FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2339, 290 aa
1>>>pF1KE2339 290 - 290 aa - 290 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0041+/-0.000366; mu= 16.7332+/- 0.023
mean_var=63.5557+/-12.869, 0's: 0 Z-trim(112.6): 56 B-trim: 0 in 0/58
Lambda= 0.160878
statistics sampled from 21488 (21544) to 21488 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.253), width: 16
Scan time: 6.140
The best scores are: opt bits E(85289)
NP_004083 (OMIM: 602292,616277) enoyl-CoA hydratas ( 290) 1893 448.1 9.4e-126
NP_001689 (OMIM: 250950,600529) methylglutaconyl-C ( 339) 450 113.2 7e-25
XP_005252123 (OMIM: 250950,600529) PREDICTED: meth ( 349) 445 112.0 1.6e-24
XP_011517104 (OMIM: 250950,600529) PREDICTED: meth ( 230) 416 105.2 1.2e-22
XP_016870339 (OMIM: 250950,600529) PREDICTED: meth ( 230) 416 105.2 1.2e-22
NP_001957 (OMIM: 607037,615605) peroxisomal bifunc ( 723) 379 96.9 1.2e-19
XP_016870338 (OMIM: 250950,600529) PREDICTED: meth ( 323) 367 93.9 4.3e-19
NP_001293119 (OMIM: 250950,600529) methylglutacony ( 310) 365 93.4 5.7e-19
XP_006717213 (OMIM: 250950,600529) PREDICTED: meth ( 320) 365 93.5 5.8e-19
XP_005252124 (OMIM: 250950,600529) PREDICTED: meth ( 333) 362 92.8 9.8e-19
XP_005252126 (OMIM: 250950,600529) PREDICTED: meth ( 298) 344 88.6 1.6e-17
XP_016870340 (OMIM: 250950,600529) PREDICTED: meth ( 214) 333 85.9 7.3e-17
NP_932164 (OMIM: 250620,610690) 3-hydroxyisobutyry ( 338) 335 86.5 7.6e-17
NP_055177 (OMIM: 250620,610690) 3-hydroxyisobutyry ( 386) 335 86.5 8.5e-17
XP_011509255 (OMIM: 250620,610690) PREDICTED: 3-hy ( 386) 335 86.5 8.5e-17
NP_000173 (OMIM: 600890,609015,609016) trifunction ( 763) 333 86.3 2e-16
NP_733841 (OMIM: 400016,415000) testis-specific ch ( 540) 316 82.2 2.4e-15
NP_004816 (OMIM: 400018,415000) testis-specific ch ( 541) 312 81.3 4.5e-15
NP_001137443 (OMIM: 603778) chromodomain Y-like pr ( 412) 303 79.1 1.5e-14
NP_001137442 (OMIM: 603778) chromodomain Y-like pr ( 412) 303 79.1 1.5e-14
XP_011513299 (OMIM: 603778) PREDICTED: chromodomai ( 522) 303 79.2 1.9e-14
NP_004815 (OMIM: 603778) chromodomain Y-like prote ( 544) 303 79.2 1.9e-14
NP_004671 (OMIM: 400016,415000) testis-specific ch ( 554) 297 77.8 5.1e-14
XP_016881937 (OMIM: 600696) PREDICTED: delta(3,5)- ( 248) 269 71.1 2.4e-12
NP_001389 (OMIM: 600696) delta(3,5)-Delta(2,4)-die ( 328) 269 71.2 3e-12
NP_001002030 (OMIM: 612136) ethylmalonyl-CoA decar ( 301) 267 70.7 3.9e-12
XP_005267105 (OMIM: 612136) PREDICTED: ethylmalony ( 301) 267 70.7 3.9e-12
XP_005267104 (OMIM: 612136) PREDICTED: ethylmalony ( 301) 267 70.7 3.9e-12
NP_001132982 (OMIM: 612136) ethylmalonyl-CoA decar ( 307) 267 70.7 4e-12
NP_001159482 (OMIM: 608024) enoyl-CoA delta isomer ( 364) 250 66.8 7e-11
NP_006108 (OMIM: 608024) enoyl-CoA delta isomerase ( 364) 250 66.8 7e-11
NP_996667 (OMIM: 608024) enoyl-CoA delta isomerase ( 394) 250 66.8 7.5e-11
XP_011529814 (OMIM: 400016,415000) PREDICTED: test ( 470) 249 66.6 1e-10
XP_011510819 (OMIM: 607037,615605) PREDICTED: pero ( 627) 235 63.5 1.2e-09
NP_001159887 (OMIM: 607037,615605) peroxisomal bif ( 627) 235 63.5 1.2e-09
XP_005252129 (OMIM: 250950,600529) PREDICTED: meth ( 255) 222 60.2 4.8e-09
XP_016866545 (OMIM: 612136) PREDICTED: ethylmalony ( 226) 219 59.5 7e-09
NP_001099014 (OMIM: 612136) ethylmalonyl-CoA decar ( 226) 219 59.5 7e-09
XP_011517102 (OMIM: 250950,600529) PREDICTED: meth ( 265) 217 59.0 1.1e-08
NP_001910 (OMIM: 600305) enoyl-CoA delta isomerase ( 302) 206 56.5 7.2e-08
XP_011534244 (OMIM: 612136) PREDICTED: ethylmalony ( 189) 188 52.2 8.9e-07
NP_001171500 (OMIM: 600305) enoyl-CoA delta isomer ( 285) 150 43.5 0.00056
XP_016865659 (OMIM: 608024) PREDICTED: enoyl-CoA d ( 334) 150 43.6 0.00064
XP_006715020 (OMIM: 608024) PREDICTED: enoyl-CoA d ( 364) 150 43.6 0.00068
>>NP_004083 (OMIM: 602292,616277) enoyl-CoA hydratase, m (290 aa)
initn: 1893 init1: 1893 opt: 1893 Z-score: 2378.7 bits: 448.1 E(85289): 9.4e-126
Smith-Waterman score: 1893; 100.0% identity (100.0% similar) in 290 aa overlap (1-290:1-290)
10 20 30 40 50 60
pF1KE2 MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 RAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMA
190 200 210 220 230 240
250 260 270 280 290
pF1KE2 KESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
250 260 270 280 290
>>NP_001689 (OMIM: 250950,600529) methylglutaconyl-CoA h (339 aa)
initn: 353 init1: 264 opt: 450 Z-score: 567.6 bits: 113.2 E(85289): 7e-25
Smith-Waterman score: 450; 32.2% identity (66.3% similar) in 255 aa overlap (43-290:85-339)
20 30 40 50 60 70
pF1KE2 GPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQA
.: . .. .:: . :.: .:: :..:
NP_001 VPAAGGPAPKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKA
60 70 80 90 100 110
80 90 100 110 120
pF1KE2 LKTFEEDPAVGAIVLTGG-DKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKP
. ... : : .:.. . : ::::.:: ..: .. . ::. . .... :
NP_001 VDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVP
120 130 140 150 160 170
130 140 150 160 170 180
pF1KE2 VIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAM
.:::..: :.::: :::. ::: :. .:... : .. :::.:::::: ::.: :::
NP_001 TIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAK
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE2 EMVLTGDRISAQDAKQAGLVSKICPV----ETLVEEAIQCAEKIASNSKIVVAMAKESVN
:..... .....:: .::.:.. .. ..:.. :... .. ... .:: ..:
NP_001 ELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAIN
240 250 260 270 280 290
250 260 270 280 290
pF1KE2 AAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
..:. :. : .:. . .:. : :: ::. :: ::: .: .
NP_001 QGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE
300 310 320 330
>>XP_005252123 (OMIM: 250950,600529) PREDICTED: methylgl (349 aa)
initn: 353 init1: 264 opt: 445 Z-score: 561.2 bits: 112.0 E(85289): 1.6e-24
Smith-Waterman score: 445; 32.5% identity (66.7% similar) in 249 aa overlap (49-290:101-349)
20 30 40 50 60 70
pF1KE2 VRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEE
.. .:: . :.: .:: :..:. ...
XP_005 MKTEDELRVRHLEEENRDSSSMAADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKS
80 90 100 110 120 130
80 90 100 110 120 130
pF1KE2 DPAVGAIVLTGG-DKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVN
: : .:.. . : ::::.:: ..: .. . ::. . .... :.:::..
XP_005 DKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAID
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE2 GYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTG
: :.::: :::. ::: :. .:... : .. :::.:::::: ::.: ::: :.....
XP_005 GLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA
200 210 220 230 240 250
200 210 220 230 240 250
pF1KE2 DRISAQDAKQAGLVSKICPV----ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMT
.....:: .::.:.. .. ..:.. :... .. ... .:: ..: ..:.
XP_005 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVD
260 270 280 290 300 310
260 270 280 290
pF1KE2 LTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
:. : .:. . .:. : :: ::. :: ::: .: .
XP_005 LVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRPPRYKGE
320 330 340
>>XP_011517104 (OMIM: 250950,600529) PREDICTED: methylgl (230 aa)
initn: 353 init1: 264 opt: 416 Z-score: 527.4 bits: 105.2 E(85289): 1.2e-22
Smith-Waterman score: 416; 32.8% identity (67.2% similar) in 229 aa overlap (69-290:2-230)
40 50 60 70 80 90
pF1KE2 EKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG-DKAFAAG
:..:. ... : : .:.. . : ::
XP_011 MLSKAVDALKSDKKVRTIIIRSEVPGIFCAG
10 20 30
100 110 120 130 140 150
pF1KE2 ADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG
::.:: ..: .. . ::. . .... :.:::..: :.::: :::. ::: :.
XP_011 ADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAA
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV
.:... : .. :::.:::::: ::.: ::: :..... .....:: .::.:..
XP_011 SSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQ
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE2 ----ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDD
.. ..:.. :... .. ... .:: ..: ..:. :. : .:. . .:. : :
XP_011 NQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKD
160 170 180 190 200 210
280 290
pF1KE2 RKEGMTAFVEKRKANFKDQ
: ::. :: ::: .: .
XP_011 RLEGLLAFKEKRPPRYKGE
220 230
>>XP_016870339 (OMIM: 250950,600529) PREDICTED: methylgl (230 aa)
initn: 353 init1: 264 opt: 416 Z-score: 527.4 bits: 105.2 E(85289): 1.2e-22
Smith-Waterman score: 416; 32.8% identity (67.2% similar) in 229 aa overlap (69-290:2-230)
40 50 60 70 80 90
pF1KE2 EKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG-DKAFAAG
:..:. ... : : .:.. . : ::
XP_016 MLSKAVDALKSDKKVRTIIIRSEVPGIFCAG
10 20 30
100 110 120 130 140 150
pF1KE2 ADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG
::.:: ..: .. . ::. . .... :.:::..: :.::: :::. ::: :.
XP_016 ADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAA
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE2 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV
.:... : .. :::.:::::: ::.: ::: :..... .....:: .::.:..
XP_016 SSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQ
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE2 ----ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDD
.. ..:.. :... .. ... .:: ..: ..:. :. : .:. . .:. : :
XP_016 NQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKD
160 170 180 190 200 210
280 290
pF1KE2 RKEGMTAFVEKRKANFKDQ
: ::. :: ::: .: .
XP_016 RLEGLLAFKEKRPPRYKGE
220 230
>>NP_001957 (OMIM: 607037,615605) peroxisomal bifunction (723 aa)
initn: 419 init1: 257 opt: 379 Z-score: 473.8 bits: 96.9 E(85289): 1.2e-19
Smith-Waterman score: 379; 35.1% identity (66.5% similar) in 194 aa overlap (37-230:1-189)
10 20 30 40 50 60
pF1KE2 LLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLI
.:: .:...::.: : .::. :.
NP_001 MAEYTRLHNALALIRLRNPP-VNAISTTLL
10 20
70 80 90 100 110 120
pF1KE2 DELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQV
.....:. : .. :::. :.. :.:::::. ..: .. . . :.. .
NP_001 RDIKEGLQKAVIDHTIKAIVICGAEGKFSAGADIR---GFSAPRTFGLTLGHVVDEIQRN
30 40 50 60 70 80
130 140 150 160 170 180
pF1KE2 KKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKS
.:::.::..:.::::: :::. : : .:: . ::. .: .::: ::: : : .:
NP_001 EKPVVAAIQGMAFGGGLELALGCHYRIAHAEAQVGLPEVTLGLLPGARGTQLLPRLTGVP
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE2 LAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNA
:.... .: :: :..: . :...:. . :::::. :....
NP_001 AALDLITSGRRILADEALKLGILDKVVNSDP-VEEAIRFAQRVSDQPLESRRLCNKPIQS
150 160 170 180 190 200
250 260 270 280 290
pF1KE2 AFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
NP_001 LPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQYPYEVGIKKEEELFLYLLQSGQA
210 220 230 240 250 260
>>XP_016870338 (OMIM: 250950,600529) PREDICTED: methylgl (323 aa)
initn: 361 init1: 264 opt: 367 Z-score: 463.8 bits: 93.9 E(85289): 4.3e-19
Smith-Waterman score: 392; 31.0% identity (62.7% similar) in 255 aa overlap (43-290:85-323)
20 30 40 50 60 70
pF1KE2 GPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQA
.: . .. .:: . :.: .:: :..:
XP_016 VPAAGGPAPKRGYSSEMKTEDELRVRHLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKA
60 70 80 90 100 110
80 90 100 110 120
pF1KE2 LKTFEEDPAVGAIVLTGG-DKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKP
. ... : : .:.. . : ::::.:: ..: .. . ::. . .... :
XP_016 VDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVP
120 130 140 150 160 170
130 140 150 160 170 180
pF1KE2 VIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAM
.:::..: :.::: :::. ::: :. .:... : .. :::.:::::: ::.: :::
XP_016 TIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAK
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE2 EMVLTGDRISAQDAKQAGLVSKICPV----ETLVEEAIQCAEKIASNSKIVVAMAKESVN
:..... .....:: .::.:.. .. ..:.. :... .. ... .:: ..:
XP_016 ELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAIN
240 250 260 270 280 290
250 260 270 280 290
pF1KE2 AAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
..: :. : :: ::. :: ::: .: .
XP_016 QGME----------------TIPTKDRLEGLLAFKEKRPPRYKGE
300 310 320
>>NP_001293119 (OMIM: 250950,600529) methylglutaconyl-Co (310 aa)
initn: 305 init1: 254 opt: 365 Z-score: 461.6 bits: 93.4 E(85289): 5.7e-19
Smith-Waterman score: 365; 36.1% identity (70.5% similar) in 166 aa overlap (129-290:145-310)
100 110 120 130 140 150
pF1KE2 DIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA
:.:::..: :.::: :::. ::: :. .:
NP_001 VDALKSDKKVRTIIIRSEVPGIFCAANLPVPTIAAIDGLALGGGLELALACDIRVAASSA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE2 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV---
... : .. :::.:::::: ::.: ::: :..... .....:: .::.:..
NP_001 KMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQE
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE2 -ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKE
.. ..:.. :... .. ... .:: ..: ..:. :. : .:. . .:. : :: :
NP_001 GDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE
240 250 260 270 280 290
280 290
pF1KE2 GMTAFVEKRKANFKDQ
:. :: ::: .: .
NP_001 GLLAFKEKRPPRYKGE
300 310
>>XP_006717213 (OMIM: 250950,600529) PREDICTED: methylgl (320 aa)
initn: 305 init1: 254 opt: 365 Z-score: 461.4 bits: 93.5 E(85289): 5.8e-19
Smith-Waterman score: 365; 36.1% identity (70.5% similar) in 166 aa overlap (129-290:155-320)
100 110 120 130 140 150
pF1KE2 DIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA
:.:::..: :.::: :::. ::: :. .:
XP_006 VDALKSDKKVRTIIIRSEVPGIFCAANLPVPTIAAIDGLALGGGLELALACDIRVAASSA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV---
... : .. :::.:::::: ::.: ::: :..... .....:: .::.:..
XP_006 KMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE2 -ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKE
.. ..:.. :... .. ... .:: ..: ..:. :. : .:. . .:. : :: :
XP_006 GDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTIPTKDRLE
250 260 270 280 290 300
280 290
pF1KE2 GMTAFVEKRKANFKDQ
:. :: ::: .: .
XP_006 GLLAFKEKRPPRYKGE
310 320
>>XP_005252124 (OMIM: 250950,600529) PREDICTED: methylgl (333 aa)
initn: 361 init1: 264 opt: 362 Z-score: 457.4 bits: 92.8 E(85289): 9.8e-19
Smith-Waterman score: 387; 31.3% identity (63.1% similar) in 249 aa overlap (49-290:101-333)
20 30 40 50 60 70
pF1KE2 VRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEE
.. .:: . :.: .:: :..:. ...
XP_005 MKTEDELRVRHLEEENRDSSSMAADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKS
80 90 100 110 120 130
80 90 100 110 120 130
pF1KE2 DPAVGAIVLTGG-DKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVN
: : .:.. . : ::::.:: ..: .. . ::. . .... :.:::..
XP_005 DKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAID
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE2 GYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTG
: :.::: :::. ::: :. .:... : .. :::.:::::: ::.: ::: :.....
XP_005 GLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA
200 210 220 230 240 250
200 210 220 230 240 250
pF1KE2 DRISAQDAKQAGLVSKICPV----ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMT
.....:: .::.:.. .. ..:.. :... .. ... .:: ..: ..:
XP_005 RVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGME--
260 270 280 290 300
260 270 280 290
pF1KE2 LTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
:. : :: ::. :: ::: .: .
XP_005 --------------TIPTKDRLEGLLAFKEKRPPRYKGE
310 320 330
290 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 15:17:27 2016 done: Sun Nov 6 15:17:28 2016
Total Scan time: 6.140 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]