Result of FASTA (omim) for
pF1KE2484
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2484, 2377 aa
1>>>pF1KE2484 2377 - 2377 aa - 2377 aa
Library: /omim/omim.rfq.tfa
64092750 residues in 91774 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4375+/-0.000396; mu= 2.7362+/- 0.025
mean_var=303.0895+/-62.925, 0's: 0 Z-trim(121.5): 243 B-trim: 17 in 1/52
Lambda= 0.073670
statistics sampled from 39341 (39601) to 39341 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.432), width: 16
Scan time: 12.880
The best scores are: opt bits E(91774)
NP_061496 (OMIM: 604065,616795,618087) voltage-dep (2377) 16093 1726.0 0
NP_938199 (OMIM: 604065,616795,618087) voltage-dep (2332) 13306 1429.8 0
NP_938198 (OMIM: 604065,616795,618087) voltage-dep (2284) 13019 1399.2 0
NP_001243254 (OMIM: 604065,616795,618087) voltage- (2291) 13003 1397.5 0
NP_001243262 (OMIM: 604065,616795,618087) voltage- (2205) 12974 1394.5 0
NP_001243256 (OMIM: 604065,616795,618087) voltage- (2277) 12900 1386.6 0
NP_938191 (OMIM: 604065,616795,618087) voltage-dep (2366) 10698 1152.6 0
NP_001243263 (OMIM: 604065,616795,618087) voltage- (2194) 10676 1150.2 0
NP_938192 (OMIM: 604065,616795,618087) voltage-dep (2273) 10676 1150.2 0
NP_938194 (OMIM: 604065,616795,618087) voltage-dep (2321) 10665 1149.1 0
NP_001243257 (OMIM: 604065,616795,618087) voltage- (2259) 10598 1141.9 0
NP_938200 (OMIM: 604065,616795,618087) voltage-dep (2266) 10598 1141.9 0
NP_001243253 (OMIM: 604065,616795,618087) voltage- (2314) 10598 1141.9 0
NP_001243260 (OMIM: 604065,616795,618087) voltage- (2232) 10157 1095.1 0
NP_001243259 (OMIM: 604065,616795,618087) voltage- (2239) 10157 1095.1 0
NP_001243290 (OMIM: 604065,616795,618087) voltage- (2246) 10157 1095.1 0
NP_001243289 (OMIM: 604065,616795,618087) voltage- (2248) 10157 1095.1 0
NP_001243258 (OMIM: 604065,616795,618087) voltage- (2250) 10157 1095.1 0
NP_001243288 (OMIM: 604065,616795,618087) voltage- (2257) 10157 1095.1 0
NP_001243255 (OMIM: 604065,616795,618087) voltage- (2287) 10157 1095.1 0
NP_938190 (OMIM: 604065,616795,618087) voltage-dep (2171) 6627 719.9 9.4e-206
NP_001243261 (OMIM: 604065,616795,618087) voltage- (2227) 6627 719.9 9.6e-206
NP_938202 (OMIM: 604065,616795,618087) voltage-dep (2243) 6627 719.9 9.7e-206
NP_938201 (OMIM: 604065,616795,618087) voltage-dep (2250) 6627 719.9 9.7e-206
NP_938196 (OMIM: 604065,616795,618087) voltage-dep (2261) 6627 719.9 9.7e-206
XP_006722223 (OMIM: 604065,616795,618087) voltage- (2268) 6627 719.9 9.7e-206
NP_938193 (OMIM: 604065,616795,618087) voltage-dep (2298) 6627 719.9 9.8e-206
NP_938197 (OMIM: 604065,616795,618087) voltage-dep (2306) 6627 719.9 9.9e-206
NP_938406 (OMIM: 604065,616795,618087) voltage-dep (2343) 6627 719.9 1e-205
XP_006722224 (OMIM: 604065,616795,618087) voltage- (2244) 6274 682.4 1.9e-194
XP_006721026 (OMIM: 607904,611942,617027) voltage- (2358) 5664 617.5 6.5e-175
XP_005255709 (OMIM: 607904,611942,617027) voltage- (2347) 5623 613.2 1.3e-173
XP_016879308 (OMIM: 607904,611942,617027) voltage- (2345) 5162 564.2 7.4e-159
XP_011521026 (OMIM: 607904,611942,617027) voltage- (2176) 4945 541.1 6.2e-152
NP_066921 (OMIM: 607904,611942,617027) voltage-dep (2353) 4121 453.5 1.5e-125
XP_006721028 (OMIM: 607904,611942,617027) voltage- (2336) 4119 453.3 1.7e-125
NP_001005407 (OMIM: 607904,611942,617027) voltage- (2347) 4119 453.3 1.7e-125
XP_016879309 (OMIM: 607904,611942,617027) voltage- (1691) 4101 451.3 5.1e-125
XP_016879310 (OMIM: 607904,611942,617027) voltage- (1691) 4101 451.3 5.1e-125
XP_006721027 (OMIM: 607904,611942,617027) voltage- (2342) 4101 451.4 6.6e-125
XP_006721031 (OMIM: 607904,611942,617027) voltage- (1612) 3690 407.6 6.9e-112
XP_006721030 (OMIM: 607904,611942,617027) voltage- (1618) 3690 407.6 7e-112
NP_001003406 (OMIM: 608230) voltage-dependent T-ty (2188) 3235 359.4 3.2e-97
NP_066919 (OMIM: 608230) voltage-dependent T-type (2223) 3227 358.5 5.8e-97
XP_016884526 (OMIM: 608230) voltage-dependent T-ty (1593) 3049 339.5 2.2e-91
XP_016884525 (OMIM: 608230) voltage-dependent T-ty (1605) 3049 339.5 2.2e-91
XP_016884524 (OMIM: 608230) voltage-dependent T-ty (1606) 3049 339.5 2.2e-91
XP_011521029 (OMIM: 607904,611942,617027) voltage- (1283) 2417 272.2 3.1e-71
NP_001123308 (OMIM: 114205,601005,611875) voltage- (2155) 801 100.7 2.3e-19
XP_016875428 (OMIM: 114205,601005,611875) voltage- (2211) 801 100.7 2.4e-19
>>NP_061496 (OMIM: 604065,616795,618087) voltage-depende (2377 aa)
initn: 16093 init1: 16093 opt: 16093 Z-score: 9252.2 bits: 1726.0 E(91774): 0
Smith-Waterman score: 16093; 100.0% identity (100.0% similar) in 2377 aa overlap (1-2377:1-2377)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2290 2300 2310 2320 2330 2340
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_061 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2350 2360 2370
>>NP_938199 (OMIM: 604065,616795,618087) voltage-depende (2332 aa)
initn: 13289 init1: 13289 opt: 13306 Z-score: 7651.5 bits: 1429.8 E(91774): 0
Smith-Waterman score: 15717; 98.1% identity (98.1% similar) in 2377 aa overlap (1-2377:1-2332)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQ-----
1930 1940 1950 1960 1970
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::
NP_938 ----------------------------------------MQPHPTELPGPDLLTVRKSG
1980 1990
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
2000 2010 2020 2030 2040 2050
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
2060 2070 2080 2090 2100 2110
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
2120 2130 2140 2150 2160 2170
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2180 2190 2200 2210 2220 2230
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2240 2250 2260 2270 2280 2290
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_938 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2300 2310 2320 2330
>>NP_938198 (OMIM: 604065,616795,618087) voltage-depende (2284 aa)
initn: 15476 init1: 12960 opt: 13019 Z-score: 7486.7 bits: 1399.2 E(91774): 0
Smith-Waterman score: 15294; 96.1% identity (96.1% similar) in 2377 aa overlap (1-2377:1-2284)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
:::::::
NP_938 FSLEHPT-----------------------------------------------------
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::
NP_938 ----------------------------------------MQPHPTELPGPDLLTVRKSG
1930 1940
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
1950 1960 1970 1980 1990 2000
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
2010 2020 2030 2040 2050 2060
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
2070 2080 2090 2100 2110 2120
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2130 2140 2150 2160 2170 2180
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2190 2200 2210 2220 2230 2240
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_938 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2250 2260 2270 2280
>>NP_001243254 (OMIM: 604065,616795,618087) voltage-depe (2291 aa)
initn: 13109 init1: 10593 opt: 13003 Z-score: 7477.5 bits: 1397.5 E(91774): 0
Smith-Waterman score: 15265; 95.8% identity (95.8% similar) in 2384 aa overlap (1-2377:1-2291)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610
pF1KE2 RRLEKKRR-------NLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYL
:::::::: .::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRLEKKRRSKEKQMADLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYL
1570 1580 1590 1600 1610 1620
1620 1630 1640 1650 1660 1670
pF1KE2 DLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLFITGVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQD
1630 1640 1650 1660 1670 1680
1680 1690 1700 1710 1720 1730
pF1KE2 RWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RWNQLDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALL
1690 1700 1710 1720 1730 1740
1740 1750 1760 1770 1780 1790
pF1KE2 DTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTVMQALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFL
1750 1760 1770 1780 1790 1800
1800 1810 1820 1830 1840 1850
pF1KE2 TLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLFRVSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKH
1810 1820 1830 1840 1850 1860
1860 1870 1880 1890 1900 1910
pF1KE2 LEESNKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEESNKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAA
1870 1880 1890 1900 1910 1920
1920 1930 1940 1950 1960 1970
pF1KE2 HARSASHFSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSD
::::::::::::::
NP_001 HARSASHFSLEHPT----------------------------------------------
1930
1980 1990 2000 2010 2020 2030
pF1KE2 PQIPLAEMEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDL
:::::::::::::
NP_001 -----------------------------------------------MQPHPTELPGPDL
1940
2040 2050 2060 2070 2080 2090
pF1KE2 LTVRKSGVSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTVRKSGVSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYIL
1950 1960 1970 1980 1990 2000
2100 2110 2120 2130 2140 2150
pF1KE2 QLPKDAPHLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLPKDAPHLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLL
2010 2020 2030 2040 2050 2060
2160 2170 2180 2190 2200 2210
pF1KE2 AEVSGPSPPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEVSGPSPPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRS
2070 2080 2090 2100 2110 2120
2220 2230 2240 2250 2260 2270
pF1KE2 SLELDTELSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLELDTELSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVS
2130 2140 2150 2160 2170 2180
2280 2290 2300 2310 2320 2330
pF1KE2 CLDSGSQPHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLDSGSQPHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRR
2190 2200 2210 2220 2230 2240
2340 2350 2360 2370
pF1KE2 RAPSSDSKDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAPSSDSKDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2250 2260 2270 2280 2290
>>NP_001243262 (OMIM: 604065,616795,618087) voltage-depe (2205 aa)
initn: 13961 init1: 12960 opt: 12974 Z-score: 7461.1 bits: 1394.5 E(91774): 0
Smith-Waterman score: 14550; 92.8% identity (92.8% similar) in 2377 aa overlap (1-2377:1-2205)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
:::::::
NP_001 FSLEHPT-----------------------------------------------------
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::
NP_001 ----------------------------------------MQPHPTELPGPDLLTVRKSG
1930 1940
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
1950 1960 1970 1980 1990 2000
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAE-----
2010 2020 2030 2040 2050 2060
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
NP_001 ------------------------------------------------------------
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------EEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2070 2080 2090 2100
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2110 2120 2130 2140 2150 2160
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_001 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2170 2180 2190 2200
>>NP_001243256 (OMIM: 604065,616795,618087) voltage-depe (2277 aa)
initn: 14179 init1: 11663 opt: 12900 Z-score: 7418.4 bits: 1386.6 E(91774): 0
Smith-Waterman score: 15224; 95.8% identity (95.8% similar) in 2377 aa overlap (1-2377:1-2277)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTV----
1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---GNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1860 1870 1880 1890 1900 1910
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
:::::::
NP_001 FSLEHPT-----------------------------------------------------
1920
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::
NP_001 ----------------------------------------MQPHPTELPGPDLLTVRKSG
1930 1940
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
1950 1960 1970 1980 1990 2000
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
2010 2020 2030 2040 2050 2060
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
2070 2080 2090 2100 2110 2120
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2130 2140 2150 2160 2170 2180
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2190 2200 2210 2220 2230 2240
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_001 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2250 2260 2270
>>NP_938191 (OMIM: 604065,616795,618087) voltage-depende (2366 aa)
initn: 10593 init1: 10593 opt: 10698 Z-score: 6153.3 bits: 1152.6 E(91774): 0
Smith-Waterman score: 15961; 99.3% identity (99.4% similar) in 2377 aa overlap (1-2377:1-2366)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
:::::::: :. . .::::::::::::::::::::::::::::::::::
NP_938 RRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
2090 2100 2110 2120 2130 2140
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
2150 2160 2170 2180 2190 2200
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2210 2220 2230 2240 2250 2260
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2270 2280 2290 2300 2310 2320
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_938 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2330 2340 2350 2360
>>NP_001243263 (OMIM: 604065,616795,618087) voltage-depe (2194 aa)
initn: 11594 init1: 10593 opt: 10676 Z-score: 6141.2 bits: 1150.2 E(91774): 0
Smith-Waterman score: 14418; 92.0% identity (92.2% similar) in 2377 aa overlap (1-2377:1-2194)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
:::::::: :. . .::::::::::::::::::::::::::::::::::
NP_001 RRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
:::::::
NP_001 FSLEHPT-----------------------------------------------------
1910
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::
NP_001 ----------------------------------------MQPHPTELPGPDLLTVRKSG
1920 1930
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
1940 1950 1960 1970 1980 1990
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAE-----
2000 2010 2020 2030 2040 2050
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
NP_001 ------------------------------------------------------------
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------EEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2060 2070 2080 2090
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2100 2110 2120 2130 2140 2150
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_001 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2160 2170 2180 2190
>>NP_938192 (OMIM: 604065,616795,618087) voltage-depende (2273 aa)
initn: 13109 init1: 10593 opt: 10676 Z-score: 6140.9 bits: 1150.2 E(91774): 0
Smith-Waterman score: 15162; 95.4% identity (95.5% similar) in 2377 aa overlap (1-2377:1-2273)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
:::::::: :. . .::::::::::::::::::::::::::::::::::
NP_938 RRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
:::::::
NP_938 FSLEHPT-----------------------------------------------------
1910
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::
NP_938 ----------------------------------------MQPHPTELPGPDLLTVRKSG
1920 1930
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
1940 1950 1960 1970 1980 1990
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
2000 2010 2020 2030 2040 2050
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
2060 2070 2080 2090 2100 2110
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2120 2130 2140 2150 2160 2170
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2180 2190 2200 2210 2220 2230
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_938 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2240 2250 2260 2270
>>NP_938194 (OMIM: 604065,616795,618087) voltage-depende (2321 aa)
initn: 13112 init1: 10593 opt: 10665 Z-score: 6134.5 bits: 1149.1 E(91774): 0
Smith-Waterman score: 15585; 97.4% identity (97.5% similar) in 2377 aa overlap (1-2377:1-2321)
10 20 30 40 50 60
pF1KE2 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 MDEEEDGAGAEESGQPRSFMRLNDLSGAGGRPGPGSAEKDPGSADSEAEGLPYPALAPVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FFYLSQDSRPRSWCLRTVCNPWFERISMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CFLPENFSLPLSVDLERYYQTENEDESPFICSQPRENGMRSCRSVPTLRGDGGGGPPCGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DYEAYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAAGVRVGLLSSPAPLGGQETQPSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SCSRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRAPRASPEIQDRDANGSRRLMLPPPSTP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALSGAPPGGAESVHSFYHADCHLEPVRCQAPPPRSPSEASGRTVGSGKVYPTVHTSPPPE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TLKEKALVEVAASSGPPTLTSLNIPPGPYSSMHKLLETQSTGACQSSCKISSPCLKADSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ACGPDSCPYCARAGAGEVELADREMPDSDSEAVYEFTQDAQHSDLRDPHSRRQRSLGPDA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 EPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISNI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLMR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDTL
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLLV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AILVEGFQAEEISKREDASGQLSCIQLPVDSQGGDANKSESEPDFFSPSLDGDGDRKKCL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 ALVSLGEHPELRKSLLPPLIIHTAATPMSLPKSTSTGLGEALGPASRRTSSSGSAEPGAA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQESQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DEEESSEEERASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRGSASEHQDCN
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GKSASGRLARALRPDDPPLDGDDADDEGNLSKGERVRAWIRARLPACCLERDSWSAYIFP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFTAV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLRVL
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 RLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKFFV
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 CQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDAVG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEKRL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
:::::::: :. . .::::::::::::::::::::::::::::::::::
NP_938 RRLEKKRR-----------SKEKQMAEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFITGV
1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE2 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 IGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFVLESVFKLVAFGFRRFFQDRWNQLDL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KE2 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVMQAL
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KE2 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFRVST
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KE2 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEESNKE
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KE2 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 AKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGPDSPDSPKPGALHPAAHARSASH
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KE2 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQIPLAE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 FSLEHPTDRQLFDTISLLIQGSLEWELKLMDELAGPGGQPSAFPSAPSLGGSDPQ-----
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KE2 MEALSLTSEIVSEPSCSLALTDDSLPDDMHTLLLSALESNMQPHPTELPGPDLLTVRKSG
::::::::::::::::::::
NP_938 ----------------------------------------MQPHPTELPGPDLLTVRKSG
1970 1980
2050 2060 2070 2080 2090 2100
pF1KE2 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 VSRTHSLPNDSYMCRHGSTAEGPLGHRGWGLPKAQSGSVLSVHSQPADTSYILQLPKDAP
1990 2000 2010 2020 2030 2040
2110 2120 2130 2140 2150 2160
pF1KE2 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 HLLQPHSAPTWGTIPKLPPPGRSPLAQRPLRRQAAIRTDSLDVQGLGSREDLLAEVSGPS
2050 2060 2070 2080 2090 2100
2170 2180 2190 2200 2210 2220
pF1KE2 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PPLARAYSFWGQSSTQAQQHSRSHSKISKHMTPPAPCPGPEPNWGKGPPETRSSLELDTE
2110 2120 2130 2140 2150 2160
2230 2240 2250 2260 2270 2280
pF1KE2 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LSWISGDLLPPGGQEEPPSPRDLKKCYSVEAQSCQRRPTSWLDEQRRHSIAVSCLDSGSQ
2170 2180 2190 2200 2210 2220
2290 2300 2310 2320 2330 2340
pF1KE2 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PHLGTDPSNLGGQPLGGPGSRPKKKLSPPSITIDPPESQGPRTPPSPGICLRRRAPSSDS
2230 2240 2250 2260 2270 2280
2350 2360 2370
pF1KE2 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
:::::::::::::::::::::::::::::::::::::
NP_938 KDPLASGPPDSMAASPSPKKDVLSLSGLSSDPADLDP
2290 2300 2310 2320
2377 residues in 1 query sequences
64092750 residues in 91774 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Jul 18 21:06:47 2019 done: Thu Jul 18 21:06:49 2019
Total Scan time: 12.880 Total Display time: 1.330
Function used was FASTA [36.3.4 Apr, 2011]