FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2428, 349 aa 1>>>pF1KE2428 349 - 349 aa - 349 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1210+/-0.000389; mu= 16.7374+/- 0.024 mean_var=59.4871+/-12.049, 0's: 0 Z-trim(111.8): 21 B-trim: 0 in 0/50 Lambda= 0.166289 statistics sampled from 20526 (20542) to 20526 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.612), E-opt: 0.2 (0.241), width: 16 Scan time: 6.380 The best scores are: opt bits E(85289) NP_005267 (OMIM: 138420,614480) glycerol-3-phospha ( 349) 2322 565.6 5.6e-161 NP_055956 (OMIM: 611777,611778) glycerol-3-phospha ( 351) 1733 424.3 1.9e-118 NP_001244128 (OMIM: 138420,614480) glycerol-3-phos ( 326) 1688 413.5 3.2e-115 XP_006713131 (OMIM: 611777,611778) PREDICTED: glyc ( 304) 1199 296.2 6.2e-80 >>NP_005267 (OMIM: 138420,614480) glycerol-3-phosphate d (349 aa) initn: 2322 init1: 2322 opt: 2322 Z-score: 3011.1 bits: 565.6 E(85289): 5.6e-161 Smith-Waterman score: 2322; 100.0% identity (100.0% similar) in 349 aa overlap (1-349:1-349) 10 20 30 40 50 60 pF1KE2 MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHEN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 VKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 GVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 MQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGP 250 260 270 280 290 300 310 320 330 340 pF1KE2 ETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM ::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM 310 320 330 340 >>NP_055956 (OMIM: 611777,611778) glycerol-3-phosphate d (351 aa) initn: 1733 init1: 1733 opt: 1733 Z-score: 2247.4 bits: 424.3 E(85289): 1.9e-118 Smith-Waterman score: 1733; 71.8% identity (90.5% similar) in 347 aa overlap (2-348:4-350) 10 20 30 40 50 pF1KE2 MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQH : :::::::::::::.:::.:.:. .: .: : :::::: ..:.:::.:::..: NP_055 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 ENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISL :::::::::::: ::::. .. .:..:::.:.::.::::: .:::.. :.. .: ::.: NP_055 ENVKYLPGHKLPENVVAMSNLSEAVQDADLLVFVIPHQFIHRICDEITGRVPKKALGITL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE2 IKGVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLK :::.::::.::::::..: :..:: .:::::::::.::: ::::::::: : .: :.: NP_055 IKGIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE2 ELMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAF ::.::::::::::...::::.::::::.::::::::::: ::::::::::::::::::: NP_055 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE2 AKLFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQ :..::.: ::.::::::::::::::::::::::.::::::::::.::.::::.::::::: NP_055 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ 250 260 270 280 290 300 300 310 320 330 340 pF1KE2 GPETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM ::.:. :.: ::..:::.:::::: :::..:::..:: :.. :::.:::: NP_055 GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHT 310 320 330 340 350 >>NP_001244128 (OMIM: 138420,614480) glycerol-3-phosphat (326 aa) initn: 1688 init1: 1688 opt: 1688 Z-score: 2189.5 bits: 413.5 E(85289): 3.2e-115 Smith-Waterman score: 2119; 93.4% identity (93.4% similar) in 349 aa overlap (1-349:1-326) 10 20 30 40 50 60 pF1KE2 MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHEN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 VKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIK ::::::::::::: :::::::::::::::::::::::: NP_001 VKYLPGHKLPPNV-----------------------FIGKICDQLKGHLKANATGISLIK 70 80 90 130 140 150 160 170 180 pF1KE2 GVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKEL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE2 MQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KE2 LFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGP 220 230 240 250 260 270 310 320 330 340 pF1KE2 ETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM 280 290 300 310 320 >>XP_006713131 (OMIM: 611777,611778) PREDICTED: glycerol (304 aa) initn: 1538 init1: 1199 opt: 1199 Z-score: 1556.0 bits: 296.2 E(85289): 6.2e-80 Smith-Waterman score: 1448; 64.8% identity (79.0% similar) in 347 aa overlap (2-348:4-303) 10 20 30 40 50 pF1KE2 MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQH : :::::::::::::.:::.:.:. .: .: : :::::: ..:.:::.:::..: XP_006 MAAAPLKVCIVGSGNWGSAVAKIIGNNVKKLQKFASTVKMWVFEETVNGRKLTDIINNDH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 ENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISL :::::::::::: :: XP_006 ENVKYLPGHKLPENV--------------------------------------------- 70 120 130 140 150 160 170 pF1KE2 IKGVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLK :.::::.::::::..: :..:: .:::::::::.::: ::::::::: : .: :.: XP_006 --GIDEGPEGLKLISDIIREKMGIDISVLMGANIANEVAAEKFCETTIGSKVMENGLLFK 80 90 100 110 120 130 180 190 200 210 220 230 pF1KE2 ELMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAF ::.::::::::::...::::.::::::.::::::::::: ::::::::::::::::::: XP_006 ELLQTPNFRITVVDDADTVELCGALKNIVAVGAGFCDGLRCGDNTKAAVIRLGLMEMIAF 140 150 160 170 180 190 240 250 260 270 280 290 pF1KE2 AKLFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQ :..::.: ::.::::::::::::::::::::::.::::::::::.::.::::.::::::: XP_006 ARIFCKGQVSTATFLESCGVADLITTCYGGRNRRVAEAFARTGKTIEELEKEMLNGQKLQ 200 210 220 230 240 250 300 310 320 330 340 pF1KE2 GPETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM ::.:. :.: ::..:::.:::::: :::..:::..:: :.. :::.:::: XP_006 GPQTSAEVYRILKQKGLLDKFPLFTAVYQICYESRPVQEMLSCLQSHPEHT 260 270 280 290 300 349 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 19:51:21 2016 done: Mon Nov 7 19:51:22 2016 Total Scan time: 6.380 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]