Result of FASTA (omim) for
pF1KE2346
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2346, 2804 aa
1>>>pF1KE2346 2804 - 2804 aa - 2804 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.3216+/-0.000612; mu= -12.9119+/- 0.038
mean_var=409.4616+/-85.951, 0's: 0 Z-trim(116.1): 97 B-trim: 608 in 2/57
Lambda= 0.063382
statistics sampled from 26950 (27044) to 26950 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.317), width: 16
Scan time: 22.360
The best scores are: opt bits E(85289)
NP_597677 (OMIM: 122470,608667) nipped-B-like prot (2804) 18293 1689.6 0
NP_056199 (OMIM: 122470,608667) nipped-B-like prot (2697) 17529 1619.8 0
XP_005248337 (OMIM: 122470,608667) PREDICTED: nipp (2698) 17529 1619.8 0
XP_005248339 (OMIM: 122470,608667) PREDICTED: nipp (2584) 16568 1531.9 0
XP_011512317 (OMIM: 122470,608667) PREDICTED: nipp (2421) 15829 1464.3 0
XP_016864818 (OMIM: 122470,608667) PREDICTED: nipp (2649) 15829 1464.3 0
XP_006714530 (OMIM: 122470,608667) PREDICTED: nipp (2755) 15829 1464.3 0
XP_016864819 (OMIM: 122470,608667) PREDICTED: nipp (2265) 14715 1362.4 0
XP_016864820 (OMIM: 122470,608667) PREDICTED: nipp (2262) 11469 1065.6 0
XP_006714531 (OMIM: 122470,608667) PREDICTED: nipp (2738) 10835 1007.7 0
>>NP_597677 (OMIM: 122470,608667) nipped-B-like protein (2804 aa)
initn: 18293 init1: 18293 opt: 18293 Z-score: 9053.3 bits: 1689.6 E(85289): 0
Smith-Waterman score: 18293; 100.0% identity (100.0% similar) in 2804 aa overlap (1-2804:1-2804)
10 20 30 40 50 60
pF1KE2 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE2 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE2 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE2 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE2 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE2 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KE2 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQ
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KE2 MNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_597 MNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLV
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800
pF1KE2 PWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
::::::::::::::::::::::::::::::::::::::::::::
NP_597 PWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
2770 2780 2790 2800
>>NP_056199 (OMIM: 122470,608667) nipped-B-like protein (2697 aa)
initn: 17524 init1: 17524 opt: 17529 Z-score: 8676.0 bits: 1619.8 E(85289): 0
Smith-Waterman score: 17529; 99.8% identity (99.9% similar) in 2693 aa overlap (1-2692:1-2693)
10 20 30 40 50 60
pF1KE2 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE2 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE2 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE2 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE2 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE2 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690
pF1KE2 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSG-SLRRSKRNSDSTELAA
::::::::::::::::::::::::::::::::::::::::::: :::.: :
NP_056 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGVRRRRSQRISQRIT
2650 2660 2670 2680 2690
2700 2710 2720 2730 2740 2750
pF1KE2 QMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKL
>>XP_005248337 (OMIM: 122470,608667) PREDICTED: nipped-B (2698 aa)
initn: 17524 init1: 17524 opt: 17529 Z-score: 8676.0 bits: 1619.8 E(85289): 0
Smith-Waterman score: 17529; 99.8% identity (99.9% similar) in 2693 aa overlap (1-2692:1-2693)
10 20 30 40 50 60
pF1KE2 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE2 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE2 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KE2 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KE2 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KE2 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690
pF1KE2 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSG-SLRRSKRNSDSTELAA
::::::::::::::::::::::::::::::::::::::::::: :::.: :
XP_005 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGVRRRRSQRISQRITH
2650 2660 2670 2680 2690
2700 2710 2720 2730 2740 2750
pF1KE2 QMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKL
>>XP_005248339 (OMIM: 122470,608667) PREDICTED: nipped-B (2584 aa)
initn: 16568 init1: 16568 opt: 16568 Z-score: 8201.3 bits: 1531.9 E(85289): 0
Smith-Waterman score: 16568; 100.0% identity (100.0% similar) in 2547 aa overlap (258-2804:38-2584)
230 240 250 260 270 280
pF1KE2 SGNSANHHADNPRHGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGT
::::::::::::::::::::::::::::::
XP_005 LDTISILLRYTKKKTGKCRRIMLLNSNTLPDGDSSTMRNAASFPLRSPQPVCSPAGSEGT
10 20 30 40 50 60
290 300 310 320 330 340
pF1KE2 PKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKGSRPPLILQSQSLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDI
70 80 90 100 110 120
350 360 370 380 390 400
pF1KE2 ISSPSKDSTKLTLRLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISSPSKDSTKLTLRLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITP
130 140 150 160 170 180
410 420 430 440 450 460
pF1KE2 QDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDINRPLNAAQCLSQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYD
190 200 210 220 230 240
470 480 490 500 510 520
pF1KE2 EVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVELDALAEIERIERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQE
250 260 270 280 290 300
530 540 550 560 570 580
pF1KE2 TGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVG
310 320 330 340 350 360
590 600 610 620 630 640
pF1KE2 SLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQ
370 380 390 400 410 420
650 660 670 680 690 700
pF1KE2 TEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKG
430 440 450 460 470 480
710 720 730 740 750 760
pF1KE2 ESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRD
490 500 510 520 530 540
770 780 790 800 810 820
pF1KE2 SGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDR
550 560 570 580 590 600
830 840 850 860 870 880
pF1KE2 GESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQK
610 620 630 640 650 660
890 900 910 920 930 940
pF1KE2 SRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLG
670 680 690 700 710 720
950 960 970 980 990 1000
pF1KE2 GRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQK
730 740 750 760 770 780
1010 1020 1030 1040 1050 1060
pF1KE2 LSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCE
790 800 810 820 830 840
1070 1080 1090 1100 1110 1120
pF1KE2 RVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGD
850 860 870 880 890 900
1130 1140 1150 1160 1170 1180
pF1KE2 HRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPK
910 920 930 940 950 960
1190 1200 1210 1220 1230 1240
pF1KE2 LTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAK
970 980 990 1000 1010 1020
1250 1260 1270 1280 1290 1300
pF1KE2 IKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKS
1030 1040 1050 1060 1070 1080
1310 1320 1330 1340 1350 1360
pF1KE2 ADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLS
1090 1100 1110 1120 1130 1140
1370 1380 1390 1400 1410 1420
pF1KE2 SKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENV
1150 1160 1170 1180 1190 1200
1430 1440 1450 1460 1470 1480
pF1KE2 SELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYI
1210 1220 1230 1240 1250 1260
1490 1500 1510 1520 1530 1540
pF1KE2 QMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLK
1270 1280 1290 1300 1310 1320
1550 1560 1570 1580 1590 1600
pF1KE2 KCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRV
1330 1340 1350 1360 1370 1380
1610 1620 1630 1640 1650 1660
pF1KE2 ASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDP
1390 1400 1410 1420 1430 1440
1670 1680 1690 1700 1710 1720
pF1KE2 SLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFL
1450 1460 1470 1480 1490 1500
1730 1740 1750 1760 1770 1780
pF1KE2 RSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIA
1510 1520 1530 1540 1550 1560
1790 1800 1810 1820 1830 1840
pF1KE2 VRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAE
1570 1580 1590 1600 1610 1620
1850 1860 1870 1880 1890 1900
pF1KE2 QYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVN
1630 1640 1650 1660 1670 1680
1910 1920 1930 1940 1950 1960
pF1KE2 ETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPV
1690 1700 1710 1720 1730 1740
1970 1980 1990 2000 2010 2020
pF1KE2 KKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTM
1750 1760 1770 1780 1790 1800
2030 2040 2050 2060 2070 2080
pF1KE2 QPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQH
1810 1820 1830 1840 1850 1860
2090 2100 2110 2120 2130 2140
pF1KE2 CVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTV
1870 1880 1890 1900 1910 1920
2150 2160 2170 2180 2190 2200
pF1KE2 GALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLM
1930 1940 1950 1960 1970 1980
2210 2220 2230 2240 2250 2260
pF1KE2 FEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEM
1990 2000 2010 2020 2030 2040
2270 2280 2290 2300 2310 2320
pF1KE2 GDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMG
2050 2060 2070 2080 2090 2100
2330 2340 2350 2360 2370 2380
pF1KE2 TDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDES
2110 2120 2130 2140 2150 2160
2390 2400 2410 2420 2430 2440
pF1KE2 SSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPL
2170 2180 2190 2200 2210 2220
2450 2460 2470 2480 2490 2500
pF1KE2 FIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRV
2230 2240 2250 2260 2270 2280
2510 2520 2530 2540 2550 2560
pF1KE2 DSDSDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDSDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKY
2290 2300 2310 2320 2330 2340
2570 2580 2590 2600 2610 2620
pF1KE2 SPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEH
2350 2360 2370 2380 2390 2400
2630 2640 2650 2660 2670 2680
pF1KE2 LDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRR
2410 2420 2430 2440 2450 2460
2690 2700 2710 2720 2730 2740
pF1KE2 SKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGS
2470 2480 2490 2500 2510 2520
2750 2760 2770 2780 2790 2800
pF1KE2 WTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
2530 2540 2550 2560 2570 2580
>>XP_011512317 (OMIM: 122470,608667) PREDICTED: nipped-B (2421 aa)
initn: 15829 init1: 15829 opt: 15829 Z-score: 7836.6 bits: 1464.3 E(85289): 0
Smith-Waterman score: 15829; 100.0% identity (100.0% similar) in 2421 aa overlap (1-2421:1-2421)
10 20 30 40 50 60
pF1KE2 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE2 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE2 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
:::::::::::::::::::::
XP_011 GNRQHRRAFLISLLNLFDDTA
2410 2420
>>XP_016864818 (OMIM: 122470,608667) PREDICTED: nipped-B (2649 aa)
initn: 17191 init1: 15829 opt: 15829 Z-score: 7836.0 bits: 1464.3 E(85289): 0
Smith-Waterman score: 17102; 98.0% identity (98.0% similar) in 2693 aa overlap (1-2692:1-2644)
10 20 30 40 50 60
pF1KE2 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE2 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE2 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
:::::::::::::::::::::
XP_016 GNRQHRRAFLISLLNLFDDTA---------------------------------------
2410 2420
2470 2480 2490 2500 2510 2520
pF1KE2 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------SMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
2430 2440 2450 2460 2470
2530 2540 2550 2560 2570 2580
pF1KE2 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
2480 2490 2500 2510 2520 2530
2590 2600 2610 2620 2630 2640
pF1KE2 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
2540 2550 2560 2570 2580 2590
2650 2660 2670 2680 2690
pF1KE2 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSG-SLRRSKRNSDSTELAA
::::::::::::::::::::::::::::::::::::::::::: :::.: :
XP_016 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGVRRRRSQRISQRITH
2600 2610 2620 2630 2640
2700 2710 2720 2730 2740 2750
pF1KE2 QMNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKL
>>XP_006714530 (OMIM: 122470,608667) PREDICTED: nipped-B (2755 aa)
initn: 17960 init1: 15829 opt: 15829 Z-score: 7835.7 bits: 1464.3 E(85289): 0
Smith-Waterman score: 17866; 98.3% identity (98.3% similar) in 2804 aa overlap (1-2804:1-2755)
10 20 30 40 50 60
pF1KE2 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE2 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE2 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
:::::::::::::::::::::
XP_006 GNRQHRRAFLISLLNLFDDTA---------------------------------------
2410 2420
2470 2480 2490 2500 2510 2520
pF1KE2 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ----------SMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
2430 2440 2450 2460 2470
2530 2540 2550 2560 2570 2580
pF1KE2 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
2480 2490 2500 2510 2520 2530
2590 2600 2610 2620 2630 2640
pF1KE2 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
2540 2550 2560 2570 2580 2590
2650 2660 2670 2680 2690 2700
pF1KE2 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQ
2600 2610 2620 2630 2640 2650
2710 2720 2730 2740 2750 2760
pF1KE2 MNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLV
2660 2670 2680 2690 2700 2710
2770 2780 2790 2800
pF1KE2 PWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
2720 2730 2740 2750
>>XP_016864819 (OMIM: 122470,608667) PREDICTED: nipped-B (2265 aa)
initn: 14715 init1: 14715 opt: 14715 Z-score: 7286.5 bits: 1362.4 E(85289): 0
Smith-Waterman score: 14715; 100.0% identity (100.0% similar) in 2265 aa overlap (540-2804:1-2265)
510 520 530 540 550 560
pF1KE2 YPQEAGGATGGNRPASQETGSTGNGSRPALMVSIDLHQAGRVDSQASITQDSDSIKKPEE
::::::::::::::::::::::::::::::
XP_016 MVSIDLHQAGRVDSQASITQDSDSIKKPEE
10 20 30
570 580 590 600 610 620
pF1KE2 IKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKQCNDAPVSVLQEDIVGSLKSTPENHPETPKKKSDPELSKSEMKQSESRLAESKPNENR
40 50 60 70 80 90
630 640 650 660 670 680
pF1KE2 LVETKSSENKLETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVETKSSENKLETKVETQTEELKQNESRTTECKQNESTIVEPKQNENRLSDTKPNDNKQN
100 110 120 130 140 150
690 700 710 720 730 740
pF1KE2 NGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NGRSETTKSRPETPKQKGESRPETPKQKSDGHPETPKQKGDGRPETPKQKGESRPETPKQ
160 170 180 190 200 210
750 760 770 780 790 800
pF1KE2 KNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQRPDGRS
220 230 240 250 260 270
810 820 830 840 850 860
pF1KE2 VSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSSSRNEHGIKSDSSKTDKLERK
280 290 300 310 320 330
870 880 890 900 910 920
pF1KE2 HRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRHESGDSRERPSSGEQKSRPDSPRVKQGDSNKSRSDKLGFKSPTSKDDKRTEGNKSKVD
340 350 360 370 380 390
930 940 950 960 970 980
pF1KE2 TNKAHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNKAHPDNKAEFPSYLLGGRSGALKNFVIPKIKRDKDGNVTQETKKMEMKGEPKDKVEKI
400 410 420 430 440 450
990 1000 1010 1020 1030 1040
pF1KE2 GLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLVEDLNKGAKPVVVLQKLSLDDVQKLIKDREDKSRSSLKPIKNKPSKSNKGSIDQSVLK
460 470 480 490 500 510
1050 1060 1070 1080 1090 1100
pF1KE2 ELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPPELLAEIESTMPLCERVKMNKRKRSTVNEKPKYAEISSDEDNDSDEAFESSRKRHKK
520 530 540 550 560 570
1110 1120 1130 1140 1150 1160
pF1KE2 DDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDKAWEYEERDRRSSGDHRRSGHSHEGRRSSGGGRYRNRSPSDSDMEDYSPPPSLSEVA
580 590 600 610 620 630
1170 1180 1190 1200 1210 1220
pF1KE2 RKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKMKKKEKQKKRKAYEPKLTPEEMMDSSTFKRFTASIENILDNLEDMDFTAFGDDDEIPQ
640 650 660 670 680 690
1230 1240 1250 1260 1270 1280
pF1KE2 ELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELLLGKHQLNELGSESAKIKAMGIMDKLSTDKTVKVLNILEKNIQDGSKLSTLLNHNNDT
700 710 720 730 740 750
1290 1300 1310 1320 1330 1340
pF1KE2 EEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEERLWRDLIMERVTKSADACLTTINIMTSPNMPKAVYIEDVIERVIQYTKFHLQNTLY
760 770 780 790 800 810
1350 1360 1370 1380 1390 1400
pF1KE2 PQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQRVIVMLYNKVCDIVSSLSELLEIQLLTDT
820 830 840 850 860 870
1410 1420 1430 1440 1450 1460
pF1KE2 TILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TILQVSSMGITPFFVENVSELQLCAIKLVTAVFSRYEKHRQLILEEIFTSLARLPTSKRS
880 890 900 910 920 930
1470 1480 1490 1500 1510 1520
pF1KE2 LRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRNFRLNSSDMDGEPMYIQMVTALVLQLIQCVVHLPSSEKDSNAEEDSNKKIDQDVVITN
940 950 960 970 980 990
1530 1540 1550 1560 1570 1580
pF1KE2 SYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYETAMRTAQNFLSIFLKKCGSKQGEEDYRPLFENFVQDLLSTVNKPEWPAAELLLSLLG
1000 1010 1020 1030 1040 1050
1590 1600 1610 1620 1630 1640
pF1KE2 RLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLVHQFSNKSTEMALRVASLDYLGTVAARLRKDAVTSKMDQGSIERILKQVSGGEDEIQ
1060 1070 1080 1090 1100 1110
1650 1660 1670 1680 1690 1700
pF1KE2 QLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLQKALLDYLDENTETDPSLVFSRKFYIAQWFRDTTLETEKAMKSQKDEESSEGTHHAKE
1120 1130 1140 1150 1160 1170
1710 1720 1730 1740 1750 1760
pF1KE2 IETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IETTGQIMHRAENRKKFLRSIIKTTPSQFSTLKMNSDTVDYDDACLIVRYLASMRPFAQS
1180 1190 1200 1210 1220 1230
1770 1780 1790 1800 1810 1820
pF1KE2 FDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDIYLTQILRVLGENAIAVRTKAMKCLSEVVAVDPSILARLDMQRGVHGRLMDNSTSVRE
1240 1250 1260 1270 1280 1290
1830 1840 1850 1860 1870 1880
pF1KE2 AAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAVELLGRFVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDICIEQPTFPKITEMC
1300 1310 1320 1330 1340 1350
1890 1900 1910 1920 1930 1940
pF1KE2 VKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKMIRRVNDEEGIKKLVNETFQKLWFTPTPHNDKEAMTRKILNITDVVAACRDTGYDWFE
1360 1370 1380 1390 1400 1410
1950 1960 1970 1980 1990 2000
pF1KE2 QLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLQNLLKSEEDSSYKPVKKACTQLVDNLVEHILKYEESLADSDNKGVNSGRLVACITTL
1420 1430 1440 1450 1460 1470
2010 2020 2030 2040 2050 2060
pF1KE2 FLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLFSKIRPQLMVKHAMTMQPYLTTKCSTQNDFMVICNVAKILELVVPLMEHPSETFLATI
1480 1490 1500 1510 1520 1530
2070 2080 2090 2100 2110 2120
pF1KE2 EEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDLMKLIIKYGMTVVQHCVSCLGAVVNKVTQNFKFVWACFNRYYGAISKLKSQHQEDPN
1540 1550 1560 1570 1580 1590
2130 2140 2150 2160 2170 2180
pF1KE2 NTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTSLLTNKPALLRSLFTVGALCRHFDFDLEDFKGNSKVNIKDKVLELLMYFTKHSDEEVQ
1600 1610 1620 1630 1640 1650
2190 2200 2210 2220 2230 2240
pF1KE2 TKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKAIIGLGFAFIQHPSLMFEQEVKNLYNNILSDKNSSVNLKIQVLKNLQTYLQEEDTRMQ
1660 1670 1680 1690 1700 1710
2250 2260 2270 2280 2290 2300
pF1KE2 QADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QADRDWKKVAKQEDLKEMGDVSSGMSSSIMQLYLKQVLEAFFHTQSSVRHFALNVIALTL
1720 1730 1740 1750 1760 1770
2310 2320 2330 2340 2350 2360
pF1KE2 NQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQGLIHPVQCVPYLIAMGTDPEPAMRNKADQQLVEIDKKYAGFIHMKAVAGMKMSYQVQQ
1780 1790 1800 1810 1820 1830
2370 2380 2390 2400 2410 2420
pF1KE2 AINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTDVTMLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AINTCLKDPVRGFRQDESSSALCSHLYSMIRGNRQHRRAFLISLLNLFDDTAKTDVTMLL
1840 1850 1860 1870 1880 1890
2430 2440 2450 2460 2470 2480
pF1KE2 YIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKSSPSKENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIADNLACFPYQTQEEPLFIMHHIDITLSVSGSNLLQSFKESMVKDKRKERKSSPSKENE
1900 1910 1920 1930 1940 1950
2490 2500 2510 2520 2530 2540
pF1KE2 SSDSEEEVSRPRKSRKRVDSDSDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSDSEEEVSRPRKSRKRVDSDSDSDSEDDINSVMKCLPENSAPLIEFANVSQGILLLLML
1960 1970 1980 1990 2000 2010
2550 2560 2570 2580 2590 2600
pF1KE2 KQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KQHLKNLCGFSDSKIQKYSPSESAKVYDKAINRKTGVHFHPKQTLDFLRSDMANSKITEE
2020 2030 2040 2050 2060 2070
2610 2620 2630 2640 2650 2660
pF1KE2 VKRSIVKQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKRSIVKQYLDFKLLMEHLDPDEEEEEGEVSASTNARNKAITSLLGGGSPKNNTAAETED
2080 2090 2100 2110 2120 2130
2670 2680 2690 2700 2710 2720
pF1KE2 DESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DESDGEDRGGGTSGSLRRSKRNSDSTELAAQMNESVDVMDVIAICCPKYKDRPQIARVVQ
2140 2150 2160 2170 2180 2190
2730 2740 2750 2760 2770 2780
pF1KE2 KTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTSSGFSVQWMAGSYSGSWTEAKRRDGRKLVPWVDTIKESDIIYKKIALTSANKLTNKVV
2200 2210 2220 2230 2240 2250
2790 2800
pF1KE2 QTLRSLYAAKDGTSS
:::::::::::::::
XP_016 QTLRSLYAAKDGTSS
2260
>>XP_016864820 (OMIM: 122470,608667) PREDICTED: nipped-B (2262 aa)
initn: 11432 init1: 11432 opt: 11469 Z-score: 5682.3 bits: 1065.6 E(85289): 0
Smith-Waterman score: 13631; 80.7% identity (80.7% similar) in 2804 aa overlap (1-2804:1-2262)
10 20 30 40 50 60
pF1KE2 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
::::::::::::::::::
XP_016 ERESAIERERFSKEVQDK------------------------------------------
490
550 560 570 580 590 600
pF1KE2 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
XP_016 ------------------------------------------------------------
610 620 630 640 650 660
pF1KE2 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
XP_016 ------------------------------------------------------------
670 680 690 700 710 720
pF1KE2 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
XP_016 ------------------------------------------------------------
730 740 750 760 770 780
pF1KE2 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
XP_016 ------------------------------------------------------------
790 800 810 820 830 840
pF1KE2 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
XP_016 ------------------------------------------------------------
850 860 870 880 890 900
pF1KE2 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
XP_016 ------------------------------------------------------------
910 920 930 940 950 960
pF1KE2 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
XP_016 ------------------------------------------------------------
970 980 990 1000 1010 1020
pF1KE2 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
XP_016 ------------------------------------------------------------
1030 1040 1050 1060 1070 1080
pF1KE2 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
::::::::::::::::::::::::::::::::::::::::
XP_016 --------------------GSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
500 510 520 530
1090 1100 1110 1120 1130 1140
pF1KE2 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
540 550 560 570 580 590
1150 1160 1170 1180 1190 1200
pF1KE2 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
600 610 620 630 640 650
1210 1220 1230 1240 1250 1260
pF1KE2 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
660 670 680 690 700 710
1270 1280 1290 1300 1310 1320
pF1KE2 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
720 730 740 750 760 770
1330 1340 1350 1360 1370 1380
pF1KE2 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
780 790 800 810 820 830
1390 1400 1410 1420 1430 1440
pF1KE2 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
840 850 860 870 880 890
1450 1460 1470 1480 1490 1500
pF1KE2 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
900 910 920 930 940 950
1510 1520 1530 1540 1550 1560
pF1KE2 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
960 970 980 990 1000 1010
1570 1580 1590 1600 1610 1620
pF1KE2 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
1020 1030 1040 1050 1060 1070
1630 1640 1650 1660 1670 1680
pF1KE2 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
1080 1090 1100 1110 1120 1130
1690 1700 1710 1720 1730 1740
pF1KE2 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
1140 1150 1160 1170 1180 1190
1750 1760 1770 1780 1790 1800
pF1KE2 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
1200 1210 1220 1230 1240 1250
1810 1820 1830 1840 1850 1860
pF1KE2 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
1260 1270 1280 1290 1300 1310
1870 1880 1890 1900 1910 1920
pF1KE2 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
1320 1330 1340 1350 1360 1370
1930 1940 1950 1960 1970 1980
pF1KE2 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
1380 1390 1400 1410 1420 1430
1990 2000 2010 2020 2030 2040
pF1KE2 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
1440 1450 1460 1470 1480 1490
2050 2060 2070 2080 2090 2100
pF1KE2 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
1500 1510 1520 1530 1540 1550
2110 2120 2130 2140 2150 2160
pF1KE2 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
1560 1570 1580 1590 1600 1610
2170 2180 2190 2200 2210 2220
pF1KE2 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
1620 1630 1640 1650 1660 1670
2230 2240 2250 2260 2270 2280
pF1KE2 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
1680 1690 1700 1710 1720 1730
2290 2300 2310 2320 2330 2340
pF1KE2 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
1740 1750 1760 1770 1780 1790
2350 2360 2370 2380 2390 2400
pF1KE2 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
1800 1810 1820 1830 1840 1850
2410 2420 2430 2440 2450 2460
pF1KE2 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
1860 1870 1880 1890 1900 1910
2470 2480 2490 2500 2510 2520
pF1KE2 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
1920 1930 1940 1950 1960 1970
2530 2540 2550 2560 2570 2580
pF1KE2 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
1980 1990 2000 2010 2020 2030
2590 2600 2610 2620 2630 2640
pF1KE2 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
2040 2050 2060 2070 2080 2090
2650 2660 2670 2680 2690 2700
pF1KE2 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQ
2100 2110 2120 2130 2140 2150
2710 2720 2730 2740 2750 2760
pF1KE2 MNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLV
2160 2170 2180 2190 2200 2210
2770 2780 2790 2800
pF1KE2 PWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
2220 2230 2240 2250 2260
>>XP_006714531 (OMIM: 122470,608667) PREDICTED: nipped-B (2738 aa)
initn: 10564 init1: 10564 opt: 10835 Z-score: 5367.8 bits: 1007.7 E(85289): 0
Smith-Waterman score: 17676; 97.6% identity (97.6% similar) in 2804 aa overlap (1-2804:1-2738)
10 20 30 40 50 60
pF1KE2 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNGDMPHVPITTLAGIASLTDLLNQLPLPSPLPATTTKSLLFNARIAEEVNCLLACRDDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVSQLVHSLNQVSTDHIELKDNLGSDDPEGDIPVLLQAVLARSPNVFREKSMQNRYVQSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MMMSQYKLSQNSMHSSPASSNYQQTTISHSPSSRFVPPQTSSGNRFMPQQNSPVPSPYAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSPAGYMPYSHPSSYTTHPQMQQASVSSPIVAGGLRNIHDNKVSGPLSGNSANHHADNPR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HGSSEDYLHMVHRLSSDDGDSSTMRNAASFPLRSPQPVCSPAGSEGTPKGSRPPLILQSQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLPCSSPRDVPPDILLDSPERKQKKQKKMKLGKDEKEQSEKAAMYDIISSPSKDSTKLTL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLSRVRSSDMDQQEDMISGVENSNVSENDIPFNVQYPGQTSKTPITPQDINRPLNAAQCL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQQEQTAFLPANQVPVLQQNTSVAAKQPQTSVVQNQQQISQQGPIYDEVELDALAEIERI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ERESAIERERFSKEVQDKDKPLKKRKQDSYPQEAGGATGGNRPASQETGSTGNGSRPALM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSIDLHQAGRVDSQASITQDSDSIKKPEEIKQCNDAPVSVLQEDIVGSLKSTPENHPETP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKKSDPELSKSEMKQSESRLAESKPNENRLVETKSSENKLETKVETQTEELKQNESRTTE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CKQNESTIVEPKQNENRLSDTKPNDNKQNNGRSETTKSRPETPKQKGESRPETPKQKSDG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HPETPKQKGDGRPETPKQKGESRPETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KHKQDTKSDSPRLKSERAEALKQRPDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRPETLRSSSRNEHGIKSDSSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKSRSDKLGFKSPTSKDDKRTEGNKSKVDTNKAHPDNKAEFPSYLLGGRSGALKNFVIPK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKRDKDGNVTQETKKMEMKGEPKDKVEKIGLVEDLNKGAKPVVVLQKLSLDDVQKLIKDR
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EDKSRSSLKPIKNKPSKSNKGSIDQSVLKELPPELLAEIESTMPLCERVKMNKRKRSTVN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EKPKYAEISSDEDNDSDEAFESSRKRHKKDDDKAWEYEERDRRSSGDHRRSGHSHEGRRS
:::::::::::::::::::::
XP_006 EKPKYAEISSDEDNDSDEAFE---------------------------------------
1090 1100
1150 1160 1170 1180 1190 1200
pF1KE2 SGGGRYRNRSPSDSDMEDYSPPPSLSEVARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
::::::::::::::::::::::::::::::::
XP_006 ---------------------------FARKMKKKEKQKKRKAYEPKLTPEEMMDSSTFK
1110 1120 1130
1210 1220 1230 1240 1250 1260
pF1KE2 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RFTASIENILDNLEDMDFTAFGDDDEIPQELLLGKHQLNELGSESAKIKAMGIMDKLSTD
1140 1150 1160 1170 1180 1190
1270 1280 1290 1300 1310 1320
pF1KE2 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KTVKVLNILEKNIQDGSKLSTLLNHNNDTEEEERLWRDLIMERVTKSADACLTTINIMTS
1200 1210 1220 1230 1240 1250
1330 1340 1350 1360 1370 1380
pF1KE2 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNMPKAVYIEDVIERVIQYTKFHLQNTLYPQYDPVYRLDPHGGGLLSSKAKRAKCSTHKQ
1260 1270 1280 1290 1300 1310
1390 1400 1410 1420 1430 1440
pF1KE2 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVIVMLYNKVCDIVSSLSELLEIQLLTDTTILQVSSMGITPFFVENVSELQLCAIKLVTA
1320 1330 1340 1350 1360 1370
1450 1460 1470 1480 1490 1500
pF1KE2 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VFSRYEKHRQLILEEIFTSLARLPTSKRSLRNFRLNSSDMDGEPMYIQMVTALVLQLIQC
1380 1390 1400 1410 1420 1430
1510 1520 1530 1540 1550 1560
pF1KE2 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVHLPSSEKDSNAEEDSNKKIDQDVVITNSYETAMRTAQNFLSIFLKKCGSKQGEEDYRP
1440 1450 1460 1470 1480 1490
1570 1580 1590 1600 1610 1620
pF1KE2 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFENFVQDLLSTVNKPEWPAAELLLSLLGRLLVHQFSNKSTEMALRVASLDYLGTVAARL
1500 1510 1520 1530 1540 1550
1630 1640 1650 1660 1670 1680
pF1KE2 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKDAVTSKMDQGSIERILKQVSGGEDEIQQLQKALLDYLDENTETDPSLVFSRKFYIAQW
1560 1570 1580 1590 1600 1610
1690 1700 1710 1720 1730 1740
pF1KE2 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRDTTLETEKAMKSQKDEESSEGTHHAKEIETTGQIMHRAENRKKFLRSIIKTTPSQFST
1620 1630 1640 1650 1660 1670
1750 1760 1770 1780 1790 1800
pF1KE2 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKMNSDTVDYDDACLIVRYLASMRPFAQSFDIYLTQILRVLGENAIAVRTKAMKCLSEVV
1680 1690 1700 1710 1720 1730
1810 1820 1830 1840 1850 1860
pF1KE2 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AVDPSILARLDMQRGVHGRLMDNSTSVREAAVELLGRFVLCRPQLAEQYYDMLIERILDT
1740 1750 1760 1770 1780 1790
1870 1880 1890 1900 1910 1920
pF1KE2 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GISVRKRVIKILRDICIEQPTFPKITEMCVKMIRRVNDEEGIKKLVNETFQKLWFTPTPH
1800 1810 1820 1830 1840 1850
1930 1940 1950 1960 1970 1980
pF1KE2 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NDKEAMTRKILNITDVVAACRDTGYDWFEQLLQNLLKSEEDSSYKPVKKACTQLVDNLVE
1860 1870 1880 1890 1900 1910
1990 2000 2010 2020 2030 2040
pF1KE2 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HILKYEESLADSDNKGVNSGRLVACITTLFLFSKIRPQLMVKHAMTMQPYLTTKCSTQND
1920 1930 1940 1950 1960 1970
2050 2060 2070 2080 2090 2100
pF1KE2 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FMVICNVAKILELVVPLMEHPSETFLATIEEDLMKLIIKYGMTVVQHCVSCLGAVVNKVT
1980 1990 2000 2010 2020 2030
2110 2120 2130 2140 2150 2160
pF1KE2 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNFKFVWACFNRYYGAISKLKSQHQEDPNNTSLLTNKPALLRSLFTVGALCRHFDFDLED
2040 2050 2060 2070 2080 2090
2170 2180 2190 2200 2210 2220
pF1KE2 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FKGNSKVNIKDKVLELLMYFTKHSDEEVQTKAIIGLGFAFIQHPSLMFEQEVKNLYNNIL
2100 2110 2120 2130 2140 2150
2230 2240 2250 2260 2270 2280
pF1KE2 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDKNSSVNLKIQVLKNLQTYLQEEDTRMQQADRDWKKVAKQEDLKEMGDVSSGMSSSIMQ
2160 2170 2180 2190 2200 2210
2290 2300 2310 2320 2330 2340
pF1KE2 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LYLKQVLEAFFHTQSSVRHFALNVIALTLNQGLIHPVQCVPYLIAMGTDPEPAMRNKADQ
2220 2230 2240 2250 2260 2270
2350 2360 2370 2380 2390 2400
pF1KE2 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QLVEIDKKYAGFIHMKAVAGMKMSYQVQQAINTCLKDPVRGFRQDESSSALCSHLYSMIR
2280 2290 2300 2310 2320 2330
2410 2420 2430 2440 2450 2460
pF1KE2 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GNRQHRRAFLISLLNLFDDTAKTDVTMLLYIADNLACFPYQTQEEPLFIMHHIDITLSVS
2340 2350 2360 2370 2380 2390
2470 2480 2490 2500 2510 2520
pF1KE2 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSNLLQSFKESMVKDKRKERKSSPSKENESSDSEEEVSRPRKSRKRVDSDSDSDSEDDIN
2400 2410 2420 2430 2440 2450
2530 2540 2550 2560 2570 2580
pF1KE2 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVMKCLPENSAPLIEFANVSQGILLLLMLKQHLKNLCGFSDSKIQKYSPSESAKVYDKAI
2460 2470 2480 2490 2500 2510
2590 2600 2610 2620 2630 2640
pF1KE2 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NRKTGVHFHPKQTLDFLRSDMANSKITEEVKRSIVKQYLDFKLLMEHLDPDEEEEEGEVS
2520 2530 2540 2550 2560 2570
2650 2660 2670 2680 2690 2700
pF1KE2 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASTNARNKAITSLLGGGSPKNNTAAETEDDESDGEDRGGGTSGSLRRSKRNSDSTELAAQ
2580 2590 2600 2610 2620 2630
2710 2720 2730 2740 2750 2760
pF1KE2 MNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNESVDVMDVIAICCPKYKDRPQIARVVQKTSSGFSVQWMAGSYSGSWTEAKRRDGRKLV
2640 2650 2660 2670 2680 2690
2770 2780 2790 2800
pF1KE2 PWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWVDTIKESDIIYKKIALTSANKLTNKVVQTLRSLYAAKDGTSS
2700 2710 2720 2730
2804 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:15:47 2016 done: Sun Nov 6 17:15:51 2016
Total Scan time: 22.360 Total Display time: 2.800
Function used was FASTA [36.3.4 Apr, 2011]