FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2400, 699 aa 1>>>pF1KE2400 699 - 699 aa - 699 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0471+/-0.00112; mu= 14.9689+/- 0.067 mean_var=59.8743+/-11.994, 0's: 0 Z-trim(101.1): 25 B-trim: 42 in 1/46 Lambda= 0.165750 statistics sampled from 6464 (6472) to 6464 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.544), E-opt: 0.2 (0.194), width: 16 Scan time: 1.530 The best scores are: opt bits E(33420) CCDS58713.1 GFPT1 gene_id:2673|Hs109|chr2 ( 699) 4598 1108.6 0 CCDS33216.1 GFPT1 gene_id:2673|Hs109|chr2 ( 681) 2954 715.4 6.8e-206 CCDS43411.1 GFPT2 gene_id:9945|Hs109|chr5 ( 682) 2443 593.2 4.2e-169 >>CCDS58713.1 GFPT1 gene_id:2673|Hs109|chr2 (699 aa) initn: 4598 init1: 4598 opt: 4598 Z-score: 5934.5 bits: 1108.6 E(33420): 0 Smith-Waterman score: 4598; 100.0% identity (100.0% similar) in 699 aa overlap (1-699:1-699) 10 20 30 40 50 60 pF1KE2 MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 IHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 GSQGERGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GSQGERGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 AVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 RVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELAS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 DFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 HINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLS 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 MDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLAL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 VDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVD 610 620 630 640 650 660 670 680 690 pF1KE2 CLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE ::::::::::::::::::::::::::::::::::::::: CCDS58 CLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE 670 680 690 >>CCDS33216.1 GFPT1 gene_id:2673|Hs109|chr2 (681 aa) initn: 2954 init1: 2954 opt: 2954 Z-score: 3810.1 bits: 715.4 E(33420): 6.8e-206 Smith-Waterman score: 4428; 97.4% identity (97.4% similar) in 699 aa overlap (1-699:1-681) 10 20 30 40 50 60 pF1KE2 MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 KKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 KKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 IHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 IHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 LEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRW :::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 LEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRT------------ 190 200 210 220 250 260 270 280 290 300 pF1KE2 GSQGERGKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVA :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 ------GKDKKGSCNLSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDDVA 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE2 AVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 AVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTMRG 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE2 RVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 RVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVELAS 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE2 DFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 DFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDCGV 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE2 HINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 HINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEVLS 470 480 490 500 510 520 550 560 570 580 590 600 pF1KE2 MDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPLAL 530 540 550 560 570 580 610 620 630 640 650 660 pF1KE2 VDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 VDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHSVD 590 600 610 620 630 640 670 680 690 pF1KE2 CLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE ::::::::::::::::::::::::::::::::::::::: CCDS33 CLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE 650 660 670 680 >>CCDS43411.1 GFPT2 gene_id:9945|Hs109|chr5 (682 aa) initn: 3641 init1: 2441 opt: 2443 Z-score: 3149.7 bits: 593.2 E(33420): 4.2e-169 Smith-Waterman score: 3611; 77.3% identity (92.4% similar) in 701 aa overlap (1-699:1-682) 10 20 30 40 50 60 pF1KE2 MCGIFAYLNYHVPRTRREILETLIKGLQRLEYRGYDSAGVGFDGGNDKDWEANACKIQLI :::::::.::.:::::.::.::::::::::::::::::::..::.: :.. .:::. CCDS43 MCGIFAYMNYRVPRTRKEIFETLIKGLQRLEYRGYDSAGVAIDGNNH---EVKERHIQLV 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 KKKGKVKALDEEVHKQQDMDLDIEFDVHLGIAHTRWATHGEPSPVNSHPQRSDKNNEFIV ::.:::::::::..::..::: .::..:.::::::::::: :: ::::::::::.:::.: CCDS43 KKRGKVKALDEELYKQDSMDLKVEFETHFGIAHTRWATHGVPSAVNSHPQRSDKGNEFVV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 IHNGIITNYKDLKKFLESKGYDFESETDTETIAKLVKYMYDNRESQDTSFTTLVERVIQQ ::::::::::::.::::::::.:::::::::::::.::..::::..: .:.::::::::: CCDS43 IHNGIITNYKDLRKFLESKGYEFESETDTETIAKLIKYVFDNRETEDITFSTLVERVIQQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 LEGAFALVFKSVHFPGQAVGTRRGSPLLIGVRSEHKLSTDHIPILYRTARTQIGSKFTRW :::::::::::::.::.::.:::::::::::::..::::..::::::: . CCDS43 LEGAFALVFKSVHYPGEAVATRRGSPLLIGVRSKYKLSTEQIPILYRTCTLE-------- 180 190 200 210 220 250 260 270 280 290 pF1KE2 GSQGERGKDKKGSCN--LSRVDSTTCLFPVEEKAVEYYFASDASAVIEHTNRVIFLEDDD . :. :. ..:.::..:: : .::::..:::::::.:::::::::::::: CCDS43 --------NVKNICKTRMKRLDSSACLHAVGDKAVEFFFASDASAIIEHTNRVIFLEDDD 230 240 250 260 270 280 300 310 320 330 340 350 pF1KE2 VAAVVDGRLSIHRIKRTAGDHPGRAVQTLQMELQQIMKGNFSSFMQKEIFEQPESVVNTM .:::.::.:::::.::.:.: :.::.::::::::::::::::.::::::::::::: ::: CCDS43 IAAVADGKLSIHRVKRSASDDPSRAIQTLQMELQQIMKGNFSAFMQKEIFEQPESVFNTM 290 300 310 320 330 340 360 370 380 390 400 410 pF1KE2 RGRVNFDDYTVNLGGLKDHIKEIQRCRRLILIACGTSYHAGVATRQVLEELTELPVMVEL ::::::. :: :::::::.:::.::::::.:.:::::::.::::::::::::::::::: CCDS43 RGRVNFETNTVLLGGLKDHLKEIRRCRRLIVIGCGTSYHAAVATRQVLEELTELPVMVEL 350 360 370 380 390 400 420 430 440 450 460 470 pF1KE2 ASDFLDRNTPVFRDDVCFFLSQSGETADTLMGLRYCKERGALTVGITNTVGSSISRETDC :::::::::::::::::::.::::::::::..:::::.:::::::.:::::::::::::: CCDS43 ASDFLDRNTPVFRDDVCFFISQSGETADTLLALRYCKDRGALTVGVTNTVGSSISRETDC 410 420 430 440 450 460 480 490 500 510 520 530 pF1KE2 GVHINAGPEIGVASTKAYTSQFVSLVMFALMMCDDRISMQERRKEIMLGLKRLPDLIKEV ::::::::::::::::::::::.:::::.::: .::::.:.::.::. ::. ::.::::: CCDS43 GVHINAGPEIGVASTKAYTSQFISLVMFGLMMSEDRISLQNRRQEIIRGLRSLPELIKEV 470 480 490 500 510 520 540 550 560 570 580 590 pF1KE2 LSMDDEIQKLATELYHQKSVLIMGRGYHYATCLEGALKIKEITYMHSEGILAGELKHGPL ::....:. :: ::: :.:.:.:::::.:::::::::::::::::::::::::::::::: CCDS43 LSLEEKIHDLALELYTQRSLLVMGRGYNYATCLEGALKIKEITYMHSEGILAGELKHGPL 530 540 550 560 570 580 600 610 620 630 640 650 pF1KE2 ALVDKLMPVIMIIMRDHTYAKCQNALQQVVARQGRPVVICDKEDTETIKNTKRTIKVPHS ::.:: :::::.::.: .::::::::::.::::::...:.:.:::. : . .::..::. CCDS43 ALIDKQMPVIMVIMKDPCFAKCQNALQQVTARQGRPIILCSKDDTESSKFAYKTIELPHT 590 600 610 620 630 640 660 670 680 690 pF1KE2 VDCLQGILSVIPLQLLAFHLAVLRGYDVDFPRNLAKSVTVE ::::::::::::::::.:::::::::::::::::::::::: CCDS43 VDCLQGILSVIPLQLLSFHLAVLRGYDVDFPRNLAKSVTVE 650 660 670 680 699 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Jul 3 20:33:25 2020 done: Fri Jul 3 20:33:26 2020 Total Scan time: 1.530 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]