FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2422, 216 aa 1>>>pF1KE2422 216 - 216 aa - 216 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4678+/-0.000791; mu= 12.1854+/- 0.047 mean_var=55.5289+/-11.222, 0's: 0 Z-trim(105.7): 21 B-trim: 504 in 1/49 Lambda= 0.172113 statistics sampled from 8535 (8552) to 8535 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.263), width: 16 Scan time: 1.470 The best scores are: opt bits E(32554) CCDS34002.1 MOB1B gene_id:92597|Hs108|chr4 ( 216) 1465 371.7 1.9e-103 CCDS58903.1 MOB1B gene_id:92597|Hs108|chr4 ( 221) 1432 363.5 5.7e-101 CCDS46340.1 MOB1A gene_id:55233|Hs108|chr2 ( 216) 1412 358.6 1.8e-99 CCDS12081.1 MOB3A gene_id:126308|Hs108|chr19 ( 217) 857 220.7 5.4e-58 CCDS6520.1 MOB3B gene_id:79817|Hs108|chr9 ( 216) 838 216.0 1.4e-56 CCDS540.1 MOB3C gene_id:148932|Hs108|chr1 ( 216) 810 209.1 1.8e-54 CCDS539.1 MOB3C gene_id:148932|Hs108|chr1 ( 268) 810 209.1 2.1e-54 CCDS53591.1 MOB2 gene_id:81532|Hs108|chr11 ( 268) 551 144.8 4.9e-35 >>CCDS34002.1 MOB1B gene_id:92597|Hs108|chr4 (216 aa) initn: 1465 init1: 1465 opt: 1465 Z-score: 1970.6 bits: 371.7 E(32554): 1.9e-103 Smith-Waterman score: 1465; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216) 10 20 30 40 50 60 pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN 130 140 150 160 170 180 190 200 210 pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR :::::::::::::::::::::::::::::::::::: CCDS34 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR 190 200 210 >>CCDS58903.1 MOB1B gene_id:92597|Hs108|chr4 (221 aa) initn: 1432 init1: 1432 opt: 1432 Z-score: 1926.2 bits: 363.5 E(32554): 5.7e-101 Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:11-221) 10 20 30 40 50 pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE2 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE 130 140 150 160 170 180 180 190 200 210 pF1KE2 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR ::::::::::::::::::::::::::::::::::::::::: CCDS58 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR 190 200 210 220 >>CCDS46340.1 MOB1A gene_id:55233|Hs108|chr2 (216 aa) initn: 1412 init1: 1412 opt: 1412 Z-score: 1899.5 bits: 358.6 E(32554): 1.8e-99 Smith-Waterman score: 1412; 95.8% identity (98.6% similar) in 216 aa overlap (1-216:1-216) 10 20 30 40 50 60 pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN :::::.::::::::::::::::::::::::::::::::::::.:::::::::::::.::: CCDS46 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT ::::::::::::::::.:::: :::::::::.:::::::::::::::::::::::::::: CCDS46 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN :::::::::::::::::::::::::::::::::::::::::::::::: :.::::::::: CCDS46 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN 130 140 150 160 170 180 190 200 210 pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR ::::::::::::::::::::::::::::::: :::: CCDS46 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR 190 200 210 >>CCDS12081.1 MOB3A gene_id:126308|Hs108|chr19 (217 aa) initn: 874 init1: 770 opt: 857 Z-score: 1154.7 bits: 220.7 E(32554): 5.4e-58 Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (11-211:14-215) 10 20 30 40 50 pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEW :::.::... :....:: :.:.:.:..: .::.::.:: :::::.: CCDS12 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 VAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYID :::..:::::..:..::::.: :::.::::::.::::::.: : ...:: :::.:.: CCDS12 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE2 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEE :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. : CCDS12 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE 130 140 150 160 170 180 180 190 200 210 pF1KE2 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR ::.:: .::: .::.::.::: .:: ::.:. .. CCDS12 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 190 200 210 >>CCDS6520.1 MOB3B gene_id:79817|Hs108|chr9 (216 aa) initn: 848 init1: 740 opt: 838 Z-score: 1129.2 bits: 216.0 E(32554): 1.4e-56 Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (11-211:13-214) 10 20 30 40 50 pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWV :::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.:: CCDS65 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 AVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDY ::..:::::.::..:::: .::::..:::::.::::::.: : . ::: ::.:.. CCDS65 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE2 LMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEA :: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :: . :: CCDS65 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA 130 140 150 160 170 180 180 190 200 210 pF1KE2 HLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR :.:: .::: .:: :.:::::.:: ::.:. .. CCDS65 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 190 200 210 >>CCDS540.1 MOB3C gene_id:148932|Hs108|chr1 (216 aa) initn: 806 init1: 720 opt: 810 Z-score: 1091.6 bits: 209.1 E(32554): 1.8e-54 Smith-Waterman score: 810; 50.5% identity (82.7% similar) in 202 aa overlap (11-211:13-214) 10 20 30 40 50 pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWV :::.:.: . :....:: :.:.:.: :: .:: .: :: ::....:. CCDS54 MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 AVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDY ::..:::::.::..:::... :.: :::::..::.:::.: : . ..: : :::.:. CCDS54 AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE2 LMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEA :: :.. ..:: .::...::::::::..: :: :::::..:.: .::: .... :: CCDS54 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 130 140 150 160 170 180 180 190 200 210 pF1KE2 HLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR :.:: .::: .:..::.:.:.::: ::.:. :.. CCDS54 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 190 200 210 >>CCDS539.1 MOB3C gene_id:148932|Hs108|chr1 (268 aa) initn: 806 init1: 720 opt: 810 Z-score: 1090.0 bits: 209.1 E(32554): 2.1e-54 Smith-Waterman score: 810; 50.5% identity (82.7% similar) in 202 aa overlap (11-211:65-266) 10 20 30 pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG- :::.:.: . :....:: :.:.:.: :: CCDS53 IWYPQVRAPGQQPQAQLAMALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGL 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE2 NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWAD .:: .: :: ::....:.::..:::::.::..:::... :.: :::::..::.:::.: : CCDS53 DLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQD 100 110 120 130 140 150 100 110 120 130 140 150 pF1KE2 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY . ..: : :::.:. :: :.. ..:: .::...::::::::..: :: :::::. CCDS53 ERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVF 160 170 180 190 200 210 160 170 180 190 200 210 pF1KE2 AHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR .:.: .::: .... :::.:: .::: .:..::.:.:.::: ::.:. :.. CCDS53 VHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 220 230 240 250 260 >>CCDS53591.1 MOB2 gene_id:81532|Hs108|chr11 (268 aa) initn: 497 init1: 343 opt: 551 Z-score: 742.5 bits: 144.8 E(32554): 4.9e-35 Smith-Waterman score: 551; 42.3% identity (71.6% similar) in 208 aa overlap (8-213:37-240) 10 20 30 pF1KE2 MSFLFGSRSSKTFKP--KKNIPEGSHQYELLKHAEAT :.::. :: :: : . : .:..: CCDS53 SLPEDQARPGQSLQSGLCCKMVLQAVSKVLRKSKA-KPNGKKPAAEERKAYLEPEHTKAR 10 20 30 40 50 60 40 50 60 70 80 90 pF1KE2 LGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEY . . ... :.::. :::::.: ::. ::..::. :.::..::: :.: .:.. . .: CCDS53 ITDFQFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVC-NTQY 70 80 90 100 110 120 100 110 120 130 140 150 pF1KE2 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL .: : . : .::.::.:.:..:. :: . :: .::.: : ::..: :... : ..: CCDS53 YWYDERG--KKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHL 130 140 150 160 170 180 160 170 180 190 200 210 pF1KE2 FRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKD :.: :::: :: .. :. ..:::: . :::.:..::::.: .: : ...: : : : CCDS53 FHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLCSGA 190 200 210 220 230 240 pF1KE2 R CCDS53 GGVHSGGSGDGAGSGGPGAQNHVKER 250 260 216 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 19:39:27 2016 done: Mon Nov 7 19:39:27 2016 Total Scan time: 1.470 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]