FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2349, 314 aa
  1>>>pF1KE2349 314 - 314 aa - 314 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.2458+/-0.00067; mu= 8.4600+/- 0.041
 mean_var=124.8578+/-24.647, 0's: 0 Z-trim(115.1): 5  B-trim: 0 in 0/55
 Lambda= 0.114780
 statistics sampled from 15686 (15691) to 15686 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.482), width:  16
 Scan time:  3.180

The best scores are:                                      opt bits E(32554)
CCDS2769.1 TREX1 gene_id:11277|Hs108|chr3          ( 314) 2114 360.2 1.2e-99
CCDS43086.1 TREX1 gene_id:11277|Hs108|chr3         ( 369) 2114 360.3 1.3e-99
CCDS59451.1 TREX1 gene_id:11277|Hs108|chr3         ( 304) 2039 347.8 6.2e-96
CCDS35437.1 TREX2 gene_id:11219|Hs108|chrX         ( 236)  605 110.3 1.5e-24


>>CCDS2769.1 TREX1 gene_id:11277|Hs108|chr3               (314 aa)
 initn: 2114 init1: 2114 opt: 2114  Z-score: 1902.7  bits: 360.2 E(32554): 1.2e-99
Smith-Waterman score: 2114; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:1-314)

               10        20        30        40        50        60
pF1KE2 MGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 MGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 PRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 PRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 LVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 SIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 SIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASAR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 TKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 TKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLA
              250       260       270       280       290       300

              310    
pF1KE2 VATLYGLSLATPGE
       ::::::::::::::
CCDS27 VATLYGLSLATPGE
              310    

>>CCDS43086.1 TREX1 gene_id:11277|Hs108|chr3              (369 aa)
 initn: 2114 init1: 2114 opt: 2114  Z-score: 1901.7  bits: 360.3 E(32554): 1.3e-99
Smith-Waterman score: 2114; 100.0% identity (100.0% similar) in 314 aa overlap (1-314:56-369)

                                             10        20        30
pF1KE2                               MGSQALPPGPMQTLIFFDMEATGLPFSQPK
                                     ::::::::::::::::::::::::::::::
CCDS43 PLPPLRILTLGTHTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPK
          30        40        50        60        70        80     

               40        50        60        70        80        90
pF1KE2 VTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 VTELCLLAVHRCALESPPTSQGPPPTVPPPPRVVDKLSLCVAPGKACSPAASEITGLSTA
          90       100       110       120       130       140     

              100       110       120       130       140       150
pF1KE2 VLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 VLAAHGRQCFDDNLANLLLAFLRRQPQPWCLVAHNGDRYDFPLLQAELAMLGLTSALDGA
         150       160       170       180       190       200     

              160       170       180       190       200       210
pF1KE2 FCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 FCVDSITALKALERASSPSEHGPRKSYSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQW
         210       220       230       240       250       260     

              220       230       240       250       260       270
pF1KE2 RPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 RPQALLRWVDAHARPFGTIRPMYGVTASARTKPRPSAVTTTAHLATTRNTSPSLGESRGT
         270       280       290       300       310       320     

              280       290       300       310    
pF1KE2 KDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE
       ::::::::::::::::::::::::::::::::::::::::::::
CCDS43 KDLPPVKDPGALSREGLLAPLGLLAILTLAVATLYGLSLATPGE
         330       340       350       360         

>>CCDS59451.1 TREX1 gene_id:11277|Hs108|chr3              (304 aa)
 initn: 2039 init1: 2039 opt: 2039  Z-score: 1835.8  bits: 347.8 E(32554): 6.2e-96
Smith-Waterman score: 2039; 100.0% identity (100.0% similar) in 304 aa overlap (11-314:1-304)

               10        20        30        40        50        60
pF1KE2 MGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPP
                 ::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59           MQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPP
                         10        20        30        40        50

               70        80        90       100       110       120
pF1KE2 PRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 PRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWC
               60        70        80        90       100       110

              130       140       150       160       170       180
pF1KE2 LVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 LVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPRKSYSLG
              120       130       140       150       160       170

              190       200       210       220       230       240
pF1KE2 SIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 SIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVTASAR
              180       190       200       210       220       230

              250       260       270       280       290       300
pF1KE2 TKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 TKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAILTLA
              240       250       260       270       280       290

              310    
pF1KE2 VATLYGLSLATPGE
       ::::::::::::::
CCDS59 VATLYGLSLATPGE
              300    

>>CCDS35437.1 TREX2 gene_id:11219|Hs108|chrX              (236 aa)
 initn: 412 init1: 412 opt: 605  Z-score: 554.1  bits: 110.3 E(32554): 1.5e-24
Smith-Waterman score: 605; 46.5% identity (66.8% similar) in 226 aa overlap (12-233:8-226)

               10        20        30        40        50        60
pF1KE2 MGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALESPPTSQGPPPTVPPP
                  .:..:.:.::::::  .:...:: :.:::: .::.:  ...   ..:  
CCDS35     MSEAPRAETFVFLDLEATGLPSVEPEIAELSLFAVHRSSLENPEHDESGALVLP--
                   10        20        30        40        50      

               70        80        90       100       110       120
pF1KE2 PRVVDKLSLCVAPGKACSPAASEITGLSTAVLAAHGRQCFDDNLANLLLAFLRRQPQPWC
        ::.:::.::. : .  .  ::::::::.  ::   .  ::  ..  : ::: ::  : :
CCDS35 -RVLDKLTLCMCPERPFTAKASEITGLSSEGLARCRKAGFDGAVVRTLQAFLSRQAGPIC
            60        70        80        90       100       110   

              130       140       150       160       170          
pF1KE2 LVAHNGDRYDFPLLQAELAMLGLTSALDGAFCVDSITALKALERASSPSEHGPR----KS
       ::::::  :::::: :::  ::     : . :.:.. ::..:.:: :   :: :    ..
CCDS35 LVAHNGFDYDFPLLCAELRRLGARLPRD-TVCLDTLPALRGLDRAHS---HGTRARGRQG
           120       130       140        150          160         

        180       190       200       210       220       230      
pF1KE2 YSLGSIYTRLYGQSPPDSHTAEGDVLALLSICQWRPQALLRWVDAHARPFGTIRPMYGVT
       :::::.. : .   :  .:.::::: .:: :   :   :: :.: .:: .. :.:::   
CCDS35 YSLGSLFHRYFRAEPSAAHSAEGDVHTLLLIFLHRAAELLAWADEQARGWAHIEPMYLPP
     170       180       190       200       210       220         

        240       250       260       270       280       290      
pF1KE2 ASARTKPRPSAVTTTAHLATTRNTSPSLGESRGTKDLPPVKDPGALSREGLLAPLGLLAI
                                                                   
CCDS35 DDPSLEA                                                     
     230                                                           




314 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 17:48:53 2016 done: Sun Nov  6 17:48:54 2016
 Total Scan time:  3.180 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]