FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2354, 3224 aa 1>>>pF1KE2354 3224 - 3224 aa - 3224 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2253+/-0.00132; mu= 13.2281+/- 0.080 mean_var=164.3644+/-32.784, 0's: 0 Z-trim(105.5): 77 B-trim: 82 in 1/50 Lambda= 0.100039 statistics sampled from 8379 (8450) to 8379 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.26), width: 16 Scan time: 7.900 The best scores are: opt bits E(32554) CCDS2079.1 RANBP2 gene_id:5903|Hs108|chr2 (3224) 21603 3132.5 0 CCDS42729.1 RGPD6 gene_id:729540|Hs108|chr2 ( 904) 5506 808.9 0 CCDS2083.1 RGPD5 gene_id:84220|Hs108|chr2 ( 904) 5506 808.9 0 CCDS46358.2 RGPD1 gene_id:400966|Hs108|chr2 (1748) 4656 686.4 4.3e-196 CCDS42710.2 RGPD2 gene_id:729857|Hs108|chr2 (1756) 4647 685.1 1.1e-195 CCDS46381.1 RGPD4 gene_id:285190|Hs108|chr2 (1758) 4643 684.5 1.6e-195 CCDS46379.1 RGPD3 gene_id:653489|Hs108|chr2 (1758) 4630 682.7 5.8e-195 CCDS46388.1 RGPD6 gene_id:729540|Hs108|chr2 (1765) 4624 681.8 1.1e-194 CCDS2082.1 RGPD5 gene_id:84220|Hs108|chr2 (1765) 4624 681.8 1.1e-194 CCDS46394.1 RGPD8 gene_id:727851|Hs108|chr2 (1765) 4606 679.2 6.4e-194 CCDS5494.1 PPIA gene_id:5478|Hs108|chr7 ( 165) 773 125.4 3.1e-28 CCDS7358.1 PPIF gene_id:10105|Hs108|chr10 ( 207) 770 125.0 5e-28 CCDS443.1 PPIE gene_id:10450|Hs108|chr1 ( 301) 686 113.0 3.1e-24 CCDS72898.1 PPIAL4C gene_id:653598|Hs108|chr1 ( 164) 662 109.4 2.1e-23 CCDS76197.1 PPIAL4A gene_id:653505|Hs108|chr1 ( 164) 659 108.9 2.8e-23 CCDS76201.1 PPIAL4E gene_id:730262|Hs108|chr1 ( 164) 653 108.1 5e-23 CCDS76202.1 PPIAL4F gene_id:728945|Hs108|chr1 ( 164) 653 108.1 5e-23 CCDS41375.2 PPIAL4G gene_id:644591|Hs108|chr1 ( 164) 651 107.8 6.2e-23 CCDS59199.1 PPIAL4D gene_id:645142|Hs108|chr1 ( 164) 650 107.6 6.8e-23 CCDS53299.1 PPIE gene_id:10450|Hs108|chr1 ( 314) 647 107.4 1.6e-22 CCDS442.1 PPIE gene_id:10450|Hs108|chr1 ( 296) 639 106.2 3.3e-22 CCDS74823.1 RANBP1 gene_id:5902|Hs108|chr22 ( 278) 608 101.7 7e-21 CCDS63408.1 RANBP1 gene_id:5902|Hs108|chr22 ( 200) 601 100.6 1.1e-20 CCDS3801.1 PPID gene_id:5481|Hs108|chr4 ( 370) 605 101.4 1.2e-20 CCDS13775.1 RANBP1 gene_id:5902|Hs108|chr22 ( 201) 598 100.2 1.5e-20 CCDS10191.1 PPIB gene_id:5479|Hs108|chr15 ( 216) 589 98.9 3.8e-20 CCDS469.1 PPIH gene_id:10465|Hs108|chr1 ( 177) 572 96.4 1.8e-19 CCDS4133.1 PPIC gene_id:5480|Hs108|chr5 ( 212) 546 92.7 2.8e-18 CCDS2235.1 PPIG gene_id:9360|Hs108|chr2 ( 754) 544 92.7 9.6e-18 CCDS75407.1 NUP153 gene_id:9972|Hs108|chr6 (1433) 538 92.0 3e-17 CCDS4541.1 NUP153 gene_id:9972|Hs108|chr6 (1475) 538 92.0 3e-17 CCDS64359.1 NUP153 gene_id:9972|Hs108|chr6 (1506) 538 92.0 3.1e-17 CCDS2702.1 NKTR gene_id:4820|Hs108|chr3 (1462) 514 88.6 3.3e-16 CCDS75592.1 PPIA gene_id:5478|Hs108|chr7 ( 105) 469 81.4 3.4e-15 CCDS69169.1 PPIL6 gene_id:285755|Hs108|chr6 ( 279) 476 82.7 3.8e-15 CCDS5074.1 PPIL6 gene_id:285755|Hs108|chr6 ( 311) 476 82.7 4.2e-15 CCDS81308.1 PPIH gene_id:10465|Hs108|chr1 ( 134) 393 70.5 8.4e-12 >>CCDS2079.1 RANBP2 gene_id:5903|Hs108|chr2 (3224 aa) initn: 21603 init1: 21603 opt: 21603 Z-score: 16848.8 bits: 3132.5 E(32554): 0 Smith-Waterman score: 21603; 100.0% identity (100.0% similar) in 3224 aa overlap (1-3224:1-3224) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKSLGGNDELSATFLEMKGHFYMHAGSLLLKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 NLMLLTLSTRDVQESRELLQSFDSALQSVKSLGGNDELSATFLEMKGHFYMHAGSLLLKM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 GQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 GQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLLN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 LSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 LSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDLT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 RYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 RYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESIC 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 ILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 ILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLIH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 RKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 RKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYIG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 RSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 RSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDAV 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 NGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 NGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLIK 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 IIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 IIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHSTP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 SPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 SPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPHR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 WPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 WPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 PVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGDD 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 YFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 YFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSLP 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 TQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 TQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGDG 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 YSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 YSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGKS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 VFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 VFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRAK 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 LFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 LFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAGS 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 DRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 DRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 RIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 RIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLNP 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 SNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 SNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQN 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 TKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 TKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKCA 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 ACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEANA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 ACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEANA 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 TRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 TRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 SATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 SATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEAS 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE2 ATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 ATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSLK 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE2 CVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 CVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGFK 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE2 FGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 FGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGT 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE2 GFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 GFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLFS 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KE2 SQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 SQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQRV 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KE2 KLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 KLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSG 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KE2 SDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 SDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDT 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KE2 GRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 GRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTGP 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KE2 TLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 TLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSKS 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KE2 PAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 PAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKLY 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KE2 RYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 RYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTER 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KE2 VWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 VWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPR 2410 2420 2430 2440 2450 2460 2470 2480 2490 2500 2510 2520 pF1KE2 ESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 ESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSES 2470 2480 2490 2500 2510 2520 2530 2540 2550 2560 2570 2580 pF1KE2 VKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 VKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCELS 2530 2540 2550 2560 2570 2580 2590 2600 2610 2620 2630 2640 pF1KE2 KNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 KNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELTP 2590 2600 2610 2620 2630 2640 2650 2660 2670 2680 2690 2700 pF1KE2 TAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 TAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPLE 2650 2660 2670 2680 2690 2700 2710 2720 2730 2740 2750 2760 pF1KE2 ENTADNEKECIIVWEKKPTVEEKAKADTLKLPPTFFCGVCSDTDEDNGNGEDFQSELQKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 ENTADNEKECIIVWEKKPTVEEKAKADTLKLPPTFFCGVCSDTDEDNGNGEDFQSELQKV 2710 2720 2730 2740 2750 2760 2770 2780 2790 2800 2810 2820 pF1KE2 QEAQKSQTEEITSTTDSVYTGGTEVMVPSFCKSEEPDSITKSISSPSVSSETMDKPVDLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 QEAQKSQTEEITSTTDSVYTGGTEVMVPSFCKSEEPDSITKSISSPSVSSETMDKPVDLS 2770 2780 2790 2800 2810 2820 2830 2840 2850 2860 2870 2880 pF1KE2 TRKEIDTDSTSQGESKIVSFGFGSSTGLSFADLASSNSGDFAFGSKDKNFQWANTGAAVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 TRKEIDTDSTSQGESKIVSFGFGSSTGLSFADLASSNSGDFAFGSKDKNFQWANTGAAVF 2830 2840 2850 2860 2870 2880 2890 2900 2910 2920 2930 2940 pF1KE2 GTQSVGTQSAGKVGEDEDGSDEEVVHNEDIHFEPIVSLPEVEVKSGEEDEEILFKERAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 GTQSVGTQSAGKVGEDEDGSDEEVVHNEDIHFEPIVSLPEVEVKSGEEDEEILFKERAKL 2890 2900 2910 2920 2930 2940 2950 2960 2970 2980 2990 3000 pF1KE2 YRWDRDVSQWKERGVGDIKILWHTMKNYYRILMRRDQVFKVCANHVITKTMELKPLNVSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 YRWDRDVSQWKERGVGDIKILWHTMKNYYRILMRRDQVFKVCANHVITKTMELKPLNVSN 2950 2960 2970 2980 2990 3000 3010 3020 3030 3040 3050 3060 pF1KE2 NALVWTASDYADGEAKVEQLAVRFKTKEVADCFKKTFEECQQNLMKLQKGHVSLAAELSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 NALVWTASDYADGEAKVEQLAVRFKTKEVADCFKKTFEECQQNLMKLQKGHVSLAAELSK 3010 3020 3030 3040 3050 3060 3070 3080 3090 3100 3110 3120 pF1KE2 ETNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFGFKNSIFHRVIPDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 ETNPVVFFDVCADGEPLGRITMELFSNIVPRTAENFRALCTGEKGFGFKNSIFHRVIPDF 3070 3080 3090 3100 3110 3120 3130 3140 3150 3160 3170 3180 pF1KE2 VCQGGDITKHDGTGGQSIYGDKFEDENFDVKHTGPGLLSMANQGQNTNNSQFVITLKKAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 VCQGGDITKHDGTGGQSIYGDKFEDENFDVKHTGPGLLSMANQGQNTNNSQFVITLKKAE 3130 3140 3150 3160 3170 3180 3190 3200 3210 3220 pF1KE2 HLDFKHVVFGFVKDGMDTVKKIESFGSPKGSVCRRITITECGQI :::::::::::::::::::::::::::::::::::::::::::: CCDS20 HLDFKHVVFGFVKDGMDTVKKIESFGSPKGSVCRRITITECGQI 3190 3200 3210 3220 >>CCDS42729.1 RGPD6 gene_id:729540|Hs108|chr2 (904 aa) initn: 5170 init1: 2949 opt: 5506 Z-score: 4301.2 bits: 808.9 E(32554): 0 Smith-Waterman score: 5506; 94.9% identity (98.6% similar) in 870 aa overlap (1-869:1-869) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP :::::::::::.::: : :::::::::::::::::::::::::::::::::::::::::: CCDS42 MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:: CCDS42 KAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS42 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS42 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWQATNTDLLLAYA 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK ::::::::::::::.::::.::::::::.:: ::::::::::::::::::::.::::::: CCDS42 NLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMYAGSLLLK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..:::::::::::::::::::::::::::: .:.:::::::::::::::::::::: CCDS42 MGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLREGKAGQNLLEMMACDRLSQSGHMLL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL .:::::::::::.::::::: :::::::::::::::::::::::::::.:::.::::::: CCDS42 SLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPKDTSFLGSDDIGKIDVQEPELEDL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS42 ARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS42 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPFPVCKQLCTERQKSWWDAVCTLI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI ::::::::.:::::::::::::::::::::::::::::::. :::::::::::: : ::: CCDS42 HRKAVPGNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYI 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::.::: CCDS42 GRSVHYWKKVLPLLKIIKK-NSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAMLDA 610 620 630 640 650 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI ::::::::::::::::::::::::::::::::::::::::::::::::.::: ::::::: CCDS42 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST :::::.::::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS42 KIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::.:::::.::.::::.:::::::::::::::::::::.::: : CCDS42 PSPTKYSLSPSKSYKYSPETPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRH 780 790 800 810 820 830 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::: : CCDS42 RWPTENYGPDSVPDGYQGSQTFHGAPLTEAAHRHFTIEKHGDSKWIIYRFTKQLCGTERA 840 850 860 870 880 890 >>CCDS2083.1 RGPD5 gene_id:84220|Hs108|chr2 (904 aa) initn: 5170 init1: 2949 opt: 5506 Z-score: 4301.2 bits: 808.9 E(32554): 0 Smith-Waterman score: 5506; 94.9% identity (98.6% similar) in 870 aa overlap (1-869:1-869) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP :::::::::::.::: : :::::::::::::::::::::::::::::::::::::::::: CCDS20 MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:: CCDS20 KAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS20 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS20 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWQATNTDLLLAYA 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK ::::::::::::::.::::.::::::::.:: ::::::::::::::::::::.::::::: CCDS20 NLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMYAGSLLLK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..:::::::::::::::::::::::::::: .:.:::::::::::::::::::::: CCDS20 MGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLREGKAGQNLLEMMACDRLSQSGHMLL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL .:::::::::::.::::::: :::::::::::::::::::::::::::.:::.::::::: CCDS20 SLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPKDTSFLGSDDIGKIDVQEPELEDL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS20 ARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS20 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPFPVCKQLCTERQKSWWDAVCTLI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI ::::::::.:::::::::::::::::::::::::::::::. :::::::::::: : ::: CCDS20 HRKAVPGNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYI 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::.::: CCDS20 GRSVHYWKKVLPLLKIIKK-NSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAMLDA 610 620 630 640 650 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI ::::::::::::::::::::::::::::::::::::::::::::::::.::: ::::::: CCDS20 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST :::::.::::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS20 KIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::.:::::.::.::::.:::::::::::::::::::::.::: : CCDS20 PSPTKYSLSPSKSYKYSPETPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRH 780 790 800 810 820 830 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::: : CCDS20 RWPTENYGPDSVPDGYQGSQTFHGAPLTEAAHRHFTIEKHGDSKWIIYRFTKQLCGTERA 840 850 860 870 880 890 >>CCDS46358.2 RGPD1 gene_id:400966|Hs108|chr2 (1748 aa) initn: 7096 init1: 4648 opt: 4656 Z-score: 3634.0 bits: 686.4 E(32554): 4.3e-196 Smith-Waterman score: 8134; 59.0% identity (61.1% similar) in 2594 aa overlap (24-2616:15-1625) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP .....::::::::::::::::::::.:::..:::::: CCDS46 MNVMGFNTDRLAWTRNKLRGFYFAKLYYEAKEYDLAKKYVCTYLSVQERDP 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER .:::::::::::::::.:::::::::.:::: :::::::::::::::::::::::::.:: CCDS46 RAHRFLGLLYELEENTEKAVECYRRSLELNPPQKDLVLKIAELLCKNDVTDGRAKYWVER 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR ::::::::::::::::.::::::::::::::: :::::::::::::.::::::.:::.:: CCDS46 AAKLFPGSPAIYKLKEHLLDCEGEDGWNKLFDWIQSELYVRPDDVHMNIRLVELYRSNKR 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA 180 190 200 210 220 230 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK :::::::::::::::::::.::::::::.:: :::::::::::::::::::::::::::: CCDS46 NLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMHAGSLLLK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..::::.::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS46 MGQHGNNVQWQALSELAALCYVIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL ::::::::::::.:::::::::::.::.::::::: ::::::::::::::::.::::::: CCDS46 NLSRGKQDFLKEVVETFANKSGQSVLYNALFSSQSSKDTSFLGSDDIGNIDVQEPELEDL 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .:::::::.:::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS46 ARYDVGAIQAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: CCDS46 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKRLCTERQKSWWDAVCTLI 480 490 500 510 520 530 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI :::::::: :.:::.:::::::::::::::::::::::::.:::: : :::: :::.::: CCDS46 HRKAVPGNSAELRLVVQHEINTLRAQEKHGLQPALLVHWAKCLQKMGRGLNSSYDQQEYI 540 550 560 570 580 590 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: CCDS46 GRSVHYWKKVLPLLKIIKK-NSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA 600 610 620 630 640 650 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI :.:::::::::::::::::::::::::::::::::::::. ::::::::::::::::::: CCDS46 VHGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDAVFPEEQEECKNYLRKTRDYLI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: CCDS46 KIIDDSDSNLSVVKKLPVPLESVKEMLKSVMQELEDYSEGGPLYKNGSLRNADSEIKHST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::::::::::::::: :::::.:.:: : ::::.::: : CCDS46 PSPTKYSLSPSKSYKYSPKTPPRWAEDQNSLRKMICQEVKAITK------LNSSKSASRH 780 790 800 810 820 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK 830 840 850 860 870 880 900 910 920 930 940 950 pF1KE2 GPVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGD : CCDS46 G----------------------------------------------------------- 960 970 980 990 1000 1010 pF1KE2 DYFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSL CCDS46 ------------------------------------------------------------ 1020 1030 1040 1050 1060 1070 pF1KE2 PTQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGD CCDS46 ------------------------------------------------------------ 1080 1090 1100 1110 1120 1130 pF1KE2 GYSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGK CCDS46 ------------------------------------------------------------ 1140 1150 1160 1170 1180 1190 pF1KE2 SVFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRA CCDS46 ------------------------------------------------------------ 1200 1210 1220 1230 1240 1250 pF1KE2 KLFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAG CCDS46 ------------------------------------------------------------ 1260 1270 1280 1290 1300 1310 pF1KE2 SDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQA CCDS46 ------------------------------------------------------------ 1320 1330 1340 1350 1360 1370 pF1KE2 VRIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLN CCDS46 ------------------------------------------------------------ 1380 1390 1400 1410 1420 1430 pF1KE2 PSNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQ CCDS46 ------------------------------------------------------------ 1440 1450 1460 1470 1480 1490 pF1KE2 NTKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKC CCDS46 ------------------------------------------------------------ 1500 1510 1520 1530 1540 1550 pF1KE2 AACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEAN CCDS46 ------------------------------------------------------------ 1560 1570 1580 1590 1600 1610 pF1KE2 ATRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRN CCDS46 ------------------------------------------------------------ 1620 1630 1640 1650 1660 1670 pF1KE2 EASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE CCDS46 ------------------------------------------------------------ 1680 1690 1700 1710 1720 1730 pF1KE2 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA CCDS46 ------------------------------------------------------------ 1740 1750 1760 1770 1780 1790 pF1KE2 SATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSL CCDS46 ------------------------------------------------------------ 1800 1810 1820 1830 1840 1850 pF1KE2 KCVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGF CCDS46 ------------------------------------------------------------ 1860 1870 1880 1890 1900 1910 pF1KE2 KFGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG ::::::::::::::: :::::::::::::::::::::::::: CCDS46 -----------------SSNTEFKSTKEGFSIAVSADGFKFGISEPGNQEKKSEKPLEND 890 900 910 920 1920 1930 1940 1950 1960 1970 pF1KE2 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLF ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: CCDS46 TGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDPNFKGFSGAGEKLF 930 940 950 960 970 980 1980 1990 2000 2010 2020 2030 pF1KE2 SSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQR ::: ::::::::::::::::::: ::::::::::::::::::::::::::: ::::::: CCDS46 SSQCGKMANKANTSGDFEKDDDACKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQG 990 1000 1010 1020 1030 1040 2040 2050 2060 2070 2080 2090 pF1KE2 VKLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS :::::::::.::::::::::::::::::::: ::::::.::::::::::::::::::::: CCDS46 VKLFRFDAEISQWKERGLGNLKILKNEVNGKPRMLMRRDQVLKVCANHWITTTMNLKPLS 1050 1060 1070 1080 1090 1100 2100 2110 2120 2130 2140 2150 pF1KE2 GSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD :::::::::::::::::::::.:::.:::::::::::::::::::::::::::::::::: CCDS46 GSDRAWMWLASDFSDGDAKLERLAAQFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD 1110 1120 1130 1140 1150 1160 2160 2170 2180 2190 2200 2210 pF1KE2 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG 1170 1180 1190 1200 1210 1220 2220 2230 2240 2250 2260 2270 pF1KE2 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSK :::::::::::::::::.::::::: :::::::::::.::: ::::::::::::::: :: CCDS46 PTLEWDNYDLREDALDDNVSSSSVHDSPLASSPVRKNIFRFDESTTGFNFSFKSALSLSK 1230 1240 1250 1260 1270 1280 2280 2290 2300 2310 2320 2330 pF1KE2 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: CCDS46 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEL 1290 1300 1310 1320 1330 1340 2340 2350 2360 2370 2380 2390 pF1KE2 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTE :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS46 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTE 1350 1360 1370 1380 1390 1400 2400 2410 2420 2430 2440 2450 pF1KE2 RVWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP 1410 1420 1430 1440 1450 1460 2460 2470 2480 2490 2500 2510 pF1KE2 RESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSE ::::::::::::::::::::::::::::::::.:::::::::::: :::::::::::::: CCDS46 RESPCGKIAVAVLEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFGSE 1470 1480 1490 1500 1510 1520 2520 2530 2540 2550 2560 2570 pF1KE2 SVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL ::: :::::::.:::::::::::::::::::::::::.:::::::::::::::::::::: CCDS46 SVKRIFSSEKSNPFAFGNSSATGSLFGFSFNAPLKSNDSETSSVAQSGSESKVEPKKCEL 1530 1540 1550 1560 1570 1580 2580 2590 2600 2610 2620 2630 pF1KE2 SKNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELT ::::::::::::::::: :::: :::::::::::::: CCDS46 SKNSDIEQSSDSKVKNLSASFPMEESSINYTFKTPEKEPPLWHAEFTKEELVQKLSSTTK 1590 1600 1610 1620 1630 1640 2640 2650 2660 2670 2680 2690 pF1KE2 PTAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPL CCDS46 SADQLNGLLRETEATSAVLMEQIKLLKSEIRRLERNQEESAANVEHLKNVLLQFIFLKPG 1650 1660 1670 1680 1690 1700 >>CCDS42710.2 RGPD2 gene_id:729857|Hs108|chr2 (1756 aa) initn: 7092 init1: 4639 opt: 4647 Z-score: 3626.9 bits: 685.1 E(32554): 1.1e-195 Smith-Waterman score: 8230; 59.2% identity (61.3% similar) in 2617 aa overlap (1-2616:1-1633) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP :::::: :::.::::::.::: .: ..::::::::::::::::::::.:::..:::::: CCDS42 MRRSKAYGERYLASVQGSAPSPGKK-LRGFYFAKLYYEAKEYDLAKKYVCTYLSVQERDP 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER .:::::::::::::::.:::::::::.:::: :::::::::::::::::::::::::.:: CCDS42 RAHRFLGLLYELEENTEKAVECYRRSLELNPPQKDLVLKIAELLCKNDVTDGRAKYWVER 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR ::::::::::::::::.::::::::::::::: :::::::::::::.::::::.:::.:: CCDS42 AAKLFPGSPAIYKLKEHLLDCEGEDGWNKLFDWIQSELYVRPDDVHMNIRLVELYRSNKR 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA 180 190 200 210 220 230 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK :::::::::::::::::::.::::::::.:: :::::::::::::::::::::::::::: CCDS42 NLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMHAGSLLLK 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..::::.::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS42 MGQHGNNVQWQALSELAALCYVIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL 300 310 320 330 340 350 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL ::::::::::::.:::::::::::.::.::::::: ::::::::::::::::.::::::: CCDS42 NLSRGKQDFLKEVVETFANKSGQSVLYNALFSSQSSKDTSFLGSDDIGNIDVQEPELEDL 360 370 380 390 400 410 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .:::::::.:::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS42 ARYDVGAIQAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESI 420 430 440 450 460 470 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: CCDS42 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKRLCTERQKSWWDAVCTLI 480 490 500 510 520 530 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI :::::::: :.:::.:::::::::::::::::::::::::.:::: : :::: :::.::: CCDS42 HRKAVPGNSAELRLVVQHEINTLRAQEKHGLQPALLVHWAKCLQKMGRGLNSSYDQQEYI 540 550 560 570 580 590 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: CCDS42 GRSVHYWKKVLPLLKIIKK-NSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA 600 610 620 630 640 650 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI :.:::::::::::::::::::::::::::::::::::::. ::::::::::::::::::: CCDS42 VHGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDAVFPEEQEECKNYLRKTRDYLI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST :::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::: CCDS42 KIIDDSDSNLSVVKKLPVPLESVKEMLKSVMQELEDYSEGGPLYKNGSLRNADSEIKHST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::::::::::::::: :::::.:.:: : ::::.::: : CCDS42 PSPTKYSLSPSKSYKYSPKTPPRWAEDQNSLRKMICQEVKAITK------LNSSKSASRH 780 790 800 810 820 830 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK 840 850 860 870 880 890 900 910 920 930 940 950 pF1KE2 GPVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGD : CCDS42 G----------------------------------------------------------- 960 970 980 990 1000 1010 pF1KE2 DYFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSL CCDS42 ------------------------------------------------------------ 1020 1030 1040 1050 1060 1070 pF1KE2 PTQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGD CCDS42 ------------------------------------------------------------ 1080 1090 1100 1110 1120 1130 pF1KE2 GYSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGK CCDS42 ------------------------------------------------------------ 1140 1150 1160 1170 1180 1190 pF1KE2 SVFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRA CCDS42 ------------------------------------------------------------ 1200 1210 1220 1230 1240 1250 pF1KE2 KLFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAG CCDS42 ------------------------------------------------------------ 1260 1270 1280 1290 1300 1310 pF1KE2 SDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQA CCDS42 ------------------------------------------------------------ 1320 1330 1340 1350 1360 1370 pF1KE2 VRIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLN CCDS42 ------------------------------------------------------------ 1380 1390 1400 1410 1420 1430 pF1KE2 PSNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQ CCDS42 ------------------------------------------------------------ 1440 1450 1460 1470 1480 1490 pF1KE2 NTKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKC CCDS42 ------------------------------------------------------------ 1500 1510 1520 1530 1540 1550 pF1KE2 AACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEAN CCDS42 ------------------------------------------------------------ 1560 1570 1580 1590 1600 1610 pF1KE2 ATRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRN CCDS42 ------------------------------------------------------------ 1620 1630 1640 1650 1660 1670 pF1KE2 EASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE CCDS42 ------------------------------------------------------------ 1680 1690 1700 1710 1720 1730 pF1KE2 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA CCDS42 ------------------------------------------------------------ 1740 1750 1760 1770 1780 1790 pF1KE2 SATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSL CCDS42 ------------------------------------------------------------ 1800 1810 1820 1830 1840 1850 pF1KE2 KCVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGF CCDS42 ------------------------------------------------------------ 1860 1870 1880 1890 1900 1910 pF1KE2 KFGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG ::::::::::::::: :::::::::::::::::::::::::: CCDS42 -----------------SSNTEFKSTKEGFSIAVSADGFKFGISEPGNQEKKSEKPLEND 900 910 920 930 1920 1930 1940 1950 1960 1970 pF1KE2 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLF ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: CCDS42 TGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDPNFKGFSGAGEKLF 940 950 960 970 980 990 1980 1990 2000 2010 2020 2030 pF1KE2 SSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQR ::: ::::::::::::::::::: ::::::::::::::::::::::::::: ::::::: CCDS42 SSQCGKMANKANTSGDFEKDDDACKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQG 1000 1010 1020 1030 1040 1050 2040 2050 2060 2070 2080 2090 pF1KE2 VKLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS :::::::::.::::::::::::::::::::: ::::::.::::::::::::::::::::: CCDS42 VKLFRFDAEISQWKERGLGNLKILKNEVNGKPRMLMRRDQVLKVCANHWITTTMNLKPLS 1060 1070 1080 1090 1100 1110 2100 2110 2120 2130 2140 2150 pF1KE2 GSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD :::::::::::::::::::::.:::.:::::::::::::::::::::::::::::::::: CCDS42 GSDRAWMWLASDFSDGDAKLERLAAQFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD 1120 1130 1140 1150 1160 1170 2160 2170 2180 2190 2200 2210 pF1KE2 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG 1180 1190 1200 1210 1220 1230 2220 2230 2240 2250 2260 2270 pF1KE2 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSK :::::::::::::::::.::::::: :::::::::::.::: ::::::::::::::: :: CCDS42 PTLEWDNYDLREDALDDNVSSSSVHDSPLASSPVRKNIFRFDESTTGFNFSFKSALSLSK 1240 1250 1260 1270 1280 1290 2280 2290 2300 2310 2320 2330 pF1KE2 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: :.: CCDS42 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHMAEL 1300 1310 1320 1330 1340 1350 2340 2350 2360 2370 2380 2390 pF1KE2 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTE :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS42 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTE 1360 1370 1380 1390 1400 1410 2400 2410 2420 2430 2440 2450 pF1KE2 RVWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP 1420 1430 1440 1450 1460 1470 2460 2470 2480 2490 2500 2510 pF1KE2 RESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSE ::::::::::::::::::::::::::::::::.:::::::::::: :::::::::::::: CCDS42 RESPCGKIAVAVLEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFGSE 1480 1490 1500 1510 1520 1530 2520 2530 2540 2550 2560 2570 pF1KE2 SVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL ::: :::::::.:::::::::::::::::::::::::.:::::::::::::::::::::: CCDS42 SVKRIFSSEKSNPFAFGNSSATGSLFGFSFNAPLKSNDSETSSVAQSGSESKVEPKKCEL 1540 1550 1560 1570 1580 1590 2580 2590 2600 2610 2620 2630 pF1KE2 SKNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELT ::::::::::::::::: :::: :::::::::::::: CCDS42 SKNSDIEQSSDSKVKNLSASFPMEESSINYTFKTPEKEPPLWHAEFTKEELVQKLSSTTK 1600 1610 1620 1630 1640 1650 2640 2650 2660 2670 2680 2690 pF1KE2 PTAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPL CCDS42 SADQLNGLLRETEATSAVLMEQIKLLKSEIRRLERNQEESAANVEHLKNVLLQFIFLKPG 1660 1670 1680 1690 1700 1710 >>CCDS46381.1 RGPD4 gene_id:285190|Hs108|chr2 (1758 aa) initn: 6295 init1: 4643 opt: 4643 Z-score: 3623.8 bits: 684.5 E(32554): 1.6e-195 Smith-Waterman score: 8384; 60.0% identity (61.5% similar) in 2617 aa overlap (1-2616:1-1641) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP : ::: :::.::::::.::::.:: .:::::::::::::::::::::::::::.: :: CCDS46 MSCSKAYGERYVASVQGSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER .:::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:: CCDS46 RAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS46 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK :::::::::::::::::::.::::::::.:: :::::::::::::::::::::::::::: CCDS46 NLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMHAGSLLLK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..:::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL ::::::::::: .:::::::::::::::::::::::::::::::::::::::.::::::: CCDS46 NLSRGKQDFLKVVVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVQEPELEDL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS46 ARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI :::::::: :::::::::::::::::::::::::::::::.:::: :::::::::::::: CCDS46 HRKAVPGNSAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKCLQKMGSGLNSFYDQREYI 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: CCDS46 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHVTFAILDA 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI ::::::::.:::::::::::::::::::::::::: :::::::::::::::::::: ::: CCDS46 VNGNIEDAMTAFESIKSVVSYWNLALIFHRKAEDIANDALSPEEQEECKNYLRKTRGYLI 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST ::.::::::::::::::::::::::::.:::::::.:::: ::::::::::::::::::: CCDS46 KILDDSDSNLSVVKKLPVPLESVKEMLKSVMQELENYSEGDPLYKNGSLRNADSEIKHST 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::::::::::::::::::: :.:.:::.::::::::::.::: : CCDS46 PSPTKYSLSPSKSYKYSPKTPPRWAEDQNSLLKMIRQEVKAIKEEMQELKLNSSKSASHH 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE2 GPVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGD : CCDS46 G----------------------------------------------------------- 960 970 980 990 1000 1010 pF1KE2 DYFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSL CCDS46 ------------------------------------------------------------ 1020 1030 1040 1050 1060 1070 pF1KE2 PTQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGD CCDS46 ------------------------------------------------------------ 1080 1090 1100 1110 1120 1130 pF1KE2 GYSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGK CCDS46 ------------------------------------------------------------ 1140 1150 1160 1170 1180 1190 pF1KE2 SVFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRA CCDS46 ------------------------------------------------------------ 1200 1210 1220 1230 1240 1250 pF1KE2 KLFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAG CCDS46 ------------------------------------------------------------ 1260 1270 1280 1290 1300 1310 pF1KE2 SDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQA CCDS46 ------------------------------------------------------------ 1320 1330 1340 1350 1360 1370 pF1KE2 VRIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLN CCDS46 ------------------------------------------------------------ 1380 1390 1400 1410 1420 1430 pF1KE2 PSNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQ CCDS46 ------------------------------------------------------------ 1440 1450 1460 1470 1480 1490 pF1KE2 NTKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKC CCDS46 ------------------------------------------------------------ 1500 1510 1520 1530 1540 1550 pF1KE2 AACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEAN CCDS46 ------------------------------------------------------------ 1560 1570 1580 1590 1600 1610 pF1KE2 ATRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRN CCDS46 ------------------------------------------------------------ 1620 1630 1640 1650 1660 1670 pF1KE2 EASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE CCDS46 ------------------------------------------------------------ 1680 1690 1700 1710 1720 1730 pF1KE2 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA CCDS46 ------------------------------------------------------------ 1740 1750 1760 1770 1780 1790 pF1KE2 SATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSL CCDS46 ------------------------------------------------------------ 1800 1810 1820 1830 1840 1850 pF1KE2 KCVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGF CCDS46 ------------------------------------------------------------ 1860 1870 1880 1890 1900 1910 pF1KE2 KFGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG ::::::::::::::::::::::::::::::::::.::::::: CCDS46 -----------------SSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKESEKPLEND 910 920 930 940 1920 1930 1940 1950 1960 1970 pF1KE2 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLF ::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::: CCDS46 TGFQAQDISGQKNGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDPNFKGFSGAGEKLF 950 960 970 980 990 1000 1980 1990 2000 2010 2020 2030 pF1KE2 SSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQR ::: ::::::::::::::::::::::::::::::::::::::::::: ::: ::::::: CCDS46 SSQCGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVIGEEGEKVLYSQG 1010 1020 1030 1040 1050 1060 2040 2050 2060 2070 2080 2090 pF1KE2 VKLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS :::::::::: :::::::::::::::::::: :::::::::::::::::::::::::::: CCDS46 VKLFRFDAEVRQWKERGLGNLKILKNEVNGKPRMLMRREQVLKVCANHWITTTMNLKPLS 1070 1080 1090 1100 1110 1120 2100 2110 2120 2130 2140 2150 pF1KE2 GSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD :::::::: ::::::::::::.::::::::::::::::::::::.::::::::::::::: CCDS46 GSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQQLLLDIPLQTPHKLVD 1130 1140 1150 1160 1170 1180 2160 2170 2180 2190 2200 2210 pF1KE2 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG 1190 1200 1210 1220 1230 1240 2220 2230 2240 2250 2260 2270 pF1KE2 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSK ::::::: :::::::::::::::::::::::::::::::.::::::: :::::::::::: CCDS46 PTLEWDNCDLREDALDDSVSSSSVHASPLASSPVRKNLFHFGESTTGSNFSFKSALSPSK 1250 1260 1270 1280 1290 1300 2280 2290 2300 2310 2320 2330 pF1KE2 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKL ::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::.: CCDS46 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEKVVFSHRAEL 1310 1320 1330 1340 1350 1360 2340 2350 2360 2370 2380 2390 pF1KE2 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTE ::::::::::::::::::::::::::::::::::::::::::::: :::::.:::::::: CCDS46 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHTITPDMSLQNMKGTE 1370 1380 1390 1400 1410 1420 2400 2410 2420 2430 2440 2450 pF1KE2 RVWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP 1430 1440 1450 1460 1470 1480 2460 2470 2480 2490 2500 2510 pF1KE2 RESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSE ::::::::::::::::::::::::::::::::.:::::::::::: :::::::::::::: CCDS46 RESPCGKIAVAVLEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFGSE 1490 1500 1510 1520 1530 1540 2520 2530 2540 2550 2560 2570 pF1KE2 SVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL ::: :::::::::::::::::::::::::::: ::::::::::::::::::::::::::: CCDS46 SVKRIFSSEKSKPFAFGNSSATGSLFGFSFNASLKSNNSETSSVAQSGSESKVEPKKCEL 1550 1560 1570 1580 1590 1600 2580 2590 2600 2610 2620 2630 pF1KE2 SKNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELT ::::::::::::::::: :::: :::::::::::::: CCDS46 SKNSDIEQSSDSKVKNLSASFPMEESSINYTFKTPEKEPPLWHAEFTKEELVQKLSSTTK 1610 1620 1630 1640 1650 1660 2640 2650 2660 2670 2680 2690 pF1KE2 PTAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPL CCDS46 SADHLNGLLREAEATSAVLMEQIKLLKSEIRRLERNQEQEESAANVEHLKNVLLQFIFLK 1670 1680 1690 1700 1710 1720 >>CCDS46379.1 RGPD3 gene_id:653489|Hs108|chr2 (1758 aa) initn: 6277 init1: 4630 opt: 4630 Z-score: 3613.7 bits: 682.7 E(32554): 5.8e-195 Smith-Waterman score: 8375; 60.0% identity (61.7% similar) in 2617 aa overlap (1-2616:1-1641) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP : ::: :::.::::::.::::.:: .:::::::::::::::::::::::::::.: :: CCDS46 MSCSKAYGERYVASVQGSAPSPRKKSTRGFYFAKLYYEAKEYDLAKKYICTYINVREMDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER .:::::::::::::::.:::::::::::::::::::::::::::::::::::::.::.:: CCDS46 RAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAEYWVER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS46 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA ::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LKDAVARCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK :::::::::::::::::::.::::::::.:: :::::::::::::::::::::::::::: CCDS46 NLMLLTLSTRDVQESRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMHAGSLLLK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..:::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL ::::::::::: .:::::::::::::::::::::::::::::::::::::::.::::::: CCDS46 NLSRGKQDFLKVVVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVQEPELEDL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: CCDS46 ARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPQETSRLETNAPESI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI :::::::: :::::::::::::::::::::::::::::::.:::: :::::::::::::: CCDS46 HRKAVPGNSAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKCLQKMGSGLNSFYDQREYI 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: CCDS46 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHVTFAILDA 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI ::::::::.:::::::::::::::::::::::::: :::::::::::::::::::: ::: CCDS46 VNGNIEDAMTAFESIKSVVSYWNLALIFHRKAEDIANDALSPEEQEECKNYLRKTRGYLI 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST ::.::::::::::::::::::::::::.:::::::.:::::::::::::::::::::::: CCDS46 KILDDSDSNLSVVKKLPVPLESVKEMLKSVMQELENYSEGGPLYKNGSLRNADSEIKHST 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::::::::::::::::::: :.:.:::.::::::::::.::: : CCDS46 PSPTKYSLSPSKSYKYSPKTPPRWAEDQNSLLKMIRQEVKAIKEEMQELKLNSSKSASHH 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE2 GPVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGD : CCDS46 G----------------------------------------------------------- 960 970 980 990 1000 1010 pF1KE2 DYFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSL CCDS46 ------------------------------------------------------------ 1020 1030 1040 1050 1060 1070 pF1KE2 PTQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGD CCDS46 ------------------------------------------------------------ 1080 1090 1100 1110 1120 1130 pF1KE2 GYSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGK CCDS46 ------------------------------------------------------------ 1140 1150 1160 1170 1180 1190 pF1KE2 SVFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRA CCDS46 ------------------------------------------------------------ 1200 1210 1220 1230 1240 1250 pF1KE2 KLFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAG CCDS46 ------------------------------------------------------------ 1260 1270 1280 1290 1300 1310 pF1KE2 SDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQA CCDS46 ------------------------------------------------------------ 1320 1330 1340 1350 1360 1370 pF1KE2 VRIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLN CCDS46 ------------------------------------------------------------ 1380 1390 1400 1410 1420 1430 pF1KE2 PSNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQ CCDS46 ------------------------------------------------------------ 1440 1450 1460 1470 1480 1490 pF1KE2 NTKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKC CCDS46 ------------------------------------------------------------ 1500 1510 1520 1530 1540 1550 pF1KE2 AACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEAN CCDS46 ------------------------------------------------------------ 1560 1570 1580 1590 1600 1610 pF1KE2 ATRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRN CCDS46 ------------------------------------------------------------ 1620 1630 1640 1650 1660 1670 pF1KE2 EASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE CCDS46 ------------------------------------------------------------ 1680 1690 1700 1710 1720 1730 pF1KE2 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA CCDS46 ------------------------------------------------------------ 1740 1750 1760 1770 1780 1790 pF1KE2 SATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSL CCDS46 ------------------------------------------------------------ 1800 1810 1820 1830 1840 1850 pF1KE2 KCVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGF CCDS46 ------------------------------------------------------------ 1860 1870 1880 1890 1900 1910 pF1KE2 KFGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG :::::::::::::::::::::::::::::::::::::::::: CCDS46 -----------------SSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLEND 910 920 930 940 1920 1930 1940 1950 1960 1970 pF1KE2 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLF ::.:::::::.:.:::::::::::::::::.::::::::::::::: ::::::::::::: CCDS46 TGLQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLF 950 960 970 980 990 1000 1980 1990 2000 2010 2020 2030 pF1KE2 SSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQR ::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS46 SSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQG 1010 1020 1030 1040 1050 1060 2040 2050 2060 2070 2080 2090 pF1KE2 VKLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS :::::::::::::::::::::::::::::::.::::.::::::::::::::::::::::: CCDS46 VKLFRFDAEVSQWKERGLGNLKILKNEVNGKVRMLMQREQVLKVCANHWITTTMNLKPLS 1070 1080 1090 1100 1110 1120 2100 2110 2120 2130 2140 2150 pF1KE2 GSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS46 GSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD 1130 1140 1150 1160 1170 1180 2160 2170 2180 2190 2200 2210 pF1KE2 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG ::::::::::::::::::::::::::::::::.:::::::::::::::::::::: :::: CCDS46 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVAEEENKGSGTGAAGASDTTIKPNAENTG 1190 1200 1210 1220 1230 1240 2220 2230 2240 2250 2260 2270 pF1KE2 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSK :::::::::::::::::::::::::::::::::::::::.: ::::: ::::::::: :: CCDS46 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFHFDESTTGSNFSFKSALSLSK 1250 1260 1270 1280 1290 1300 2280 2290 2300 2310 2320 2330 pF1KE2 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.. CCDS46 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEF 1310 1320 1330 1340 1350 1360 2340 2350 2360 2370 2380 2390 pF1KE2 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTE :::::::::::::::::::::::::::.:::.:::::::::::::::::::.:::::::: CCDS46 YRYDKDVGQWKERGIGDIKILQNYDNKHVRILMRRDQVLKLCANHRITPDMSLQNMKGTE 1370 1380 1390 1400 1410 1420 2400 2410 2420 2430 2440 2450 pF1KE2 RVWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP 1430 1440 1450 1460 1470 1480 2460 2470 2480 2490 2500 2510 pF1KE2 RESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSE ::::::::::::::::::::::::::::::::.:::::::::::: :::::::::::::: CCDS46 RESPCGKIAVAVLEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFGSE 1490 1500 1510 1520 1530 1540 2520 2530 2540 2550 2560 2570 pF1KE2 SVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SVKRIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL 1550 1560 1570 1580 1590 1600 2580 2590 2600 2610 2620 2630 pF1KE2 SKNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELT ::::::::::::::::: ::::::::::::::::::: CCDS46 SKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEKEPPLWYAEFTKEELVQKLSSTTK 1610 1620 1630 1640 1650 1660 2640 2650 2660 2670 2680 2690 pF1KE2 PTAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPL CCDS46 SADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEQEVSAANVEHLKNVLLQFIFLK 1670 1680 1690 1700 1710 1720 >>CCDS46388.1 RGPD6 gene_id:729540|Hs108|chr2 (1765 aa) initn: 4622 init1: 4622 opt: 4624 Z-score: 3609.0 bits: 681.8 E(32554): 1.1e-194 Smith-Waterman score: 8368; 60.0% identity (61.7% similar) in 2617 aa overlap (1-2616:1-1640) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP :::::::::::.::: : :::::::::::::::::::::::::::::::::::::::::: CCDS46 MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:: CCDS46 KAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS46 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS46 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWQATNTDLLLAYA 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK ::::::::::::::.::::.::::::::.:: ::::::::::::::::::::.::::::: CCDS46 NLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMYAGSLLLK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..:::::::::::::::::::::::::::: .:.:::::::::::::::::::::: CCDS46 MGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLREGKAGQNLLEMMACDRLSQSGHMLL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL .:::::::::::.::::::: :::::::::::::::::::::::::::.:::.::::::: CCDS46 SLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPKDTSFLGSDDIGKIDVQEPELEDL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS46 ARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS46 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPFPVCKQLCTERQKSWWDAVCTLI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI ::::::::.:::::::::::::::::::::::::::::::. :::::::::::: : ::: CCDS46 HRKAVPGNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYI 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::.::: CCDS46 GRSVHYWKKVLPLLKIIKK-NSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAMLDA 610 620 630 640 650 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI ::::::::::::::::::::::::::::::::::::::::::::::::.::: ::::::: CCDS46 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST :::::.::::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS46 KIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::.:::::.::.::::.:::::::::::::::::::::.::: : CCDS46 PSPTKYSLSPSKSYKYSPETPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRH 780 790 800 810 820 830 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK 840 850 860 870 880 890 900 910 920 930 940 950 pF1KE2 GPVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGD : CCDS46 G----------------------------------------------------------- 900 960 970 980 990 1000 1010 pF1KE2 DYFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSL CCDS46 ------------------------------------------------------------ 1020 1030 1040 1050 1060 1070 pF1KE2 PTQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGD CCDS46 ------------------------------------------------------------ 1080 1090 1100 1110 1120 1130 pF1KE2 GYSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGK CCDS46 ------------------------------------------------------------ 1140 1150 1160 1170 1180 1190 pF1KE2 SVFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRA CCDS46 ------------------------------------------------------------ 1200 1210 1220 1230 1240 1250 pF1KE2 KLFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAG CCDS46 ------------------------------------------------------------ 1260 1270 1280 1290 1300 1310 pF1KE2 SDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQA CCDS46 ------------------------------------------------------------ 1320 1330 1340 1350 1360 1370 pF1KE2 VRIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLN CCDS46 ------------------------------------------------------------ 1380 1390 1400 1410 1420 1430 pF1KE2 PSNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQ CCDS46 ------------------------------------------------------------ 1440 1450 1460 1470 1480 1490 pF1KE2 NTKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKC CCDS46 ------------------------------------------------------------ 1500 1510 1520 1530 1540 1550 pF1KE2 AACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEAN CCDS46 ------------------------------------------------------------ 1560 1570 1580 1590 1600 1610 pF1KE2 ATRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRN CCDS46 ------------------------------------------------------------ 1620 1630 1640 1650 1660 1670 pF1KE2 EASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE CCDS46 ------------------------------------------------------------ 1680 1690 1700 1710 1720 1730 pF1KE2 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA CCDS46 ------------------------------------------------------------ 1740 1750 1760 1770 1780 1790 pF1KE2 SATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSL CCDS46 ------------------------------------------------------------ 1800 1810 1820 1830 1840 1850 pF1KE2 KCVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGF CCDS46 ------------------------------------------------------------ 1860 1870 1880 1890 1900 1910 pF1KE2 KFGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG ::::::::::::::::::::::::::::::::::: :::::: CCDS46 -----------------SSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKREKPLEND 910 920 930 940 1920 1930 1940 1950 1960 1970 pF1KE2 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLF ::::::::::.:.:::::::::::::::::.::::::::::::::: ::::::::::::: CCDS46 TGFQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLF 950 960 970 980 990 1000 1980 1990 2000 2010 2020 2030 pF1KE2 SSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQR ::.:::::::::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS46 SSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQG 1010 1020 1030 1040 1050 1060 2040 2050 2060 2070 2080 2090 pF1KE2 VKLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VKLFRFDAEVRQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS 1070 1080 1090 1100 1110 1120 2100 2110 2120 2130 2140 2150 pF1KE2 GSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS46 GSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD 1130 1140 1150 1160 1170 1180 2160 2170 2180 2190 2200 2210 pF1KE2 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG ::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: CCDS46 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNAENTG 1190 1200 1210 1220 1230 1240 2220 2230 2240 2250 2260 2270 pF1KE2 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSK ::::::::::::::::::::::::::::::::::::::::: ::::: ::::::::: :: CCDS46 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFDESTTGSNFSFKSALSLSK 1250 1260 1270 1280 1290 1300 2280 2290 2300 2310 2320 2330 pF1KE2 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKL :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::.. CCDS46 SPAKLNQSGTSVGTDEESVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEI 1310 1320 1330 1340 1350 1360 2340 2350 2360 2370 2380 2390 pF1KE2 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTE :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS46 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTE 1370 1380 1390 1400 1410 1420 2400 2410 2420 2430 2440 2450 pF1KE2 RVWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP 1430 1440 1450 1460 1470 1480 2460 2470 2480 2490 2500 2510 pF1KE2 RESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSE :::::::::::.::::::::::::::::::::.:::::::::::: ::::::::::: :: CCDS46 RESPCGKIAVAILEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFVSE 1490 1500 1510 1520 1530 1540 2520 2530 2540 2550 2560 2570 pF1KE2 SVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL ::: ::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SVKRIFSSEKSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL 1550 1560 1570 1580 1590 1600 2580 2590 2600 2610 2620 2630 pF1KE2 SKNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELT ::::::::::::::::: ::::::::::::::::::: CCDS46 SKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTK 1610 1620 1630 1640 1650 1660 2640 2650 2660 2670 2680 2690 pF1KE2 PTAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPL CCDS46 SADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLK 1670 1680 1690 1700 1710 1720 >>CCDS2082.1 RGPD5 gene_id:84220|Hs108|chr2 (1765 aa) initn: 4622 init1: 4622 opt: 4624 Z-score: 3609.0 bits: 681.8 E(32554): 1.1e-194 Smith-Waterman score: 8368; 60.0% identity (61.7% similar) in 2617 aa overlap (1-2616:1-1640) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP :::::::::::.::: : :::::::::::::::::::::::::::::::::::::::::: CCDS20 MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:: CCDS20 KAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS20 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS20 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWQATNTDLLLAYA 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK ::::::::::::::.::::.::::::::.:: ::::::::::::::::::::.::::::: CCDS20 NLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMYAGSLLLK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..:::::::::::::::::::::::::::: .:.:::::::::::::::::::::: CCDS20 MGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLREGKAGQNLLEMMACDRLSQSGHMLL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL .:::::::::::.::::::: :::::::::::::::::::::::::::.:::.::::::: CCDS20 SLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPKDTSFLGSDDIGKIDVQEPELEDL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS20 ARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS20 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPFPVCKQLCTERQKSWWDAVCTLI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI ::::::::.:::::::::::::::::::::::::::::::. :::::::::::: : ::: CCDS20 HRKAVPGNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYI 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::: ::::::::::::::::::::::::::::::::::::.::: CCDS20 GRSVHYWKKVLPLLKIIKK-NSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAMLDA 610 620 630 640 650 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI ::::::::::::::::::::::::::::::::::::::::::::::::.::: ::::::: CCDS20 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST :::::.::::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS20 KIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::.:::::.::.::::.:::::::::::::::::::::.::: : CCDS20 PSPTKYSLSPSKSYKYSPETPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRH 780 790 800 810 820 830 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK 840 850 860 870 880 890 900 910 920 930 940 950 pF1KE2 GPVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGD : CCDS20 G----------------------------------------------------------- 900 960 970 980 990 1000 1010 pF1KE2 DYFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSL CCDS20 ------------------------------------------------------------ 1020 1030 1040 1050 1060 1070 pF1KE2 PTQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGD CCDS20 ------------------------------------------------------------ 1080 1090 1100 1110 1120 1130 pF1KE2 GYSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGK CCDS20 ------------------------------------------------------------ 1140 1150 1160 1170 1180 1190 pF1KE2 SVFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRA CCDS20 ------------------------------------------------------------ 1200 1210 1220 1230 1240 1250 pF1KE2 KLFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAG CCDS20 ------------------------------------------------------------ 1260 1270 1280 1290 1300 1310 pF1KE2 SDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQA CCDS20 ------------------------------------------------------------ 1320 1330 1340 1350 1360 1370 pF1KE2 VRIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLN CCDS20 ------------------------------------------------------------ 1380 1390 1400 1410 1420 1430 pF1KE2 PSNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQ CCDS20 ------------------------------------------------------------ 1440 1450 1460 1470 1480 1490 pF1KE2 NTKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKC CCDS20 ------------------------------------------------------------ 1500 1510 1520 1530 1540 1550 pF1KE2 AACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEAN CCDS20 ------------------------------------------------------------ 1560 1570 1580 1590 1600 1610 pF1KE2 ATRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRN CCDS20 ------------------------------------------------------------ 1620 1630 1640 1650 1660 1670 pF1KE2 EASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE CCDS20 ------------------------------------------------------------ 1680 1690 1700 1710 1720 1730 pF1KE2 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA CCDS20 ------------------------------------------------------------ 1740 1750 1760 1770 1780 1790 pF1KE2 SATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSL CCDS20 ------------------------------------------------------------ 1800 1810 1820 1830 1840 1850 pF1KE2 KCVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGF CCDS20 ------------------------------------------------------------ 1860 1870 1880 1890 1900 1910 pF1KE2 KFGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG ::::::::::::::::::::::::::::::::::: :::::: CCDS20 -----------------SSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKREKPLEND 910 920 930 940 1920 1930 1940 1950 1960 1970 pF1KE2 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLF ::::::::::.:.:::::::::::::::::.::::::::::::::: ::::::::::::: CCDS20 TGFQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLF 950 960 970 980 990 1000 1980 1990 2000 2010 2020 2030 pF1KE2 SSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQR ::.:::::::::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS20 SSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQG 1010 1020 1030 1040 1050 1060 2040 2050 2060 2070 2080 2090 pF1KE2 VKLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 VKLFRFDAEVRQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS 1070 1080 1090 1100 1110 1120 2100 2110 2120 2130 2140 2150 pF1KE2 GSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS20 GSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD 1130 1140 1150 1160 1170 1180 2160 2170 2180 2190 2200 2210 pF1KE2 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG ::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::: CCDS20 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNAENTG 1190 1200 1210 1220 1230 1240 2220 2230 2240 2250 2260 2270 pF1KE2 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSK ::::::::::::::::::::::::::::::::::::::::: ::::: ::::::::: :: CCDS20 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFDESTTGSNFSFKSALSLSK 1250 1260 1270 1280 1290 1300 2280 2290 2300 2310 2320 2330 pF1KE2 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKL :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::.. CCDS20 SPAKLNQSGTSVGTDEESVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEI 1310 1320 1330 1340 1350 1360 2340 2350 2360 2370 2380 2390 pF1KE2 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTE :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS20 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTE 1370 1380 1390 1400 1410 1420 2400 2410 2420 2430 2440 2450 pF1KE2 RVWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS20 RVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP 1430 1440 1450 1460 1470 1480 2460 2470 2480 2490 2500 2510 pF1KE2 RESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSE :::::::::::.::::::::::::::::::::.:::::::::::: ::::::::::: :: CCDS20 RESPCGKIAVAILEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFVSE 1490 1500 1510 1520 1530 1540 2520 2530 2540 2550 2560 2570 pF1KE2 SVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL ::: ::::::::::.::::::::::::::::::::::::::::::::::::::::::::: CCDS20 SVKRIFSSEKSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL 1550 1560 1570 1580 1590 1600 2580 2590 2600 2610 2620 2630 pF1KE2 SKNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELT ::::::::::::::::: ::::::::::::::::::: CCDS20 SKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTK 1610 1620 1630 1640 1650 1660 2640 2650 2660 2670 2680 2690 pF1KE2 PTAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPL CCDS20 SADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLK 1670 1680 1690 1700 1710 1720 >>CCDS46394.1 RGPD8 gene_id:727851|Hs108|chr2 (1765 aa) initn: 4604 init1: 4604 opt: 4606 Z-score: 3594.9 bits: 679.2 E(32554): 6.4e-194 Smith-Waterman score: 8359; 60.0% identity (61.6% similar) in 2617 aa overlap (1-2616:1-1640) 10 20 30 40 50 60 pF1KE2 MRRSKADVERYIASVQGSTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP :::::::::::.::: : :::::::::::::::::::::::::::::::::::::::::: CCDS46 MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDLAKKYICTYINVQERDP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KAHRFLGLLYELEENTDKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWLER ::::::::::::::::.::::::::::::::::::::::::::::::::::::::::.:: CCDS46 KAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAELLCKNDVTDGRAKYWVER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVEVYRSTKR :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::: CCDS46 AAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYVRPDDVHVNIRLVELYRSTKR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESLQCLESDKSDWRATNTDLLLAYA 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 NLMLLTLSTRDVQESRELLQSFDSALQSVKS-LGGNDELSATFLEMKGHFYMHAGSLLLK ::::::::::::::.::::.::::::::.:: ::::::::::::::::::::.::::::: CCDS46 NLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGNDELSATFLEMKGHFYMYAGSLLLK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE2 MGQHSSNVQWRALSELAALCYLIAFQVPRPKIKLIKGEAGQNLLEMMACDRLSQSGHMLL ::::..:::::::::::::::::::::::::::: .:.:::::::::::::::::::::: CCDS46 MGQHGNNVQWRALSELAALCYLIAFQVPRPKIKLREGKAGQNLLEMMACDRLSQSGHMLL 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE2 NLSRGKQDFLKEIVETFANKSGQSALYDALFSSQSPKDTSFLGSDDIGNIDVREPELEDL .:::::::::::.::::::: :::::::::::::::::::::::::::.:::.::::::: CCDS46 SLSRGKQDFLKEVVETFANKIGQSALYDALFSSQSPKDTSFLGSDDIGKIDVQEPELEDL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE2 TRYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHHLPHETSRLETNAPESI .::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: CCDS46 ARYDVGAIRAHNGSLQHLTWLGLQWNSLPALPGIRKWLKQLFHRLPHETSRLETNAPESI 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE2 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPLPVCKQLCTERQKSWWDAVCTLI :::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::: CCDS46 CILDLEVFLLGVVYTSHLQLKEKCNSHHSSYQPLCLPFPVCKQLCTERQKSWWDAVCTLI 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE2 HRKAVPGNVAKLRLLVQHEINTLRAQEKHGLQPALLVHWAECLQKTGSGLNSFYDQREYI ::::::::.:::::::::::::::::::::::::::::::. :::::::::::: : ::: CCDS46 HRKAVPGNLAKLRLLVQHEINTLRAQEKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYI 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE2 GRSVHYWKKVLPLLKIIKKKNSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA ::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::: CCDS46 GRSVHYWKKVLPLLKIIKK-NSIPEPIDPLFKHFHSVDIQASEIVEYEEDAHITFAILDA 610 620 630 640 650 660 670 680 690 700 710 pF1KE2 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECKNYLRKTRDYLI ::::::::::::::::::::::::::::::::::::::::::::::::.::: ::::::: CCDS46 VNGNIEDAVTAFESIKSVVSYWNLALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLI 660 670 680 690 700 710 720 730 740 750 760 770 pF1KE2 KIIDDSDSNLSVVKKLPVPLESVKEMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST :::::.::::::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS46 KIIDDGDSNLSVVKKLPVPLESVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHST 720 730 740 750 760 770 780 790 800 810 820 830 pF1KE2 PSPTRYSLSPSKSYKYSPKTPPRWAEDQNSLLKMICQQVEAIKKEMQELKLNSSNSASPH ::::.:::::::::::::.:::::.::.::::.:::::::::::::::::::::.::: : CCDS46 PSPTKYSLSPSKSYKYSPETPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRH 780 790 800 810 820 830 840 850 860 870 880 890 pF1KE2 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RWPTENYGPDSVPDGYQGSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTK 840 850 860 870 880 890 900 910 920 930 940 950 pF1KE2 GPVYGMNRLPPQQHIYAYPQQMHTPPVQSSSACMFSQEMYGPPALRFESPATGILSPRGD : CCDS46 G----------------------------------------------------------- 900 960 970 980 990 1000 1010 pF1KE2 DYFNYNVQQTSTNPPLPEPGYFTKPPIAAHASRSAESKTIEFGKTNFVQPMPGEGLRPSL CCDS46 ------------------------------------------------------------ 1020 1030 1040 1050 1060 1070 pF1KE2 PTQAHTTQPTPFKFNSNFKSNDGDFTFSSPQVVTQPPPAAYSNSESLLGLLTSDKPLQGD CCDS46 ------------------------------------------------------------ 1080 1090 1100 1110 1120 1130 pF1KE2 GYSGAKPIPGGQTIGPRNTFNFGSKNVSGISFTENMGSSQQKNSGFRRSDDMFTFHGPGK CCDS46 ------------------------------------------------------------ 1140 1150 1160 1170 1180 1190 pF1KE2 SVFGTPTLETANKNHETDGGSAHGDDDDDGPHFEPVVPLPDKIEVKTGEEDEEEFFCNRA CCDS46 ------------------------------------------------------------ 1200 1210 1220 1230 1240 1250 pF1KE2 KLFRFDVESKEWKERGIGNVKILRHKTSGKIRLLMRREQVLKICANHYISPDMKLTPNAG CCDS46 ------------------------------------------------------------ 1260 1270 1280 1290 1300 1310 pF1KE2 SDRSFVWHALDYADELPKPEQLAIRFKTPEEAALFKCKFEEAQSILKAPGTNVAMASNQA CCDS46 ------------------------------------------------------------ 1320 1330 1340 1350 1360 1370 pF1KE2 VRIVKEPTSHDNKDICKSDAGNLNFEFQVAKKEGSWWHCNSCSLKNASTAKKCVSCQNLN CCDS46 ------------------------------------------------------------ 1380 1390 1400 1410 1420 1430 pF1KE2 PSNKELVGPPLAETVFTPKTSPENVQDRFALVTPKKEGHWDCSICLVRNEPTVSRCIACQ CCDS46 ------------------------------------------------------------ 1440 1450 1460 1470 1480 1490 pF1KE2 NTKSANKSGSSFVHQASFKFGQGDLPKPINSDFRSVFSTKEGQWDCSACLVQNEGSSTKC CCDS46 ------------------------------------------------------------ 1500 1510 1520 1530 1540 1550 pF1KE2 AACQNPRKQSLPATSIPTPASFKFGTSETSKTLKSGFEDMFAKKEGQWDCSSCLVRNEAN CCDS46 ------------------------------------------------------------ 1560 1570 1580 1590 1600 1610 pF1KE2 ATRCVACQNPDKPSPSTSVPAPASFKFGTSETSKAPKSGFEGMFTKKEGQWDCSVCLVRN CCDS46 ------------------------------------------------------------ 1620 1630 1640 1650 1660 1670 pF1KE2 EASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNE CCDS46 ------------------------------------------------------------ 1680 1690 1700 1710 1720 1730 pF1KE2 ASATKCIACQNPGKQNQTTSAVSTPASSETSKAPKSGFEGMFTKKEGQWDCSVCLVRNEA CCDS46 ------------------------------------------------------------ 1740 1750 1760 1770 1780 1790 pF1KE2 SATKCIACQCPSKQNQTTAISTPASSEISKAPKSGFEGMFIRKGQWDCSVCCVQNESSSL CCDS46 ------------------------------------------------------------ 1800 1810 1820 1830 1840 1850 pF1KE2 KCVACDASKPTHKPIAEAPSAFTLGSEMKLHDSSGSQVGTGFKSNFSEKASKFGNTEQGF CCDS46 ------------------------------------------------------------ 1860 1870 1880 1890 1900 1910 pF1KE2 KFGHVDQENSPSFMFQGSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENG ::::::::::::::::::::::::::::::::::: :::::: CCDS46 -----------------SSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKREKPLEND 910 920 930 940 1920 1930 1940 1950 1960 1970 pF1KE2 TGFQAQDISGQKNGRGVIFGQTSSTFTFADLAKSTSGEGFQFGKKDPNFKGFSGAGEKLF ::.::::: :.:.:::::::::::::::::.::::::::::::::: ::::::::::::: CCDS46 TGLQAQDIRGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKKDLNFKGFSGAGEKLF 950 960 970 980 990 1000 1980 1990 2000 2010 2020 2030 pF1KE2 SSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEDEKVLYSQR ::.:::::::::::::::::::::::::::::::::::::::::::::::: ::::::: CCDS46 SSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQG 1010 1020 1030 1040 1050 1060 2040 2050 2060 2070 2080 2090 pF1KE2 VKLFRFDAEVSQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VKLFRFDAEVRQWKERGLGNLKILKNEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLS 1070 1080 1090 1100 1110 1120 2100 2110 2120 2130 2140 2150 pF1KE2 GSDRAWMWLASDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD :::::::: ::::::::::::.:::::::::::::::::::::::::::::::::::::: CCDS46 GSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVD 1130 1140 1150 1160 1170 1180 2160 2170 2180 2190 2200 2210 pF1KE2 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNPENTG :::::::::::::::::::::::::::::::::::::::::::.::::::::::: :::: CCDS46 TGRAAKLIQRAEEMKSGLKDFKTFLTNDQTKVTEEENKGSGTGVAGASDTTIKPNAENTG 1190 1200 1210 1220 1230 1240 2220 2230 2240 2250 2260 2270 pF1KE2 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFGESTTGFNFSFKSALSPSK ::::::::::::::::::::::::::::::::::::::::: ::::: ::::::::: :: CCDS46 PTLEWDNYDLREDALDDSVSSSSVHASPLASSPVRKNLFRFDESTTGSNFSFKSALSLSK 1250 1260 1270 1280 1290 1300 2280 2290 2300 2310 2320 2330 pF1KE2 SPAKLNQSGTSVGTDEESDVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAKL :::::::::::::::::: :::::::::::::::::::::::::::::::::::::::.. CCDS46 SPAKLNQSGTSVGTDEESVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEI 1310 1320 1330 1340 1350 1360 2340 2350 2360 2370 2380 2390 pF1KE2 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMTLQNMKGTE :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS46 YRYDKDVGQWKERGIGDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTE 1370 1380 1390 1400 1410 1420 2400 2410 2420 2430 2440 2450 pF1KE2 RVWLWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RVWVWTACDFADGERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTP 1430 1440 1450 1460 1470 1480 2460 2470 2480 2490 2500 2510 pF1KE2 RESPCGKIAVAVLEETTRERTDVIQGDDVADATSEVEVSSTSETTPKAVVSPPKFVFGSE ::::::::::::::: ::::::::::::::::.:::::::::::: ::::::::::: :: CCDS46 RESPCGKIAVAVLEEITRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFVSE 1490 1500 1510 1520 1530 1540 2520 2530 2540 2550 2560 2570 pF1KE2 SVKSIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SVKRIFSSEKSKPFAFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCEL 1550 1560 1570 1580 1590 1600 2580 2590 2600 2610 2620 2630 pF1KE2 SKNSDIEQSSDSKVKNLFASFPTEESSINYTFKTPEKAKEKKKPEDSPSDDDVLIVYELT ::::::::::::::::: ::::::::::::::::::: CCDS46 SKNSDIEQSSDSKVKNLSASFPTEESSINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTK 1610 1620 1630 1640 1650 1660 2640 2650 2660 2670 2680 2690 pF1KE2 PTAEQKALATKLKLPPTFFCYKNRPDYVSEEEEDDEDFETAVKKLNGKLYLDGSEKCRPL CCDS46 SADHLNGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLK 1670 1680 1690 1700 1710 1720 3224 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 18:19:52 2016 done: Sun Nov 6 18:19:54 2016 Total Scan time: 7.900 Total Display time: 2.070 Function used was FASTA [36.3.4 Apr, 2011]