Result of FASTA (ccds) for
pF1KE2493
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2493, 263 aa
1>>>pF1KE2493 263 - 263 aa - 263 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6464+/-0.000813; mu= 16.2728+/- 0.049
mean_var=147.9923+/-28.160, 0's: 0 Z-trim(113.6): 42 B-trim: 3 in 1/50
Lambda= 0.105428
statistics sampled from 14199 (14237) to 14199 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.437), width: 16
Scan time: 2.190
The best scores are: opt bits E(32554)
CCDS41304.1 RSPO1 gene_id:284654|Hs108|chr1 ( 263) 1898 299.5 1.5e-81
CCDS55591.1 RSPO1 gene_id:284654|Hs108|chr1 ( 236) 1701 269.5 1.5e-72
CCDS55590.1 RSPO1 gene_id:284654|Hs108|chr1 ( 200) 1066 172.8 1.6e-43
CCDS5135.1 RSPO3 gene_id:84870|Hs108|chr6 ( 272) 885 145.5 3.8e-35
CCDS6307.1 RSPO2 gene_id:340419|Hs108|chr8 ( 243) 744 124.0 1e-28
CCDS42846.1 RSPO4 gene_id:343637|Hs108|chr20 ( 234) 652 109.9 1.6e-24
CCDS83314.1 RSPO2 gene_id:340419|Hs108|chr8 ( 176) 610 103.4 1.1e-22
CCDS64953.1 RSPO2 gene_id:340419|Hs108|chr8 ( 179) 475 82.9 1.7e-16
CCDS42845.1 RSPO4 gene_id:343637|Hs108|chr20 ( 172) 460 80.6 8.3e-16
>>CCDS41304.1 RSPO1 gene_id:284654|Hs108|chr1 (263 aa)
initn: 1898 init1: 1898 opt: 1898 Z-score: 1577.4 bits: 299.5 E(32554): 1.5e-81
Smith-Waterman score: 1898; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263)
10 20 30 40 50 60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
190 200 210 220 230 240
250 260
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
:::::::::::::::::::::::
CCDS41 RRKGQQQQQQQGTVGPLTSAGPA
250 260
>>CCDS55591.1 RSPO1 gene_id:284654|Hs108|chr1 (236 aa)
initn: 1701 init1: 1701 opt: 1701 Z-score: 1416.0 bits: 269.5 E(32554): 1.5e-72
Smith-Waterman score: 1701; 99.6% identity (100.0% similar) in 233 aa overlap (31-263:4-236)
10 20 30 40 50 60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
:.::::::::::::::::::::::::::::
CCDS55 MIFRVSAEGSQACAKGCELCSEVNGCLKCSPKL
10 20 30
70 80 90 100 110 120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
160 170 180 190 200 210
250 260
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
:::::::::::::::::::::::
CCDS55 RRKGQQQQQQQGTVGPLTSAGPA
220 230
>>CCDS55590.1 RSPO1 gene_id:284654|Hs108|chr1 (200 aa)
initn: 1109 init1: 1066 opt: 1066 Z-score: 894.7 bits: 172.8 E(32554): 1.6e-43
Smith-Waterman score: 1288; 76.0% identity (76.0% similar) in 263 aa overlap (1-263:1-200)
10 20 30 40 50 60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
:::::::::::::::::::::::::
CCDS55 HKGRCYPACPEGSSAANGTMECSSP-----------------------------------
130 140
190 200 210 220 230 240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
::::::::::::::::::::::::::::::::
CCDS55 ----------------------------GQKRRKGGQGRRENANRNLARKESKEAGAGSR
150 160 170
250 260
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
:::::::::::::::::::::::
CCDS55 RRKGQQQQQQQGTVGPLTSAGPA
180 190 200
>>CCDS5135.1 RSPO3 gene_id:84870|Hs108|chr6 (272 aa)
initn: 881 init1: 508 opt: 885 Z-score: 744.5 bits: 145.5 E(32554): 3.8e-35
Smith-Waterman score: 885; 46.0% identity (72.2% similar) in 252 aa overlap (10-251:11-257)
10 20 30 40 50
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPK
..:.. . :. . .:.::::. . ::.: :: ::. ::::.:.:.
CCDS51 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 LFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLY
::. ::: ..:.:::: ::: ::. .: ::.::: ::: . :..::..::::::: :.:
CCDS51 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFY
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 LHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRV
:: :.: :::: : : :::: : ..::.:::.::.::.:: . :::.::.: :.:..
CCDS51 LHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 LHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGS
.. : . : :.:::.:::.: : .:.. .:: . .:.. :.. ::::: :
CCDS51 IQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKG----ESKEAIPDS
180 190 200 210 220 230
240 250 260
pF1KE2 R----------RRKGQQQQQQQGTVGPLTSAGPA
. .:...:::...
CCDS51 KSLESSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH
240 250 260 270
>>CCDS6307.1 RSPO2 gene_id:340419|Hs108|chr8 (243 aa)
initn: 723 init1: 485 opt: 744 Z-score: 629.2 bits: 124.0 E(32554): 1e-28
Smith-Waterman score: 744; 41.5% identity (67.5% similar) in 234 aa overlap (1-234:1-231)
10 20 30 40 50 60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
:.. : ::.. .: . .:..: : .. : ::: ::. ::: .:. ::
CCDS63 MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPIC-KGCLSCSKDNGCSRCQQKL
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
:..:.:. .:: : :: ::: ::. : ::::.: .:.::.:..:::..:::::: :.::
CCDS63 FFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
:.:::. ::.: . . :::: ::...:: :: ::.... :::. : : :::...
CCDS63 HRGRCFDECPDGFAPLEETMECVE--GCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR
. :: : : :.::: . :: :.. :. . : .. .:.: .. ...
CCDS63 KKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLA
180 190 200 210 220 230
250 260
pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA
CCDS63 TDRANQ
240
>>CCDS42846.1 RSPO4 gene_id:343637|Hs108|chr20 (234 aa)
initn: 554 init1: 245 opt: 652 Z-score: 553.7 bits: 109.9 E(32554): 1.6e-24
Smith-Waterman score: 652; 38.6% identity (68.2% similar) in 233 aa overlap (1-230:1-222)
10 20 30 40 50 60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
:: ::.. :: . . .: :...... . :. :: .::: ::: :. .:
CCDS42 MRAPLCLLLLVAHAVDMLALNR-----RKKQVGTGLGGNCT-GCIICSEENGCSTCQQRL
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
:....:. ::: : :: .:::::: :. ..:.: :: ::.:::..:: .::. .::
CCDS42 FLFIRREGIRQYGKCLHDCPPGYFGIRGQEVNRCKKCGAT-CESCFSQDFCIRCKRQFYL
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL
.::.: :.:: :. : ..: ::.. .::.. :. :.::... . :: : : :.:..
CCDS42 YKGKCLPTCPPGTLAHQNTRECQG--ECELGPWGGWSPCTHNGKTCGSAWGLESRVREAG
120 130 140 150 160 170
190 200 210 220 230
pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQK---RRKGGQGRRENANRNLARKESKEAGA
.: . :.:. .:.:.: ..: ::: :.. ..:: . :: .:.: :.
CCDS42 RAGHEEAATCQVLSESRKCPIQR-PCP-GERSPGQKKGRKDRRPRKDRKLDRRLDVRPRQ
180 190 200 210 220
240 250 260
pF1KE2 GSRRRKGQQQQQQQGTVGPLTSAGPA
CCDS42 PGLQP
230
>>CCDS83314.1 RSPO2 gene_id:340419|Hs108|chr8 (176 aa)
initn: 615 init1: 377 opt: 610 Z-score: 520.5 bits: 103.4 E(32554): 1.1e-22
Smith-Waterman score: 610; 44.6% identity (70.5% similar) in 166 aa overlap (69-234:1-164)
40 50 60 70 80 90
pF1KE2 ACAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCK
.:: : :: ::: ::. : ::::.: .:.
CCDS83 MRQYGECLHSCPSGYYGHRAPDMNRCARCR
10 20 30
100 110 120 130 140 150
pF1KE2 IEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGP
::.:..:::..:::::: :.:::.:::. ::.: . . :::: ::...:: ::
CCDS83 IENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETMECVEG--CEVGHWSEWGT
40 50 60 70 80
160 170 180 190 200 210
pF1KE2 CSKKQQLCGFRRGSEERTRRVLHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQG
::.... :::. : : :::.... :: : : :.::: . :: :.. :. .
CCDS83 CSRNNRTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEK
90 100 110 120 130 140
220 230 240 250 260
pF1KE2 RRENANRNLARKESKEAGAGSRRRKGQQQQQQQGTVGPLTSAGPA
: .. .:.: .. ...
CCDS83 RNKKKKRKLIERAQEQHSVFLATDRANQ
150 160 170
>>CCDS64953.1 RSPO2 gene_id:340419|Hs108|chr8 (179 aa)
initn: 491 init1: 253 opt: 475 Z-score: 409.5 bits: 82.9 E(32554): 1.7e-16
Smith-Waterman score: 475; 42.0% identity (71.0% similar) in 138 aa overlap (97-234:33-167)
70 80 90 100 110 120
pF1KE2 NDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCY
:.::.:..:::..:::::: :.:::.:::.
CCDS64 FRLFSFALIILNCMDYSHCQGNRWRRSKRGCRIENCDSCFSKDFCTKCKVGFYLHRGRCF
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE2 PACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVLHAPVGD
::.: . . :::: . ::...:: :: ::.... :::. : : :::.... :: :
CCDS64 DECPDGFAPLEETMECVG---CEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPVKD
70 80 90 100 110
190 200 210 220 230 240
pF1KE2 HAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSRRRKGQQ
: :.::: . :: :.. :. . : .. .:.: .. ...
CCDS64 TILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLATDRANQ
120 130 140 150 160 170
250 260
pF1KE2 QQQQQGTVGPLTSAGPA
>>CCDS42845.1 RSPO4 gene_id:343637|Hs108|chr20 (172 aa)
initn: 484 init1: 245 opt: 460 Z-score: 397.3 bits: 80.6 E(32554): 8.3e-16
Smith-Waterman score: 460; 42.3% identity (69.1% similar) in 149 aa overlap (1-147:1-142)
10 20 30 40 50 60
pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL
:: ::.. :: . . .: :...... . :. :: .::: ::: :. .:
CCDS42 MRAPLCLLLLVAHAVDMLALNR-----RKKQVGTGLGGNCT-GCIICSEENGCSTCQQRL
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL
:....:. ::: : :: .:::::: :. ..:.: :: ::.:::..:: .::. .::
CCDS42 FLFIRREGIRQYGKCLHDCPPGYFGIRGQEVNRCKKCGAT-CESCFSQDFCIRCKRQFYL
60 70 80 90 100 110
130 140 150 160 170
pF1KE2 HKGRCYPACPEGSSAANGTMECS--SPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRR
.::.: :.:: :. : ..: ::. ::.:
CCDS42 YKGKCLPTCPPGTLAHQNTRECQERSPGQKKGRKDRRPRKDRKLDRRLDVRPRQPGLQP
120 130 140 150 160 170
263 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:58:31 2016 done: Mon Nov 7 20:58:31 2016
Total Scan time: 2.190 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]