FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2322, 1335 aa 1>>>pF1KE2322 1335 - 1335 aa - 1335 aa Library: /omim/omim.rfq.tfa 65951994 residues in 93482 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3751+/-0.000436; mu= 13.9578+/- 0.027 mean_var=143.5082+/-29.598, 0's: 0 Z-trim(114.3): 41 B-trim: 0 in 0/55 Lambda= 0.107062 statistics sampled from 25125 (25166) to 25125 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.269), width: 16 Scan time: 8.170 The best scores are: opt bits E(93482) NP_065812 (OMIM: 607130) regulatory-associated pro (1335) 9008 1404.5 0 NP_001156506 (OMIM: 607130) regulatory-associated (1177) 4501 708.3 8.8e-203 >>NP_065812 (OMIM: 607130) regulatory-associated protein (1335 aa) initn: 9008 init1: 9008 opt: 9008 Z-score: 7523.8 bits: 1404.5 E(93482): 0 Smith-Waterman score: 9008; 100.0% identity (100.0% similar) in 1335 aa overlap (1-1335:1-1335) 10 20 30 40 50 60 pF1KE2 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS 1270 1280 1290 1300 1310 1320 1330 pF1KE2 NDYYISVYSVEKRVR ::::::::::::::: NP_065 NDYYISVYSVEKRVR 1330 >>NP_001156506 (OMIM: 607130) regulatory-associated prot (1177 aa) initn: 4501 init1: 4501 opt: 4501 Z-score: 3762.3 bits: 708.3 E(93482): 8.8e-203 Smith-Waterman score: 7599; 88.2% identity (88.2% similar) in 1335 aa overlap (1-1335:1-1177) 10 20 30 40 50 60 pF1KE2 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESEMLQSPLLGLGEEDEADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMGPQKALETIGANLQKQYENWQPRARYK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINPNHPLAQMPLPPSMKNC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVSLVPGVTLDLIEKIPG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NCTPVSSPRLPPTYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSPFFAEQLTAFQVWL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLL 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 QSSARELRPLLVFIWAKILAVDSSCQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILA ::::::::::::::::::::::: NP_001 QSSARELRPLLVFIWAKILAVDS------------------------------------- 490 500 550 560 570 580 590 600 pF1KE2 VIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSA NP_001 ------------------------------------------------------------ 610 620 630 640 650 660 pF1KE2 HEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERTDHSTTIDHNVAMMLAQLVSDGSPMVR NP_001 ------------------------------------------------------------ 670 680 690 700 710 720 pF1KE2 KELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -ELVVALSHLVVQYESNFCTVALQFIEEEKNYALPSPATTEGGSLTPVRDSPCTPRLRSV 510 520 530 540 550 560 730 740 750 760 770 780 pF1KE2 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILS 570 580 590 600 610 620 790 800 810 820 830 840 pF1KE2 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYK 630 640 650 660 670 680 850 860 870 880 890 900 pF1KE2 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAGGSPPASSTSSSSLTNDVAKQPVSRD 690 700 710 720 730 740 910 920 930 940 950 960 pF1KE2 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFC 750 760 770 780 790 800 970 980 990 1000 1010 1020 pF1KE2 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DWSARYFAQPVMKIPEEHDLESQIRKEREWRFLRNSRVRRQAQQVIQKGITRLDDQIFLN 810 820 830 840 850 860 1030 1040 1050 1060 1070 1080 pF1KE2 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RNPGVPSVVKFHPFTPCIAVADKDSICFWDWEKGEKLDYFHNGNPRYTRVTAMEYLNGQD 870 880 890 900 910 920 1090 1100 1110 1120 1130 1140 pF1KE2 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSLLLTATDDGAIRVWKNFADLEKNPEMVTAWQGLSDMLPTTRGAGMVVDWEQETGLLMS 930 940 950 960 970 980 1150 1160 1170 1180 1190 1200 pF1KE2 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGDVRIVRIWDTDREMKVQDIPTGADSCVTSLSCDSHRSLIVAGLGDGSIRVYDRRMALS 990 1000 1010 1020 1030 1040 1210 1220 1230 1240 1250 1260 pF1KE2 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ECRVMTYREHTAWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPESVNVLQIVKGLTALD 1050 1060 1070 1080 1090 1100 1270 1280 1290 1300 1310 1320 pF1KE2 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IHPQADLIACGSVNQFTAIYNSSGELINNIKYYDGFMGQRVGAISCLAFHPHWPHLAVGS 1110 1120 1130 1140 1150 1160 1330 pF1KE2 NDYYISVYSVEKRVR ::::::::::::::: NP_001 NDYYISVYSVEKRVR 1170 1335 residues in 1 query sequences 65951994 residues in 93482 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Wed Jun 19 14:31:27 2019 done: Wed Jun 19 14:31:29 2019 Total Scan time: 8.170 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]