FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2359, 387 aa 1>>>pF1KE2359 387 - 387 aa - 387 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6360+/-0.00103; mu= 14.8172+/- 0.061 mean_var=150.9625+/-61.619, 0's: 0 Z-trim(104.6): 317 B-trim: 992 in 2/47 Lambda= 0.104385 statistics sampled from 7478 (7987) to 7478 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.596), E-opt: 0.2 (0.245), width: 16 Scan time: 2.330 The best scores are: opt bits E(32554) CCDS34270.1 HTR4 gene_id:3360|Hs108|chr5 ( 387) 2628 408.5 5.1e-114 CCDS4291.1 HTR4 gene_id:3360|Hs108|chr5 ( 388) 2433 379.2 3.5e-105 CCDS34273.2 HTR4 gene_id:3360|Hs108|chr5 ( 360) 2431 378.8 4.2e-105 CCDS34272.1 HTR4 gene_id:3360|Hs108|chr5 ( 428) 2428 378.5 6.3e-105 CCDS34271.1 HTR4 gene_id:3360|Hs108|chr5 ( 378) 2420 377.2 1.4e-104 CCDS75353.1 HTR4 gene_id:3360|Hs108|chr5 ( 411) 2420 377.2 1.4e-104 CCDS4292.1 ADRB2 gene_id:154|Hs108|chr5 ( 413) 705 119.0 8e-27 CCDS6052.1 ADRA1A gene_id:148|Hs108|chr8 ( 429) 548 95.4 1.1e-19 CCDS6053.1 ADRA1A gene_id:148|Hs108|chr8 ( 455) 548 95.4 1.1e-19 CCDS6054.1 ADRA1A gene_id:148|Hs108|chr8 ( 466) 548 95.4 1.1e-19 CCDS34869.1 ADRA1A gene_id:148|Hs108|chr8 ( 475) 548 95.4 1.1e-19 CCDS197.1 HTR6 gene_id:3362|Hs108|chr1 ( 440) 543 94.6 1.8e-19 CCDS4395.1 HRH2 gene_id:3274|Hs108|chr5 ( 359) 520 91.0 1.8e-18 CCDS47344.1 HRH2 gene_id:3274|Hs108|chr5 ( 397) 520 91.1 1.9e-18 CCDS4393.1 DRD1 gene_id:1812|Hs108|chr5 ( 446) 520 91.2 2e-18 CCDS7586.1 ADRB1 gene_id:153|Hs108|chr10 ( 477) 486 86.1 7.4e-17 CCDS7410.1 HTR7 gene_id:3363|Hs108|chr10 ( 432) 469 83.5 4.1e-16 CCDS7409.1 HTR7 gene_id:3363|Hs108|chr10 ( 445) 469 83.5 4.2e-16 CCDS7408.1 HTR7 gene_id:3363|Hs108|chr10 ( 479) 469 83.5 4.4e-16 CCDS83269.1 ADRA1A gene_id:148|Hs108|chr8 ( 342) 448 80.2 3.2e-15 CCDS5936.1 HTR5A gene_id:3361|Hs108|chr7 ( 357) 446 79.9 4e-15 CCDS6099.1 ADRB3 gene_id:155|Hs108|chr8 ( 408) 440 79.1 8.2e-15 CCDS75520.1 TAAR9 gene_id:134860|Hs108|chr6 ( 348) 421 76.1 5.4e-14 CCDS1268.1 GPR161 gene_id:23432|Hs108|chr1 ( 529) 422 76.5 6.2e-14 CCDS72978.1 GPR161 gene_id:23432|Hs108|chr1 ( 546) 422 76.5 6.4e-14 CCDS58043.1 GPR161 gene_id:23432|Hs108|chr1 ( 549) 422 76.5 6.4e-14 CCDS5155.1 TAAR6 gene_id:319100|Hs108|chr6 ( 345) 418 75.6 7.4e-14 CCDS34168.1 HTR1A gene_id:3350|Hs108|chr5 ( 422) 409 74.4 2.1e-13 CCDS5154.1 TAAR8 gene_id:83551|Hs108|chr6 ( 342) 405 73.7 2.8e-13 CCDS5156.1 TAAR5 gene_id:9038|Hs108|chr6 ( 337) 395 72.2 8e-13 CCDS3405.1 DRD5 gene_id:1816|Hs108|chr4 ( 477) 396 72.5 8.9e-13 CCDS5036.1 GPR63 gene_id:81491|Hs108|chr6 ( 419) 381 70.2 3.9e-12 CCDS13079.1 ADRA1D gene_id:146|Hs108|chr20 ( 572) 371 68.9 1.3e-11 CCDS2920.1 HTR1F gene_id:3355|Hs108|chr3 ( 366) 366 67.8 1.7e-11 CCDS7569.2 ADRA2A gene_id:150|Hs108|chr10 ( 465) 365 67.8 2.2e-11 CCDS47004.1 ADRA2C gene_id:152|Hs108|chr4 ( 462) 356 66.5 5.7e-11 CCDS2066.1 GPR45 gene_id:11250|Hs108|chr2 ( 372) 353 65.9 6.8e-11 CCDS4347.1 ADRA1B gene_id:147|Hs108|chr5 ( 520) 352 65.9 9.2e-11 >>CCDS34270.1 HTR4 gene_id:3360|Hs108|chr5 (387 aa) initn: 2628 init1: 2628 opt: 2628 Z-score: 2160.5 bits: 408.5 E(32554): 5.1e-114 Smith-Waterman score: 2628; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KE2 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRY 310 320 330 340 350 360 370 380 pF1KE2 TVLHRGHHQELEKLPIHNDPESLESCF ::::::::::::::::::::::::::: CCDS34 TVLHRGHHQELEKLPIHNDPESLESCF 370 380 >>CCDS4291.1 HTR4 gene_id:3360|Hs108|chr5 (388 aa) initn: 2451 init1: 2429 opt: 2433 Z-score: 2001.7 bits: 379.2 E(32554): 3.5e-105 Smith-Waterman score: 2433; 95.8% identity (97.4% similar) in 380 aa overlap (1-380:1-379) 10 20 30 40 50 60 pF1KE2 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD 310 320 330 340 350 360 370 380 pF1KE2 TVLHRGHHQELEKLPIHNDPESLESCF .: . : . : . : ..: CCDS42 AV-ECGGQWESQCHPPATSPLVAAQPSDT 370 380 >>CCDS34273.2 HTR4 gene_id:3360|Hs108|chr5 (360 aa) initn: 2453 init1: 2431 opt: 2431 Z-score: 2000.5 bits: 378.8 E(32554): 4.2e-105 Smith-Waterman score: 2431; 99.7% identity (100.0% similar) in 360 aa overlap (1-360:1-360) 10 20 30 40 50 60 pF1KE2 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS34 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRF 310 320 330 340 350 360 370 380 pF1KE2 TVLHRGHHQELEKLPIHNDPESLESCF >>CCDS34272.1 HTR4 gene_id:3360|Hs108|chr5 (428 aa) initn: 2450 init1: 2428 opt: 2428 Z-score: 1997.2 bits: 378.5 E(32554): 6.3e-105 Smith-Waterman score: 2428; 99.2% identity (99.2% similar) in 363 aa overlap (1-363:1-363) 10 20 30 40 50 60 pF1KE2 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRT 310 320 330 340 350 360 370 380 pF1KE2 TVLHRGHHQELEKLPIHNDPESLESCF : CCDS34 DFLFDRDILARYWTKPARAGPFSGTLSIRCLTARKPVLGDAVECGGQWESQCHPPATSPL 370 380 390 400 410 420 >>CCDS34271.1 HTR4 gene_id:3360|Hs108|chr5 (378 aa) initn: 2420 init1: 2420 opt: 2420 Z-score: 1991.3 bits: 377.2 E(32554): 1.4e-104 Smith-Waterman score: 2420; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358) 10 20 30 40 50 60 pF1KE2 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLSG 310 320 330 340 350 360 370 380 pF1KE2 TVLHRGHHQELEKLPIHNDPESLESCF CCDS34 CSPVSSFLLLFCNRPVPV 370 >>CCDS75353.1 HTR4 gene_id:3360|Hs108|chr5 (411 aa) initn: 2420 init1: 2420 opt: 2420 Z-score: 1990.9 bits: 377.2 E(32554): 1.4e-104 Smith-Waterman score: 2420; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358) 10 20 30 40 50 60 pF1KE2 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 AICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLSS 310 320 330 340 350 360 370 380 pF1KE2 TVLHRGHHQELEKLPIHNDPESLESCF CCDS75 GTETDRKKLWNKEEKIDQTIQMPKRKRKKKASLSYEDLILLGRKSCFREGK 370 380 390 400 410 >>CCDS4292.1 ADRB2 gene_id:154|Hs108|chr5 (413 aa) initn: 589 init1: 254 opt: 705 Z-score: 595.1 bits: 119.0 E(32554): 8e-27 Smith-Waterman score: 708; 35.5% identity (63.7% similar) in 377 aa overlap (5-373:21-372) 10 20 30 40 pF1KE2 MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAV : .:..:. : : . .: ..: ..::.::..:. CCDS42 MGQPGNGSAFLLAPNGSHAPDHDVTQERD--EVWVVGMGIVMSLIVLAIVFGNVLVITAI 10 20 30 40 50 50 60 70 80 90 100 pF1KE2 CWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLT ..:. . :::::.::: :::.... :.:::: .... .: .:. .: ::.::: . CCDS42 AKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCV 60 70 80 90 100 110 110 120 130 140 150 160 pF1KE2 TASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNI :::: :: :..:::.:: .:. :.. .: . ... :.. . :::::.. : CCDS42 TASIETLCVIAVDRYFAIT-SPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRA 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE2 GIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAH ... .: .: : : :..:. :::. :.:.::.:...::..: :.. ::.. . CCDS42 -----THQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQ 180 190 200 210 220 230 230 240 250 260 270 pF1KE2 QIQMLQ-RAGASSESRPQSADQHSTHRMRT-------ETKAAKTLCIIMGCFCLCWAPFF .:. . : ... :. .. : .. : .: : :: ::: :::: : ::: ::: CCDS42 KIDKSEGRFHVQNLSQVEQ-DGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFF 240 250 260 270 280 290 280 290 300 310 320 330 pF1KE2 VTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRR ..::: . : . .:. . :.::.:::.::..: . .:: :: .:: :: CCDS42 IVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLC-----LRR 300 310 320 330 340 340 350 360 370 380 pF1KE2 PSILGQTVPCSTTTINGSTHVLRYTVLHRGHHQELEKLPIHNDPESLESCF :. . :. ::.: . :.: : :: CCDS42 SSLKAYGNGYSS---NGNTGE------QSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVP 350 360 370 380 390 CCDS42 SDNIDSQGRNCSTNDSLL 400 410 >>CCDS6052.1 ADRA1A gene_id:148|Hs108|chr8 (429 aa) initn: 541 init1: 212 opt: 548 Z-score: 467.1 bits: 95.4 E(32554): 1.1e-19 Smith-Waterman score: 598; 32.2% identity (61.2% similar) in 363 aa overlap (16-353:22-369) 10 20 30 40 50 pF1KE2 MDKLDANVSSEEGFGSVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKI .. :..:: ..:. .::...:::.::...: :.:... CCDS60 MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 KTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCC :.:.::.:: ::::.. :.::.:: : : .:.::: . ...::: ::::. :: CCDS60 -THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCI 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 ISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKR ::.::: .. :: : . .: : . : :.. ::. :.. :: . . : CCDS60 ISIDRYIGVS-YPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-GWRQPAPED----- 120 130 140 150 160 170 180 190 200 210 220 pF1KE2 KFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAH--------- : : . . :.. .. .::.:. .... : :.::.::.... CCDS60 -------ETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTD 180 190 200 210 220 230 240 250 260 270 pF1KE2 -----QIQM-LQRAGASSESRPQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCW :. . ..: .: . . ... . .:: .. : :::::: :..::: ::: CCDS60 KSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCW 230 240 250 260 270 280 280 290 300 310 320 pF1KE2 APFFVTNIVDPFIDYTVPGQ-VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL--CC :::.. . :. :.. :. .::::.:: .::..: .. :..:: .: : CCDS60 LPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 290 300 310 320 330 340 330 340 350 360 370 380 pF1KE2 DDERYRRPSILGQTVPCSTTTINGSTHVLRYTVLHRGHHQELEKLPIHNDPESLESCF .. :: :. . ...: CCDS60 LCRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPR 350 360 370 380 390 400 >>CCDS6053.1 ADRA1A gene_id:148|Hs108|chr8 (455 aa) initn: 541 init1: 212 opt: 548 Z-score: 466.8 bits: 95.4 E(32554): 1.1e-19 Smith-Waterman score: 598; 32.2% identity (61.2% similar) in 363 aa overlap (16-353:22-369) 10 20 30 40 50 pF1KE2 MDKLDANVSSEEGFGSVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKI .. :..:: ..:. .::...:::.::...: :.:... CCDS60 MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 KTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCC :.:.::.:: ::::.. :.::.:: : : .:.::: . ...::: ::::. :: CCDS60 -THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCI 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 ISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKR ::.::: .. :: : . .: : . : :.. ::. :.. :: . . : CCDS60 ISIDRYIGVS-YPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-GWRQPAPED----- 120 130 140 150 160 170 180 190 200 210 220 pF1KE2 KFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAH--------- : : . . :.. .. .::.:. .... : :.::.::.... CCDS60 -------ETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTD 180 190 200 210 220 230 240 250 260 270 pF1KE2 -----QIQM-LQRAGASSESRPQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCW :. . ..: .: . . ... . .:: .. : :::::: :..::: ::: CCDS60 KSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCW 230 240 250 260 270 280 280 290 300 310 320 pF1KE2 APFFVTNIVDPFIDYTVPGQ-VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL--CC :::.. . :. :.. :. .::::.:: .::..: .. :..:: .: : CCDS60 LPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 290 300 310 320 330 340 330 340 350 360 370 380 pF1KE2 DDERYRRPSILGQTVPCSTTTINGSTHVLRYTVLHRGHHQELEKLPIHNDPESLESCF .. :: :. . ...: CCDS60 LCRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPR 350 360 370 380 390 400 >>CCDS6054.1 ADRA1A gene_id:148|Hs108|chr8 (466 aa) initn: 541 init1: 212 opt: 548 Z-score: 466.7 bits: 95.4 E(32554): 1.1e-19 Smith-Waterman score: 598; 32.2% identity (61.2% similar) in 363 aa overlap (16-353:22-369) 10 20 30 40 50 pF1KE2 MDKLDANVSSEEGFGSVEKVVLL-TFLSTVILMAILGNLLVMVAVCWDRQLRKI .. :..:: ..:. .::...:::.::...: :.:... CCDS60 MVFLSGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 KTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCC :.:.::.:: ::::.. :.::.:: : : .:.::: . ...::: ::::. :: CCDS60 -THYYIVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCI 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 ISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKR ::.::: .. :: : . .: : . : :.. ::. :.. :: . . : CCDS60 ISIDRYIGVS-YPLRYPTIVTQRRGLMALLCVWALSLVISIGPLF-GWRQPAPED----- 120 130 140 150 160 170 180 190 200 210 220 pF1KE2 KFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAH--------- : : . . :.. .. .::.:. .... : :.::.::.... CCDS60 -------ETICQINEEPGYVLFSALGSFYLPLAIILVMYCRVYVVAKRESRGLKSGLKTD 180 190 200 210 220 230 240 250 260 270 pF1KE2 -----QIQM-LQRAGASSESRPQSADQHSTH------RMRTETKAAKTLCIIMGCFCLCW :. . ..: .: . . ... . .:: .. : :::::: :..::: ::: CCDS60 KSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCW 230 240 250 260 270 280 280 290 300 310 320 pF1KE2 APFFVTNIVDPFIDYTVPGQ-VWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL--CC :::.. . :. :.. :. .::::.:: .::..: .. :..:: .: : CCDS60 LPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQC 290 300 310 320 330 340 330 340 350 360 370 380 pF1KE2 DDERYRRPSILGQTVPCSTTTINGSTHVLRYTVLHRGHHQELEKLPIHNDPESLESCF .. :: :. . ...: CCDS60 LCRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFFSSMPR 350 360 370 380 390 400 387 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 17:06:05 2016 done: Sun Nov 6 17:06:05 2016 Total Scan time: 2.330 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]