FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2491, 2353 aa 1>>>pF1KE2491 2353 - 2353 aa - 2353 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.6361+/-0.000415; mu= 1.4285+/- 0.026 mean_var=317.1077+/-66.692, 0's: 0 Z-trim(121.4): 275 B-trim: 590 in 1/57 Lambda= 0.072023 statistics sampled from 37561 (37844) to 37561 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.444), width: 16 Scan time: 20.700 The best scores are: opt bits E(85289) NP_066921 (OMIM: 607904,611942,617027) voltage-dep (2353) 16075 1686.0 0 XP_006721026 (OMIM: 607904,611942,617027) PREDICTE (2358) 16015 1679.8 0 NP_001005407 (OMIM: 607904,611942,617027) voltage- (2347) 16005 1678.7 0 XP_005255709 (OMIM: 607904,611942,617027) PREDICTE (2347) 15910 1668.8 0 XP_016879308 (OMIM: 607904,611942,617027) PREDICTE (2345) 14988 1573.0 0 XP_011521026 (OMIM: 607904,611942,617027) PREDICTE (2176) 14751 1548.4 0 XP_006721027 (OMIM: 607904,611942,617027) PREDICTE (2342) 13397 1407.7 0 XP_006721028 (OMIM: 607904,611942,617027) PREDICTE (2336) 13325 1400.2 0 XP_016879310 (OMIM: 607904,611942,617027) PREDICTE (1691) 10944 1152.7 0 XP_016879309 (OMIM: 607904,611942,617027) PREDICTE (1691) 10944 1152.7 0 XP_006721031 (OMIM: 607904,611942,617027) PREDICTE (1612) 10453 1101.7 0 XP_006721030 (OMIM: 607904,611942,617027) PREDICTE (1618) 10453 1101.7 0 XP_011521029 (OMIM: 607904,611942,617027) PREDICTE (1283) 6722 713.9 3.1e-204 NP_938194 (OMIM: 604065,616795) voltage-dependent (2321) 5751 613.2 1.2e-173 NP_938191 (OMIM: 604065,616795) voltage-dependent (2366) 5726 610.7 7.1e-173 NP_938192 (OMIM: 604065,616795) voltage-dependent (2273) 5684 606.3 1.4e-171 NP_001243263 (OMIM: 604065,616795) voltage-depende (2194) 5634 601.1 5.1e-170 NP_001243253 (OMIM: 604065,616795) voltage-depende (2314) 5492 586.3 1.5e-165 NP_938200 (OMIM: 604065,616795) voltage-dependent (2266) 5411 577.9 4.9e-163 NP_001243256 (OMIM: 604065,616795) voltage-depende (2277) 4867 521.4 5.1e-146 NP_001243257 (OMIM: 604065,616795) voltage-depende (2259) 4863 521.0 6.8e-146 NP_938198 (OMIM: 604065,616795) voltage-dependent (2284) 4140 445.8 2.8e-123 NP_001243262 (OMIM: 604065,616795) voltage-depende (2205) 4137 445.5 3.4e-123 NP_061496 (OMIM: 604065,616795) voltage-dependent (2377) 4117 443.5 1.5e-122 NP_001243254 (OMIM: 604065,616795) voltage-depende (2291) 4111 442.8 2.3e-122 NP_938199 (OMIM: 604065,616795) voltage-dependent (2332) 4106 442.3 3.3e-122 NP_001243290 (OMIM: 604065,616795) voltage-depende (2246) 3906 421.5 5.8e-116 NP_001243259 (OMIM: 604065,616795) voltage-depende (2239) 3847 415.4 4e-114 NP_001243289 (OMIM: 604065,616795) voltage-depende (2248) 3811 411.7 5.4e-113 NP_001243258 (OMIM: 604065,616795) voltage-depende (2250) 3751 405.4 4.1e-111 NP_001243260 (OMIM: 604065,616795) voltage-depende (2232) 3723 402.5 3.1e-110 NP_001243288 (OMIM: 604065,616795) voltage-depende (2257) 3694 399.5 2.5e-109 NP_001243255 (OMIM: 604065,616795) voltage-depende (2287) 3693 399.4 2.7e-109 XP_016884525 (OMIM: 608230) PREDICTED: voltage-dep (1605) 3617 391.4 4.9e-107 NP_001003406 (OMIM: 608230) voltage-dependent T-ty (2188) 3617 391.5 6.2e-107 NP_066919 (OMIM: 608230) voltage-dependent T-type (2223) 3617 391.5 6.3e-107 XP_016884526 (OMIM: 608230) PREDICTED: voltage-dep (1593) 3595 389.1 2.4e-106 XP_016884524 (OMIM: 608230) PREDICTED: voltage-dep (1606) 3595 389.1 2.4e-106 NP_938193 (OMIM: 604065,616795) voltage-dependent (2298) 3577 387.3 1.2e-105 NP_938406 (OMIM: 604065,616795) voltage-dependent (2343) 3552 384.8 7.1e-105 NP_938201 (OMIM: 604065,616795) voltage-dependent (2250) 3510 380.4 1.4e-103 NP_938190 (OMIM: 604065,616795) voltage-dependent (2171) 3460 375.2 5e-102 NP_938202 (OMIM: 604065,616795) voltage-dependent (2243) 3237 352.0 4.9e-95 XP_006722224 (OMIM: 604065,616795) PREDICTED: volt (2244) 1966 219.9 2.8e-55 NP_938196 (OMIM: 604065,616795) voltage-dependent (2261) 1966 219.9 2.8e-55 NP_938197 (OMIM: 604065,616795) voltage-dependent (2306) 1956 218.9 5.8e-55 XP_006722223 (OMIM: 604065,616795) PREDICTED: volt (2268) 1937 216.9 2.3e-54 NP_001243261 (OMIM: 604065,616795) voltage-depende (2227) 1577 179.5 4.1e-43 XP_016861142 (OMIM: 604385,615548,615552) PREDICTE (1259) 957 114.9 6.5e-24 XP_011531623 (OMIM: 604385,615548,615552) PREDICTE (1570) 957 115.0 7.7e-24 >>NP_066921 (OMIM: 607904,611942,617027) voltage-depende (2353 aa) initn: 16075 init1: 16075 opt: 16075 Z-score: 9036.2 bits: 1686.0 E(85289): 0 Smith-Waterman score: 16075; 99.9% identity (100.0% similar) in 2353 aa overlap (1-2353:1-2353) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE2 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE2 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE2 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE2 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KE2 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KE2 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASDPADEE ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_066 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEE 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KE2 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KE2 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KE2 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KE2 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_066 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS 2290 2300 2310 2320 2330 2340 2350 pF1KE2 ATPAPGGGADDPV ::::::::::::: NP_066 ATPAPGGGADDPV 2350 >>XP_006721026 (OMIM: 607904,611942,617027) PREDICTED: v (2358 aa) initn: 16023 init1: 10894 opt: 16015 Z-score: 9002.5 bits: 1679.8 E(85289): 0 Smith-Waterman score: 16015; 99.5% identity (99.7% similar) in 2358 aa overlap (1-2353:1-2358) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRS-TFPSP----EAQRRPYYADYSPTRRSIHSLCT ::::::::::::::::::::::::::: ..: ::::::::::::::::::::::: XP_006 CRQHQEAEEARRREEKRLRRLERRRRSKALPVAVAVAEAQRRPYYADYSPTRRSIHSLCT 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE2 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KE2 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KE2 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KE2 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KE2 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KE2 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KE2 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KE2 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASD :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: XP_006 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASD 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 2140 2150 pF1KE2 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR 2110 2120 2130 2140 2150 2160 2160 2170 2180 2190 2200 2210 pF1KE2 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT 2170 2180 2190 2200 2210 2220 2220 2230 2240 2250 2260 2270 pF1KE2 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV 2230 2240 2250 2260 2270 2280 2280 2290 2300 2310 2320 2330 pF1KE2 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK 2290 2300 2310 2320 2330 2340 2340 2350 pF1KE2 PGSPSATPAPGGGADDPV :::::::::::::::::: XP_006 PGSPSATPAPGGGADDPV 2350 >>NP_001005407 (OMIM: 607904,611942,617027) voltage-depe (2347 aa) initn: 10891 init1: 10891 opt: 16005 Z-score: 8997.0 bits: 1678.7 E(85289): 0 Smith-Waterman score: 16005; 99.6% identity (99.7% similar) in 2353 aa overlap (1-2353:1-2347) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD :::::::::::::::::::::::::: .::::::::::::::::::::::::::: NP_001 CRQHQEAEEARRREEKRLRRLERRRR------KAQRRPYYADYSPTRRSIHSLCTSHYLD 1570 1580 1590 1600 1610 1630 1640 1650 1660 1670 1680 pF1KE2 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR 1620 1630 1640 1650 1660 1670 1690 1700 1710 1720 1730 1740 pF1KE2 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD 1680 1690 1700 1710 1720 1730 1750 1760 1770 1780 1790 1800 pF1KE2 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT 1740 1750 1760 1770 1780 1790 1810 1820 1830 1840 1850 1860 pF1KE2 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM 1800 1810 1820 1830 1840 1850 1870 1880 1890 1900 1910 1920 pF1KE2 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS 1860 1870 1880 1890 1900 1910 1930 1940 1950 1960 1970 1980 pF1KE2 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ 1920 1930 1940 1950 1960 1970 1990 2000 2010 2020 2030 2040 pF1KE2 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP 1980 1990 2000 2010 2020 2030 2050 2060 2070 2080 2090 2100 pF1KE2 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASDPADEE ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEE 2040 2050 2060 2070 2080 2090 2110 2120 2130 2140 2150 2160 pF1KE2 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL 2100 2110 2120 2130 2140 2150 2170 2180 2190 2200 2210 2220 pF1KE2 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT 2160 2170 2180 2190 2200 2210 2230 2240 2250 2260 2270 2280 pF1KE2 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP 2220 2230 2240 2250 2260 2270 2290 2300 2310 2320 2330 2340 pF1KE2 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS 2280 2290 2300 2310 2320 2330 2350 pF1KE2 ATPAPGGGADDPV ::::::::::::: NP_001 ATPAPGGGADDPV 2340 >>XP_005255709 (OMIM: 607904,611942,617027) PREDICTED: v (2347 aa) initn: 13528 init1: 10894 opt: 15910 Z-score: 8943.6 bits: 1668.8 E(85289): 0 Smith-Waterman score: 15910; 99.1% identity (99.2% similar) in 2358 aa overlap (1-2353:1-2347) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRS-TFPSP----EAQRRPYYADYSPTRRSIHSLCT ::::::::::::::::::::::::::: ..: ::::::::::::::::::::::: XP_005 CRQHQEAEEARRREEKRLRRLERRRRSKALPVAVAVAEAQRRPYYADYSPTRRSIHSLCT 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE2 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KE2 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KE2 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KE2 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KE2 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KE2 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES ::::::::::::::::::::::::::::::::::::::::::::::: :: XP_005 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPL-----------ES 1930 1940 1950 1960 1980 1990 2000 2010 2020 2030 pF1KE2 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL 1970 1980 1990 2000 2010 2020 2040 2050 2060 2070 2080 2090 pF1KE2 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASD :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: XP_005 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASD 2030 2040 2050 2060 2070 2080 2100 2110 2120 2130 2140 2150 pF1KE2 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR 2090 2100 2110 2120 2130 2140 2160 2170 2180 2190 2200 2210 pF1KE2 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT 2150 2160 2170 2180 2190 2200 2220 2230 2240 2250 2260 2270 pF1KE2 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV 2210 2220 2230 2240 2250 2260 2280 2290 2300 2310 2320 2330 pF1KE2 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK 2270 2280 2290 2300 2310 2320 2340 2350 pF1KE2 PGSPSATPAPGGGADDPV :::::::::::::::::: XP_005 PGSPSATPAPGGGADDPV 2330 2340 >>XP_016879308 (OMIM: 607904,611942,617027) PREDICTED: v (2345 aa) initn: 14986 init1: 9857 opt: 14988 Z-score: 8425.9 bits: 1573.0 E(85289): 0 Smith-Waterman score: 15895; 99.0% identity (99.2% similar) in 2358 aa overlap (1-2353:1-2345) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV ::::::::::::::::: :::::::::::::::::::::::::::::: XP_016 RPCEDVECGSERCNILE-------------MVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 170 180 190 200 210 220 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 290 300 310 320 330 340 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 350 360 370 380 390 400 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 410 420 430 440 450 460 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 470 480 490 500 510 520 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 530 540 550 560 570 580 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 590 600 610 620 630 640 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 650 660 670 680 690 700 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 710 720 730 740 750 760 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 770 780 790 800 810 820 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 830 840 850 860 870 880 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 890 900 910 920 930 940 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 950 960 970 980 990 1000 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1010 1020 1030 1040 1050 1060 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1070 1080 1090 1100 1110 1120 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1130 1140 1150 1160 1170 1180 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1190 1200 1210 1220 1230 1240 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1250 1260 1270 1280 1290 1300 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1310 1320 1330 1340 1350 1360 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1370 1380 1390 1400 1410 1420 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1430 1440 1450 1460 1470 1480 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1490 1500 1510 1520 1530 1540 1570 1580 1590 1600 1610 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRS-TFPSP----EAQRRPYYADYSPTRRSIHSLCT ::::::::::::::::::::::::::: ..: ::::::::::::::::::::::: XP_016 CRQHQEAEEARRREEKRLRRLERRRRSKALPVAVAVAEAQRRPYYADYSPTRRSIHSLCT 1550 1560 1570 1580 1590 1600 1620 1630 1640 1650 1660 1670 pF1KE2 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHYLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRR 1610 1620 1630 1640 1650 1660 1680 1690 1700 1710 1720 1730 pF1KE2 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFKDRWNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGM 1670 1680 1690 1700 1710 1720 1740 1750 1760 1770 1780 1790 pF1KE2 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFG 1730 1740 1750 1760 1770 1780 1800 1810 1820 1830 1840 1850 pF1KE2 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAFLTLFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVV 1790 1800 1810 1820 1830 1840 1860 1870 1880 1890 1900 1910 pF1KE2 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAVLMKHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLV 1850 1860 1870 1880 1890 1900 1920 1930 1940 1950 1960 1970 pF1KE2 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ARKVSVSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAES 1910 1920 1930 1940 1950 1960 1980 1990 2000 2010 2020 2030 pF1KE2 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CASLQIPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTL 1970 1980 1990 2000 2010 2020 2040 2050 2060 2070 2080 2090 pF1KE2 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASD :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: XP_016 DPAEPGEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASD 2030 2040 2050 2060 2070 2080 2100 2110 2120 2130 2140 2150 pF1KE2 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PADEEVSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWR 2090 2100 2110 2120 2130 2140 2160 2170 2180 2190 2200 2210 pF1KE2 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSAELGSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTT 2150 2160 2170 2180 2190 2200 2220 2230 2240 2250 2260 2270 pF1KE2 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRRRTPSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGV 2210 2220 2230 2240 2250 2260 2280 2290 2300 2310 2320 2330 pF1KE2 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PSGDPFLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEK 2270 2280 2290 2300 2310 2320 2340 2350 pF1KE2 PGSPSATPAPGGGADDPV :::::::::::::::::: XP_016 PGSPSATPAPGGGADDPV 2330 2340 >>XP_011521026 (OMIM: 607904,611942,617027) PREDICTED: v (2176 aa) initn: 14759 init1: 9630 opt: 14751 Z-score: 8293.2 bits: 1548.4 E(85289): 0 Smith-Waterman score: 14751; 99.5% identity (99.7% similar) in 2176 aa overlap (183-2353:1-2176) 160 170 180 190 200 210 pF1KE2 IKMVALGLFGQKCYLGDTWNRLDFFIVVAGMMEYSLDGHNVSLSAIRTVRVLRPLRAINR :::::::::::::::::::::::::::::: XP_011 MMEYSLDGHNVSLSAIRTVRVLRPLRAINR 10 20 30 220 230 240 250 260 270 pF1KE2 VPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNL 40 50 60 70 80 90 280 290 300 310 320 330 pF1KE2 TFLRPYYQTEEGEENPFICSSRRDNGMQKCSHIPGRRELRMPCTLGWEAYTQPQAEGVGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFLRPYYQTEEGEENPFICSSRRDNGMQKCSHIPGRRELRMPCTLGWEAYTQPQAEGVGA 100 110 120 130 140 150 340 350 360 370 380 390 pF1KE2 ARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ARNACINWNQYYNVCRSGDSNPHNGAINFDNIGYAWIAIFQVITLEGWVDIMYYVMDAHS 160 170 180 190 200 210 400 410 420 430 440 450 pF1KE2 FYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRARHLSNDSTLASFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRARHLSNDSTLASFSE 220 230 240 250 260 270 460 470 480 490 500 510 pF1KE2 PGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSCYEELLKYVGHIFRKVKRRSLRLYARWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTA 280 290 300 310 320 330 520 530 540 550 560 570 pF1KE2 SVHHLVYHHHHHHHHHYHFSHGSPRRPGPEPGACDTRLVRAGAPPSPPSPGRGPPDAESV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVHHLVYHHHHHHHHHYHFSHGSPRRPGPEPGACDTRLVRAGAPPSPPSPGRGPPDAESV 340 350 360 370 380 390 580 590 600 610 620 630 pF1KE2 HSIYHADCHIEGPQERARVAHAAATAAASLRLATGLGTMNYPTILPSGVGSGKGSTSPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSIYHADCHIEGPQERARVAHAAATAAASLRLATGLGTMNYPTILPSGVGSGKGSTSPGP 400 410 420 430 440 450 640 650 660 670 680 690 pF1KE2 KGKWAGGPPGTGGHGPLSLNSPDPYEKIPHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGT :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::: XP_011 KGKWAGGPPGTGGHGPLSLNSPDPYEKIPHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGT 460 470 480 490 500 510 700 710 720 730 740 750 pF1KE2 LTCELKSCPYCTRALEDPEGELSGSESGDSDGRGVYEFTQDVRHGDRWDPTRPPRATDTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTCELKSCPYCTRALEDPEGELSGSESGDSDGRGVYEFTQDVRHGDRWDPTRPPRATDTP 520 530 540 550 560 570 760 770 780 790 800 810 pF1KE2 GPGPGSPQRRAQQRAAPGEPGWMGRLWVTFSGKLRRIVDSKYFSRGIMMAILVNTLSMGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPGPGSPQRRAQQRAAPGEPGWMGRLWVTFSGKLRRIVDSKYFSRGIMMAILVNTLSMGV 580 590 600 610 620 630 820 830 840 850 860 870 pF1KE2 EYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EYHEQPEELTNALEISNIVFTSMFALEMLLKLLACGPLGYIRNPYNIFDGIIVVISVWEI 640 650 660 670 680 690 880 890 900 910 920 930 pF1KE2 VGQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGQADGGLSVLRTFRLLRVLKLVRFLPALRRQLVVLVKTMDNVATFCTLLMLFIFIFSIL 700 710 720 730 740 750 940 950 960 970 980 990 pF1KE2 GMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMHLFGCKFSLKTDTGDTVPDRKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSSWAA 760 770 780 790 800 810 1000 1010 1020 1030 1040 1050 pF1KE2 LYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSVHFEEDFHKLRELQTTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYFVALMTFGNYVLFNLLVAILVEGFQAEGDANRSDTDEDKTSVHFEEDFHKLRELQTTE 820 830 840 850 860 870 1060 1070 1080 1090 1100 1110 pF1KE2 LKMCSLAVTPNGHLEGRGSLSPPLIMCTAATPMPTPKSSPFLDAAPSLPDSRRGSSSSGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKMCSLAVTPNGHLEGRGSLSPPLIMCTAATPMPTPKSSPFLDAAPSLPDSRRGSSSSGD 880 890 900 910 920 930 1120 1130 1140 1150 1160 1170 pF1KE2 PPLGDQKPPASLRSSPCAPWGPSGAWSSRRSSWSSLGRAPSLKRRGQCGERESLLSGEGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLGDQKPPASLRSSPCAPWGPSGAWSSRRSSWSSLGRAPSLKRRGQCGERESLLSGEGK 940 950 960 970 980 990 1180 1190 1200 1210 1220 1230 pF1KE2 GSTDDEAEDGRAAPGPRATPLRRAESLDPRPLRPAALPPTKCRDRDGQVVALPSDFFLRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSTDDEAEDGRAAPGPRATPLRRAESLDPRPLRPAALPPTKCRDRDGQVVALPSDFFLRI 1000 1010 1020 1030 1040 1050 1240 1250 1260 1270 1280 1290 pF1KE2 DSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQNRFRVSCQKVIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSHREDAAELDDDSEDSCCLRLHKVLEPYKPQWCRSREAWALYLFSPQNRFRVSCQKVIT 1060 1070 1080 1090 1100 1110 1300 1310 1320 1330 1340 1350 pF1KE2 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKMFDHVVLVFIFLNCVTIALERPDIDPGSTERVFLSVSNYIFTAIFVAEMMVKVVALGL 1120 1130 1140 1150 1160 1170 1360 1370 1380 1390 1400 1410 pF1KE2 LSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSGEHAYLQSSWNLLDGLLVLVSLVDIVVAMASAGGAKILGVLRVLRLLRTLRPLRVISR 1180 1190 1200 1210 1220 1230 1420 1430 1440 1450 1460 1470 pF1KE2 APGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APGLKLVVETLISSLRPIGNIVLICCAFFIIFGILGVQLFKGKFYYCEGPDTRNISTKAQ 1240 1250 1260 1270 1280 1290 1480 1490 1500 1510 1520 1530 pF1KE2 CRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CRAAHYRWVRRKYNFDNLGQALMSLFVLSSKDGWVNIMYDGLDAVGVDQQPVQNHNPWML 1300 1310 1320 1330 1340 1350 1540 1550 1560 1570 1580 1590 pF1KE2 LYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRS-TFPS ::::::::::::::::::::::::::::::::::::::::::::::::::::::: ..: XP_011 LYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRREEKRLRRLERRRRSKALPV 1360 1370 1380 1390 1400 1410 1600 1610 1620 1630 1640 pF1KE2 P----EAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVAVAEAQRRPYYADYSPTRRSIHSLCTSHYLDLFITFIICVNVITMSMEHYNQPKSLDE 1420 1430 1440 1450 1460 1470 1650 1660 1670 1680 1690 1700 pF1KE2 ALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDRWNQLDLAIVLLSLMGITLEEIEMSAAL 1480 1490 1500 1510 1520 1530 1710 1720 1730 1740 1750 1760 pF1KE2 PINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PINPTIIRIMRVLRIARVLKLLKMATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALG 1540 1550 1560 1570 1580 1590 1770 1780 1790 1800 1810 1820 pF1KE2 VELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSREDKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VELFGRLECSEDNPCEGLSRHATFSNFGMAFLTLFRVSTGDNWNGIMKDTLRECSREDKH 1600 1610 1620 1630 1640 1650 1830 1840 1850 1860 1870 1880 pF1KE2 CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLMKHLEESNKEAREDAELDAEIELEMAQG 1660 1670 1680 1690 1700 1710 1890 1900 1910 1920 1930 1940 pF1KE2 PGSARRVDADRPPLPQESPGARDAPNLVARKVSVSRMLSLPNDSYMFRPVVPASAPHPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGSARRVDADRPPLPQESPGARDAPNLVARKVSVSRMLSLPNDSYMFRPVVPASAPHPRP 1720 1730 1740 1750 1760 1770 1950 1960 1970 1980 1990 2000 pF1KE2 LQEVEMETYGAGTPLGSVASVHSPPAESCASLQIPLAVSSPARSGEPLHALSPRGTARSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEVEMETYGAGTPLGSVASVHSPPAESCASLQIPLAVSSPARSGEPLHALSPRGTARSP 1780 1790 1800 1810 1820 1830 2010 2020 2030 2040 2050 2060 pF1KE2 SLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKTPVRPVTQGGSLQSPPRSPRPASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEPGEKTPVRPVTQGGSLQSPPRSPRPASV 1840 1850 1860 1870 1880 1890 2070 2080 2090 2100 2110 2120 pF1KE2 RTRKHTFGQHCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAG :::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTRKHTFGQRCVSSRPAAPGGEEAEASDPADEEVSHITSSACPWQPTAEPHGPEASPVAG 1900 1910 1920 1930 1940 1950 2130 2140 2150 2160 2170 2180 pF1KE2 GERDLRRLYSVDAQGFLDKPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGARRKKKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GERDLRRLYSVDAQGFLDKPGRADEQWRPSAELGSGEPGEAKAWGPEAEPALGARRKKKM 1960 1970 1980 1990 2000 2010 2190 2200 2210 2220 2230 2240 pF1KE2 SPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAGGDPAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPPCISVEPPAEDEGSARPSAAEGGSTTLRRRTPSCEATPHRDSLEPTEGSGAGGDPAAK 2020 2030 2040 2050 2060 2070 2250 2260 2270 2280 2290 2300 pF1KE2 GERWGQASCRAEHLTVPSFAFEPLDLGVPSGDPFLDGSHSVTPESRASSSGAIVPLEPPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GERWGQASCRAEHLTVPSFAFEPLDLGVPSGDPFLDGSHSVTPESRASSSGAIVPLEPPE 2080 2090 2100 2110 2120 2130 2310 2320 2330 2340 2350 pF1KE2 SEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPSATPAPGGGADDPV :::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPSATPAPGGGADDPV 2140 2150 2160 2170 >>XP_006721027 (OMIM: 607904,611942,617027) PREDICTED: v (2342 aa) initn: 13385 init1: 13385 opt: 13397 Z-score: 7532.4 bits: 1407.7 E(85289): 0 Smith-Waterman score: 15970; 99.4% identity (99.5% similar) in 2353 aa overlap (1-2353:1-2342) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE2 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE2 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE2 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE2 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ :::::::::::::::::::::::::::::::::::::::::: ::::::: XP_006 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPL-----------ESCASLQ 1930 1940 1950 1960 1990 2000 2010 2020 2030 2040 pF1KE2 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP 1970 1980 1990 2000 2010 2020 2050 2060 2070 2080 2090 2100 pF1KE2 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASDPADEE ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_006 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEE 2030 2040 2050 2060 2070 2080 2110 2120 2130 2140 2150 2160 pF1KE2 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL 2090 2100 2110 2120 2130 2140 2170 2180 2190 2200 2210 2220 pF1KE2 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT 2150 2160 2170 2180 2190 2200 2230 2240 2250 2260 2270 2280 pF1KE2 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP 2210 2220 2230 2240 2250 2260 2290 2300 2310 2320 2330 2340 pF1KE2 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS 2270 2280 2290 2300 2310 2320 2350 pF1KE2 ATPAPGGGADDPV ::::::::::::: XP_006 ATPAPGGGADDPV 2330 2340 >>XP_006721028 (OMIM: 607904,611942,617027) PREDICTED: v (2336 aa) initn: 13525 init1: 10891 opt: 13325 Z-score: 7492.0 bits: 1400.2 E(85289): 0 Smith-Waterman score: 15900; 99.2% identity (99.3% similar) in 2353 aa overlap (1-2353:1-2336) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQRRPYYADYSPTRRSIHSLCTSHYLD :::::::::::::::::::::::::: .::::::::::::::::::::::::::: XP_006 CRQHQEAEEARRREEKRLRRLERRRR------KAQRRPYYADYSPTRRSIHSLCTSHYLD 1570 1580 1590 1600 1610 1630 1640 1650 1660 1670 1680 pF1KE2 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFFKDR 1620 1630 1640 1650 1660 1670 1690 1700 1710 1720 1730 1740 pF1KE2 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WNQLDLAIVLLSLMGITLEEIEMSAALPINPTIIRIMRVLRIARVLKLLKMATGMRALLD 1680 1690 1700 1710 1720 1730 1750 1760 1770 1780 1790 1800 pF1KE2 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVVQALPQVGNLGLLFMLLFFIYAALGVELFGRLECSEDNPCEGLSRHATFSNFGMAFLT 1740 1750 1760 1770 1780 1790 1810 1820 1830 1840 1850 1860 pF1KE2 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LFRVSTGDNWNGIMKDTLRECSREDKHCLSYLPALSPVYFVTFVLVAQFVLVNVVVAVLM 1800 1810 1820 1830 1840 1850 1870 1880 1890 1900 1910 1920 pF1KE2 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KHLEESNKEAREDAELDAEIELEMAQGPGSARRVDADRPPLPQESPGARDAPNLVARKVS 1860 1870 1880 1890 1900 1910 1930 1940 1950 1960 1970 1980 pF1KE2 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPLGSVASVHSPPAESCASLQ :::::::::::::::::::::::::::::::::::::::::: ::::::: XP_006 VSRMLSLPNDSYMFRPVVPASAPHPRPLQEVEMETYGAGTPL-----------ESCASLQ 1920 1930 1940 1950 1960 1990 2000 2010 2020 2030 2040 pF1KE2 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IPLAVSSPARSGEPLHALSPRGTARSPSLSRLLCRQEAVHTDSLEGKIDSPRDTLDPAEP 1970 1980 1990 2000 2010 2020 2050 2060 2070 2080 2090 2100 pF1KE2 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQHCVSSRPAAPGGEEAEASDPADEE ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: XP_006 GEKTPVRPVTQGGSLQSPPRSPRPASVRTRKHTFGQRCVSSRPAAPGGEEAEASDPADEE 2030 2040 2050 2060 2070 2080 2110 2120 2130 2140 2150 2160 pF1KE2 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VSHITSSACPWQPTAEPHGPEASPVAGGERDLRRLYSVDAQGFLDKPGRADEQWRPSAEL 2090 2100 2110 2120 2130 2140 2170 2180 2190 2200 2210 2220 pF1KE2 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GSGEPGEAKAWGPEAEPALGARRKKKMSPPCISVEPPAEDEGSARPSAAEGGSTTLRRRT 2150 2160 2170 2180 2190 2200 2230 2240 2250 2260 2270 2280 pF1KE2 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PSCEATPHRDSLEPTEGSGAGGDPAAKGERWGQASCRAEHLTVPSFAFEPLDLGVPSGDP 2210 2220 2230 2240 2250 2260 2290 2300 2310 2320 2330 2340 pF1KE2 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLDGSHSVTPESRASSSGAIVPLEPPESEPPMPVGDPPEKRRGLYLTVPQCPLEKPGSPS 2270 2280 2290 2300 2310 2320 2350 pF1KE2 ATPAPGGGADDPV ::::::::::::: XP_006 ATPAPGGGADDPV 2330 >>XP_016879310 (OMIM: 607904,611942,617027) PREDICTED: v (1691 aa) initn: 10932 init1: 10932 opt: 10944 Z-score: 6156.9 bits: 1152.7 E(85289): 0 Smith-Waterman score: 10944; 99.0% identity (99.4% similar) in 1612 aa overlap (1-1609:1-1612) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQ---RRPYYADYSPTRRSIHSLCTSH :::::::::::::::::::::::::::::::: .. ..: :.::: XP_016 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPGGEWSLQEPGAPGGPPARRSWPPSPQRP 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE2 YLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFF XP_016 SAGPTMPTTRPRAAPFTRCAPATISTSSSPSSSVSTSSPCPWSTITNPSRWTRPSSTATT 1630 1640 1650 1660 1670 1680 >>XP_016879309 (OMIM: 607904,611942,617027) PREDICTED: v (1691 aa) initn: 10932 init1: 10932 opt: 10944 Z-score: 6156.9 bits: 1152.7 E(85289): 0 Smith-Waterman score: 10944; 99.0% identity (99.4% similar) in 1612 aa overlap (1-1609:1-1612) 10 20 30 40 50 60 pF1KE2 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MTEGARAADEVRVPLGAPPPGPAALVGASPESPGAPGREAERGSELGVSPSESPAAERGA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELGADEEQRVPYPALAATVFFCLGQTTRPRSWCLRLVCNPWFEHVSMLVIMLNCVTLGMF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RPCEDVECGSERCNILEAFDAFIFAFFAVEMVIKMVALGLFGQKCYLGDTWNRLDFFIVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGMMEYSLDGHNVSLSAIRTVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFIFGIVGVQLWAGLLRNRCFLDSAFVRNNNLTFLRPYYQTEEGEENPFICSSRRDNGMQ 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KCSHIPGRRELRMPCTLGWEAYTQPQAEGVGAARNACINWNQYYNVCRSGDSNPHNGAIN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDNIGYAWIAIFQVITLEGWVDIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIAT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QFSETKQRESQLMREQRARHLSNDSTLASFSEPGSCYEELLKYVGHIFRKVKRRSLRLYA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RWQSRWRKKVDPSAVQGQGPGHRQRRAGRHTASVHHLVYHHHHHHHHHYHFSHGSPRRPG 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEPGACDTRLVRAGAPPSPPSPGRGPPDAESVHSIYHADCHIEGPQERARVAHAAATAAA 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SLRLATGLGTMNYPTILPSGVGSGKGSTSPGPKGKWAGGPPGTGGHGPLSLNSPDPYEKI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 PHVAGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHVVGEHGLGQAPGHLSGLSVPCPLPSPPAGTLTCELKSCPYCTRALEDPEGELSGSESG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSDGRGVYEFTQDVRHGDRWDPTRPPRATDTPGPGPGSPQRRAQQRAAPGEPGWMGRLWV 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TFSGKLRRIVDSKYFSRGIMMAILVNTLSMGVEYHEQPEELTNALEISNIVFTSMFALEM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKLLACGPLGYIRNPYNIFDGIIVVISVWEIVGQADGGLSVLRTFRLLRVLKLVRFLPA 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRRQLVVLVKTMDNVATFCTLLMLFIFIFSILGMHLFGCKFSLKTDTGDTVPDRKNFDSL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWAIVTVFQILTQEDWNVVLYNGMASTSSWAALYFVALMTFGNYVLFNLLVAILVEGFQA 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGDANRSDTDEDKTSVHFEEDFHKLRELQTTELKMCSLAVTPNGHLEGRGSLSPPLIMCT 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AATPMPTPKSSPFLDAAPSLPDSRRGSSSSGDPPLGDQKPPASLRSSPCAPWGPSGAWSS 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRSSWSSLGRAPSLKRRGQCGERESLLSGEGKGSTDDEAEDGRAAPGPRATPLRRAESLD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PRPLRPAALPPTKCRDRDGQVVALPSDFFLRIDSHREDAAELDDDSEDSCCLRLHKVLEP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKPQWCRSREAWALYLFSPQNRFRVSCQKVITHKMFDHVVLVFIFLNCVTIALERPDIDP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSTERVFLSVSNYIFTAIFVAEMMVKVVALGLLSGEHAYLQSSWNLLDGLLVLVSLVDIV 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAMASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLISSLRPIGNIVLICCAF 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIIFGILGVQLFKGKFYYCEGPDTRNISTKAQCRAAHYRWVRRKYNFDNLGQALMSLFVL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSKDGWVNIMYDGLDAVGVDQQPVQNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 pF1KE2 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPEAQ---RRPYYADYSPTRRSIHSLCTSH :::::::::::::::::::::::::::::::: .. ..: :.::: XP_016 CRQHQEAEEARRREEKRLRRLERRRRSTFPSPGGEWSLQEPGAPGGPPARRSWPPSPQRP 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE2 YLDLFITFIICVNVITMSMEHYNQPKSLDEALKYCNYVFTIVFVFEAALKLVAFGFRRFF XP_016 SAGPTMPTTRPRAAPFTRCAPATISTSSSPSSSVSTSSPCPWSTITNPSRWTRPSSTATT 1630 1640 1650 1660 1670 1680 2353 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 21:00:09 2016 done: Mon Nov 7 21:00:12 2016 Total Scan time: 20.700 Total Display time: 1.550 Function used was FASTA [36.3.4 Apr, 2011]