FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2398, 338 aa 1>>>pF1KE2398 338 - 338 aa - 338 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1123+/-0.000412; mu= 17.4484+/- 0.026 mean_var=67.5730+/-13.889, 0's: 0 Z-trim(111.6): 262 B-trim: 0 in 0/52 Lambda= 0.156023 statistics sampled from 19961 (20242) to 19961 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.237), width: 16 Scan time: 6.840 The best scores are: opt bits E(85289) NP_057696 (OMIM: 610387) mitoferrin-1 isoform 1 [H ( 338) 2231 511.3 1.2e-144 XP_011542852 (OMIM: 610387) PREDICTED: mitoferrin- ( 272) 1782 410.1 2.7e-114 XP_011542855 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 1767 406.8 2.8e-113 XP_016869021 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 1767 406.8 2.8e-113 XP_006716415 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 1767 406.8 2.8e-113 NP_001304743 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 1767 406.8 2.8e-113 NP_001304742 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 1767 406.8 2.8e-113 NP_112489 (OMIM: 609767) mitoferrin-2 [Homo sapien ( 364) 1499 346.5 5.1e-95 XP_011538541 (OMIM: 609767) PREDICTED: mitoferrin- ( 274) 1316 305.2 1e-82 XP_005270265 (OMIM: 609767) PREDICTED: mitoferrin- ( 265) 1299 301.4 1.4e-81 XP_006718068 (OMIM: 609767) PREDICTED: mitoferrin- ( 265) 1299 301.4 1.4e-81 XP_016872230 (OMIM: 609767) PREDICTED: mitoferrin- ( 265) 1299 301.4 1.4e-81 XP_005270268 (OMIM: 609767) PREDICTED: mitoferrin- ( 265) 1299 301.4 1.4e-81 XP_011538542 (OMIM: 609767) PREDICTED: mitoferrin- ( 265) 1299 301.4 1.4e-81 XP_011542856 (OMIM: 610387) PREDICTED: mitoferrin- ( 187) 1221 283.7 2.1e-76 NP_001304741 (OMIM: 610387) mitoferrin-1 isoform 2 ( 187) 1221 283.7 2.1e-76 XP_016872231 (OMIM: 609767) PREDICTED: mitoferrin- ( 209) 944 221.4 1.3e-57 XP_006718069 (OMIM: 609767) PREDICTED: mitoferrin- ( 193) 655 156.4 4.8e-38 XP_011538546 (OMIM: 609767) PREDICTED: mitoferrin- ( 196) 655 156.4 4.8e-38 XP_011526228 (OMIM: 610822) PREDICTED: solute carr ( 306) 377 93.9 4.7e-19 NP_775908 (OMIM: 610822) solute carrier family 25 ( 370) 377 94.0 5.5e-19 NP_001137252 (OMIM: 610820) solute carrier family ( 359) 359 89.9 8.9e-18 NP_060625 (OMIM: 616149) solute carrier family 25 ( 310) 349 87.6 3.8e-17 NP_001308169 (OMIM: 610820) solute carrier family ( 336) 348 87.4 4.7e-17 NP_057100 (OMIM: 610820) solute carrier family 25 ( 351) 348 87.4 4.9e-17 NP_001098117 (OMIM: 616149) solute carrier family ( 311) 346 86.9 6e-17 NP_001164641 (OMIM: 607571) mitochondrial 2-oxodic ( 298) 312 79.3 1.2e-14 NP_085134 (OMIM: 607571) mitochondrial 2-oxodicarb ( 299) 312 79.3 1.2e-14 NP_061331 (OMIM: 610821) solute carrier family 25 ( 338) 309 78.6 2.1e-14 XP_011526586 (OMIM: 608746) PREDICTED: calcium-bin ( 469) 307 78.3 3.7e-14 XP_016882777 (OMIM: 608746) PREDICTED: calcium-bin ( 484) 307 78.3 3.8e-14 XP_011526585 (OMIM: 608746) PREDICTED: calcium-bin ( 490) 307 78.3 3.8e-14 XP_011526584 (OMIM: 608746) PREDICTED: calcium-bin ( 503) 307 78.3 3.9e-14 XP_011526582 (OMIM: 608746) PREDICTED: calcium-bin ( 531) 307 78.3 4.1e-14 XP_016880226 (OMIM: 610820) PREDICTED: solute carr ( 258) 301 76.8 5.8e-14 NP_001308227 (OMIM: 610822) solute carrier family ( 232) 298 76.0 8.6e-14 NP_001243463 (OMIM: 190315,615182) tricarboxylate ( 318) 279 71.9 2.1e-12 NP_005975 (OMIM: 190315,615182) tricarboxylate tra ( 311) 278 71.6 2.4e-12 XP_005257618 (OMIM: 606521,607196,613710) PREDICTE ( 320) 267 69.2 1.4e-11 XP_005257617 (OMIM: 606521,607196,613710) PREDICTE ( 320) 267 69.2 1.4e-11 XP_005257616 (OMIM: 606521,607196,613710) PREDICTE ( 320) 267 69.2 1.4e-11 NP_001119593 (OMIM: 606521,607196,613710) mitochon ( 320) 267 69.2 1.4e-11 XP_016880415 (OMIM: 606521,607196,613710) PREDICTE ( 320) 267 69.2 1.4e-11 NP_068380 (OMIM: 606521,607196,613710) mitochondri ( 320) 267 69.2 1.4e-11 XP_006722070 (OMIM: 606521,607196,613710) PREDICTE ( 320) 267 69.2 1.4e-11 NP_001119594 (OMIM: 606521,607196,613710) mitochon ( 320) 267 69.2 1.4e-11 XP_005257619 (OMIM: 606521,607196,613710) PREDICTE ( 320) 267 69.2 1.4e-11 XP_011523182 (OMIM: 610820) PREDICTED: solute carr ( 365) 266 69.0 1.8e-11 XP_011523400 (OMIM: 606521,607196,613710) PREDICTE ( 215) 260 67.5 3e-11 XP_016880417 (OMIM: 606521,607196,613710) PREDICTE ( 215) 260 67.5 3e-11 >>NP_057696 (OMIM: 610387) mitoferrin-1 isoform 1 [Homo (338 aa) initn: 2231 init1: 2231 opt: 2231 Z-score: 2717.8 bits: 511.3 E(85289): 1.2e-144 Smith-Waterman score: 2231; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338) 10 20 30 40 50 60 pF1KE2 MELRSGSVGSQAVARRMDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MELRSGSVGSQAVARRMDGDSRDGGGGKDATGSEDYENLPTSASVSTHMTAGAMAGILEH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 SVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 SVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 AISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTYNPQSHIIS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 GGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFK 250 260 270 280 290 300 310 320 330 pF1KE2 GIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY :::::::::::::::::::::::::::::::::::::: NP_057 GIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 310 320 330 >>XP_011542852 (OMIM: 610387) PREDICTED: mitoferrin-1 is (272 aa) initn: 1782 init1: 1782 opt: 1782 Z-score: 2172.9 bits: 410.1 E(85289): 2.7e-114 Smith-Waterman score: 1782; 99.3% identity (100.0% similar) in 270 aa overlap (69-338:3-272) 40 50 60 70 80 90 pF1KE2 LPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTE ..:::::::::::::::::::::::::::: XP_011 MGLQTRMQSLSPDPKAQYTSIYGALKKIMRTE 10 20 30 100 110 120 130 140 150 pF1KE2 GFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHD 40 50 60 70 80 90 160 170 180 190 200 210 pF1KE2 AVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFIT 100 110 120 130 140 150 220 230 240 250 260 270 pF1KE2 YEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR 160 170 180 190 200 210 280 290 300 310 320 330 pF1KE2 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 270 >>XP_011542855 (OMIM: 610387) PREDICTED: mitoferrin-1 is (266 aa) initn: 1767 init1: 1767 opt: 1767 Z-score: 2154.8 bits: 406.8 E(85289): 2.8e-113 Smith-Waterman score: 1767; 100.0% identity (100.0% similar) in 266 aa overlap (73-338:1-266) 50 60 70 80 90 100 pF1KE2 ASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWR :::::::::::::::::::::::::::::: XP_011 MQSLSPDPKAQYTSIYGALKKIMRTEGFWR 10 20 30 110 120 130 140 150 160 pF1KE2 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE2 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE2 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM 160 170 180 190 200 210 290 300 310 320 330 pF1KE2 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 >>XP_016869021 (OMIM: 610387) PREDICTED: mitoferrin-1 is (266 aa) initn: 1767 init1: 1767 opt: 1767 Z-score: 2154.8 bits: 406.8 E(85289): 2.8e-113 Smith-Waterman score: 1767; 100.0% identity (100.0% similar) in 266 aa overlap (73-338:1-266) 50 60 70 80 90 100 pF1KE2 ASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWR :::::::::::::::::::::::::::::: XP_016 MQSLSPDPKAQYTSIYGALKKIMRTEGFWR 10 20 30 110 120 130 140 150 160 pF1KE2 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE2 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE2 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM 160 170 180 190 200 210 290 300 310 320 330 pF1KE2 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 >>XP_006716415 (OMIM: 610387) PREDICTED: mitoferrin-1 is (266 aa) initn: 1767 init1: 1767 opt: 1767 Z-score: 2154.8 bits: 406.8 E(85289): 2.8e-113 Smith-Waterman score: 1767; 100.0% identity (100.0% similar) in 266 aa overlap (73-338:1-266) 50 60 70 80 90 100 pF1KE2 ASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWR :::::::::::::::::::::::::::::: XP_006 MQSLSPDPKAQYTSIYGALKKIMRTEGFWR 10 20 30 110 120 130 140 150 160 pF1KE2 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE2 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE2 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM 160 170 180 190 200 210 290 300 310 320 330 pF1KE2 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 >>NP_001304743 (OMIM: 610387) mitoferrin-1 isoform 3 [Ho (266 aa) initn: 1767 init1: 1767 opt: 1767 Z-score: 2154.8 bits: 406.8 E(85289): 2.8e-113 Smith-Waterman score: 1767; 100.0% identity (100.0% similar) in 266 aa overlap (73-338:1-266) 50 60 70 80 90 100 pF1KE2 ASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWR :::::::::::::::::::::::::::::: NP_001 MQSLSPDPKAQYTSIYGALKKIMRTEGFWR 10 20 30 110 120 130 140 150 160 pF1KE2 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE2 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE2 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM 160 170 180 190 200 210 290 300 310 320 330 pF1KE2 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 >>NP_001304742 (OMIM: 610387) mitoferrin-1 isoform 3 [Ho (266 aa) initn: 1767 init1: 1767 opt: 1767 Z-score: 2154.8 bits: 406.8 E(85289): 2.8e-113 Smith-Waterman score: 1767; 100.0% identity (100.0% similar) in 266 aa overlap (73-338:1-266) 50 60 70 80 90 100 pF1KE2 ASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWR :::::::::::::::::::::::::::::: NP_001 MQSLSPDPKAQYTSIYGALKKIMRTEGFWR 10 20 30 110 120 130 140 150 160 pF1KE2 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE2 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE2 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM 160 170 180 190 200 210 290 300 310 320 330 pF1KE2 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY 220 230 240 250 260 >>NP_112489 (OMIM: 609767) mitoferrin-2 [Homo sapiens] (364 aa) initn: 1580 init1: 1191 opt: 1499 Z-score: 1826.9 bits: 346.5 E(85289): 5.1e-95 Smith-Waterman score: 1503; 66.5% identity (87.8% similar) in 328 aa overlap (19-336:36-362) 10 20 30 pF1KE2 MELRSGSVGSQAVARRMDGDSRDGGGG----------KDATGSEDYEN : .: .::: .: .. ::: NP_112 RGAGGVAGGPAAGPGRSPGESALLDGWLQRGVGRGAGGGEAGACRPPVRQDPDSGPDYEA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE2 LPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTE ::..:.:.:::.:::.:::::: ::::.: ::::::::.::: :.: .. :: .:.::: NP_112 LPAGATVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQPDPAARYRNVLEALWRIIRTE 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE2 GFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHD :.:::.::.:: :::::::.::::::..:.::.::.: ::::.::: :: .:::::: NP_112 GLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGAAGCVATLLHD 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE2 AVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFIT :.::::::::::.::::: .. . .:.:.::..:: ::::::::::::::.:::.:::.: NP_112 AAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMT 190 200 210 220 230 240 220 230 240 250 260 270 pF1KE2 YEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR ::::::. ::.: :::.::..::. :::.:::::::::::::::::::..::. ..:.:. NP_112 YEFLQEHFNPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALN-SHITGH 250 260 270 280 290 300 280 290 300 310 320 330 pF1KE2 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY ..:::.:::::::..:...::.:.:::::::.:::::.:::::::::..:::: : :: NP_112 ITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWRAGK 310 320 330 340 350 360 >>XP_011538541 (OMIM: 609767) PREDICTED: mitoferrin-2 is (274 aa) initn: 1367 init1: 1010 opt: 1316 Z-score: 1606.0 bits: 305.2 E(85289): 1e-82 Smith-Waterman score: 1316; 68.9% identity (90.8% similar) in 273 aa overlap (64-336:3-272) 40 50 60 70 80 90 pF1KE2 EDYENLPTSASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKK :: ..::::::.::: :.: .. :: . XP_011 MGYP--EAQTRMQSLQPDPAARYRNVLEALWR 10 20 30 100 110 120 130 140 150 pF1KE2 IMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMA :.::::.:::.::.:: :::::::.::::::..:.::.::.: ::::.::: :: .: XP_011 IIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGAAGCVA 40 50 60 70 80 90 160 170 180 190 200 210 pF1KE2 TLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQS ::::::.::::::::::.::::: .. . .:.:.::..:: ::::::::::::::.:::. XP_011 TLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQA 100 110 120 130 140 150 220 230 240 250 260 270 pF1KE2 IHFITYEFLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLA :::.:::::::. ::.: :::.::..::. :::.:::::::::::::::::::..::. . XP_011 IHFMTYEFLQEHFNPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALN-S 160 170 180 190 200 280 290 300 310 320 330 pF1KE2 NISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLE .:.:...:::.:::::::..:...::.:.:::::::.:::::.:::::::::..:::: : XP_011 HITGHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEE 210 220 230 240 250 260 pF1KE2 NRAPY :: XP_011 WRAGK 270 >>XP_005270265 (OMIM: 609767) PREDICTED: mitoferrin-2 is (265 aa) initn: 1355 init1: 998 opt: 1299 Z-score: 1585.5 bits: 301.4 E(85289): 1.4e-81 Smith-Waterman score: 1299; 69.7% identity (91.7% similar) in 264 aa overlap (73-336:1-263) 50 60 70 80 90 100 pF1KE2 ASVSTHMTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWR ::::.::: :.: .. :: .:.::::.:: XP_005 MQSLQPDPAARYRNVLEALWRIIRTEGLWR 10 20 30 110 120 130 140 150 160 pF1KE2 PLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMN :.::.:: :::::::.::::::..:.::.::.: ::::.::: :: .:::::::.:: XP_005 PMRGLNVTATGAGPAHALYFACYEKLKKTLSDVIHPGGNSHIANGAAGCVATLLHDAAMN 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE2 PAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFL ::::::::.::::: .. . .:.:.::..:: ::::::::::::::.:::.:::.::::: XP_005 PAEVVKQRMQMYNSPYHRVTDCVRAVWQNEGAGAFYRSYTTQLTMNVPFQAIHFMTYEFL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE2 QEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGM ::. ::.: :::.::..::. :::.:::::::::::::::::::..::. ..:.:...:: XP_005 QEHFNPQRRYNPSSHVLSGACAGAVAAAATTPLDVCKTLLNTQESLALN-SHITGHITGM 160 170 180 190 200 290 300 310 320 330 pF1KE2 ANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY :.:::::::..:...::.:.:::::::.:::::.:::::::::..:::: : :: XP_005 ASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEEWRAGK 210 220 230 240 250 260 338 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 09:23:45 2016 done: Sun Nov 6 09:23:46 2016 Total Scan time: 6.840 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]