 730 pF1KE2 IKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVP 730 740 750 760 770 780 740 750 760 770 780 790 pF1KE2 EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLM 790 800 810 820 830 840 800 810 820 830 840 850 pF1KE2 PHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKI 850 860 870 880 890 900 860 870 880 890 900 910 pF1KE2 TDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGK 910 920 930 940 950 960 920 930 940 950 960 970 pF1KE2 PYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMAR 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KE2 DPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRA 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KE2 RIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATA :::::: :::::::::::::::::::::::::::::::::::::: XP_016 RIDSNR----------------NQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATA 1090 1100 1110 1120 1100 1110 1120 1130 1140 1150 pF1KE2 EIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPK 1130 1140 1150 1160 1170 1180 1160 1170 1180 1190 1200 1210 pF1KE2 QEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKA 1190 1200 1210 1220 1230 1240 1220 1230 1240 1250 1260 1270 pF1KE2 EYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVA 1250 1260 1270 1280 1290 1300 1280 1290 1300 pF1KE2 ENPEYLSEFSLKPGTVLPPPPYRHRNTVV ::::::::::::::::::::::::::::: XP_016 ENPEYLSEFSLKPGTVLPPPPYRHRNTVV 1310 1320 1330 >>XP_016859066 (OMIM: 600543,615515) PREDICTED: receptor (1349 aa) initn: 5970 init1: 4686 opt: 4753 Z-score: 1708.3 bits: 328.4 E(85289): 2.1e-88 Smith-Waterman score: 8979; 96.9% identity (96.9% similar) in 1340 aa overlap (10-1308:10-1349) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 pF1KE2 NGSSGC--------------------------GRCHKSCTGRCWGPTENHCQTLTRTVCA :::::: :::::::::::::::::::::::::::: XP_016 NGSSGCLAHQDTEKNNPQLLQSLQPFSLITPGGRCHKSCTGRCWGPTENHCQTLTRTVCA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE2 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE2 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE2 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE2 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE2 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE2 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP 550 560 570 580 590 600 580 590 600 610 620 pF1KE2 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGC--------- ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCIGSSIEDCI 610 620 630 640 650 660 630 640 650 660 670 pF1KE2 ------NGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLMDRCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKS 670 680 690 700 710 720 680 690 700 710 720 730 pF1KE2 IKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVP 730 740 750 760 770 780 740 750 760 770 780 790 pF1KE2 EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLM 790 800 810 820 830 840 800 810 820 830 840 850 pF1KE2 PHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKI 850 860 870 880 890 900 860 870 880 890 900 910 pF1KE2 TDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGK 910 920 930 940 950 960 920 930 940 950 960 970 pF1KE2 PYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMAR 970 980 990 1000 1010 1020 980 990 1000 1010 1020 1030 pF1KE2 DPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRA 1030 1040 1050 1060 1070 1080 1040 1050 1060 1070 1080 1090 pF1KE2 RIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATA 1090 1100 1110 1120 1130 1140 1100 1110 1120 1130 1140 1150 pF1KE2 EIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPK 1150 1160 1170 1180 1190 1200 1160 1170 1180 1190 1200 1210 pF1KE2 QEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKA 1210 1220 1230 1240 1250 1260 1220 1230 1240 1250 1260 1270 pF1KE2 EYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVA 1270 1280 1290 1300 1310 1320 1280 1290 1300 pF1KE2 ENPEYLSEFSLKPGTVLPPPPYRHRNTVV ::::::::::::::::::::::::::::: XP_016 ENPEYLSEFSLKPGTVLPPPPYRHRNTVV 1330 1340 >>XP_006712427 (OMIM: 600543,615515) PREDICTED: receptor (1323 aa) initn: 4686 init1: 4686 opt: 4752 Z-score: 1708.0 bits: 328.3 E(85289): 2.1e-88 Smith-Waterman score: 9107; 98.9% identity (98.9% similar) in 1323 aa overlap (1-1308:1-1323) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA 550 560 570 580 590 600 610 620 630 640 pF1KE2 NSFIFKYADPDRECHPCHPNCTQGC---------------NGPTSHDCIYYPWTGHSTLP ::::::::::::::::::::::::: :::::::::::::::::::: XP_006 NSFIFKYADPDRECHPCHPNCTQGCIGSSIEDCIGLMDRCNGPTSHDCIYYPWTGHSTLP 610 620 630 640 650 660 650 660 670 680 690 700 pF1KE2 QHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAP 670 680 690 700 710 720 710 720 730 740 750 760 pF1KE2 NQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEF 730 740 750 760 770 780 770 780 790 800 810 820 pF1KE2 MDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCV 790 800 810 820 830 840 830 840 850 860 870 880 pF1KE2 QIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIK 850 860 870 880 890 900 890 900 910 920 930 940 pF1KE2 WMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPIC 910 920 930 940 950 960 950 960 970 980 990 1000 pF1KE2 TIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQ 970 980 990 1000 1010 1020 1010 1020 1030 1040 1050 1060 pF1KE2 NLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFV 1030 1040 1050 1060 1070 1080 1070 1080 1090 1100 1110 1120 pF1KE2 YRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSST 1090 1100 1110 1120 1130 1140 1130 1140 1150 1160 1170 1180 pF1KE2 QRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDN 1150 1160 1170 1180 1190 1200 1190 1200 1210 1220 1230 1240 pF1KE2 PEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNH 1210 1220 1230 1240 1250 1260 1250 1260 1270 1280 1290 1300 pF1KE2 SLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRN 1270 1280 1290 1300 1310 1320 pF1KE2 TVV ::: XP_006 TVV >>XP_016859071 (OMIM: 600543,615515) PREDICTED: receptor (1116 aa) initn: 4686 init1: 4686 opt: 4748 Z-score: 1707.4 bits: 328.0 E(85289): 2.3e-88 Smith-Waterman score: 7691; 98.6% identity (98.7% similar) in 1116 aa overlap (208-1308:1-1116) 180 190 200 210 220 230 pF1KE2 VSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGG .::::::::::::::::::::::::::::: XP_016 MTRTVCAEQCDGRCYGPYVSDCCHRECAGG 10 20 30 240 250 260 270 280 290 pF1KE2 CSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNF 40 50 60 70 80 90 300 310 320 330 340 350 pF1KE2 VVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFI 100 110 120 130 140 150 360 370 380 390 400 410 pF1KE2 NCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVF 160 170 180 190 200 210 420 430 440 450 460 470 pF1KE2 SNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTL 220 230 240 250 260 270 480 490 500 510 520 530 pF1KE2 FSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCN 280 290 300 310 320 330 540 550 560 570 580 590 pF1KE2 LYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGL 340 350 360 370 380 390 600 610 620 630 640 pF1KE2 QGANSFIFKYADPDRECHPCHPNCTQGC---------------NGPTSHDCIYYPWTGHS :::::::::::::::::::::::::::: ::::::::::::::::: XP_016 QGANSFIFKYADPDRECHPCHPNCTQGCIGSSIEDCIGLMDRCNGPTSHDCIYYPWTGHS 400 410 420 430 440 450 650 660 670 680 690 700 pF1KE2 TLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSG 460 470 480 490 500 510 710 720 730 740 750 760 pF1KE2 TAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKAN 520 530 540 550 560 570 770 780 790 800 810 820 pF1KE2 VEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLN 580 590 600 610 620 630 830 840 850 860 870 880 pF1KE2 WCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKM 640 650 660 670 680 690 890 900 910 920 930 940 pF1KE2 PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQP 700 710 720 730 740 750 950 960 970 980 990 1000 pF1KE2 PICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSK 760 770 780 790 800 810 1010 1020 1030 1040 1050 1060 pF1KE2 FFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGN 820 830 840 850 860 870 1070 1080 1090 1100 1110 1120 pF1KE2 QFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQED 880 890 900 910 920 930 1130 1140 1150 1160 1170 1180 pF1KE2 SSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQA 940 950 960 970 980 990 1190 1200 1210 1220 1230 1240 pF1KE2 LDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDY 1000 1010 1020 1030 1040 1050 1250 1260 1270 1280 1290 1300 pF1KE2 WNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYR 1060 1070 1080 1090 1100 1110 pF1KE2 HRNTVV :::::: XP_016 HRNTVV >>XP_016859069 (OMIM: 600543,615515) PREDICTED: receptor (1324 aa) initn: 8966 init1: 4491 opt: 4559 Z-score: 1639.9 bits: 315.7 E(85289): 1.3e-84 Smith-Waterman score: 8895; 96.6% identity (96.8% similar) in 1334 aa overlap (1-1308:1-1324) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 pF1KE2 NGSSGC--------------------------GRCHKSCTGRCWGPTENHCQTLTRTVCA :::::: :::::::::::::::::::::::::::: XP_016 NGSSGCLAHQDTEKNNPQLLQSLQPFSLITPGGRCHKSCTGRCWGPTENHCQTLTRTVCA 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE2 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQ 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE2 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKAC 310 320 330 340 350 360 340 350 360 370 380 390 pF1KE2 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRT 370 380 390 400 410 420 400 410 420 430 440 450 pF1KE2 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEIS 430 440 450 460 470 480 460 470 480 490 500 510 pF1KE2 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWG 490 500 510 520 530 540 520 530 540 550 560 570 pF1KE2 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGP 550 560 570 580 590 600 580 590 600 610 620 630 pF1KE2 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCI ::::::::::::::::::::::::::::::::::::::::::::::::::: : . .::: XP_016 DNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCIGSSIEDCI 610 620 630 640 650 660 640 650 660 670 680 690 pF1KE2 YYPWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETEL :::::::::::::::::::::::::::::::::::::::::::::: XP_016 GL----------MDRTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETEL 670 680 690 700 710 700 710 720 730 740 750 pF1KE2 VEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILN 720 730 740 750 760 770 760 770 780 790 800 810 pF1KE2 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDN 780 790 800 810 820 830 820 830 840 850 860 870 pF1KE2 IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKE 840 850 860 870 880 890 880 890 900 910 920 930 pF1KE2 YNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLE 900 910 920 930 940 950 940 950 960 970 980 990 pF1KE2 KGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMK 960 970 980 990 1000 1010 1000 1010 1020 1030 1040 1050 pF1KE2 LPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPP 1020 1030 1040 1050 1060 1070 1060 1070 1080 1090 1100 1110 pF1KE2 AYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKP 1080 1090 1100 1110 1120 1130 1120 1130 1140 1150 1160 1170 pF1KE2 VAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSR 1140 1150 1160 1170 1180 1190 1180 1190 1200 1210 1220 1230 pF1KE2 RKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAK 1200 1210 1220 1230 1240 1250 1240 1250 1260 1270 1280 1290 pF1KE2 KAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGT 1260 1270 1280 1290 1300 1310 1300 pF1KE2 VLPPPPYRHRNTVV :::::::::::::: XP_016 VLPPPPYRHRNTVV 1320 >>XP_005246434 (OMIM: 600543,615515) PREDICTED: receptor (1282 aa) initn: 7161 init1: 4503 opt: 4503 Z-score: 1620.3 bits: 312.1 E(85289): 1.6e-83 Smith-Waterman score: 8798; 97.3% identity (97.5% similar) in 1308 aa overlap (1-1308:1-1282) 10 20 30 40 50 60 pF1KE2 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKPATGLWVWVSLLVAAGTVQPSDSQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNLEITSIEHNRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYD 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 NSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG ::::::::::::::::::::::::: : . .::: :::::::::::: XP_005 NSFIFKYADPDRECHPCHPNCTQGCIGSSIEDCIGL----------MDRTPLIAAGVIGG 610 620 630 640 650 670 680 690 700 710 720 pF1KE2 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KE2 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL 720 730 740 750 760 770 790 800 810 820 830 840 pF1KE2 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV 780 790 800 810 820 830 850 860 870 880 890 900 pF1KE2 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ 840 850 860 870 880 890 910 920 930 940 950 960 pF1KE2 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID 900 910 920 930 940 950 970 980 990 1000 1010 1020 pF1KE2 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE 960 970 980 990 1000 1010 1030 1040 1050 1060 1070 1080 pF1KE2 EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVP ::::::::::::::::::::::::: ::::::::::::::::::: XP_005 EYLVPQAFNIPPPIYTSRARIDSNR----------------NQFVYRDGGFAAEQGVSVP 1020 1030 1040 1050 1090 1100 1110 1120 1130 1140 pF1KE2 YRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERS 1060 1070 1080 1090 1100 1110 1150 1160 1170 1180 1190 1200 pF1KE2 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED 1120 1130 1140 1150 1160 1170 1210 1220 1230 1240 1250 1260 pF1KE2 EYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ 1180 1190 1200 1210 1220 1230 1270 1280 1290 1300 pF1KE2 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV :::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV 1240 1250 1260 1270 1280 1308 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 18:04:17 2016 done: Sun Nov 6 18:04:19 2016 Total Scan time: 16.230 Total Display time: 0.790 Function used was FASTA [36.3.4 Apr, 2011]