FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2484, 2377 aa 1>>>pF1KE2484 2377 - 2377 aa - 2377 aa Library: human.CCDS.faa 18921897 residues in 33420 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1198+/-0.00104; mu= 4.3765+/- 0.062 mean_var=265.6260+/-53.433, 0's: 0 Z-trim(113.4): 112 B-trim: 0 in 0/51 Lambda= 0.078694 statistics sampled from 14158 (14267) to 14158 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.427), width: 16 Scan time: 3.950 The best scores are: opt bits E(33420) CCDS45730.1 CACNA1G gene_id:8913|Hs109|chr17 (2377) 16093 1842.1 0 CCDS45731.1 CACNA1G gene_id:8913|Hs109|chr17 (2332) 13306 1525.7 0 CCDS45732.1 CACNA1G gene_id:8913|Hs109|chr17 (2284) 13019 1493.1 0 CCDS58569.1 CACNA1G gene_id:8913|Hs109|chr17 (2291) 13003 1491.3 0 CCDS58566.1 CACNA1G gene_id:8913|Hs109|chr17 (2205) 12974 1488.0 0 CCDS58565.1 CACNA1G gene_id:8913|Hs109|chr17 (2277) 12900 1479.6 0 CCDS58570.1 CACNA1G gene_id:8913|Hs109|chr17 (2366) 10698 1229.6 0 CCDS58571.1 CACNA1G gene_id:8913|Hs109|chr17 (2194) 10676 1227.1 0 CCDS54143.1 CACNA1G gene_id:8913|Hs109|chr17 (2273) 10676 1227.1 0 CCDS54142.1 CACNA1G gene_id:8913|Hs109|chr17 (2321) 10665 1225.9 0 CCDS58567.1 CACNA1G gene_id:8913|Hs109|chr17 (2259) 10598 1218.2 0 CCDS45733.1 CACNA1G gene_id:8913|Hs109|chr17 (2266) 10598 1218.2 0 CCDS58568.1 CACNA1G gene_id:8913|Hs109|chr17 (2314) 10598 1218.3 0 CCDS58573.1 CACNA1G gene_id:8913|Hs109|chr17 (2232) 10157 1168.2 0 CCDS58575.1 CACNA1G gene_id:8913|Hs109|chr17 (2239) 10157 1168.2 0 CCDS58572.1 CACNA1G gene_id:8913|Hs109|chr17 (2250) 10157 1168.2 0 CCDS58574.1 CACNA1G gene_id:8913|Hs109|chr17 (2287) 10157 1168.2 0 CCDS45736.1 CACNA1G gene_id:8913|Hs109|chr17 (2171) 6627 767.4 0 CCDS58576.1 CACNA1G gene_id:8913|Hs109|chr17 (2227) 6627 767.4 0 CCDS54145.1 CACNA1G gene_id:8913|Hs109|chr17 (2243) 6627 767.4 0 CCDS45735.1 CACNA1G gene_id:8913|Hs109|chr17 (2250) 6627 767.4 0 CCDS54144.1 CACNA1G gene_id:8913|Hs109|chr17 (2261) 6627 767.4 0 CCDS54146.1 CACNA1G gene_id:8913|Hs109|chr17 (2298) 6627 767.4 0 CCDS45737.1 CACNA1G gene_id:8913|Hs109|chr17 (2306) 6627 767.4 0 CCDS45734.1 CACNA1G gene_id:8913|Hs109|chr17 (2343) 6627 767.4 0 CCDS45375.1 CACNA1H gene_id:8912|Hs109|chr16 (2353) 4121 482.9 7.9e-135 CCDS45376.1 CACNA1H gene_id:8912|Hs109|chr16 (2347) 4119 482.7 9.2e-135 CCDS46711.1 CACNA1I gene_id:8911|Hs109|chr22 (2188) 3235 382.3 1.4e-104 CCDS46710.1 CACNA1I gene_id:8911|Hs109|chr22 (2223) 3227 381.4 2.7e-104 CCDS44797.1 CACNA1C gene_id:775|Hs109|chr12 (2155) 801 106.0 2.2e-21 CCDS1407.1 CACNA1S gene_id:779|Hs109|chr1 (1873) 714 96.1 1.8e-18 CCDS44787.1 CACNA1C gene_id:775|Hs109|chr12 (2138) 686 92.9 1.8e-17 CCDS44800.1 CACNA1C gene_id:775|Hs109|chr12 (2138) 686 92.9 1.8e-17 CCDS44799.1 CACNA1C gene_id:775|Hs109|chr12 (2157) 686 92.9 1.8e-17 CCDS53736.1 CACNA1C gene_id:775|Hs109|chr12 (2173) 686 92.9 1.8e-17 CCDS44798.1 CACNA1C gene_id:775|Hs109|chr12 (2138) 681 92.3 2.7e-17 CCDS44794.1 CACNA1C gene_id:775|Hs109|chr12 (2138) 677 91.9 3.7e-17 CCDS44793.1 CACNA1C gene_id:775|Hs109|chr12 (2157) 677 91.9 3.7e-17 CCDS53734.1 CACNA1C gene_id:775|Hs109|chr12 (2138) 672 91.3 5.5e-17 CCDS44791.1 CACNA1C gene_id:775|Hs109|chr12 (2138) 672 91.3 5.5e-17 CCDS53735.1 CACNA1C gene_id:775|Hs109|chr12 (2157) 672 91.3 5.5e-17 CCDS53733.1 CACNA1C gene_id:775|Hs109|chr12 (2173) 672 91.3 5.6e-17 CCDS46848.1 CACNA1D gene_id:776|Hs109|chr3 (2161) 599 83.0 1.7e-14 CCDS2872.1 CACNA1D gene_id:776|Hs109|chr3 (2181) 599 83.0 1.7e-14 CCDS54413.1 SCN1A gene_id:6323|Hs109|chr2 (2009) 590 82.0 3.3e-14 CCDS44790.1 CACNA1C gene_id:775|Hs109|chr12 (2166) 578 80.7 9e-14 CCDS53794.1 SCN8A gene_id:6334|Hs109|chr12 (1939) 568 79.5 1.8e-13 CCDS44891.1 SCN8A gene_id:6334|Hs109|chr12 (1980) 568 79.5 1.8e-13 CCDS81692.1 SCN8A gene_id:6334|Hs109|chr12 (1980) 568 79.5 1.8e-13 CCDS33737.1 SCN11A gene_id:11280|Hs109|chr3 (1791) 554 77.9 5.1e-13 >>CCDS45730.1 CACNA1G gene_id:8913|Hs109|chr17 (2377 aa) initn: 16093 init1: 16093 opt: 16093 Z-score: 9879.9 bits: 1842.1 E(33420): 0 Smith-Waterman score: 16093; 100.0% identity (100.0% similar) in 2377 aa overlap (1-2377:1-2377) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2290 2300 2310 2320 2330 2340 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS45 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2350 2360 2370 >>CCDS45731.1 CACNA1G gene_id:8913|Hs109|chr17 (2332 aa) initn: 13289 init1: 13289 opt: 13306 Z-score: 8170.0 bits: 1525.7 E(33420): 0 Smith-Waterman score: 15717; 98.1% identity (98.1% similar) in 2377 aa overlap (1-2377:1-2332) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQ----- 1930 1940 1950 1960 1970 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::: CCDS45 ----------------------------------------MQPHPTELPGPDLLTVRKSG 1980 1990 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 2000 2010 2020 2030 2040 2050 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS 2060 2070 2080 2090 2100 2110 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE 2120 2130 2140 2150 2160 2170 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2180 2190 2200 2210 2220 2230 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2240 2250 2260 2270 2280 2290 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS45 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2300 2310 2320 2330 >>CCDS45732.1 CACNA1G gene_id:8913|Hs109|chr17 (2284 aa) initn: 15476 init1: 12960 opt: 13019 Z-score: 7994.0 bits: 1493.1 E(33420): 0 Smith-Waterman score: 15294; 96.1% identity (96.1% similar) in 2377 aa overlap (1-2377:1-2284) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE ::::::: CCDS45 FSLEHPT----------------------------------------------------- 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::: CCDS45 ----------------------------------------MQPHPTELPGPDLLTVRKSG 1930 1940 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 1950 1960 1970 1980 1990 2000 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS 2010 2020 2030 2040 2050 2060 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE 2070 2080 2090 2100 2110 2120 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2130 2140 2150 2160 2170 2180 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2190 2200 2210 2220 2230 2240 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS45 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2250 2260 2270 2280 >>CCDS58569.1 CACNA1G gene_id:8913|Hs109|chr17 (2291 aa) initn: 13109 init1: 10593 opt: 13003 Z-score: 7984.2 bits: 1491.3 E(33420): 0 Smith-Waterman score: 15265; 95.8% identity (95.8% similar) in 2384 aa overlap (1-2377:1-2291) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 pF1KE2 RRLEKKRR-------NLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYL :::::::: .:::::::::::::::::::::::::::::::::::::::::::: CCDS58 RRLEKKRRSKEKQMADLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYL 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE2 DLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQD 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KE2 RWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALL 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KE2 DTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFL 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KE2 TLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKH 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KE2 LEESNKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LEESNKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAA 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KE2 HARSASHFSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSD :::::::::::::: CCDS58 HARSASHFSLEHPT---------------------------------------------- 1930 1980 1990 2000 2010 2020 2030 pF1KE2 PQIPLAEMEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDL ::::::::::::: CCDS58 -----------------------------------------------MQPHPTELPGPDL 1940 2040 2050 2060 2070 2080 2090 pF1KE2 LTVRKSGVSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LTVRKSGVSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYIL 1950 1960 1970 1980 1990 2000 2100 2110 2120 2130 2140 2150 pF1KE2 QLPKDAPHLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 QLPKDAPHLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLL 2010 2020 2030 2040 2050 2060 2160 2170 2180 2190 2200 2210 pF1KE2 AEVSGPSPPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AEVSGPSPPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRS 2070 2080 2090 2100 2110 2120 2220 2230 2240 2250 2260 2270 pF1KE2 SLELDTELSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SLELDTELSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVS 2130 2140 2150 2160 2170 2180 2280 2290 2300 2310 2320 2330 pF1KE2 CLDSGSQPHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CLDSGSQPHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRR 2190 2200 2210 2220 2230 2240 2340 2350 2360 2370 pF1KE2 RAPSSDSKDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP :::::::::::::::::::::::::::::::::::::::::::: CCDS58 RAPSSDSKDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2250 2260 2270 2280 2290 >>CCDS58566.1 CACNA1G gene_id:8913|Hs109|chr17 (2205 aa) initn: 13961 init1: 12960 opt: 12974 Z-score: 7966.6 bits: 1488.0 E(33420): 0 Smith-Waterman score: 14550; 92.8% identity (92.8% similar) in 2377 aa overlap (1-2377:1-2205) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE ::::::: CCDS58 FSLEHPT----------------------------------------------------- 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::: CCDS58 ----------------------------------------MQPHPTELPGPDLLTVRKSG 1930 1940 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 1950 1960 1970 1980 1990 2000 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAE----- 2010 2020 2030 2040 2050 2060 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE CCDS58 ------------------------------------------------------------ 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::: CCDS58 --------------EEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2070 2080 2090 2100 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2110 2120 2130 2140 2150 2160 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS58 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2170 2180 2190 2200 >>CCDS58565.1 CACNA1G gene_id:8913|Hs109|chr17 (2277 aa) initn: 14179 init1: 11663 opt: 12900 Z-score: 7921.0 bits: 1479.6 E(33420): 0 Smith-Waterman score: 15224; 95.8% identity (95.8% similar) in 2377 aa overlap (1-2377:1-2277) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTV---- 1690 1700 1710 1720 1730 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ---GNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1740 1750 1760 1770 1780 1790 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1800 1810 1820 1830 1840 1850 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1860 1870 1880 1890 1900 1910 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE ::::::: CCDS58 FSLEHPT----------------------------------------------------- 1920 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::: CCDS58 ----------------------------------------MQPHPTELPGPDLLTVRKSG 1930 1940 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 1950 1960 1970 1980 1990 2000 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS 2010 2020 2030 2040 2050 2060 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE 2070 2080 2090 2100 2110 2120 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2130 2140 2150 2160 2170 2180 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2190 2200 2210 2220 2230 2240 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS58 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2250 2260 2270 >>CCDS58570.1 CACNA1G gene_id:8913|Hs109|chr17 (2366 aa) initn: 10593 init1: 10593 opt: 10698 Z-score: 6569.7 bits: 1229.6 E(33420): 0 Smith-Waterman score: 15961; 99.3% identity (99.4% similar) in 2377 aa overlap (1-2377:1-2366) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::: :. . .:::::::::::::::::::::::::::::::::: CCDS58 RRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1610 1620 1630 1640 1650 1660 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1670 1680 1690 1700 1710 1720 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1730 1740 1750 1760 1770 1780 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1790 1800 1810 1820 1830 1840 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1850 1860 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE 1910 1920 1930 1940 1950 1960 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG 1970 1980 1990 2000 2010 2020 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 2030 2040 2050 2060 2070 2080 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS 2090 2100 2110 2120 2130 2140 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE 2150 2160 2170 2180 2190 2200 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2210 2220 2230 2240 2250 2260 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2270 2280 2290 2300 2310 2320 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS58 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2330 2340 2350 2360 >>CCDS58571.1 CACNA1G gene_id:8913|Hs109|chr17 (2194 aa) initn: 11594 init1: 10593 opt: 10676 Z-score: 6556.7 bits: 1227.1 E(33420): 0 Smith-Waterman score: 14418; 92.0% identity (92.2% similar) in 2377 aa overlap (1-2377:1-2194) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::: :. . .:::::::::::::::::::::::::::::::::: CCDS58 RRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1610 1620 1630 1640 1650 1660 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1670 1680 1690 1700 1710 1720 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1730 1740 1750 1760 1770 1780 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1790 1800 1810 1820 1830 1840 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1850 1860 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE ::::::: CCDS58 FSLEHPT----------------------------------------------------- 1910 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::: CCDS58 ----------------------------------------MQPHPTELPGPDLLTVRKSG 1920 1930 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 1940 1950 1960 1970 1980 1990 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAE----- 2000 2010 2020 2030 2040 2050 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE CCDS58 ------------------------------------------------------------ 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::: CCDS58 --------------EEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2060 2070 2080 2090 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2100 2110 2120 2130 2140 2150 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS58 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2160 2170 2180 2190 >>CCDS54143.1 CACNA1G gene_id:8913|Hs109|chr17 (2273 aa) initn: 13109 init1: 10593 opt: 10676 Z-score: 6556.4 bits: 1227.1 E(33420): 0 Smith-Waterman score: 15162; 95.4% identity (95.5% similar) in 2377 aa overlap (1-2377:1-2273) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::: :. . .:::::::::::::::::::::::::::::::::: CCDS54 RRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1610 1620 1630 1640 1650 1660 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1670 1680 1690 1700 1710 1720 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1730 1740 1750 1760 1770 1780 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1790 1800 1810 1820 1830 1840 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1850 1860 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE ::::::: CCDS54 FSLEHPT----------------------------------------------------- 1910 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::: CCDS54 ----------------------------------------MQPHPTELPGPDLLTVRKSG 1920 1930 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 1940 1950 1960 1970 1980 1990 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS 2000 2010 2020 2030 2040 2050 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE 2060 2070 2080 2090 2100 2110 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2120 2130 2140 2150 2160 2170 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2180 2190 2200 2210 2220 2230 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS54 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2240 2250 2260 2270 >>CCDS54142.1 CACNA1G gene_id:8913|Hs109|chr17 (2321 aa) initn: 13112 init1: 10593 opt: 10665 Z-score: 6549.6 bits: 1225.9 E(33420): 0 Smith-Waterman score: 15585; 97.4% identity (97.5% similar) in 2377 aa overlap (1-2377:1-2321) 10 20 30 40 50 60 pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV :::::::: :. . .:::::::::::::::::::::::::::::::::: CCDS54 RRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL 1610 1620 1630 1640 1650 1660 1690 1700 1710 1720 1730 1740 pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL 1670 1680 1690 1700 1710 1720 1750 1760 1770 1780 1790 1800 pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST 1730 1740 1750 1760 1770 1780 1810 1820 1830 1840 1850 1860 pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE 1790 1800 1810 1820 1830 1840 1870 1880 1890 1900 1910 1920 pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH 1850 1860 1870 1880 1890 1900 1930 1940 1950 1960 1970 1980 pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQ----- 1910 1920 1930 1940 1950 1960 1990 2000 2010 2020 2030 2040 pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG :::::::::::::::::::: CCDS54 ----------------------------------------MQPHPTELPGPDLLTVRKSG 1970 1980 2050 2060 2070 2080 2090 2100 pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP 1990 2000 2010 2020 2030 2040 2110 2120 2130 2140 2150 2160 pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS 2050 2060 2070 2080 2090 2100 2170 2180 2190 2200 2210 2220 pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE 2110 2120 2130 2140 2150 2160 2230 2240 2250 2260 2270 2280 pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ 2170 2180 2190 2200 2210 2220 2290 2300 2310 2320 2330 2340 pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS 2230 2240 2250 2260 2270 2280 2350 2360 2370 pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP ::::::::::::::::::::::::::::::::::::: CCDS54 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP 2290 2300 2310 2320 2377 residues in 1 query sequences 18921897 residues in 33420 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Jul 18 21:06:46 2019 done: Thu Jul 18 21:06:47 2019 Total Scan time: 3.950 Total Display time: 1.350 Function used was FASTA [36.3.4 Apr, 2011]