Result of FASTA (omim) for
pF1KE2321
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2321, 1434 aa
1>>>pF1KE2321 1434 - 1434 aa - 1434 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9973+/-0.000503; mu= 11.0556+/- 0.031
mean_var=231.1589+/-48.916, 0's: 0 Z-trim(114.6): 97 B-trim: 0 in 0/56
Lambda= 0.084357
statistics sampled from 24495 (24591) to 24495 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.288), width: 16
Scan time: 17.990
The best scores are: opt bits E(85289)
XP_016874836 (OMIM: 163731) PREDICTED: nitric oxid (1434) 9718 1197.9 0
NP_000611 (OMIM: 163731) nitric oxide synthase, br (1434) 9718 1197.9 0
NP_001191142 (OMIM: 163731) nitric oxide synthase, (1098) 7465 923.6 0
NP_001191143 (OMIM: 163731) nitric oxide synthase, (1098) 7465 923.6 0
XP_016874835 (OMIM: 163731) PREDICTED: nitric oxid (1468) 5758 715.9 5.4e-205
XP_011536700 (OMIM: 163731) PREDICTED: nitric oxid (1468) 5758 715.9 5.4e-205
NP_001191147 (OMIM: 163731) nitric oxide synthase, (1468) 5758 715.9 5.4e-205
XP_016874834 (OMIM: 163731) PREDICTED: nitric oxid (1468) 5758 715.9 5.4e-205
XP_016867721 (OMIM: 104300,145500,163729,189800,60 (1203) 4727 590.4 2.8e-167
NP_000594 (OMIM: 104300,145500,163729,189800,60136 (1203) 4727 590.4 2.8e-167
XP_016867722 (OMIM: 104300,145500,163729,189800,60 ( 997) 4199 526.0 5.4e-148
XP_006716065 (OMIM: 104300,145500,163729,189800,60 ( 705) 2877 365.0 1.2e-99
XP_016867723 (OMIM: 104300,145500,163729,189800,60 ( 751) 2877 365.0 1.2e-99
NP_001153582 (OMIM: 104300,145500,163729,189800,60 ( 614) 2466 314.9 1.2e-84
NP_001153581 (OMIM: 104300,145500,163729,189800,60 ( 596) 2444 312.2 7.6e-84
NP_001153583 (OMIM: 104300,145500,163729,189800,60 ( 629) 2444 312.2 7.9e-84
XP_011523163 (OMIM: 145500,163730,611162) PREDICTE (1129) 2399 307.0 5.2e-82
NP_000616 (OMIM: 145500,163730,611162) nitric oxid (1153) 2399 307.0 5.3e-82
XP_011523161 (OMIM: 145500,163730,611162) PREDICTE (1153) 2399 307.0 5.3e-82
XP_011523162 (OMIM: 145500,163730,611162) PREDICTE (1152) 2395 306.5 7.4e-82
XP_011523164 (OMIM: 145500,163730,611162) PREDICTE ( 931) 1884 244.3 3.4e-63
NP_000932 (OMIM: 124015,201750,207410,613571) NADP ( 680) 661 95.3 1.7e-18
NP_001137498 (OMIM: 606073) NADPH-dependent diflav ( 606) 638 92.4 1.1e-17
XP_011516849 (OMIM: 606073) PREDICTED: NADPH-depen ( 537) 634 91.9 1.4e-17
NP_055249 (OMIM: 606073) NADPH-dependent diflavin ( 597) 599 87.7 3e-16
XP_011516847 (OMIM: 606073) PREDICTED: NADPH-depen ( 572) 581 85.5 1.3e-15
XP_011516850 (OMIM: 606073) PREDICTED: NADPH-depen ( 332) 540 80.2 2.9e-14
XP_016870116 (OMIM: 606073) PREDICTED: NADPH-depen ( 555) 544 80.9 2.9e-14
XP_016870115 (OMIM: 606073) PREDICTED: NADPH-depen ( 564) 532 79.5 8.1e-14
NP_001137499 (OMIM: 606073) NADPH-dependent diflav ( 521) 487 74.0 3.4e-12
NP_001137500 (OMIM: 606073) NADPH-dependent diflav ( 590) 386 61.7 1.9e-08
NP_002445 (OMIM: 236270,601634,602568) methionine ( 698) 289 50.0 7.5e-05
NP_076915 (OMIM: 236270,601634,602568) methionine ( 725) 289 50.0 7.7e-05
>>XP_016874836 (OMIM: 163731) PREDICTED: nitric oxide sy (1434 aa)
initn: 9718 init1: 9718 opt: 9718 Z-score: 6406.0 bits: 1197.9 E(85289): 0
Smith-Waterman score: 9718; 100.0% identity (100.0% similar) in 1434 aa overlap (1-1434:1-1434)
10 20 30 40 50 60
pF1KE2 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 EERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 GHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 SLISNDRSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLISNDRSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 ISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 EEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 SYRTRDGEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYRTRDGEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 FRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSRE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 PDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE2 DAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
1390 1400 1410 1420 1430
>>NP_000611 (OMIM: 163731) nitric oxide synthase, brain (1434 aa)
initn: 9718 init1: 9718 opt: 9718 Z-score: 6406.0 bits: 1197.9 E(85289): 0
Smith-Waterman score: 9718; 100.0% identity (100.0% similar) in 1434 aa overlap (1-1434:1-1434)
10 20 30 40 50 60
pF1KE2 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 EERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EERKSYKVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 GHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GHAVDTLLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANN
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 SLISNDRSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLISNDRSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RLHTNGSQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 ISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ISNWTDELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEY
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 EEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEWKWGKNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIV
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 SYRTRDGEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SYRTRDGEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 FRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSRE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 PDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PDKPKKYVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE2 DAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DAGVFISRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
1390 1400 1410 1420 1430
>>NP_001191142 (OMIM: 163731) nitric oxide synthase, bra (1098 aa)
initn: 7465 init1: 7465 opt: 7465 Z-score: 4925.5 bits: 923.6 E(85289): 0
Smith-Waterman score: 7465; 100.0% identity (100.0% similar) in 1098 aa overlap (337-1434:1-1098)
310 320 330 340 350 360
pF1KE2 KVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLFPLAKEF
::::::::::::::::::::::::::::::
NP_001 MGSIMHPSQHARRPEDVRTKGQLFPLAKEF
10 20 30
370 380 390 400 410 420
pF1KE2 IDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQW
40 50 60 70 80 90
430 440 450 460 470 480
pF1KE2 SKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIR
100 110 120 130 140 150
490 500 510 520 530 540
pF1KE2 YAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELV
160 170 180 190 200 210
550 560 570 580 590 600
pF1KE2 LEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDN
220 230 240 250 260 270
610 620 630 640 650 660
pF1KE2 SRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKH
280 290 300 310 320 330
670 680 690 700 710 720
pF1KE2 MENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNG
340 350 360 370 380 390
730 740 750 760 770 780
pF1KE2 TPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAF
400 410 420 430 440 450
790 800 810 820 830 840
pF1KE2 DAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSY
460 470 480 490 500 510
850 860 870 880 890 900
pF1KE2 KVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDT
520 530 540 550 560 570
910 920 930 940 950 960
pF1KE2 LLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISND
580 590 600 610 620 630
970 980 990 1000 1010 1020
pF1KE2 RSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNG
640 650 660 670 680 690
1030 1040 1050 1060 1070 1080
pF1KE2 SQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTD
700 710 720 730 740 750
1090 1100 1110 1120 1130 1140
pF1KE2 ELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWG
760 770 780 790 800 810
1150 1160 1170 1180 1190 1200
pF1KE2 KNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRD
820 830 840 850 860 870
1210 1220 1230 1240 1250 1260
pF1KE2 GEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQ
880 890 900 910 920 930
1270 1280 1290 1300 1310 1320
pF1KE2 QRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKK
940 950 960 970 980 990
1330 1340 1350 1360 1370 1380
pF1KE2 YVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFI
1000 1010 1020 1030 1040 1050
1390 1400 1410 1420 1430
pF1KE2 SRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
1060 1070 1080 1090
>>NP_001191143 (OMIM: 163731) nitric oxide synthase, bra (1098 aa)
initn: 7465 init1: 7465 opt: 7465 Z-score: 4925.5 bits: 923.6 E(85289): 0
Smith-Waterman score: 7465; 100.0% identity (100.0% similar) in 1098 aa overlap (337-1434:1-1098)
310 320 330 340 350 360
pF1KE2 KVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLFPLAKEF
::::::::::::::::::::::::::::::
NP_001 MGSIMHPSQHARRPEDVRTKGQLFPLAKEF
10 20 30
370 380 390 400 410 420
pF1KE2 IDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQW
40 50 60 70 80 90
430 440 450 460 470 480
pF1KE2 SKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIR
100 110 120 130 140 150
490 500 510 520 530 540
pF1KE2 YAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELV
160 170 180 190 200 210
550 560 570 580 590 600
pF1KE2 LEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDN
220 230 240 250 260 270
610 620 630 640 650 660
pF1KE2 SRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKH
280 290 300 310 320 330
670 680 690 700 710 720
pF1KE2 MENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNG
340 350 360 370 380 390
730 740 750 760 770 780
pF1KE2 TPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAF
400 410 420 430 440 450
790 800 810 820 830 840
pF1KE2 DAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSY
460 470 480 490 500 510
850 860 870 880 890 900
pF1KE2 KVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVRFNSVSSYSDSQKSSGDGPDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDT
520 530 540 550 560 570
910 920 930 940 950 960
pF1KE2 LLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLEELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISND
580 590 600 610 620 630
970 980 990 1000 1010 1020
pF1KE2 RSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSWKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNG
640 650 660 670 680 690
1030 1040 1050 1060 1070 1080
pF1KE2 SQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTD
700 710 720 730 740 750
1090 1100 1110 1120 1130 1140
pF1KE2 ELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELRLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWG
760 770 780 790 800 810
1150 1160 1170 1180 1190 1200
pF1KE2 KNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNPTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRD
820 830 840 850 860 870
1210 1220 1230 1240 1250 1260
pF1KE2 GEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEGPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQ
880 890 900 910 920 930
1270 1280 1290 1300 1310 1320
pF1KE2 QRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRQFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKK
940 950 960 970 980 990
1330 1340 1350 1360 1370 1380
pF1KE2 YVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVQDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFI
1000 1010 1020 1030 1040 1050
1390 1400 1410 1420 1430
pF1KE2 SRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRMRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
1060 1070 1080 1090
>>XP_016874835 (OMIM: 163731) PREDICTED: nitric oxide sy (1468 aa)
initn: 5758 init1: 5758 opt: 5758 Z-score: 3801.3 bits: 715.9 E(85289): 5.4e-205
Smith-Waterman score: 9630; 97.7% identity (97.7% similar) in 1466 aa overlap (1-1432:1-1466)
10 20 30 40 50 60
pF1KE2 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
790 800 810 820 830 840
850 860
pF1KE2 EERK----------------------------------SYKVRFNSVSSYSDSQKSSGDG
:::: ::::::::::::::::::::::
XP_016 EERKYPEPLRFFPRKGPPLPNGDTEVHGLAAARDSQHRSYKVRFNSVSSYSDSQKSSGDG
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE2 PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE2 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE2 QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE2 DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDIT
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE2 TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KE2 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KE2 ELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KE2 GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KE2 QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
1390 1400 1410 1420 1430 1440
1410 1420 1430
pF1KE2 YEVTNRLRSESIAFIEESKKDTDEVFSS
::::::::::::::::::::::::::
XP_016 YEVTNRLRSESIAFIEESKKDTDEVFSS
1450 1460
>>XP_011536700 (OMIM: 163731) PREDICTED: nitric oxide sy (1468 aa)
initn: 5758 init1: 5758 opt: 5758 Z-score: 3801.3 bits: 715.9 E(85289): 5.4e-205
Smith-Waterman score: 9630; 97.7% identity (97.7% similar) in 1466 aa overlap (1-1432:1-1466)
10 20 30 40 50 60
pF1KE2 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
790 800 810 820 830 840
850 860
pF1KE2 EERK----------------------------------SYKVRFNSVSSYSDSQKSSGDG
:::: ::::::::::::::::::::::
XP_011 EERKYPEPLRFFPRKGPPLPNGDTEVHGLAAARDSQHRSYKVRFNSVSSYSDSQKSSGDG
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE2 PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE2 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE2 QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE2 DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDIT
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE2 TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KE2 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KE2 ELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KE2 GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KE2 QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
1390 1400 1410 1420 1430 1440
1410 1420 1430
pF1KE2 YEVTNRLRSESIAFIEESKKDTDEVFSS
::::::::::::::::::::::::::
XP_011 YEVTNRLRSESIAFIEESKKDTDEVFSS
1450 1460
>>NP_001191147 (OMIM: 163731) nitric oxide synthase, bra (1468 aa)
initn: 5758 init1: 5758 opt: 5758 Z-score: 3801.3 bits: 715.9 E(85289): 5.4e-205
Smith-Waterman score: 9630; 97.7% identity (97.7% similar) in 1466 aa overlap (1-1432:1-1466)
10 20 30 40 50 60
pF1KE2 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
790 800 810 820 830 840
850 860
pF1KE2 EERK----------------------------------SYKVRFNSVSSYSDSQKSSGDG
:::: ::::::::::::::::::::::
NP_001 EERKYPEPLRFFPRKGPPLPNGDTEVHGLAAARDSQHRSYKVRFNSVSSYSDSQKSSGDG
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE2 PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE2 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE2 QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE2 DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDIT
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE2 TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KE2 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KE2 ELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KE2 GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KE2 QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
1390 1400 1410 1420 1430 1440
1410 1420 1430
pF1KE2 YEVTNRLRSESIAFIEESKKDTDEVFSS
::::::::::::::::::::::::::
NP_001 YEVTNRLRSESIAFIEESKKDTDEVFSS
1450 1460
>>XP_016874834 (OMIM: 163731) PREDICTED: nitric oxide sy (1468 aa)
initn: 5758 init1: 5758 opt: 5758 Z-score: 3801.3 bits: 715.9 E(85289): 5.4e-205
Smith-Waterman score: 9630; 97.7% identity (97.7% similar) in 1466 aa overlap (1-1432:1-1466)
10 20 30 40 50 60
pF1KE2 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVTQPLGPPTKAVDLSHQPPAGKEQPLAVDGASGPGNGPQHAYDDGQEAGSLPHANGLAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPPGQDPAKKATRVSLQGRGENNELLKEIEPVLSLLTSGSRGVKGGAPAKAEMKDMGIQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGSPS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCPRFLKVKNWETEVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPEDVRTKGQLF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
790 800 810 820 830 840
850 860
pF1KE2 EERK----------------------------------SYKVRFNSVSSYSDSQKSSGDG
:::: ::::::::::::::::::::::
XP_016 EERKYPEPLRFFPRKGPPLPNGDTEVHGLAAARDSQHRSYKVRFNSVSSYSDSQKSSGDG
850 860 870 880 890 900
870 880 890 900 910 920
pF1KE2 PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
910 920 930 940 950 960
930 940 950 960 970 980
pF1KE2 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELT
970 980 990 1000 1010 1020
990 1000 1010 1020 1030 1040
pF1KE2 QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
1030 1040 1050 1060 1070 1080
1050 1060 1070 1080 1090 1100
pF1KE2 DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDIT
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE2 TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
1150 1160 1170 1180 1190 1200
1170 1180 1190 1200 1210 1220
pF1KE2 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
1210 1220 1230 1240 1250 1260
1230 1240 1250 1260 1270 1280
pF1KE2 ELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVF
1270 1280 1290 1300 1310 1320
1290 1300 1310 1320 1330 1340
pF1KE2 GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKE
1330 1340 1350 1360 1370 1380
1350 1360 1370 1380 1390 1400
pF1KE2 QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFGVTLRT
1390 1400 1410 1420 1430 1440
1410 1420 1430
pF1KE2 YEVTNRLRSESIAFIEESKKDTDEVFSS
::::::::::::::::::::::::::
XP_016 YEVTNRLRSESIAFIEESKKDTDEVFSS
1450 1460
>>XP_016867721 (OMIM: 104300,145500,163729,189800,601367 (1203 aa)
initn: 4199 init1: 1917 opt: 4727 Z-score: 3124.2 bits: 590.4 E(85289): 2.8e-167
Smith-Waterman score: 4727; 59.6% identity (82.1% similar) in 1144 aa overlap (285-1422:47-1182)
260 270 280 290 300 310
pF1KE2 GVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGS-PSKCPRFLKVKNWET
::. .. :.. . : . :.: .:::::.
XP_016 LGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEV
20 30 40 50 60 70
320 330 340 350 360 370
pF1KE2 EVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPED-VRTKGQLFPLAKEFIDQYYS
. ::: .. . :: :.::.. : . :: . ::. :..::.::::
XP_016 GSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPEQLLSQARDFINQYYS
80 90 100 110 120 130
380 390 400 410 420 430
pF1KE2 SIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVF
:::: ::.:: .::.::. :. .:.::::...::..:::.::::: ::::::::.:::::
XP_016 SIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVF
140 150 160 170 180 190
440 450 460 470 480 490
pF1KE2 DARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQ
::::: .:. ::.:::::.:::::.::::::::.:::: :. :::.:::::.:::::.:
XP_016 DARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQ
200 210 220 230 240 250
500 510 520 530 540 550
pF1KE2 PDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIR
:::. ::::::..::.:::.:: : :::::::::::: . :::: .:::::::::..
XP_016 QDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPELFLLPPELVLEVPLE
260 270 280 290 300 310
560 570 580 590 600 610
pF1KE2 HPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNIL
:: .::: :::.::.:::::::::::::::: : :::::::.::::.:. :: :::::
XP_016 HPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNIL
320 330 340 350 360 370
620 630 640 650 660 670
pF1KE2 EEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYR
:.:: :.:: : :::::::.: ::::.:::.:.: ::::::::.:: ::.::.::: .
XP_016 EDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQK
380 390 400 410 420 430
680 690 700 710 720 730
pF1KE2 CRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTPTKRR
::::::::.:::::.:::.::::::::.:: :.:.:.::::::. . ::: : :.
XP_016 ARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAKGT-GITRKKT
440 450 460 470 480 490
740 750 760 770 780 790
pF1KE2 AIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMS
::..:.:::.::.::: .:::::::::::..:::..:.::. : ..:..::: .:.
XP_016 ---FKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLC
500 510 520 530 540 550
800 810 820 830 840
pF1KE2 MEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHP-NSVQ--EERKSYKVR
:.:::.: ::::::::::::::::::::::::.:. ::::: : :: :..::::.:
XP_016 MDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIR
560 570 580 590 600 610
850 860 870 880 890 900
pF1KE2 FNSVSSYSDSQKSSGDGPDLRD-NFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLL
:::.: :: :: .. : .::: :...:: :::::::::::::::..:::: :
XP_016 FNSISC-SDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRL
620 630 640 650 660 670
910 920 930 940 950 960
pF1KE2 EELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRS
:::::::.:.. .:::::::::::: ::. .:.:::..::::.:. . : ...: ::
XP_016 EELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDA--KAAARDIFSPKRS
680 690 700 710 720
970 980 990 1000 1010 1020
pF1KE2 WKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQ
:::...::. ::. .: :: .::.... : . : .:::: ::.:.::.::: :.:..
XP_016 WKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRATILVRLDTGGQE
730 740 750 760 770 780
1030 1040 1050 1060 1070 1080
pF1KE2 ELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDEL
::::::::.:: : :. ::.::. :.:: : .. : :: :: ... : .:. .
XP_016 GLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLE-KGSPGGPPPGWVRDP
790 800 810 820 830 840
1090 1100 1110 1120 1130 1140
pF1KE2 RLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKN
::::::. ::. ..::::.::.: :. ...:: .:.:.: .::. ..:::::: .
XP_016 RLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRC
850 860 870 880 890 900
1150 1160 1170 1180 1190 1200
pF1KE2 PTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGE
::..::::.:::. .:: :::::: ::::::::.::.:. .: :.:::::...:::.::
XP_016 PTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGL
910 920 930 940 950 960
1210 1220 1230 1240 1250 1260
pF1KE2 GPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQR
::.:.::::.::.... . ::::.::::::.:: .:..:::::::::::::::.:::.:
XP_016 GPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQER
970 980 990 1000 1010 1020
1270 1280 1290 1300 1310 1320
pF1KE2 QFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYV
::. ::..: ::.:::::: :..::.::.:. .:...::: .. ::.:::::.:: ::
XP_016 LHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYV
1030 1040 1050 1060 1070 1080
1330 1340 1350 1360 1370 1380
pF1KE2 QDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISR
::::. .:: :.:.: . ::..::::::::..::...:::.. .: . ..:: :.
XP_016 QDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELDEAGDVIGV
1090 1100 1110 1120 1130 1140
1390 1400 1410 1420 1430
pF1KE2 MRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
.::..::::::::.:::: :::.:.:..:... :
XP_016 LRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDTNSP
1150 1160 1170 1180 1190 1200
>>NP_000594 (OMIM: 104300,145500,163729,189800,601367) n (1203 aa)
initn: 4199 init1: 1917 opt: 4727 Z-score: 3124.2 bits: 590.4 E(85289): 2.8e-167
Smith-Waterman score: 4727; 59.6% identity (82.1% similar) in 1144 aa overlap (285-1422:47-1182)
260 270 280 290 300 310
pF1KE2 GVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPTSGKQSPTKNGS-PSKCPRFLKVKNWET
::. .. :.. . : . :.: .:::::.
NP_000 LGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEV
20 30 40 50 60 70
320 330 340 350 360 370
pF1KE2 EVVLTDTLHLKSTLETGCTEYICMGSIMHPSQHARRPED-VRTKGQLFPLAKEFIDQYYS
. ::: .. . :: :.::.. : . :: . ::. :..::.::::
NP_000 GSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPEQLLSQARDFINQYYS
80 90 100 110 120 130
380 390 400 410 420 430
pF1KE2 SIKRFGSKAHMERLEEVNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVF
:::: ::.:: .::.::. :. .:.::::...::..:::.::::: ::::::::.:::::
NP_000 SIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVF
140 150 160 170 180 190
440 450 460 470 480 490
pF1KE2 DARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQ
::::: .:. ::.:::::.:::::.::::::::.:::: :. :::.:::::.:::::.:
NP_000 DARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDFRIWNSQLVRYAGYRQ
200 210 220 230 240 250
500 510 520 530 540 550
pF1KE2 PDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIR
:::. ::::::..::.:::.:: : :::::::::::: . :::: .:::::::::..
NP_000 QDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPELFLLPPELVLEVPLE
260 270 280 290 300 310
560 570 580 590 600 610
pF1KE2 HPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNIL
:: .::: :::.::.:::::::::::::::: : :::::::.::::.:. :: :::::
NP_000 HPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTEIGTRNLCDPHRYNIL
320 330 340 350 360 370
620 630 640 650 660 670
pF1KE2 EEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYR
:.:: :.:: : :::::::.: ::::.:::.:.: ::::::::.:: ::.::.::: .
NP_000 EDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHHAATASFMKHLENEQK
380 390 400 410 420 430
680 690 700 710 720 730
pF1KE2 CRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTPTKRR
::::::::.:::::.:::.::::::::.:: :.:.:.::::::. . ::: : :.
NP_000 ARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAKGT-GITRKKT
440 450 460 470 480 490
740 750 760 770 780 790
pF1KE2 AIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMS
::..:.:::.::.::: .:::::::::::..:::..:.::. : ..:..::: .:.
NP_000 ---FKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLC
500 510 520 530 540 550
800 810 820 830 840
pF1KE2 MEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHP-NSVQ--EERKSYKVR
:.:::.: ::::::::::::::::::::::::.:. ::::: : :: :..::::.:
NP_000 MDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIR
560 570 580 590 600 610
850 860 870 880 890 900
pF1KE2 FNSVSSYSDSQKSSGDGPDLRD-NFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLL
:::.: :: :: .. : .::: :...:: :::::::::::::::..:::: :
NP_000 FNSISC-SDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRL
620 630 640 650 660 670
910 920 930 940 950 960
pF1KE2 EELGGERILKMREGDELCGQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRS
:::::::.:.. .:::::::::::: ::. .:.:::..::::.:. . : ...: ::
NP_000 EELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDA--KAAARDIFSPKRS
680 690 700 710 720
970 980 990 1000 1010 1020
pF1KE2 WKRNKFRLTFVAEAPELTQGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQ
:::...::. ::. .: :: .::.... : . : .:::: ::.:.::.::: :.:..
NP_000 WKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRATILVRLDTGGQE
730 740 750 760 770 780
1030 1040 1050 1060 1070 1080
pF1KE2 ELQYQPGDHLGVFPGNHEDLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDEL
::::::::.:: : :. ::.::. :.:: : .. : :: :: ... : .:. .
NP_000 GLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLE-KGSPGGPPPGWVRDP
790 800 810 820 830 840
1090 1100 1110 1120 1130 1140
pF1KE2 RLPPCTIFQAFKYYLDITTPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKN
::::::. ::. ..::::.::.: :. ...:: .:.:.: .::. ..:::::: .
NP_000 RLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRYEEWKWFRC
850 860 870 880 890 900
1150 1160 1170 1180 1190 1200
pF1KE2 PTIVEVLEEFPSIQMPATLLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGE
::..::::.:::. .:: :::::: ::::::::.::.:. .: :.:::::...:::.::
NP_000 PTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAVLAYRTQDGL
910 920 930 940 950 960
1210 1220 1230 1240 1250 1260
pF1KE2 GPIHHGVCSSWLNRIQADELVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQR
::.:.::::.::.... . ::::.::::::.:: .:..:::::::::::::::.:::.:
NP_000 GPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAPFRGFWQER
970 980 990 1000 1010 1020
1270 1280 1290 1300 1310 1320
pF1KE2 QFDIQHKGMNPCPMVLVFGCRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYV
::. ::..: ::.:::::: :..::.::.:. .:...::: .. ::.:::::.:: ::
NP_000 LHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSREPDNPKTYV
1030 1040 1050 1060 1070 1080
1330 1340 1350 1360 1370 1380
pF1KE2 QDILQEQLAESVYRALKEQGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISR
::::. .:: :.:.: . ::..::::::::..::...:::.. .: . ..:: :.
NP_000 QDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELDEAGDVIGV
1090 1100 1110 1120 1130 1140
1390 1400 1410 1420 1430
pF1KE2 MRDDNRYHEDIFGVTLRTYEVTNRLRSESIAFIEESKKDTDEVFSS
.::..::::::::.:::: :::.:.:..:... :
NP_000 LRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPGSDTNSP
1150 1160 1170 1180 1190 1200
1434 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:38:12 2016 done: Sun Nov 6 09:38:15 2016
Total Scan time: 17.990 Total Display time: 0.740
Function used was FASTA [36.3.4 Apr, 2011]