FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2328, 355 aa 1>>>pF1KE2328 355 - 355 aa - 355 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7561+/-0.000398; mu= 20.0491+/- 0.025 mean_var=73.4715+/-15.350, 0's: 0 Z-trim(111.3): 33 B-trim: 0 in 0/55 Lambda= 0.149629 statistics sampled from 19769 (19799) to 19769 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.605), E-opt: 0.2 (0.232), width: 16 Scan time: 7.280 The best scores are: opt bits E(85289) NP_478136 (OMIM: 606604) F-box only protein 32 iso ( 355) 2415 530.8 1.7e-150 NP_904356 (OMIM: 609098) F-box only protein 25 iso ( 358) 1544 342.8 6.8e-94 NP_680482 (OMIM: 606604) F-box only protein 32 iso ( 210) 1438 319.7 3.6e-87 XP_011533050 (OMIM: 609098) PREDICTED: F-box only ( 367) 1410 313.9 3.5e-85 XP_016868802 (OMIM: 609098) PREDICTED: F-box only ( 367) 1410 313.9 3.5e-85 NP_904357 (OMIM: 609098) F-box only protein 25 iso ( 367) 1410 313.9 3.5e-85 NP_036305 (OMIM: 609098) F-box only protein 25 iso ( 291) 1221 273.0 5.7e-73 XP_011533051 (OMIM: 609098) PREDICTED: F-box only ( 300) 1087 244.1 3e-64 NP_001229392 (OMIM: 606604) F-box only protein 32 ( 262) 990 223.1 5.5e-58 XP_016868803 (OMIM: 609098) PREDICTED: F-box only ( 336) 909 205.7 1.2e-52 XP_011528408 (OMIM: 260300,605648) PREDICTED: F-bo ( 366) 145 40.8 0.0056 NP_001244919 (OMIM: 260300,605648) F-box only prot ( 408) 145 40.9 0.0061 NP_001028196 (OMIM: 260300,605648) F-box only prot ( 443) 145 40.9 0.0065 NP_036311 (OMIM: 260300,605648) F-box only protein ( 522) 145 41.0 0.0072 >>NP_478136 (OMIM: 606604) F-box only protein 32 isoform (355 aa) initn: 2415 init1: 2415 opt: 2415 Z-score: 2822.9 bits: 530.8 E(85289): 1.7e-150 Smith-Waterman score: 2415; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355) 10 20 30 40 50 60 pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_478 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_478 AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 YVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_478 YVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 VQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_478 VQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_478 SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL 250 260 270 280 290 300 310 320 330 340 350 pF1KE2 VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_478 VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF 310 320 330 340 350 >>NP_904356 (OMIM: 609098) F-box only protein 25 isoform (358 aa) initn: 1545 init1: 1388 opt: 1544 Z-score: 1806.7 bits: 342.8 E(85289): 6.8e-94 Smith-Waterman score: 1544; 61.4% identity (83.6% similar) in 360 aa overlap (1-355:1-358) 10 20 30 40 50 pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKE---VYNKEN--LFNSL :::::::::::: .:.:: ::::: :. .. . .. :: . :.:. .::. NP_904 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNRCNISHSIILNSEDGEIFNNE 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD ... :.:::::: . . :.:: :..:::::::: :::::::::::::::::::::.:: : NP_904 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT :::::::.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : . NP_904 IRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN .:: :.. :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . : NP_904 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK :. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...:: NP_904 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE2 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF ::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .::: ::.:::: NP_904 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF 300 310 320 330 340 350 >>NP_680482 (OMIM: 606604) F-box only protein 32 isoform (210 aa) initn: 1438 init1: 1438 opt: 1438 Z-score: 1686.0 bits: 319.7 E(85289): 3.6e-87 Smith-Waterman score: 1438; 100.0% identity (100.0% similar) in 210 aa overlap (146-355:1-210) 120 130 140 150 160 170 pF1KE2 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT :::::::::::::::::::::::::::::: NP_680 MNILEKVVLKVLEDQQNIRLIRELLQTLYT 10 20 30 180 190 200 210 220 230 pF1KE2 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN 40 50 60 70 80 90 240 250 260 270 280 290 pF1KE2 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK 100 110 120 130 140 150 300 310 320 330 340 350 pF1KE2 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_680 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF 160 170 180 190 200 210 >>XP_011533050 (OMIM: 609098) PREDICTED: F-box only prot (367 aa) initn: 1411 init1: 1254 opt: 1410 Z-score: 1650.2 bits: 313.9 E(85289): 3.5e-85 Smith-Waterman score: 1516; 59.9% identity (81.6% similar) in 369 aa overlap (1-355:1-367) 10 20 30 40 50 pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKE---VYNKEN--LFNSL :::::::::::: .:.:: ::::: :. .. . .. :: . :.:. .::. XP_011 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNRCNISHSIILNSEDGEIFNNE 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD ... :.:::::: . . :.:: :..:::::::: :::::::::::::::::::::.:: : XP_011 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT :::::::.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : . XP_011 IRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN .:: :.. :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . : XP_011 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK :. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...:: XP_011 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL 240 250 260 270 280 290 300 310 320 330 340 pF1KE2 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKG---------TDHPCTANNPESCSVSLSP ::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .:: XP_011 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSP 300 310 320 330 340 350 350 pF1KE2 QDFINLFKF : ::.:::: XP_011 QHFIDLFKF 360 >>XP_016868802 (OMIM: 609098) PREDICTED: F-box only prot (367 aa) initn: 1411 init1: 1254 opt: 1410 Z-score: 1650.2 bits: 313.9 E(85289): 3.5e-85 Smith-Waterman score: 1516; 59.9% identity (81.6% similar) in 369 aa overlap (1-355:1-367) 10 20 30 40 50 pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKE---VYNKEN--LFNSL :::::::::::: .:.:: ::::: :. .. . .. :: . :.:. .::. XP_016 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNRCNISHSIILNSEDGEIFNNE 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD ... :.:::::: . . :.:: :..:::::::: :::::::::::::::::::::.:: : XP_016 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT :::::::.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : . XP_016 IRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN .:: :.. :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . : XP_016 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK :. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...:: XP_016 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL 240 250 260 270 280 290 300 310 320 330 340 pF1KE2 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKG---------TDHPCTANNPESCSVSLSP ::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .:: XP_016 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSP 300 310 320 330 340 350 350 pF1KE2 QDFINLFKF : ::.:::: XP_016 QHFIDLFKF 360 >>NP_904357 (OMIM: 609098) F-box only protein 25 isoform (367 aa) initn: 1411 init1: 1254 opt: 1410 Z-score: 1650.2 bits: 313.9 E(85289): 3.5e-85 Smith-Waterman score: 1516; 59.9% identity (81.6% similar) in 369 aa overlap (1-355:1-367) 10 20 30 40 50 pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKE---VYNKEN--LFNSL :::::::::::: .:.:: ::::: :. .. . .. :: . :.:. .::. NP_904 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNRCNISHSIILNSEDGEIFNNE 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD ... :.:::::: . . :.:: :..:::::::: :::::::::::::::::::::.:: : NP_904 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKERHGYCTLGEAFNRLDFSSAIQD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT :::::::.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : . NP_904 IRRFNYVVKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN .:: :.. :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . : NP_904 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK :. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...:: NP_904 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL 240 250 260 270 280 290 300 310 320 330 340 pF1KE2 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKG---------TDHPCTANNPESCSVSLSP ::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .:: NP_904 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSP 300 310 320 330 340 350 350 pF1KE2 QDFINLFKF : ::.:::: NP_904 QHFIDLFKF 360 >>NP_036305 (OMIM: 609098) F-box only protein 25 isoform (291 aa) initn: 1221 init1: 1221 opt: 1221 Z-score: 1431.0 bits: 273.0 E(85289): 5.7e-73 Smith-Waterman score: 1221; 65.0% identity (87.5% similar) in 263 aa overlap (93-355:29-291) 70 80 90 100 110 120 pF1KE2 KRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYV .:::::::::::::::::.:: : :::::: NP_036 MEKYSIMKSMNMHRKKGKRTILEMTQILKRHGYCTLGEAFNRLDFSSAIQDIRRFNYV 10 20 30 40 50 130 140 150 160 170 180 pF1KE2 VRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQ :.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : ..:: :.. NP_036 VKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIR 60 70 80 90 100 110 190 200 210 220 230 240 pF1KE2 RVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRLSD :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . ::. :.:: NP_036 GVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSD 120 130 140 150 160 170 250 260 270 280 290 300 pF1KE2 GRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKLVR : :...:::..: :..::::: ::::::::::.:.:. ..::::.::...:: ::: : . NP_036 GWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQK 180 190 200 210 220 230 310 320 330 340 350 pF1KE2 CYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF :: ::::::::..:.:: :: :: . ::::: .:.:: . .::: ::.:::: NP_036 HYPAKEQYGDTLHFCRHCSILFWKDSGHPCTAADPDSCFTPVSPQHFIDLFKF 240 250 260 270 280 290 >>XP_011533051 (OMIM: 609098) PREDICTED: F-box only prot (300 aa) initn: 1087 init1: 1087 opt: 1087 Z-score: 1274.5 bits: 244.1 E(85289): 3e-64 Smith-Waterman score: 1193; 62.9% identity (84.6% similar) in 272 aa overlap (93-355:29-300) 70 80 90 100 110 120 pF1KE2 KRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFNYV .:::::::::::::::::.:: : :::::: XP_011 MEKYSIMKSMNMHRKKGKRTILEMTQILKRHGYCTLGEAFNRLDFSSAIQDIRRFNYV 10 20 30 40 50 130 140 150 160 170 180 pF1KE2 VRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTLVQ :.::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : ..:: :.. XP_011 VKLLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSSTLCILIR 60 70 80 90 100 110 190 200 210 220 230 240 pF1KE2 RVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRLSD :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . ::. :.:: XP_011 GVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNNILYRFSD 120 130 140 150 160 170 250 260 270 280 290 300 pF1KE2 GRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKLVR : :...:::..: :..::::: ::::::::::.:.:. ..::::.::...:: ::: : . XP_011 GWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKLMYFALQK 180 190 200 210 220 230 310 320 330 340 350 pF1KE2 CYPRKEQYGDTLQLCKHCHILSWKG---------TDHPCTANNPESCSVSLSPQDFINLF :: ::::::::..:.:: :: :: . ::::: .:.:: . .::: ::.:: XP_011 HYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSPQHFIDLF 240 250 260 270 280 290 pF1KE2 KF :: XP_011 KF 300 >>NP_001229392 (OMIM: 606604) F-box only protein 32 isof (262 aa) initn: 990 init1: 990 opt: 990 Z-score: 1162.1 bits: 223.1 E(85289): 5.5e-58 Smith-Waterman score: 1640; 73.8% identity (73.8% similar) in 355 aa overlap (1-355:1-262) 10 20 30 40 50 60 pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKEVYNKENLFNSLNYDVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILDSRRFN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 YVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYTSLCTL :::: NP_001 YVVR-------------------------------------------------------- 190 200 210 220 230 240 pF1KE2 VQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLNIMQRL ::::::::::::::::::::::: NP_001 -------------------------------------PAFKGLTFTDLPLCLQLNIMQRL 130 140 250 260 270 280 290 300 pF1KE2 SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKKMYFKL 150 160 170 180 190 200 310 320 330 340 350 pF1KE2 VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VRCYPRKEQYGDTLQLCKHCHILSWKGTDHPCTANNPESCSVSLSPQDFINLFKF 210 220 230 240 250 260 >>XP_016868803 (OMIM: 609098) PREDICTED: F-box only prot (336 aa) initn: 1209 init1: 898 opt: 909 Z-score: 1066.2 bits: 205.7 E(85289): 1.2e-52 Smith-Waterman score: 1256; 52.6% identity (73.7% similar) in 369 aa overlap (1-355:1-336) 10 20 30 40 50 pF1KE2 MPFLGQDWRSPGQNWVKTADGWKRFLDEKSGSFVSDLSSYCNKE---VYNKEN--LFNSL :::::::::::: .:.:: ::::: :. .. . .. :: . :.:. .::. XP_016 MPFLGQDWRSPGWSWIKTEDGWKRC--ESCSQKLERENNRCNISHSIILNSEDGEIFNNE 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 NYDVAAKKRKKDMLNSKTKTQYFHQEKWIYVHKGSTKERHGYCTLGEAFNRLDFSTAILD ... :.:::::: . . :.:: :..:::::::: :::: XP_016 EHEYASKKRKKDHFRNDTNTQSFYREKWIYVHKESTKE---------------------- 60 70 80 90 120 130 140 150 160 170 pF1KE2 SRRFNYVVRLLELIAKSQLTSLSGIAQKNFMNILEKVVLKVLEDQQNIRLIRELLQTLYT ::.::::::::::::.::::..:::.:.: :::.:..: :::..::: : . XP_016 ---------LLQLIAKSQLTSLSGVAQKNYFNILDKIVQKVLDDHHNPRLIKDLLQDLSS 100 110 120 130 140 180 190 200 210 220 230 pF1KE2 SLCTLVQRVGKSVLVGNINMWVYRMETILHWQQQLNNIQITRPAFKGLTFTDLPLCLQLN .:: :.. :::::::::::.:. :.:::: :::::...:.:. . .:::..:::: . : XP_016 TLCILIRGVGKSVLVGNINIWICRLETILAWQQQLQDLQMTKQVNNGLTLSDLPLHMLNN 150 160 170 180 190 200 240 250 260 270 280 290 pF1KE2 IMQRLSDGRDLVSLGQAAPDLHVLSEDRLLWKKLCQYHFSERQIRKRLILSDKGQLDWKK :. :.::: :...:::..: :..::::: ::::::::::.:.:. ..::::.::...:: XP_016 ILYRFSDGWDIITLGQVTPTLYMLSEDRQLWKKLCQYHFAEKQFCRHLILSEKGHIEWKL 210 220 230 240 250 260 300 310 320 330 340 pF1KE2 MYFKLVRCYPRKEQYGDTLQLCKHCHILSWKG---------TDHPCTANNPESCSVSLSP ::: : . :: ::::::::..:.:: :: :: . ::::: .:.:: . .:: XP_016 MYFALQKHYPAKEQYGDTLHFCRHCSILFWKDYHLALLFKDSGHPCTAADPDSCFTPVSP 270 280 290 300 310 320 350 pF1KE2 QDFINLFKF : ::.:::: XP_016 QHFIDLFKF 330 355 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 15:53:37 2016 done: Sun Nov 6 15:53:38 2016 Total Scan time: 7.280 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]