FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2422, 216 aa
1>>>pF1KE2422 216 - 216 aa - 216 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4678+/-0.000791; mu= 12.1854+/- 0.047
mean_var=55.5289+/-11.222, 0's: 0 Z-trim(105.7): 21 B-trim: 504 in 1/49
Lambda= 0.172113
statistics sampled from 8535 (8552) to 8535 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.263), width: 16
Scan time: 1.470
The best scores are: opt bits E(32554)
CCDS34002.1 MOB1B gene_id:92597|Hs108|chr4 ( 216) 1465 371.7 1.9e-103
CCDS58903.1 MOB1B gene_id:92597|Hs108|chr4 ( 221) 1432 363.5 5.7e-101
CCDS46340.1 MOB1A gene_id:55233|Hs108|chr2 ( 216) 1412 358.6 1.8e-99
CCDS12081.1 MOB3A gene_id:126308|Hs108|chr19 ( 217) 857 220.7 5.4e-58
CCDS6520.1 MOB3B gene_id:79817|Hs108|chr9 ( 216) 838 216.0 1.4e-56
CCDS540.1 MOB3C gene_id:148932|Hs108|chr1 ( 216) 810 209.1 1.8e-54
CCDS539.1 MOB3C gene_id:148932|Hs108|chr1 ( 268) 810 209.1 2.1e-54
CCDS53591.1 MOB2 gene_id:81532|Hs108|chr11 ( 268) 551 144.8 4.9e-35
>>CCDS34002.1 MOB1B gene_id:92597|Hs108|chr4 (216 aa)
initn: 1465 init1: 1465 opt: 1465 Z-score: 1970.6 bits: 371.7 E(32554): 1.9e-103
Smith-Waterman score: 1465; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
130 140 150 160 170 180
190 200 210
pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
::::::::::::::::::::::::::::::::::::
CCDS34 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
190 200 210
>>CCDS58903.1 MOB1B gene_id:92597|Hs108|chr4 (221 aa)
initn: 1432 init1: 1432 opt: 1432 Z-score: 1926.2 bits: 363.5 E(32554): 5.7e-101
Smith-Waterman score: 1432; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:11-221)
10 20 30 40 50
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
130 140 150 160 170 180
180 190 200 210
pF1KE2 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
:::::::::::::::::::::::::::::::::::::::::
CCDS58 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
190 200 210 220
>>CCDS46340.1 MOB1A gene_id:55233|Hs108|chr2 (216 aa)
initn: 1412 init1: 1412 opt: 1412 Z-score: 1899.5 bits: 358.6 E(32554): 1.8e-99
Smith-Waterman score: 1412; 95.8% identity (98.6% similar) in 216 aa overlap (1-216:1-216)
10 20 30 40 50 60
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
:::::.::::::::::::::::::::::::::::::::::::.:::::::::::::.:::
CCDS46 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
::::::::::::::::.:::: :::::::::.::::::::::::::::::::::::::::
CCDS46 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
:::::::::::::::::::::::::::::::::::::::::::::::: :.:::::::::
CCDS46 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
130 140 150 160 170 180
190 200 210
pF1KE2 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
::::::::::::::::::::::::::::::: ::::
CCDS46 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
190 200 210
>>CCDS12081.1 MOB3A gene_id:126308|Hs108|chr19 (217 aa)
initn: 874 init1: 770 opt: 857 Z-score: 1154.7 bits: 220.7 E(32554): 5.4e-58
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (11-211:14-215)
10 20 30 40 50
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEW
:::.::... :....:: :.:.:.:..: .::.::.:: :::::.:
CCDS12 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 VAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYID
:::..:::::..:..::::.: :::.::::::.::::::.: : ...:: :::.:.:
CCDS12 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEE
:: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. :
CCDS12 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
130 140 150 160 170 180
180 190 200 210
pF1KE2 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
::.:: .::: .::.::.::: .:: ::.:. ..
CCDS12 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
190 200 210
>>CCDS6520.1 MOB3B gene_id:79817|Hs108|chr9 (216 aa)
initn: 848 init1: 740 opt: 838 Z-score: 1129.2 bits: 216.0 E(32554): 1.4e-56
Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (11-211:13-214)
10 20 30 40 50
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWV
:::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.::
CCDS65 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 AVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDY
::..:::::.::..:::: .::::..:::::.::::::.: : . ::: ::.:..
CCDS65 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 LMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEA
:: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :: . ::
CCDS65 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA
130 140 150 160 170 180
180 190 200 210
pF1KE2 HLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
:.:: .::: .:: :.:::::.:: ::.:. ..
CCDS65 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
190 200 210
>>CCDS540.1 MOB3C gene_id:148932|Hs108|chr1 (216 aa)
initn: 806 init1: 720 opt: 810 Z-score: 1091.6 bits: 209.1 E(32554): 1.8e-54
Smith-Waterman score: 810; 50.5% identity (82.7% similar) in 202 aa overlap (11-211:13-214)
10 20 30 40 50
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWV
:::.:.: . :....:: :.:.:.: :: .:: .: :: ::....:.
CCDS54 MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 AVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDY
::..:::::.::..:::... :.: :::::..::.:::.: : . ..: : :::.:.
CCDS54 AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 LMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEA
:: :.. ..:: .::...::::::::..: :: :::::..:.: .::: .... ::
CCDS54 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA
130 140 150 160 170 180
180 190 200 210
pF1KE2 HLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
:.:: .::: .:..::.:.:.::: ::.:. :..
CCDS54 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH
190 200 210
>>CCDS539.1 MOB3C gene_id:148932|Hs108|chr1 (268 aa)
initn: 806 init1: 720 opt: 810 Z-score: 1090.0 bits: 209.1 E(32554): 2.1e-54
Smith-Waterman score: 810; 50.5% identity (82.7% similar) in 202 aa overlap (11-211:65-266)
10 20 30
pF1KE2 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
:::.:.: . :....:: :.:.:.: ::
CCDS53 IWYPQVRAPGQQPQAQLAMALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE2 NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWAD
.:: .: :: ::....:.::..:::::.::..:::... :.: :::::..::.:::.: :
CCDS53 DLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQD
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE2 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
. ..: : :::.:. :: :.. ..:: .::...::::::::..: :: :::::.
CCDS53 ERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVF
160 170 180 190 200 210
160 170 180 190 200 210
pF1KE2 AHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
.:.: .::: .... :::.:: .::: .:..::.:.:.::: ::.:. :..
CCDS53 VHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH
220 230 240 250 260
>>CCDS53591.1 MOB2 gene_id:81532|Hs108|chr11 (268 aa)
initn: 497 init1: 343 opt: 551 Z-score: 742.5 bits: 144.8 E(32554): 4.9e-35
Smith-Waterman score: 551; 42.3% identity (71.6% similar) in 208 aa overlap (8-213:37-240)
10 20 30
pF1KE2 MSFLFGSRSSKTFKP--KKNIPEGSHQYELLKHAEAT
:.::. :: :: : . : .:..:
CCDS53 SLPEDQARPGQSLQSGLCCKMVLQAVSKVLRKSKA-KPNGKKPAAEERKAYLEPEHTKAR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE2 LGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEY
. . ... :.::. :::::.: ::. ::..::. :.::..::: :.: .:.. . .:
CCDS53 ITDFQFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVC-NTQY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE2 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL
.: : . : .::.::.:.:..:. :: . :: .::.: : ::..: :... : ..:
CCDS53 YWYDERG--KKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE2 FRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKD
:.: :::: :: .. :. ..:::: . :::.:..::::.: .: : ...: : : :
CCDS53 FHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLCSGA
190 200 210 220 230 240
pF1KE2 R
CCDS53 GGVHSGGSGDGAGSGGPGAQNHVKER
250 260
216 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:39:27 2016 done: Mon Nov 7 19:39:27 2016
Total Scan time: 1.470 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]