FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2322, 1335 aa 1>>>pF1KE2322 1335 - 1335 aa - 1335 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8145+/-0.00112; mu= 10.7180+/- 0.067 mean_var=125.4528+/-25.481, 0's: 0 Z-trim(106.3): 26 B-trim: 0 in 0/50 Lambda= 0.114508 statistics sampled from 9029 (9043) to 9029 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.271), width: 16 Scan time: 2.510 The best scores are: opt bits E(33420) CCDS11773.1 RPTOR gene_id:57521|Hs109|chr17 (1335) 9008 1500.5 0 CCDS54175.1 RPTOR gene_id:57521|Hs109|chr17 (1177) 4501 756.0 1.4e-217 >>CCDS11773.1 RPTOR gene_id:57521|Hs109|chr17 (1335 aa) initn: 9008 init1: 9008 opt: 9008 Z-score: 8042.9 bits: 1500.5 E(33420): 0 Smith-Waterman score: 9008; 100.0% identity (100.0% similar) in 1335 aa overlap (1-1335:1-1335) 10 20 30 40 50 60 pF1KE2 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS 1270 1280 1290 1300 1310 1320 1330 pF1KE2 NDYYISVYSVEKRVR ::::::::::::::: CCDS11 NDYYISVYSVEKRVR 1330 >>CCDS54175.1 RPTOR gene_id:57521|Hs109|chr17 (1177 aa) initn: 4501 init1: 4501 opt: 4501 Z-score: 4019.8 bits: 756.0 E(33420): 1.4e-217 Smith-Waterman score: 7599; 88.2% identity (88.2% similar) in 1335 aa overlap (1-1335:1-1177) 10 20 30 40 50 60 pF1KE2 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA ::::::::::::::::::::::: CCDS54 QSSARELRPLLVFIWAKILAVDS------------------------------------- 490 500 550 560 570 580 590 600 pF1KE2 VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA CCDS54 ------------------------------------------------------------ 610 620 630 640 650 660 pF1KE2 HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR CCDS54 ------------------------------------------------------------ 670 680 690 700 710 720 pF1KE2 KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 -ELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV 510 520 530 540 550 560 730 740 750 760 770 780 pF1KE2 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS 570 580 590 600 610 620 790 800 810 820 830 840 pF1KE2 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK 630 640 650 660 670 680 850 860 870 880 890 900 pF1KE2 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD 690 700 710 720 730 740 910 920 930 940 950 960 pF1KE2 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC 750 760 770 780 790 800 970 980 990 1000 1010 1020 pF1KE2 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN 810 820 830 840 850 860 1030 1040 1050 1060 1070 1080 pF1KE2 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD 870 880 890 900 910 920 1090 1100 1110 1120 1130 1140 pF1KE2 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS 930 940 950 960 970 980 1150 1160 1170 1180 1190 1200 pF1KE2 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS 990 1000 1010 1020 1030 1040 1210 1220 1230 1240 1250 1260 pF1KE2 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD 1050 1060 1070 1080 1090 1100 1270 1280 1290 1300 1310 1320 pF1KE2 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS 1110 1120 1130 1140 1150 1160 1330 pF1KE2 NDYYISVYSVEKRVR ::::::::::::::: CCDS54 NDYYISVYSVEKRVR 1170 1335 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Jun 19 14:31:27 2019 done: Wed Jun 19 14:31:27 2019 Total Scan time: 2.510 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]