FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2454, 846 aa 1>>>pF1KE2454 846 - 846 aa - 846 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.3433+/-0.00108; mu= -0.8520+/- 0.065 mean_var=265.9767+/-53.819, 0's: 0 Z-trim(112.5): 13 B-trim: 0 in 0/53 Lambda= 0.078642 statistics sampled from 13220 (13225) to 13220 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.406), width: 16 Scan time: 3.640 The best scores are: opt bits E(32554) CCDS43607.1 RSBN1L gene_id:222194|Hs108|chr7 ( 846) 5625 652.0 1.3e-186 CCDS862.1 RSBN1 gene_id:54665|Hs108|chr1 ( 802) 2205 263.9 7.9e-70 >>CCDS43607.1 RSBN1L gene_id:222194|Hs108|chr7 (846 aa) initn: 5625 init1: 5625 opt: 5625 Z-score: 3463.9 bits: 652.0 E(32554): 1.3e-186 Smith-Waterman score: 5625; 100.0% identity (100.0% similar) in 846 aa overlap (1-846:1-846) 10 20 30 40 50 60 pF1KE2 MAEPPSPVHCVAAAAPTATVSEKEPFGKLQLSSRDPPGSLSAKKVRTEEKKAPRRVNGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MAEPPSPVHCVAAAAPTATVSEKEPFGKLQLSSRDPPGSLSAKKVRTEEKKAPRRVNGEG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GSGGNSRQLQPPAAPSPQSYGSPASWSFAPLSAAPSPSSSRSSFSFSAGTAVPSSASASL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GSGGNSRQLQPPAAPSPQSYGSPASWSFAPLSAAPSPSSSRSSFSFSAGTAVPSSASASL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 SQPVPRKLLVPPTLLHAQPHHLLLPAAAAAASANAKSRRPKEKREKERRRHGLGGAREAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SQPVPRKLLVPPTLLHAQPHHLLLPAAAAAASANAKSRRPKEKREKERRRHGLGGAREAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 GASREENGEVKPLPRDKIKDKIKERDKEKEREKKKHKVMNEIKKENGEVKILLKSGKEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 GASREENGEVKPLPRDKIKDKIKERDKEKEREKKKHKVMNEIKKENGEVKILLKSGKEKP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 KTNIEDLQIKKVKKKKKKKHKENEKRKRPKMYSKSIQTICSGLLTDVEDQAAKGILNDNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KTNIEDLQIKKVKKKKKKKHKENEKRKRPKMYSKSIQTICSGLLTDVEDQAAKGILNDNI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KDYVGKNLDTKNYDSKIPENSEFPFVSLKEPRVQNNLKRLDTLEFKQLIHIEHQPNGGAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KDYVGKNLDTKNYDSKIPENSEFPFVSLKEPRVQNNLKRLDTLEFKQLIHIEHQPNGGAS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 VIHAYSNELSHLSPMEMERFAEEFVGLVFSENENSAAFYVMGIVHGAATYLPDFLDYFSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VIHAYSNELSHLSPMEMERFAEEFVGLVFSENENSAAFYVMGIVHGAATYLPDFLDYFSF 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 NFPNSPVKMEILGKKDIETTTMSNFHAQVKRTYSHGTYRAGPMRQISLVGAVDEEVGDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 NFPNSPVKMEILGKKDIETTTMSNFHAQVKRTYSHGTYRAGPMRQISLVGAVDEEVGDYF 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 PEFLDMLEESPFLKCTLPWGTLSSLKLQSRKDSDDGPIMWVRPGEQMIPVADMPKSPFKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PEFLDMLEESPFLKCTLPWGTLSSLKLQSRKDSDDGPIMWVRPGEQMIPVADMPKSPFKR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 KRTTNEIKNLQYLPRTSEPREMLFEDRTRAHADHIGQGFERQTTAAVGVLKAVHCGEWPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KRTTNEIKNLQYLPRTSEPREMLFEDRTRAHADHIGQGFERQTTAAVGVLKAVHCGEWPD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 QPRITKDVICFHAEDFLEVVQRMQLDLHEPPLSQCVQWVDDAKLNQLRREGIRYARIQLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QPRITKDVICFHAEDFLEVVQRMQLDLHEPPLSQCVQWVDDAKLNQLRREGIRYARIQLY 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 DNDIYFIPRNVVHQFKTVSAVCSLAWHIRLKLYHSEEDTSQNTATHETGTSSDSTSSVLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DNDIYFIPRNVVHQFKTVSAVCSLAWHIRLKLYHSEEDTSQNTATHETGTSSDSTSSVLG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 PHTDNMICAVSKASLDSVFSDKLHSKYELQQIKHEPIASVRIKEEPVNVNIPEKTTALNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PHTDNMICAVSKASLDSVFSDKLHSKYELQQIKHEPIASVRIKEEPVNVNIPEKTTALNN 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 MDGKNVKAKLDHVQFAEFKIDMDSKFENSNKDLKEELCPGNLSLVDTRQHSSAHSNQDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MDGKNVKAKLDHVQFAEFKIDMDSKFENSNKDLKEELCPGNLSLVDTRQHSSAHSNQDKK 790 800 810 820 830 840 pF1KE2 DDDILC :::::: CCDS43 DDDILC >>CCDS862.1 RSBN1 gene_id:54665|Hs108|chr1 (802 aa) initn: 2274 init1: 2076 opt: 2205 Z-score: 1367.2 bits: 263.9 E(32554): 7.9e-70 Smith-Waterman score: 2353; 57.2% identity (75.8% similar) in 664 aa overlap (64-706:84-717) 40 50 60 70 80 90 pF1KE2 RDPPGSLSAKKVRTEEKKAPRRVNGEGGSGGNSRQLQPPAAPSPQSYGSPASWSFAPLSA : .:: . .. : .. : :.. :: CCDS86 GAVRVVRAVAAQEEPDKEGKEKPHAGVSPRGVKRQRRSSSGGSQEKRGRPSQE--PPL-- 60 70 80 90 100 100 110 120 130 140 150 pF1KE2 APSPSSSRSSFSFSAGTAVPSSASASLSQPVPRKLLVPP---TLLHAQPHHLLLPAAAAA :: : : : . : :..:. .. :: :: :: .: : : . : : . CCDS86 AP-PHRRRRSRQHP-GPLPPTNAAPTVPGPVEPLLLPPPPPPSLAPAGPA-VAAPLPAPS 110 120 130 140 150 160 160 170 180 190 200 pF1KE2 ASA-------NAKSRRPKEKREKERRRHGLGGAREAGGASREENGEVKPLPRDKIKDKIK .:: .... ::.: .:::..: : .:. : . : .: CCDS86 TSALFTFSPLTVSAAGPKHKGHKERHKHH---------HHRGPDGD----PSSCGTD-LK 170 180 190 200 210 210 220 230 240 250 260 pF1KE2 ERDKEKEREKKKH-KVMNEIKKENGEVKILLKSGKEKPKTNIEDLQIKKVKKKKKKKHKE ..::... :. ... :.:. . ..:: . .:. .::.::::::::.: CCDS86 HKDKQENGERTGGVPLIKAPKRETPD-----ENGKTQ---RADDFVLKKIKKKKKKKHRE 220 230 240 250 260 270 280 290 300 310 pF1KE2 NEKRKRPKMYSKSIQTICSGLLTDVEDQAAKGILNDN----------IKDYVGKNLDTKN . . .: :::.: .::.:.:: .. ..: .:.. .:: :. CCDS86 DMRGRRLKMYNKEVQTVCAGLTRISKEILTQGQINSTSGLNKESFRYLKDEQLCRLNLGM 270 280 290 300 310 320 320 330 340 350 360 370 pF1KE2 YDSKIPENSEFPFVSLKEPRVQNNLKRLDTLEFKQLIHIEHQPNGGASVIHAYSNELSHL . ..:.. . ::.. .: .. :. . : .:...:: ::: :::: :.::: .::: : CCDS86 QEYRVPQGVQTPFMTHQEHSIRRNFLKTGT-KFSNFIHEEHQSNGGALVLHAYMDELSFL 330 340 350 360 370 380 380 390 400 410 420 430 pF1KE2 SPMEMERFAEEFVGLVFSENENSAAFYVMGIVHGAATYLPDFLDYFSFNFPNSPVKMEIL ::::::::.:::..:.:::::..::.:...::::::.:::::::::.:::::.::::::: CCDS86 SPMEMERFSEEFLALTFSENEKNAAYYALAIVHGAAAYLPDFLDYFAFNFPNTPVKMEIL 390 400 410 420 430 440 440 450 460 470 480 490 pF1KE2 GKKDIETTTMSNFHAQVKRTYSHGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPF :::::::::.::::.::.::: ::::::::::::::::::::::::::::::::::::: CCDS86 GKKDIETTTISNFHTQVNRTYCCGTYRAGPMRQISLVGAVDEEVGDYFPEFLDMLEESPF 450 460 470 480 490 500 500 510 520 530 540 550 pF1KE2 LKCTLPWGTLSSLKLQSRKDSDDGPIMWVRPGEQMIPVADMPKSPFKRKRTTNEIKNLQY :: ::::::::::.:: :..:::::::::::::::::.::::::::::.:. :::::::: CCDS86 LKMTLPWGTLSSLRLQCRSQSDDGPIMWVRPGEQMIPTADMPKSPFKRRRSMNEIKNLQY 510 520 530 540 550 560 560 570 580 590 600 610 pF1KE2 LPRTSEPREMLFEDRTRAHADHIGQGFERQTTAAVGVLKAVHCGEWPDQPRITKDVICFH :::::::::.::::::::::::.::::. :.::::::::::. ::: ::::::::::::: CCDS86 LPRTSEPREVLFEDRTRAHADHVGQGFDWQSTAAVGVLKAVQFGEWSDQPRITKDVICFH 570 580 590 600 610 620 620 630 640 650 660 670 pF1KE2 AEDFLEVVQRMQLDLHEPPLSQCVQWVDDAKLNQLRREGIRYARIQLYDNDIYFIPRNVV :::: .::::.::::::::.::::::::.:::::.:::::::::::: :::::::::::. CCDS86 AEDFTDVVQRLQLDLHEPPVSQCVQWVDEAKLNQMRREGIRYARIQLCDNDIYFIPRNVI 630 640 650 660 670 680 680 690 700 710 720 730 pF1KE2 HQFKTVSAVCSLAWHIRLKLYHSEEDTSQNTATHETGTSSDSTSSVLGPHTDNMICAVSK ::::::::::::::::::: :: ...::: .. CCDS86 HQFKTVSAVCSLAWHIRLKQYHPVVEATQNTESNSNMDCGLTGKRELEVDSQCVRIKTES 690 700 710 720 730 740 740 750 760 770 780 790 pF1KE2 ASLDSVFSDKLHSKYELQQIKHEPIASVRIKEEPVNVNIPEKTTALNNMDGKNVKAKLDH CCDS86 EEACTEIQLLTTASSSFPPASELNLQQDQKTQPIPVLKVESRLDSDQQHNLQEHSTTSV 750 760 770 780 790 800 846 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:59:02 2016 done: Sat Nov 5 14:59:03 2016 Total Scan time: 3.640 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]