FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2327, 979 aa 1>>>pF1KE2327 979 - 979 aa - 979 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.3440+/-0.00058; mu= 8.6720+/- 0.036 mean_var=266.9786+/-53.353, 0's: 0 Z-trim(115.3): 143 B-trim: 50 in 1/53 Lambda= 0.078494 statistics sampled from 25539 (25693) to 25539 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.301), width: 16 Scan time: 14.110 The best scores are: opt bits E(85289) NP_065916 (OMIM: 612767) ATP-dependent RNA helicas (1008) 4916 571.7 6.9e-162 NP_001107869 (OMIM: 612767) ATP-dependent RNA heli ( 994) 3463 407.1 2.3e-112 XP_016865224 (OMIM: 616530) PREDICTED: probable AT ( 971) 856 111.9 1.7e-23 NP_001332905 (OMIM: 616530) probable ATP-dependent (1130) 856 112.0 1.9e-23 XP_016865222 (OMIM: 616530) PREDICTED: probable AT (1139) 856 112.0 1.9e-23 XP_011541888 (OMIM: 616530) PREDICTED: probable AT (1162) 856 112.0 1.9e-23 NP_001332904 (OMIM: 616530) probable ATP-dependent (1268) 856 112.0 2e-23 XP_016865220 (OMIM: 616530) PREDICTED: probable AT (1277) 856 112.0 2e-23 XP_011541884 (OMIM: 616530) PREDICTED: probable AT (1406) 856 112.1 2.2e-23 NP_073739 (OMIM: 616530) probable ATP-dependent RN (1430) 856 112.1 2.2e-23 XP_016865219 (OMIM: 616530) PREDICTED: probable AT (1430) 856 112.1 2.2e-23 XP_011541883 (OMIM: 616530) PREDICTED: probable AT (1439) 856 112.1 2.2e-23 NP_001332894 (OMIM: 612720) ATP-dependent RNA heli ( 733) 842 110.2 4.2e-23 NP_001332893 (OMIM: 612720) ATP-dependent RNA heli (1318) 842 110.4 6.2e-23 NP_061903 (OMIM: 612720) ATP-dependent RNA helicas (1369) 842 110.5 6.4e-23 NP_001348 (OMIM: 603115) ATP-dependent RNA helicas (1270) 840 110.2 7.1e-23 NP_055781 (OMIM: 616423) putative ATP-dependent RN (1155) 734 98.1 2.7e-19 XP_016861406 (OMIM: 616423) PREDICTED: putative AT (1155) 734 98.1 2.7e-19 XP_016861405 (OMIM: 616423) PREDICTED: putative AT (1157) 734 98.1 2.8e-19 XP_006713096 (OMIM: 616423) PREDICTED: putative AT (1162) 734 98.2 2.8e-19 XP_016861404 (OMIM: 616423) PREDICTED: putative AT (1162) 734 98.2 2.8e-19 XP_011531800 (OMIM: 616423) PREDICTED: putative AT (1166) 734 98.2 2.8e-19 XP_011531799 (OMIM: 616423) PREDICTED: putative AT (1166) 734 98.2 2.8e-19 NP_001317919 (OMIM: 616423) putative ATP-dependent (1166) 734 98.2 2.8e-19 XP_011531798 (OMIM: 616423) PREDICTED: putative AT (1166) 734 98.2 2.8e-19 NP_619520 (OMIM: 616423) putative ATP-dependent RN (1194) 734 98.2 2.8e-19 XP_011531796 (OMIM: 616423) PREDICTED: putative AT (1194) 734 98.2 2.8e-19 XP_011531797 (OMIM: 616423) PREDICTED: putative AT (1194) 734 98.2 2.8e-19 XP_011531795 (OMIM: 616423) PREDICTED: putative AT (1228) 734 98.2 2.9e-19 XP_016861403 (OMIM: 616423) PREDICTED: putative AT (1238) 734 98.2 2.9e-19 XP_011531793 (OMIM: 616423) PREDICTED: putative AT (1265) 734 98.2 2.9e-19 XP_011531794 (OMIM: 616423) PREDICTED: putative AT (1265) 734 98.2 2.9e-19 XP_011531792 (OMIM: 616423) PREDICTED: putative AT (1265) 734 98.2 2.9e-19 XP_011525853 (OMIM: 615475) PREDICTED: probable AT (1143) 666 90.4 5.7e-17 XP_011525852 (OMIM: 615475) PREDICTED: probable AT (1143) 666 90.4 5.7e-17 XP_005259500 (OMIM: 615475) PREDICTED: probable AT (1143) 666 90.4 5.7e-17 NP_055496 (OMIM: 615475) probable ATP-dependent RN (1143) 666 90.4 5.7e-17 XP_011513243 (OMIM: 603405) PREDICTED: putative pr ( 524) 621 85.0 1.2e-15 XP_011513242 (OMIM: 603405) PREDICTED: putative pr ( 560) 621 85.0 1.2e-15 XP_011513241 (OMIM: 603405) PREDICTED: putative pr ( 742) 621 85.1 1.5e-15 XP_011513240 (OMIM: 603405) PREDICTED: putative pr ( 742) 621 85.1 1.5e-15 NP_001309145 (OMIM: 600396) ATP-dependent RNA heli ( 945) 622 85.4 1.6e-15 NP_001157711 (OMIM: 603405) putative pre-mRNA-spli ( 981) 621 85.3 1.8e-15 NP_001309146 (OMIM: 600396) ATP-dependent RNA heli (1129) 622 85.5 1.8e-15 NP_003578 (OMIM: 603405) putative pre-mRNA-splicin (1041) 621 85.3 1.8e-15 NP_001309150 (OMIM: 600396) ATP-dependent RNA heli (1218) 622 85.5 1.9e-15 NP_004932 (OMIM: 600396) ATP-dependent RNA helicas (1220) 622 85.5 1.9e-15 NP_001309149 (OMIM: 600396) ATP-dependent RNA heli (1152) 587 81.5 2.8e-14 NP_001309148 (OMIM: 600396) ATP-dependent RNA heli (1169) 587 81.5 2.8e-14 NP_001309147 (OMIM: 600396) ATP-dependent RNA heli (1179) 587 81.5 2.9e-14 >>NP_065916 (OMIM: 612767) ATP-dependent RNA helicase DH (1008 aa) initn: 4909 init1: 4909 opt: 4916 Z-score: 3027.4 bits: 571.7 E(85289): 6.9e-162 Smith-Waterman score: 6489; 96.9% identity (96.9% similar) in 1008 aa overlap (1-979:1-1008) 10 20 30 40 50 60 pF1KE2 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRCQFKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: NP_065 KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRT 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKANAKQRK :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: NP_065 PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT 670 680 690 700 710 720 730 740 750 pF1KE2 IAASLSFKDPFVIPLG-----------------------------WEEARRRGFRYEKDY :::::::::::::::: ::::::::::::::: NP_065 IAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDY 730 740 750 760 770 780 760 770 780 790 800 810 pF1KE2 CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY 790 800 810 820 830 840 820 830 840 850 860 870 pF1KE2 PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 850 860 870 880 890 900 880 890 900 910 920 930 pF1KE2 DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK 910 920 930 940 950 960 940 950 960 970 pF1KE2 IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS :::::::::::::::::::::::::::::::::::::::::::::::: NP_065 IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS 970 980 990 1000 >>NP_001107869 (OMIM: 612767) ATP-dependent RNA helicase (994 aa) initn: 5109 init1: 3463 opt: 3463 Z-score: 2138.2 bits: 407.1 E(85289): 2.3e-112 Smith-Waterman score: 6357; 95.5% identity (95.5% similar) in 1008 aa overlap (1-979:1-994) 10 20 30 40 50 60 pF1KE2 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSYDYHQNWGRDGGPRSSGGGYGGGPAGGHGGNRGSGGGGGGGGGGRGGRGRHPGHLKGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIGMWYAKKQGQKNKEAERQERAVVHMDERREEQIVQLLNSVQAKNDKESEAQISWFAPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DHGYGTEVSTKNTPCSENKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDGTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNSTGYQIRLQSRL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRKQGSILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRCQFKR ::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: NP_001 KVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQKEHRSQFKR 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVALIR 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQTQVFKRT :::::::::::::::::::::::::::::::::::: :::::::::: NP_001 YIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKS--------------VNQTQVFKRT 490 500 510 520 550 560 570 580 590 600 pF1KE2 PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKANAKQRK :::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::: NP_001 PPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKANAKQRK 530 540 550 560 570 580 610 620 630 640 650 660 pF1KE2 GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYFLSRLMD 590 600 610 620 630 640 670 680 690 700 710 720 pF1KE2 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLT 650 660 670 680 690 700 730 740 750 pF1KE2 IAASLSFKDPFVIPLG-----------------------------WEEARRRGFRYEKDY :::::::::::::::: ::::::::::::::: NP_001 IAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRRGFRYEKDY 710 720 730 740 750 760 760 770 780 790 800 810 pF1KE2 CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESNINSDNEKIIKAVICAGLY 770 780 790 800 810 820 820 830 840 850 860 870 pF1KE2 PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKVAKIRLNLGKKRKMVKVYTKTDGLVAVHPKSVNVEQTDFHYNWLIYHLKMRTSSIYLY 830 840 850 860 870 880 880 890 900 910 920 930 pF1KE2 DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELDILLQEK 890 900 910 920 930 940 940 950 960 970 pF1KE2 IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS 950 960 970 980 990 >>XP_016865224 (OMIM: 616530) PREDICTED: probable ATP-de (971 aa) initn: 960 init1: 463 opt: 856 Z-score: 542.8 bits: 111.9 E(85289): 1.7e-23 Smith-Waterman score: 1030; 34.9% identity (60.1% similar) in 571 aa overlap (448-941:121-678) 420 430 440 450 460 470 pF1KE2 FKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVA ::: . : : ..:.::::.::. XP_016 LESYSATLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHS-------FDDEKVDLDLIMH 100 110 120 130 140 480 490 500 510 520 530 pF1KE2 LIRYIVLEEEDGAILVFLPGWDNISTLHD-LLMSQVMF--KSDKFLIIPLHSLMPTVNQT :. : . ::.:.::::.:.: :.: .:... : .. .. .. ::: : : .: XP_016 LLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQK 150 160 170 180 190 200 540 550 560 570 580 590 pF1KE2 QVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKA .:.: : :::::...:::::::::..:::.:::.::.:: ::. : . .. :.::: XP_016 KVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKA 210 220 230 240 250 260 600 610 620 630 640 650 pF1KE2 NAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGG--IA .: :::::::: .:: :..:.. :: . . ..: ::.:: ::.::::. :.: . :: XP_016 SAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIA 270 280 290 300 310 320 660 670 680 690 700 710 pF1KE2 YFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALF :: . .:: : ... : ..:.: :.:: :: ::: ::::::.:::.: .... XP_016 DFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVL 330 340 350 360 370 380 720 730 740 pF1KE2 CCLDPVLTIAASLSFKDPFVIPL-------------------------------GWEEAR ::::.:::: .:...::::.: .:..:: XP_016 KCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKAR 390 400 410 420 430 440 750 760 770 780 790 800 pF1KE2 RRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES-NINSDNEK : .:. .: . :::. :.... .:. :. .: ..::: .:. : .. : ::.: XP_016 SDG--WERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWA 450 460 470 480 490 500 810 820 830 840 850 pF1KE2 IIKAVICAGLYPKVAKI-RLNL---GKKRKMVKVYTKTDGLVAVHPKSVNVEQTD----- ..::.. ::.::..... : :: : :.: :. . . : .:. .. .. XP_016 VVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPAS---VLSQPQYKKIPPANGQAAA 510 520 530 540 550 860 870 880 890 pF1KE2 ---FHYNWLIYHLKMRTSSIY-LYDCTEVSPYCLLFFGGDISIQKDNDQE---------- . .:::: :. : . :. :.: .: : : . .. :: XP_016 IKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIP 560 570 580 590 600 610 900 910 920 930 940 pF1KE2 -----------------TIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDW .. .:::. : . : :. .::.. :. .....: : XP_016 NDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSK-PW 620 630 640 650 660 670 950 960 970 pF1KE2 NDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS . XP_016 SQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADT 680 690 700 710 720 730 >>NP_001332905 (OMIM: 616530) probable ATP-dependent RNA (1130 aa) initn: 1164 init1: 463 opt: 856 Z-score: 542.0 bits: 112.0 E(85289): 1.9e-23 Smith-Waterman score: 1030; 34.9% identity (60.1% similar) in 571 aa overlap (448-941:289-846) 420 430 440 450 460 470 pF1KE2 FKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVA ::: . : : ..:.::::.::. NP_001 LESYSATLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHS-------FDDEKVDLDLIMH 260 270 280 290 300 310 480 490 500 510 520 530 pF1KE2 LIRYIVLEEEDGAILVFLPGWDNISTLHD-LLMSQVMF--KSDKFLIIPLHSLMPTVNQT :. : . ::.:.::::.:.: :.: .:... : .. .. .. ::: : : .: NP_001 LLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQK 320 330 340 350 360 370 540 550 560 570 580 590 pF1KE2 QVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKA .:.: : :::::...:::::::::..:::.:::.::.:: ::. : . .. :.::: NP_001 KVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKA 380 390 400 410 420 430 600 610 620 630 640 650 pF1KE2 NAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGG--IA .: :::::::: .:: :..:.. :: . . ..: ::.:: ::.::::. :.: . :: NP_001 SAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIA 440 450 460 470 480 490 660 670 680 690 700 710 pF1KE2 YFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALF :: . .:: : ... : ..:.: :.:: :: ::: ::::::.:::.: .... NP_001 DFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVL 500 510 520 530 540 550 720 730 740 pF1KE2 CCLDPVLTIAASLSFKDPFVIPL-------------------------------GWEEAR ::::.:::: .:...::::.: .:..:: NP_001 KCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKAR 560 570 580 590 600 610 750 760 770 780 790 800 pF1KE2 RRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES-NINSDNEK : .:. .: . :::. :.... .:. :. .: ..::: .:. : .. : ::.: NP_001 SDG--WERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWA 620 630 640 650 660 810 820 830 840 850 pF1KE2 IIKAVICAGLYPKVAKI-RLNL---GKKRKMVKVYTKTDGLVAVHPKSVNVEQTD----- ..::.. ::.::..... : :: : :.: :. . . : .:. .. .. NP_001 VVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPAS---VLSQPQYKKIPPANGQAAA 670 680 690 700 710 720 860 870 880 890 pF1KE2 ---FHYNWLIYHLKMRTSSIY-LYDCTEVSPYCLLFFGGDISIQKDNDQE---------- . .:::: :. : . :. :.: .: : : . .. :: NP_001 IKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIP 730 740 750 760 770 780 900 910 920 930 940 pF1KE2 -----------------TIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDW .. .:::. : . : :. .::.. :. .....: : NP_001 NDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSK-PW 790 800 810 820 830 840 950 960 970 pF1KE2 NDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS . NP_001 SQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADT 850 860 870 880 890 900 >>XP_016865222 (OMIM: 616530) PREDICTED: probable ATP-de (1139 aa) initn: 1164 init1: 463 opt: 856 Z-score: 542.0 bits: 112.0 E(85289): 1.9e-23 Smith-Waterman score: 1030; 34.9% identity (60.1% similar) in 571 aa overlap (448-941:289-846) 420 430 440 450 460 470 pF1KE2 FKRGFMQGHVNRQEKEEKEAIYKERWPDYVRELRRRYSASTVDVIEMMEDDKVDLNLIVA ::: . : : ..:.::::.::. XP_016 LESYSATLEFGNLDESSLVQTNGSDLSAEDRELLKAYHHS-------FDDEKVDLDLIMH 260 270 280 290 300 310 480 490 500 510 520 530 pF1KE2 LIRYIVLEEEDGAILVFLPGWDNISTLHD-LLMSQVMF--KSDKFLIIPLHSLMPTVNQT :. : . ::.:.::::.:.: :.: .:... : .. .. .. ::: : : .: XP_016 LLYNICHSCDAGAVLIFLPGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQK 320 330 340 350 360 370 540 550 560 570 580 590 pF1KE2 QVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKA .:.: : :::::...:::::::::..:::.:::.::.:: ::. : . .. :.::: XP_016 KVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKA 380 390 400 410 420 430 600 610 620 630 640 650 pF1KE2 NAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGG--IA .: :::::::: .:: :..:.. :: . . ..: ::.:: ::.::::. :.: . :: XP_016 SAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIA 440 450 460 470 480 490 660 670 680 690 700 710 pF1KE2 YFLSRLMDPPSNEAVLLSIRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALF :: . .:: : ... : ..:.: :.:: :: ::: ::::::.:::.: .... XP_016 DFLMKAPEPPPALIVRNAVQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVL 500 510 520 530 540 550 720 730 740 pF1KE2 CCLDPVLTIAASLSFKDPFVIPL-------------------------------GWEEAR ::::.:::: .:...::::.: .:..:: XP_016 KCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKAR 560 570 580 590 600 610 750 760 770 780 790 800 pF1KE2 RRGFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES-NINSDNEK : .:. .: . :::. :.... .:. :. .: ..::: .:. : .. : ::.: XP_016 SDG--WERAFCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWA 620 630 640 650 660 810 820 830 840 850 pF1KE2 IIKAVICAGLYPKVAKI-RLNL---GKKRKMVKVYTKTDGLVAVHPKSVNVEQTD----- ..::.. ::.::..... : :: : :.: :. . . : .:. .. .. XP_016 VVKAALVAGMYPNLVHVDRENLVLTGPKEKKVRFHPAS---VLSQPQYKKIPPANGQAAA 670 680 690 700 710 720 860 870 880 890 pF1KE2 ---FHYNWLIYHLKMRTSSIY-LYDCTEVSPYCLLFFGGDISIQKDNDQE---------- . .:::: :. : . :. :.: .: : : . .. :: XP_016 IKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIP 730 740 750 760 770 780 900 910 920 930 940 pF1KE2 -----------------TIAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDW .. .:::. : . : :. .::.. :. .....: : XP_016 NDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSK-PW 790 800 810 820 830 840 950 960 970 pF1KE2 NDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS . XP_016 SQVDEATIRAIIAVLSTEEQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADT 850 860 870 880 890 900 >>XP_011541888 (OMIM: 616530) PREDICTED: probable ATP-de (1162 aa) initn: 1532 init1: 463 opt: 856 Z-score: 541.9 bits: 112.0 E(85289): 1.9e-23 Smith-Waterman score: 1382; 33.6% identity (57.0% similar) in 902 aa overlap (199-897:185-1076) 170 180 190 200 210 220 pF1KE2 YLLQENEPDGTLDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVI :.. ::..:: . :.:.:..: ...:..: XP_011 AVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLI 160 170 180 190 200 210 230 240 250 260 270 280 pF1KE2 SGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGN :::: :::::. ::.::. .. .: ::: ::::::..::.::::::::: : : . XP_011 VGETGSGKTTQIPQFLLDDCFK--NGIPCRIFCTQPRRLAAIAVAERVAAERRERIG--Q 220 230 240 250 260 270 290 300 310 320 330 340 pF1KE2 STGYQIRLQSRLPRKQGSILYCTTGIILQWLQS-DPYLSSVSHIVLDEIHERNLQSDVLM . ::::::.::. : . .::.:..:. :.. : ::.:.:...::.:::. :: :. XP_011 TIGYQIRLESRVSPKT-LLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLL 280 290 300 310 320 350 360 370 380 390 400 pF1KE2 TVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVI----- : ..:::. . ::.:: ::.:... : .:::.::.:.: : : : :..:::.. XP_011 TKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGY 330 340 350 360 370 380 410 420 430 pF1KE2 ---EKIRYVPE-QKEHRCQF--------KRGFMQGHVNRQ-------------------- : ..: : :.:.. : ... .. . .:: XP_011 TNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAV 390 400 410 420 430 440 440 pF1KE2 -----EKE----------EKEAIYKERW---------------------PDY-------- ::. : .: .. : :: XP_011 FSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSAT 450 460 470 480 490 500 450 pF1KE2 ---------------------------------------------VRELRRRYSAS---- . .: . :::. XP_011 ALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSATLEFG 510 520 530 540 550 560 460 470 480 490 pF1KE2 ---------------TVDVIEMM-------EDDKVDLNLIVALIRYIVLEEEDGAILVFL ... :.. .:.::::.::. :. : . ::.:.:: XP_011 NLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFL 570 580 590 600 610 620 500 510 520 530 540 550 pF1KE2 PGWDNISTLHD-LLMSQVMF--KSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATN ::.:.: :.: .:... : .. .. .. ::: : : .: .:.: : :::::...:: XP_011 PGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTN 630 640 650 660 670 680 560 570 580 590 600 610 pF1KE2 IAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKANAKQRKGRAGRVQPGHCY :::::::..:::.:::.::.:: ::. : . .. :.:::.: :::::::: .:: :. XP_011 IAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICF 690 700 710 720 730 740 620 630 640 650 660 670 pF1KE2 HLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGG--IAYFLSRLMDPPSNEAVLLS .:.. :: . . ..: ::.:: ::.::::. :.: . :: :: . .:: : . XP_011 RLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNA 750 760 770 780 790 800 680 690 700 710 720 730 pF1KE2 IRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP .. : ..:.: :.:: :: ::: ::::::.:::.: .... ::::.:::: .:...:: XP_011 VQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDP 810 820 830 840 850 860 740 750 pF1KE2 FVIPL-------------------------------GWEEARRRGFRYEKDYCWEYFLSS ::.: .:..:: : .:. .: . :::. XP_011 FVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDG--WERAFCEKNFLSQ 870 880 890 900 910 920 760 770 780 790 800 810 pF1KE2 NTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES-NINSDNEKIIKAVICAGLYPKVAKI- :.... .:. :. .: ..::: .:. : .. : ::.: ..::.. ::.::..... XP_011 ATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVD 930 940 950 960 970 980 820 830 840 850 860 pF1KE2 RLNL---GKKRKMVKVYTKTDGLVAVHPKSVNVEQTD--------FHYNWLIYHLKMRTS : :: : :.: :. . . : .:. .. .. . .:::: :. XP_011 RENLVLTGPKEKKVRFHPAS---VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAH 990 1000 1010 1020 1030 1040 870 880 890 900 910 920 pF1KE2 SIY-LYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAHLVKELRKELD : . :. :.: .: : : . .. :: XP_011 RIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAA 1050 1060 1070 1080 1090 1100 930 940 950 960 970 pF1KE2 ILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQEKATPRNFPPRFQDGYYS XP_011 LKLDEWLHFTLEPEFSWGPHSFSSVLGFIPTEDLENLVVAHYLSKVIVLVCCCCYSNL 1110 1120 1130 1140 1150 1160 >>NP_001332904 (OMIM: 616530) probable ATP-dependent RNA (1268 aa) initn: 1492 init1: 463 opt: 856 Z-score: 541.4 bits: 112.0 E(85289): 2e-23 Smith-Waterman score: 1387; 32.3% identity (55.6% similar) in 973 aa overlap (199-941:23-984) 170 180 190 200 210 220 pF1KE2 YLLQENEPDGTLDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVI :.. ::..:: . :.:.:..: ...:..: NP_001 MSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLI 10 20 30 40 50 230 240 250 260 270 280 pF1KE2 SGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGN :::: :::::. ::.::. .. .: ::: ::::::..::.::::::::: : : . NP_001 VGETGSGKTTQIPQFLLDDCFK--NGIPCRIFCTQPRRLAAIAVAERVAAERRERIG--Q 60 70 80 90 100 290 300 310 320 330 340 pF1KE2 STGYQIRLQSRLPRKQGSILYCTTGIILQWLQS-DPYLSSVSHIVLDEIHERNLQSDVLM . ::::::.::. : . .::.:..:. :.. : ::.:.:...::.:::. :: :. NP_001 TIGYQIRLESRVSPKT-LLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLL 110 120 130 140 150 160 350 360 370 380 390 400 pF1KE2 TVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVI----- : ..:::. . ::.:: ::.:... : .:::.::.:.: : : : :..:::.. NP_001 TKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGY 170 180 190 200 210 220 410 420 430 pF1KE2 ---EKIRYVPE-QKEHRCQF--------KRGFMQGHVNRQ-------------------- : ..: : :.:.. : ... .. . .:: NP_001 TNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAV 230 240 250 260 270 280 440 pF1KE2 -----EKE----------EKEAIYKERW---------------------PDY-------- ::. : .: .. : :: NP_001 FSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSAT 290 300 310 320 330 340 450 pF1KE2 ---------------------------------------------VRELRRRYSAS---- . .: . :::. NP_001 ALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSATLEFG 350 360 370 380 390 400 460 470 480 490 pF1KE2 ---------------TVDVIEMM-------EDDKVDLNLIVALIRYIVLEEEDGAILVFL ... :.. .:.::::.::. :. : . ::.:.:: NP_001 NLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFL 410 420 430 440 450 460 500 510 520 530 540 550 pF1KE2 PGWDNISTLHD-LLMSQVMF--KSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATN ::.:.: :.: .:... : .. .. .. ::: : : .: .:.: : :::::...:: NP_001 PGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTN 470 480 490 500 510 520 560 570 580 590 600 610 pF1KE2 IAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKANAKQRKGRAGRVQPGHCY :::::::..:::.:::.::.:: ::. : . .. :.:::.: :::::::: .:: :. NP_001 IAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICF 530 540 550 560 570 580 620 630 640 650 660 670 pF1KE2 HLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGG--IAYFLSRLMDPPSNEAVLLS .:.. :: . . ..: ::.:: ::.::::. :.: . :: :: . .:: : . NP_001 RLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNA 590 600 610 620 630 640 680 690 700 710 720 730 pF1KE2 IRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP .. : ..:.: :.:: :: ::: ::::::.:::.: .... ::::.:::: .:...:: NP_001 VQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDP 650 660 670 680 690 700 740 750 pF1KE2 FVIPL-------------------------------GWEEARRRGFRYEKDYCWEYFLSS ::.: .:..:: : .:. .: . :::. NP_001 FVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDG--WERAFCEKNFLSQ 710 720 730 740 750 760 760 770 780 790 800 810 pF1KE2 NTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES-NINSDNEKIIKAVICAGLYPKVAKI- :.... .:. :. .: ..::: .:. : .. : ::.: ..::.. ::.::..... NP_001 ATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVD 770 780 790 800 810 820 820 830 840 850 860 pF1KE2 RLNL---GKKRKMVKVYTKTDGLVAVHPKSVNVEQTD--------FHYNWLIYHLKMRTS : :: : :.: :. . . : .:. .. .. . .:::: :. NP_001 RENLVLTGPKEKKVRFHPAS---VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAH 830 840 850 860 870 880 870 880 890 pF1KE2 SIY-LYDCTEVSPYCLLFFGGDISIQKDNDQE---------------------------T : . :. :.: .: : : . .. :: . NP_001 RIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAA 890 900 910 920 930 940 900 910 920 930 940 950 pF1KE2 IAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLI . .:::. : . : :. .::.. :. .....: :. NP_001 LKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSK-PWSQVDEATIRAIIAVLSTE 950 960 970 980 990 1000 960 970 pF1KE2 KTQEKATPRNFPPRFQDGYYS NP_001 EQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDECTTAERVLMKSPS 1010 1020 1030 1040 1050 1060 >>XP_016865220 (OMIM: 616530) PREDICTED: probable ATP-de (1277 aa) initn: 1492 init1: 463 opt: 856 Z-score: 541.4 bits: 112.0 E(85289): 2e-23 Smith-Waterman score: 1387; 32.3% identity (55.6% similar) in 973 aa overlap (199-941:23-984) 170 180 190 200 210 220 pF1KE2 YLLQENEPDGTLDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVI :.. ::..:: . :.:.:..: ...:..: XP_016 MSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLI 10 20 30 40 50 230 240 250 260 270 280 pF1KE2 SGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGN :::: :::::. ::.::. .. .: ::: ::::::..::.::::::::: : : . XP_016 VGETGSGKTTQIPQFLLDDCFK--NGIPCRIFCTQPRRLAAIAVAERVAAERRERIG--Q 60 70 80 90 100 290 300 310 320 330 340 pF1KE2 STGYQIRLQSRLPRKQGSILYCTTGIILQWLQS-DPYLSSVSHIVLDEIHERNLQSDVLM . ::::::.::. : . .::.:..:. :.. : ::.:.:...::.:::. :: :. XP_016 TIGYQIRLESRVSPKT-LLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLL 110 120 130 140 150 160 350 360 370 380 390 400 pF1KE2 TVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVI----- : ..:::. . ::.:: ::.:... : .:::.::.:.: : : : :..:::.. XP_016 TKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGY 170 180 190 200 210 220 410 420 430 pF1KE2 ---EKIRYVPE-QKEHRCQF--------KRGFMQGHVNRQ-------------------- : ..: : :.:.. : ... .. . .:: XP_016 TNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAV 230 240 250 260 270 280 440 pF1KE2 -----EKE----------EKEAIYKERW---------------------PDY-------- ::. : .: .. : :: XP_016 FSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSAT 290 300 310 320 330 340 450 pF1KE2 ---------------------------------------------VRELRRRYSAS---- . .: . :::. XP_016 ALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSATLEFG 350 360 370 380 390 400 460 470 480 490 pF1KE2 ---------------TVDVIEMM-------EDDKVDLNLIVALIRYIVLEEEDGAILVFL ... :.. .:.::::.::. :. : . ::.:.:: XP_016 NLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFL 410 420 430 440 450 460 500 510 520 530 540 550 pF1KE2 PGWDNISTLHD-LLMSQVMF--KSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATN ::.:.: :.: .:... : .. .. .. ::: : : .: .:.: : :::::...:: XP_016 PGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTN 470 480 490 500 510 520 560 570 580 590 600 610 pF1KE2 IAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKANAKQRKGRAGRVQPGHCY :::::::..:::.:::.::.:: ::. : . .. :.:::.: :::::::: .:: :. XP_016 IAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICF 530 540 550 560 570 580 620 630 640 650 660 670 pF1KE2 HLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGG--IAYFLSRLMDPPSNEAVLLS .:.. :: . . ..: ::.:: ::.::::. :.: . :: :: . .:: : . XP_016 RLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNA 590 600 610 620 630 640 680 690 700 710 720 730 pF1KE2 IRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP .. : ..:.: :.:: :: ::: ::::::.:::.: .... ::::.:::: .:...:: XP_016 VQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDP 650 660 670 680 690 700 740 750 pF1KE2 FVIPL-------------------------------GWEEARRRGFRYEKDYCWEYFLSS ::.: .:..:: : .:. .: . :::. XP_016 FVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDG--WERAFCEKNFLSQ 710 720 730 740 750 760 760 770 780 790 800 810 pF1KE2 NTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES-NINSDNEKIIKAVICAGLYPKVAKI- :.... .:. :. .: ..::: .:. : .. : ::.: ..::.. ::.::..... XP_016 ATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVD 770 780 790 800 810 820 820 830 840 850 860 pF1KE2 RLNL---GKKRKMVKVYTKTDGLVAVHPKSVNVEQTD--------FHYNWLIYHLKMRTS : :: : :.: :. . . : .:. .. .. . .:::: :. XP_016 RENLVLTGPKEKKVRFHPAS---VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAH 830 840 850 860 870 880 870 880 890 pF1KE2 SIY-LYDCTEVSPYCLLFFGGDISIQKDNDQE---------------------------T : . :. :.: .: : : . .. :: . XP_016 RIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAA 890 900 910 920 930 940 900 910 920 930 940 950 pF1KE2 IAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLI . .:::. : . : :. .::.. :. .....: :. XP_016 LKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSK-PWSQVDEATIRAIIAVLSTE 950 960 970 980 990 1000 960 970 pF1KE2 KTQEKATPRNFPPRFQDGYYS XP_016 EQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDECTTAERVLMKSPS 1010 1020 1030 1040 1050 1060 >>XP_011541884 (OMIM: 616530) PREDICTED: probable ATP-de (1406 aa) initn: 1532 init1: 463 opt: 856 Z-score: 540.9 bits: 112.1 E(85289): 2.2e-23 Smith-Waterman score: 1387; 32.3% identity (55.6% similar) in 973 aa overlap (199-941:185-1146) 170 180 190 200 210 220 pF1KE2 YLLQENEPDGTLDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVI :.. ::..:: . :.:.:..: ...:..: XP_011 AVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLI 160 170 180 190 200 210 230 240 250 260 270 280 pF1KE2 SGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGN :::: :::::. ::.::. .. .: ::: ::::::..::.::::::::: : : . XP_011 VGETGSGKTTQIPQFLLDDCFK--NGIPCRIFCTQPRRLAAIAVAERVAAERRERIG--Q 220 230 240 250 260 270 290 300 310 320 330 340 pF1KE2 STGYQIRLQSRLPRKQGSILYCTTGIILQWLQS-DPYLSSVSHIVLDEIHERNLQSDVLM . ::::::.::. : . .::.:..:. :.. : ::.:.:...::.:::. :: :. XP_011 TIGYQIRLESRVSPKT-LLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLL 280 290 300 310 320 350 360 370 380 390 400 pF1KE2 TVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVI----- : ..:::. . ::.:: ::.:... : .:::.::.:.: : : : :..:::.. XP_011 TKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGY 330 340 350 360 370 380 410 420 430 pF1KE2 ---EKIRYVPE-QKEHRCQF--------KRGFMQGHVNRQ-------------------- : ..: : :.:.. : ... .. . .:: XP_011 TNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAV 390 400 410 420 430 440 440 pF1KE2 -----EKE----------EKEAIYKERW---------------------PDY-------- ::. : .: .. : :: XP_011 FSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSAT 450 460 470 480 490 500 450 pF1KE2 ---------------------------------------------VRELRRRYSAS---- . .: . :::. XP_011 ALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSATLEFG 510 520 530 540 550 560 460 470 480 490 pF1KE2 ---------------TVDVIEMM-------EDDKVDLNLIVALIRYIVLEEEDGAILVFL ... :.. .:.::::.::. :. : . ::.:.:: XP_011 NLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFL 570 580 590 600 610 620 500 510 520 530 540 550 pF1KE2 PGWDNISTLHD-LLMSQVMF--KSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATN ::.:.: :.: .:... : .. .. .. ::: : : .: .:.: : :::::...:: XP_011 PGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTN 630 640 650 660 670 680 560 570 580 590 600 610 pF1KE2 IAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKANAKQRKGRAGRVQPGHCY :::::::..:::.:::.::.:: ::. : . .. :.:::.: :::::::: .:: :. XP_011 IAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICF 690 700 710 720 730 740 620 630 640 650 660 670 pF1KE2 HLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGG--IAYFLSRLMDPPSNEAVLLS .:.. :: . . ..: ::.:: ::.::::. :.: . :: :: . .:: : . XP_011 RLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNA 750 760 770 780 790 800 680 690 700 710 720 730 pF1KE2 IRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP .. : ..:.: :.:: :: ::: ::::::.:::.: .... ::::.:::: .:...:: XP_011 VQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDP 810 820 830 840 850 860 740 750 pF1KE2 FVIPL-------------------------------GWEEARRRGFRYEKDYCWEYFLSS ::.: .:..:: : .:. .: . :::. XP_011 FVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDG--WERAFCEKNFLSQ 870 880 890 900 910 920 760 770 780 790 800 810 pF1KE2 NTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES-NINSDNEKIIKAVICAGLYPKVAKI- :.... .:. :. .: ..::: .:. : .. : ::.: ..::.. ::.::..... XP_011 ATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVD 930 940 950 960 970 980 820 830 840 850 860 pF1KE2 RLNL---GKKRKMVKVYTKTDGLVAVHPKSVNVEQTD--------FHYNWLIYHLKMRTS : :: : :.: :. . . : .:. .. .. . .:::: :. XP_011 RENLVLTGPKEKKVRFHPAS---VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAH 990 1000 1010 1020 1030 1040 870 880 890 pF1KE2 SIY-LYDCTEVSPYCLLFFGGDISIQKDNDQE---------------------------T : . :. :.: .: : : . .. :: . XP_011 RIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAA 1050 1060 1070 1080 1090 1100 900 910 920 930 940 950 pF1KE2 IAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLI . .:::. : . : :. .::.. :. .....: :. XP_011 LKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSK-PWSQVDEATIRAIIAVLSTE 1110 1120 1130 1140 1150 1160 960 970 pF1KE2 KTQEKATPRNFPPRFQDGYYS XP_011 EQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDECTTAERVLMKSPS 1170 1180 1190 1200 1210 1220 >>NP_073739 (OMIM: 616530) probable ATP-dependent RNA he (1430 aa) initn: 1532 init1: 463 opt: 856 Z-score: 540.8 bits: 112.1 E(85289): 2.2e-23 Smith-Waterman score: 1387; 32.3% identity (55.6% similar) in 973 aa overlap (199-941:185-1146) 170 180 190 200 210 220 pF1KE2 YLLQENEPDGTLDQKLLEDLQKKKNDLRYIEMQHFREKLPSYGMQKELVNLIDNHQVTVI :.. ::..:: . :.:.:..: ...:..: NP_073 AVEAENREMSKTSGRLNNGIPQIPVKRGESEFDSFRQSLPVFEKQEEIVKIIKENKVVLI 160 170 180 190 200 210 230 240 250 260 270 280 pF1KE2 SGETGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGN :::: :::::. ::.::. .. .: ::: ::::::..::.::::::::: : : . NP_073 VGETGSGKTTQIPQFLLDDCFK--NGIPCRIFCTQPRRLAAIAVAERVAAERRERIG--Q 220 230 240 250 260 270 290 300 310 320 330 340 pF1KE2 STGYQIRLQSRLPRKQGSILYCTTGIILQWLQS-DPYLSSVSHIVLDEIHERNLQSDVLM . ::::::.::. : . .::.:..:. :.. : ::.:.:...::.:::. :: :. NP_073 TIGYQIRLESRVSPKT-LLTFCTNGVLLRTLMAGDSTLSTVTHVIVDEVHERDRFSDFLL 280 290 300 310 320 350 360 370 380 390 400 pF1KE2 TVVKDLLNFRSDLKVILMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVI----- : ..:::. . ::.:: ::.:... : .:::.::.:.: : : : :..:::.. NP_073 TKLRDLLQKHPTLKLILSSAALDVNLFIRYFGSCPVIYIQGRPFEVKEMFLEDILRTTGY 330 340 350 360 370 380 410 420 430 pF1KE2 ---EKIRYVPE-QKEHRCQF--------KRGFMQGHVNRQ-------------------- : ..: : :.:.. : ... .. . .:: NP_073 TNKEMLKYKKEKQQEEKQQTTLTEWYSAQENSFKPESQRQRTVLNVTDEYDLLDDGGDAV 390 400 410 420 430 440 440 pF1KE2 -----EKE----------EKEAIYKERW---------------------PDY-------- ::. : .: .. : :: NP_073 FSQLTEKDVNCLEPWLIKEMDACLSDIWLHKDIDAFAQVFHLILTENVSVDYRHSETSAT 450 460 470 480 490 500 450 pF1KE2 ---------------------------------------------VRELRRRYSAS---- . .: . :::. NP_073 ALMVAAGRGFASQVEQLISMGANVHSKASNGWMALDWAKHFGQTEIVDLLESYSATLEFG 510 520 530 540 550 560 460 470 480 490 pF1KE2 ---------------TVDVIEMM-------EDDKVDLNLIVALIRYIVLEEEDGAILVFL ... :.. .:.::::.::. :. : . ::.:.:: NP_073 NLDESSLVQTNGSDLSAEDRELLKAYHHSFDDEKVDLDLIMHLLYNICHSCDAGAVLIFL 570 580 590 600 610 620 500 510 520 530 540 550 pF1KE2 PGWDNISTLHD-LLMSQVMF--KSDKFLIIPLHSLMPTVNQTQVFKRTPPGVRKIVIATN ::.:.: :.: .:... : .. .. .. ::: : : .: .:.: : :::::...:: NP_073 PGYDEIVGLRDRILFDDKRFADSTHRYQVFMLHSNMQTSDQKKVLKNPPAGVRKIILSTN 630 640 650 660 670 680 560 570 580 590 600 610 pF1KE2 IAETSITIDDVVYVIDGGKIKETHFDTQNNNSTMSAEWVSKANAKQRKGRAGRVQPGHCY :::::::..:::.:::.::.:: ::. : . .. :.:::.: :::::::: .:: :. NP_073 IAETSITVNDVVFVIDSGKVKEKSFDALNFVTMLKMVWISKASAIQRKGRAGRCRPGICF 690 700 710 720 730 740 620 630 640 650 660 670 pF1KE2 HLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGG--IAYFLSRLMDPPSNEAVLLS .:.. :: . . ..: ::.:: ::.::::. :.: . :: :: . .:: : . NP_073 RLFSRLRFQNMLEFQTPELLRMPLQELCLHTKLLAPVNCPIADFLMKAPEPPPALIVRNA 750 760 770 780 790 800 680 690 700 710 720 730 pF1KE2 IRHLMELNALDKQEELTPLGVHLARLPVEPHIGKMILFGALFCCLDPVLTIAASLSFKDP .. : ..:.: :.:: :: ::: ::::::.:::.: .... ::::.:::: .:...:: NP_073 VQMLKTIDAMDTWEDLTELGYHLADLPVEPHLGKMVLCAVVLKCLDPILTIACTLAYRDP 810 820 830 840 850 860 740 750 pF1KE2 FVIPL-------------------------------GWEEARRRGFRYEKDYCWEYFLSS ::.: .:..:: : .:. .: . :::. NP_073 FVLPTQASQKRAAMLCRKRFTAGAFSDHMALLRAFQAWQKARSDG--WERAFCEKNFLSQ 870 880 890 900 910 920 760 770 780 790 800 810 pF1KE2 NTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPES-NINSDNEKIIKAVICAGLYPKVAKI- :.... .:. :. .: ..::: .:. : .. : ::.: ..::.. ::.::..... NP_073 ATMEIIIGMRTQLLGQLRASGFVRARGGGDIRDVNTNSENWAVVKAALVAGMYPNLVHVD 930 940 950 960 970 980 820 830 840 850 860 pF1KE2 RLNL---GKKRKMVKVYTKTDGLVAVHPKSVNVEQTD--------FHYNWLIYHLKMRTS : :: : :.: :. . . : .:. .. .. . .:::: :. NP_073 RENLVLTGPKEKKVRFHPAS---VLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAH 990 1000 1010 1020 1030 1040 870 880 890 pF1KE2 SIY-LYDCTEVSPYCLLFFGGDISIQKDNDQE---------------------------T : . :. :.: .: : : . .. :: . NP_073 RIANIRCCSAVTPVTILVFCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAA 1050 1060 1070 1080 1090 1100 900 910 920 930 940 950 pF1KE2 IAVDEWIVFQSPARIAHLVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLI . .:::. : . : :. .::.. :. .....: :. NP_073 LKLDEWLHFTLEPEAASLLLQLRQKWHSLFLRRMRAPSK-PWSQVDEATIRAIIAVLSTE 1110 1120 1130 1140 1150 1160 960 970 pF1KE2 KTQEKATPRNFPPRFQDGYYS NP_073 EQSAGLQQPSGIGQRPRPMSSEELPLASSWRSNNSRKSSADTEFSDECTTAERVLMKSPS 1170 1180 1190 1200 1210 1220 979 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 23:48:27 2016 done: Sun Nov 6 23:48:29 2016 Total Scan time: 14.110 Total Display time: 0.360 Function used was FASTA [36.3.4 Apr, 2011]