FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2374, 284 aa 1>>>pF1KE2374 284 - 284 aa - 284 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3410+/-0.000734; mu= 14.7295+/- 0.044 mean_var=58.9662+/-11.700, 0's: 0 Z-trim(108.4): 8 B-trim: 0 in 0/53 Lambda= 0.167022 statistics sampled from 10190 (10195) to 10190 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.313), width: 16 Scan time: 2.160 The best scores are: opt bits E(32554) CCDS13860.1 NIPSNAP1 gene_id:8508|Hs108|chr22 ( 284) 1970 482.7 1.3e-136 CCDS5521.1 GBAS gene_id:2631|Hs108|chr7 ( 286) 1383 341.2 5e-94 CCDS56488.1 GBAS gene_id:2631|Hs108|chr7 ( 247) 791 198.6 3.8e-51 CCDS6761.1 NIPSNAP3B gene_id:55335|Hs108|chr9 ( 247) 257 69.9 2.1e-12 >>CCDS13860.1 NIPSNAP1 gene_id:8508|Hs108|chr22 (284 aa) initn: 1970 init1: 1970 opt: 1970 Z-score: 2566.0 bits: 482.7 E(32554): 1.3e-136 Smith-Waterman score: 1970; 100.0% identity (100.0% similar) in 284 aa overlap (1-284:1-284) 10 20 30 40 50 60 pF1KE2 MAPRLCSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MAPRLCSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TLLSKKETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TLLSKKETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 QAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 GPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 GPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDL 190 200 210 220 230 240 250 260 270 280 pF1KE2 QSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ :::::::::::::::::::::::::::::::::::::::::::: CCDS13 QSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ 250 260 270 280 >>CCDS5521.1 GBAS gene_id:2631|Hs108|chr7 (286 aa) initn: 1383 init1: 1383 opt: 1383 Z-score: 1801.6 bits: 341.2 E(32554): 5e-94 Smith-Waterman score: 1383; 75.5% identity (93.2% similar) in 249 aa overlap (36-284:38-286) 10 20 30 40 50 60 pF1KE2 CSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSK ... : ::..::::.::::::::::.::.: CCDS55 ARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHL ::::::::.:::::::: :.:::.. . ::::.: :. :::.:::.:::::::::::::: CCDS55 KETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGEQDQAVHL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 WRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPNIY ::. :::::: . ::::..:::.::::. ::.:::::.::::::::::::: :: ::::: CCDS55 WRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 ELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREE :::.:.:.::::::::: :::::..::...:::::::::::.::.:::::::.:::.::. CCDS55 ELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTRED 190 200 210 220 230 240 250 260 270 280 pF1KE2 TRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ :::::.:.::.: :::::::...:::::::::: :::: CCDS55 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ 250 260 270 280 >>CCDS56488.1 GBAS gene_id:2631|Hs108|chr7 (247 aa) initn: 984 init1: 791 opt: 791 Z-score: 1031.6 bits: 198.6 E(32554): 3.8e-51 Smith-Waterman score: 923; 58.6% identity (75.1% similar) in 249 aa overlap (36-284:38-247) 10 20 30 40 50 60 pF1KE2 CSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSK ... : ::..::::.::::::::::.::.: CCDS56 ARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHL ::::::::.::. .. ..: :: :.: .. CCDS56 KETSNLYKLQFKRCCQRFTKINTTL---VL-------------------WWGLGTRG--- 70 80 90 100 130 140 150 160 170 180 pF1KE2 WRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPNIY : .:: :.::::. ::.:::::.::::::::::::: :: ::::: CCDS56 ----------MASRTKL----EFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIY 110 120 130 140 190 200 210 220 230 240 pF1KE2 ELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREE :::.:.:.::::::::: :::::..::...:::::::::::.::.:::::::.:::.::. CCDS56 ELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYRDLQTRED 150 160 170 180 190 200 250 260 270 280 pF1KE2 TRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ :::::.:.::.: :::::::...:::::::::: :::: CCDS56 IRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ 210 220 230 240 >>CCDS6761.1 NIPSNAP3B gene_id:55335|Hs108|chr9 (247 aa) initn: 196 init1: 99 opt: 257 Z-score: 336.2 bits: 69.9 E(32554): 2.1e-12 Smith-Waterman score: 257; 25.8% identity (58.1% similar) in 229 aa overlap (65-284:30-247) 40 50 60 70 80 90 pF1KE2 YSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPEYLDAYNSLTEAV .. ...:... . .:: ..:. : . CCDS67 MLVLRSGLTKALASRTLAPQVCSSFATGPRQYDGTFYEFRTYYLKPSNMNAF---MENL 10 20 30 40 50 100 110 120 130 140 150 pF1KE2 LPKLHLDEDYPCSLVGNWNTWYG-EQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRR ..:: .: ::: :.. .: . ... :.:.... . . . : : ::. . CCDS67 KKNIHLRTSYS-ELVGFWSVEFGGRTNKVFHIWKYDN-FAHRAEVRKALANCKEW----Q 60 70 80 90 100 110 160 170 180 190 200 pF1KE2 ERSQML-LSRRNQLLLEFSF---WN--EPQPRMGPNIYELRTYKLKPGTMIEWGNNWARA :.: . :.: .. :... :. : :. : .::: ....::: ::. . :: CCDS67 EQSIIPNLARIDKQETEITYLIPWSKLEKPPKEG--VYELAVFQMKPGGPALWGDAFERA 120 130 140 150 160 210 220 230 240 250 260 pF1KE2 IKYRQE--NQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVP :. . . ..:: : .. ::: :: :: .. .:: :. . . : .: CCDS67 INAHVNLGYTKVVGVFHTEYGELNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVN 170 180 190 200 210 220 270 280 pF1KE2 LVRHMESRIMIPLKISPLQ . ... ..:: ..:::. CCDS67 YLVSQQNMLLIPASFSPLK 230 240 284 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 12:56:17 2016 done: Sun Nov 6 12:56:17 2016 Total Scan time: 2.160 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]