FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2435, 333 aa 1>>>pF1KE2435 333 - 333 aa - 333 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7679+/-0.000477; mu= 19.1259+/- 0.029 mean_var=71.1031+/-14.674, 0's: 0 Z-trim(108.0): 44 B-trim: 54 in 1/54 Lambda= 0.152100 statistics sampled from 15982 (16023) to 15982 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.529), E-opt: 0.2 (0.188), width: 16 Scan time: 6.480 The best scores are: opt bits E(85289) NP_789787 (OMIM: 171200,607751) taste receptor typ ( 333) 2223 497.5 1.6e-140 NP_076408 (OMIM: 604793) taste receptor type 2 mem ( 318) 511 121.8 1.9e-27 NP_058639 (OMIM: 604868) taste receptor type 2 mem ( 316) 491 117.5 3.9e-26 NP_076406 (OMIM: 604795) taste receptor type 2 mem ( 312) 457 110.0 6.9e-24 NP_852094 (OMIM: 613966) taste receptor type 2 mem ( 314) 440 106.3 9.2e-23 NP_076409 (OMIM: 604792) taste receptor type 2 mem ( 303) 437 105.6 1.4e-22 NP_076407 (OMIM: 604794) taste receptor type 2 mem ( 309) 423 102.5 1.2e-21 NP_076411 (OMIM: 604790) taste receptor type 2 mem ( 317) 410 99.7 8.9e-21 NP_795364 (OMIM: 613965) taste receptor type 2 mem ( 307) 392 95.7 1.3e-19 NP_795363 (OMIM: 613964) taste receptor type 2 mem ( 323) 381 93.3 7.4e-19 NP_058640 (OMIM: 604869) taste receptor type 2 mem ( 299) 356 87.8 3.1e-17 NP_795370 (OMIM: 613962) taste receptor type 2 mem ( 309) 338 83.9 5e-16 NP_795365 (OMIM: 612668) taste receptor type 2 mem ( 309) 320 79.9 7.7e-15 NP_795369 (OMIM: 613961) taste receptor type 2 mem ( 299) 319 79.7 8.7e-15 NP_795368 (OMIM: 612774) taste receptor type 2 mem ( 309) 317 79.3 1.2e-14 NP_001091112 (OMIM: 613963) taste receptor type 2 ( 319) 315 78.8 1.7e-14 NP_803186 (OMIM: 613968) taste receptor type 2 mem ( 318) 311 78.0 3.1e-14 NP_795367 (OMIM: 613967) taste receptor type 2 mem ( 299) 306 76.8 6.3e-14 XP_006726600 (OMIM: 612668) PREDICTED: taste recep ( 299) 306 76.8 6.3e-14 XP_003961040 (OMIM: 612668) PREDICTED: taste recep ( 299) 306 76.8 6.3e-14 NP_795366 (OMIM: 612669) taste receptor type 2 mem ( 309) 302 76.0 1.2e-13 NP_062545 (OMIM: 604796) taste receptor type 2 mem ( 299) 282 71.6 2.4e-12 NP_795371 (OMIM: 609627) taste receptor type 2 mem ( 299) 264 67.6 3.7e-11 NP_058641 (OMIM: 103780,604867) taste receptor typ ( 291) 245 63.4 6.6e-10 NP_076410 (OMIM: 604791) taste receptor type 2 mem ( 307) 232 60.6 5e-09 NP_061853 (OMIM: 605062) taste receptor type 2 mem ( 299) 230 60.2 6.6e-09 >>NP_789787 (OMIM: 171200,607751) taste receptor type 2 (333 aa) initn: 2223 init1: 2223 opt: 2223 Z-score: 2643.8 bits: 497.5 E(85289): 1.6e-140 Smith-Waterman score: 2223; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 RLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 RLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 AHIKALKSLVSFFCFFVISSCVAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_789 AHIKALKSLVSFFCFFVISSCVAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISG 250 260 270 280 290 300 310 320 330 pF1KE2 NAKLRRAVMTILLWAQSSLKVRADHKADSRTLC ::::::::::::::::::::::::::::::::: NP_789 NAKLRRAVMTILLWAQSSLKVRADHKADSRTLC 310 320 330 >>NP_076408 (OMIM: 604793) taste receptor type 2 member (318 aa) initn: 547 init1: 257 opt: 511 Z-score: 613.8 bits: 121.8 E(85289): 1.9e-27 Smith-Waterman score: 511; 32.5% identity (62.8% similar) in 323 aa overlap (13-326:4-316) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL .:..:.::..: ::.::.: :::. ::: : ::.. ... : .: : NP_076 MADKVQTTLLFLAVGEFSVGILGNAFIGLVNCMDWVKKRKIASIDLILTSL 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK .:::. : ...:. . :. . . .. .. : ..: ..:. ..:.:.:::. : : NP_076 AISRICLLCVILLDCFILVLYPDVYAT-GKEMRIIDFFWTLTNHLSIWFATCLSIYYFFK 60 70 80 90 100 110 130 140 150 160 170 pF1KE2 LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLF----- . : : ... . ..: :: .::: :.:: : :.: : .. : NP_076 IGNFFHPLFLWMKWRIDRVISWILLG-------CVVLSV--FISLPATENLNADFRFCVK 120 130 140 150 160 180 190 200 210 220 230 pF1KE2 MNNNTRLNW--QIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRN . .: :.: ... . . :: : .. :: . :.: .: .:: ::.: :.. . . NP_076 AKRKTNLTWSCRVNKTQHASTKLFLNLATLLPFCVCLMSFFLLILSLRRHIRRMQLSATG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE2 SRDPSLEAHIKALKSLVSFFCFFVISSCVAFISVPLLILWRDKIGVMVCVGIMAACPSGH :::: :::..:::...::. .:. .:.. .. . ...:. .: ::.: NP_076 CRDPSTEAHVRALKAVISFLLLFIAYYLSFLIATSSYFMPETELAVIFGESIALIYPSSH 230 240 250 260 270 280 300 310 320 330 pF1KE2 AAILISGNAKLRRAVMTILLWAQSSLKVRA--DHKADSRTLC . ::: :: :::.: . .. ..: :: : .:: NP_076 SFILILGNNKLRHASLKVIWKVMSILKGRKFQQHKQI 290 300 310 >>NP_058639 (OMIM: 604868) taste receptor type 2 member (316 aa) initn: 493 init1: 248 opt: 491 Z-score: 590.1 bits: 117.5 E(85289): 3.9e-26 Smith-Waterman score: 491; 31.4% identity (62.4% similar) in 303 aa overlap (18-320:9-307) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL ::..: .:..:.:.: :. ::: . : . .: :: .. : NP_058 MMGLTEGVFLILSGTQFTLGILVNCFIELVNGSSWFKTKRMSLSDFIITTL 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK .. :..: ... ... : .:. .. . .: : . : ..:. ..:::.::..::: : NP_058 ALLRIILLCIILTDSF-LIEFSPNTHDSGIIMQIIDVSWTFTNHLSIWLATCLGVLYCLK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNT . ::: .. : ::: . :::: .: :: :. . : ..: . . :. NP_058 IASFSHPTFLWLKWRVSRVMVWMLLGALLLSCGSTASLINEF---KLYSVFRGIEATRNV 120 130 140 150 160 190 200 210 220 230 240 pF1KE2 RLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLE ... : . . .. :: .::... :.: ..: ::::: : : .::::. : NP_058 TEHFRKKRSEYYLIHVLGTLWYLPPLIVSLASYSLLIFSLGRHTRQMLQNGTSSRDPTTE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE2 AHIKALKSLVSFFCFFVISSCVAFISVPLLILWRDKIGVMVCVGIMAACPSGHAAILISG :: .:.. ..::: .:.. . .:. .: . :.. :. . :.::. ::: : NP_058 AHKRAIRIILSFFFLFLLYFLAFLIASFGNFLPKTKMAKMIGEVMTMFYPAGHSFILILG 230 240 250 260 270 280 310 320 330 pF1KE2 NAKLRRAVMTILLWAQSSLKVRADHKADSRTLC :.::... ...: .. :: NP_058 NSKLKQTFVVMLRCESGHLKPGSKGPIFS 290 300 310 >>NP_076406 (OMIM: 604795) taste receptor type 2 member (312 aa) initn: 425 init1: 239 opt: 457 Z-score: 549.8 bits: 110.0 E(85289): 6.9e-24 Smith-Waterman score: 457; 28.7% identity (64.7% similar) in 317 aa overlap (14-322:5-307) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL ... .... . :...:. :.:. ::: : .::. .: : .:. : NP_076 MPSAIEAIYIILIAGELTIGIWGNGFIVLVNCIDWLKRRDISLIDIILISL 10 20 30 40 50 70 80 90 100 110 pF1KE2 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAII----MLWMIANQANLWLAACLSLL .:::. : : .:.: : : : ... .... ..: .::...::...:::.. NP_076 AISRICL-----LCVISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIF 60 70 80 90 100 120 130 140 150 160 170 pF1KE2 YCSKLIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFT-VTTVLF : :. .:: :.. :.. ::....:.:.: : . ... .: :. . :: NP_076 YLLKIANISHPFFF----WLKLKINKVMLAILLGSFLISLI-----ISVPKNDDMWYHLF 110 120 130 140 150 180 190 200 210 220 230 pF1KE2 -MNNNTRLNWQIKDLNLFYSF--LFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTR .... ..:..: .. .: : : . ::.: :.: .: :: :: . ..... NP_076 KVSHEENITWKFKVSKIPGTFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHAT 160 170 180 190 200 210 240 250 260 270 280 290 pF1KE2 NSRDPSLEAHIKALKSLVSFFCFFVISSCVAFISVPLLILWRDKIGVMVCVGIMAACPSG . :::: :::..:.:... :. .... : .. . .. . :. .:. . . ::. NP_076 GFRDPSTEAHMRAIKAVIIFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSS 220 230 240 250 260 270 300 310 320 330 pF1KE2 HAAILISGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC :. ::: ::.:::.: . .: ... :. : NP_076 HSFILIMGNSKLREAFLKMLRFVKCFLRRRKPFVP 280 290 300 310 >>NP_852094 (OMIM: 613966) taste receptor type 2 member (314 aa) initn: 433 init1: 207 opt: 440 Z-score: 529.7 bits: 106.3 E(85289): 9.2e-23 Smith-Waterman score: 440; 29.8% identity (63.1% similar) in 312 aa overlap (13-314:4-300) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL :. . ::.... :: ...: :.:. ::: . .: : . ..: .: :: NP_852 MATELDKIFLILAIAEFIISMLGNVFIGLVNCSEGIKNQKVFSADFILTCL 10 20 30 40 50 70 80 90 100 110 pF1KE2 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSY---QAIIMLWMIANQANLWLAACLSLLY .:: . : :.. .. . . :. : .: ...:::: ..:. . :::.:::..: NP_852 AISTI---GQLLVILFD-SFLVGLASHLYTTYRLGKTVIMLWHMTNHLTTWLATCLSIFY 60 70 80 90 100 120 130 140 150 160 170 pF1KE2 CSKLIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVL--CVWCFFSRPHFTV----T :. .: :.... :. ... :.. ... : . .. : .: ... . NP_852 FFKIAHFPHSLFL----WLRWRMNGMIVMLLILSLFLLIFDSLVLEIFIDISLNIIDKSN 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE2 TVLFMNNNTRLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYT .:..... : ... :. . : : : :: :::.: .: .:: :: :..:. . NP_852 LTLYLDESKTLYDKLSILKTLLS-----LTSFIPFSLFLTSLLFLFLSLVRHTRNLKLSS 170 180 190 200 210 240 250 260 270 280 290 pF1KE2 RNSRDPSLEAHIKALKSLVSFFCFFVISS-CVAFISVPLLILWRDKIGVMVCVGIMAACP .::: : ::: .:.: ..::. .:.. . . ...:: .: .: .. . : : NP_852 LGSRDSSTEAHRRAMKMVMSFLFLFIVHFFSLQVANWIFFMLWNNKCIKFVMLA-LNAFP 220 230 240 250 260 270 300 310 320 330 pF1KE2 SGHAAILISGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC : :. ::: ::.::..... ::: NP_852 SCHSFILILGNSKLQQTAVR-LLWHLRNYTKTPNPLPL 280 290 300 310 >>NP_076409 (OMIM: 604792) taste receptor type 2 member (303 aa) initn: 303 init1: 140 opt: 437 Z-score: 526.3 bits: 105.6 E(85289): 1.4e-22 Smith-Waterman score: 437; 29.2% identity (61.4% similar) in 308 aa overlap (16-316:7-302) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL : : .. . :: .: :.:.:. :.: : :... ::. : .:. : NP_076 MESALPSIFTLVIIAEFIIGNLSNGFIVLINCIDWVSKRELSSVDKLLIIL 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK .:::. : ...: . :. . . . . .:. :...:. :::::. .:..: : NP_076 AISRIGLIWEILVSWFLALHYLAIFVS-GTGLRIMIFSWIVSNHFNLWLATIFSIFYLLK 60 70 80 90 100 110 130 140 150 160 170 pF1KE2 LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNN-- . :: .. : :.. : ..::: . :. :.. .... ... NP_076 IASFSSPAFLYLKWRVNKVILMILLGTL----------VFLFLNLIQINMHIKDWLDRYE 120 130 140 150 160 180 190 200 210 220 230 pF1KE2 -NTRLNWQIKDLNLF-YSFLFCY-LWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSR :: :....:.. : : : . ..:. :: . ..: .: :: .:.. :.. .. : NP_076 RNTTWNFSMSDFETFSVSVKFTMTMFSLTPFTVAFISFLLLIFSLQKHLQKMQLNYKGHR 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE2 DPSLEAHIKALKSLVSFFCFFVISSCVAFISVPLLILWRDKIGVMVCVGIMAACPSGHAA :: ..: .::: ..::. :.. ..:: . :... . :.: : . ::.:. NP_076 DPRTKVHTNALKIVISFLLFYASFFLCVLISW-ISELYQNTVIYMLCETIGVFSPSSHSF 230 240 250 260 270 300 310 320 330 pF1KE2 ILISGNAKLRRAVMTIL--LWAQSSLKVRADHKADSRTLC .:: ::::::.: . . .::. NP_076 LLILGNAKLRQAFLLVAAKVWAKR 280 290 300 >>NP_076407 (OMIM: 604794) taste receptor type 2 member (309 aa) initn: 380 init1: 217 opt: 423 Z-score: 509.6 bits: 102.5 E(85289): 1.2e-21 Smith-Waterman score: 423; 27.3% identity (62.3% similar) in 297 aa overlap (18-312:9-300) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL :... . :: .:.: :... :::. : .:.. .:. : .: : NP_076 MFSPADNIFIILITGEFILGILGNGYIALVNWIDWIKKKKISTVDYILTNL 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK :.:. : ... ...: .. .. :.. .:. .: .:: :.:...::...: : NP_076 VIARICLISVMVVNGIVIV-LNPDVYTKNKQQIVIFTFWTFANYLNMWITTCLNVFYFLK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNT . :: ... : .. . .::: . : . ... . . .: . . . : NP_076 IASSSHPLFLWLKWKIDMVVHWILLGCFAISLLVSLIAAIVLSCDYRFHA--IAKHKRNI 120 130 140 150 160 190 200 210 220 230 240 pF1KE2 RLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPSLE .... . : . . :... ::.. :.: .:. :: :: . .:.:. .::::: : NP_076 TEMFHVSKIPYFEPLTLFNLFAIVPFIVSLISFFLLVRSLWRHTKQIKLYATGSRDPSTE 170 180 190 200 210 220 250 260 270 280 290 pF1KE2 AHIKALKSLVSFFCFFVISSCVAFISVPLLILWRDKIGVMVCVGIMAAC--PSGHAAILI .:..:.:...::. :: . ... . .. . :..: : .:: : ::. ::: NP_076 VHVRAIKTMTSFIFFFFLYYISSILMTFSYLMTKYKLAVEF--GEIAAILYPLGHSLILI 230 240 250 260 270 280 300 310 320 330 pF1KE2 SGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC : :::.. . .: NP_076 VLNNKLRQTFVRMLTCRKIACMI 290 300 >>NP_076411 (OMIM: 604790) taste receptor type 2 member (317 aa) initn: 372 init1: 151 opt: 410 Z-score: 494.0 bits: 99.7 E(85289): 8.9e-21 Smith-Waterman score: 410; 29.1% identity (59.8% similar) in 316 aa overlap (14-320:5-303) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL ..: : :. ..:: .: : :.:. ::: : :: . .:. : .: : NP_076 MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTAL 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 SISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYCSK .:::. : :.: : . : : .. .. . .: . :. ..:::. :. .: : NP_076 AISRISLVWLIFGSWCVSVFFPALFAT-EKMFRMLTNIWTVINHFSVWLATGLGTFYFLK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 LIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNNNT . ::..... : .: ......: ..: . . : . . :.... . :.: NP_076 IANFSNSIFLYL-KW---RVKKVVLVLLLVTSVFLFLNI--ALINIHINASINGYRRNKT 120 130 140 150 160 190 200 210 220 230 pF1KE2 ----RLNW-QIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSR :. ....: .. : .: .. :: : :. .: :. .: . :. .. : NP_076 CSSDSSNFTRFSSLIVLTSTVFIFI----PFTLSLAMFLLLIFSMWKHRKKMQHTVKISG 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE2 DPSLEAHIKALKSLVSFFCFFVISSCVAFISVPLLILW---RDKIGVMVCVGIMA-ACPS : : .:: ...::...:: ...: : :::: : : . .... .:. : :: NP_076 DASTKAH-RGVKSVITFFLLYAIFSLSFFISV-----WTSERLEENLIILSQVMGMAYPS 230 240 250 260 270 300 310 320 330 pF1KE2 GHAAILISGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC :. .:: :: :::.: ...::: . .: NP_076 CHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS 280 290 300 310 >>NP_795364 (OMIM: 613965) taste receptor type 2 member (307 aa) initn: 208 init1: 155 opt: 392 Z-score: 472.9 bits: 95.7 E(85289): 1.3e-19 Smith-Waterman score: 392; 28.4% identity (58.5% similar) in 306 aa overlap (19-316:11-302) 10 20 30 40 50 60 pF1KE2 MLTLTRIRTVSYEVRSTFLFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVLLCL :..:.: . .:. .:.:. :: . .. : : .:. : NP_795 MQAALTAFFVLLFSLLSL-LGIAANGFIVLVLGREWLRYGRLLPLDMILISL 10 20 30 40 50 70 80 90 100 110 pF1KE2 SISRLFLHGLLFLSAIQLTHF--QKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLYC . ::. :. ...... .. ::. . . : . . : . :.:..:. . ::.:.: NP_795 GASRFCLQ---LVGTVHNFYYSAQKVEYSGGLGRQFFHLHWHFLNSATFWFCSWLSVLFC 60 70 80 90 100 120 130 140 150 160 170 pF1KE2 SKLIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTVTTVLFMNN :. ..:. .. : . .::: .: : : :.: : . : . . ... NP_795 VKIANITHSTFLWLKWRFPGWVPWLLLGSVLISFIITLLFFW--VNYPVYQEFLIRKFSG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KE2 NTRLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNSRDPS : .:. . . .. : .::.: : .:::: .: :: :: . :. .. .::: NP_795 NMTYKWNTRIETYYFPSLKLVIWSIP-FSVFLVSIMLLINSLRRHTQRMQHNGHSLQDPS 170 180 190 200 210 220 240 250 260 270 280 290 pF1KE2 LEAHIKALKSLVSFFCFFVIS------SCVAFISVPLLILWRDKIGVMVCVGIMAACPSG .:: .:::::.::. ....: . . :::. . : .:.:..:... NP_795 TQAHTRALKSLISFLILYALSFLSLIIDAAKFISMQNDFYWPWQIAVYLCISV------- 230 240 250 260 270 300 310 320 330 pF1KE2 HAAILISGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC : ::: .: ::: . .:: :. NP_795 HPFILIFSNLKLRSVFSQLLLLARGFWVA 280 290 300 >>NP_795363 (OMIM: 613964) taste receptor type 2 member (323 aa) initn: 253 init1: 90 opt: 381 Z-score: 459.5 bits: 93.3 E(85289): 7.4e-19 Smith-Waterman score: 381; 27.6% identity (62.3% similar) in 297 aa overlap (15-307:17-306) 10 20 30 40 50 pF1KE2 MLTLTRIRTVSYEVRSTF-LFISVLEFAVGFLTNAFVFLVNFWDVVKRQALSNSDCVL . :: : .: .: .:.: ..:. . . .. ..: ..: .. NP_795 MATVNTDATDKDISKFKVTFTLVVSGIECITGILGSGFITAIYGAEWARGKTLPTGDRIM 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 LCLSISRLFLHGLLFLSAIQLTHFQKLSEPLNHSYQAIIMLWMIANQANLWLAACLSLLY : ::.:::.:. ..: : .. . .. : : . .. .. :..:::.:: :...: NP_795 LMLSFSRLLLQIWMMLENI-FSLLFRIVYNQNSVYILFKVITVFLNHSNLWFAAWLKVFY 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 CSKLIRFSHTFLICLASWVSRKISQMLLGIILCSCICTVLCVWCFFSRPHFTV---TTVL : .. :.: ... . .::: .:. .: . . : .:: :.: ... NP_795 CLRIANFNHPLFFLM----KRKII-VLMPWLLRLSVLVSLSFSFPLSRDVFNVYVNSSIP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 FMNNNTRLNWQIKDLNLFYSFLFCYLWSVPPFLLFLVSSGMLTVSLGRHMRTMKVYTRNS . ..:. . ... :. .: . :...:.... .: .:: :: : . .: NP_795 IPSSNSTEKKYFSETNMVNLVFFYNMGIFVPLIMFILAATLLILSLKRHTLHMGSNATGS 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 RDPSLEAHIKALKSLVSFFCFFVISSCVAFISVPLLILWRDKIGVMVCVGIMAACPSGHA ::::..::: :.:. :. ...... . :.:. .. .. ... : :::: :.::. NP_795 RDPSMKAHIGAIKATSYFLILYIFNAIALFLSTSNIFDTYSSWNIL-CKIIMAAYPAGHS 240 250 260 270 280 290 300 310 320 330 pF1KE2 AILISGNAKLRRAVMTILLWAQSSLKVRADHKADSRTLC . :: :: :::: NP_795 VQLILGNPGLRRAWKRFQHQVPLYLKGQTL 300 310 320 333 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 19:57:01 2016 done: Mon Nov 7 19:57:02 2016 Total Scan time: 6.480 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]