FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2365, 243 aa 1>>>pF1KE2365 243 - 243 aa - 243 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5977+/-0.000338; mu= 13.2675+/- 0.021 mean_var=84.7374+/-17.082, 0's: 0 Z-trim(115.9): 55 B-trim: 1498 in 1/55 Lambda= 0.139327 statistics sampled from 26621 (26676) to 26621 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.313), width: 16 Scan time: 7.060 The best scores are: opt bits E(85289) NP_757362 (OMIM: 186730) T-cell surface glycoprote ( 243) 1619 334.9 7.5e-92 NP_004922 (OMIM: 186730) T-cell surface glycoprote ( 210) 1367 284.2 1.2e-76 NP_742099 (OMIM: 186730) T-cell surface glycoprote ( 221) 1367 284.3 1.2e-76 XP_011531466 (OMIM: 186730) PREDICTED: T-cell surf ( 246) 1367 284.3 1.3e-76 NP_001171571 (OMIM: 186730) T-cell surface glycopr ( 198) 1089 228.3 7.5e-60 NP_742100 (OMIM: 186730) T-cell surface glycoprote ( 213) 1089 228.4 7.9e-60 >>NP_757362 (OMIM: 186730) T-cell surface glycoprotein C (243 aa) initn: 1619 init1: 1619 opt: 1619 Z-score: 1770.0 bits: 334.9 E(85289): 7.5e-92 Smith-Waterman score: 1619; 100.0% identity (100.0% similar) in 243 aa overlap (1-243:1-243) 10 20 30 40 50 60 pF1KE2 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_757 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_757 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_757 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LVLLVSLGVAIHLCCRRRRARLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_757 LVLLVSLGVAIHLCCRRRRARLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWI 190 200 210 220 230 240 pF1KE2 LKT ::: NP_757 LKT >>NP_004922 (OMIM: 186730) T-cell surface glycoprotein C (210 aa) initn: 1367 init1: 1367 opt: 1367 Z-score: 1497.1 bits: 284.2 E(85289): 1.2e-76 Smith-Waterman score: 1367; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207) 10 20 30 40 50 60 pF1KE2 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LVLLVSLGVAIHLCCRRRRARLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWI ::::::::::::::::::::::::::: NP_004 LVLLVSLGVAIHLCCRRRRARLRFMKQFYK 190 200 210 >>NP_742099 (OMIM: 186730) T-cell surface glycoprotein C (221 aa) initn: 1367 init1: 1367 opt: 1367 Z-score: 1496.8 bits: 284.3 E(85289): 1.2e-76 Smith-Waterman score: 1367; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207) 10 20 30 40 50 60 pF1KE2 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LVLLVSLGVAIHLCCRRRRARLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWI ::::::::::::::::::::::::::: NP_742 LVLLVSLGVAIHLCCRRRRARLRFMKQLRLHPLEKCSRMDY 190 200 210 220 >>XP_011531466 (OMIM: 186730) PREDICTED: T-cell surface (246 aa) initn: 1367 init1: 1367 opt: 1367 Z-score: 1496.2 bits: 284.3 E(85289): 1.3e-76 Smith-Waterman score: 1367; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207) 10 20 30 40 50 60 pF1KE2 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LVLLVSLGVAIHLCCRRRRARLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWI ::::::::::::::::::::::::::: XP_011 LVLLVSLGVAIHLCCRRRRARLRFMKQKFNIVCLKISGFTTCCCFQILQMSREYGFGVLL 190 200 210 220 230 240 >>NP_001171571 (OMIM: 186730) T-cell surface glycoprotei (198 aa) initn: 1089 init1: 1089 opt: 1089 Z-score: 1195.5 bits: 228.3 E(85289): 7.5e-60 Smith-Waterman score: 1089; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165) 10 20 30 40 50 60 pF1KE2 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV ::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGLKGKVYQEPLSPNAC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LVLLVSLGVAIHLCCRRRRARLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWI NP_001 MDTTAILQPHRSCLTHGS 190 >>NP_742100 (OMIM: 186730) T-cell surface glycoprotein C (213 aa) initn: 1407 init1: 1089 opt: 1089 Z-score: 1195.1 bits: 228.4 E(85289): 7.9e-60 Smith-Waterman score: 1351; 87.7% identity (87.7% similar) in 243 aa overlap (1-243:1-213) 10 20 30 40 50 60 pF1KE2 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMRIYWLRQRQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 PSSDSHHEFLALWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPITLGLLVAGV ::::::::::::::::::::::::::::::::::::::::::::: NP_742 SPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKG--------------- 130 140 150 160 190 200 210 220 230 240 pF1KE2 LVLLVSLGVAIHLCCRRRRARLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWI ::::::::::::::::::::::::::::::::::::::::::::: NP_742 ---------------RRRRARLRFMKQPQGEGISGTFVPQCLHGYYSNTTTSQKLLNPWI 170 180 190 200 210 pF1KE2 LKT ::: NP_742 LKT 243 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 18:23:57 2016 done: Sun Nov 6 18:23:58 2016 Total Scan time: 7.060 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]