FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2493, 263 aa 1>>>pF1KE2493 263 - 263 aa - 263 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2438+/-0.000337; mu= 12.4326+/- 0.021 mean_var=150.0131+/-29.647, 0's: 0 Z-trim(120.6): 91 B-trim: 0 in 0/51 Lambda= 0.104715 statistics sampled from 36018 (36125) to 36018 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.424), width: 16 Scan time: 5.870 The best scores are: opt bits E(85289) NP_001033722 (OMIM: 609595,610644) R-spondin-1 iso ( 263) 1898 297.8 1.4e-80 XP_006710646 (OMIM: 609595,610644) PREDICTED: R-sp ( 263) 1898 297.8 1.4e-80 NP_001229837 (OMIM: 609595,610644) R-spondin-1 iso ( 263) 1898 297.8 1.4e-80 NP_001229838 (OMIM: 609595,610644) R-spondin-1 iso ( 236) 1701 267.9 1.2e-71 NP_001229839 (OMIM: 609595,610644) R-spondin-1 iso ( 200) 1066 171.9 7.9e-43 NP_116173 (OMIM: 610574) R-spondin-3 precursor [Ho ( 272) 885 144.7 1.6e-34 XP_016866867 (OMIM: 610574) PREDICTED: R-spondin-3 ( 224) 840 137.8 1.6e-32 XP_016868884 (OMIM: 610575) PREDICTED: R-spondin-2 ( 242) 745 123.5 3.6e-28 NP_848660 (OMIM: 610575) R-spondin-2 isoform 1 pre ( 243) 744 123.4 4e-28 XP_011515321 (OMIM: 610575) PREDICTED: R-spondin-2 ( 249) 733 121.7 1.3e-27 XP_011515320 (OMIM: 610575) PREDICTED: R-spondin-2 ( 250) 732 121.6 1.4e-27 XP_016866868 (OMIM: 610574) PREDICTED: R-spondin-3 ( 203) 696 116.0 5.4e-26 NP_001025042 (OMIM: 206800,610573) R-spondin-4 iso ( 234) 652 109.5 5.9e-24 XP_016883328 (OMIM: 206800,610573) PREDICTED: R-sp ( 266) 629 106.0 7.1e-23 NP_001304871 (OMIM: 610575) R-spondin-2 isoform 3 ( 176) 610 103.0 4e-22 NP_001269792 (OMIM: 610575) R-spondin-2 isoform 2 ( 179) 475 82.6 5.5e-16 NP_001035096 (OMIM: 206800,610573) R-spondin-4 iso ( 172) 460 80.3 2.6e-15 XP_011517072 (OMIM: 600488) PREDICTED: proprotein (1441) 255 50.4 2.2e-05 XP_016870289 (OMIM: 600488) PREDICTED: proprotein (1450) 255 50.4 2.2e-05 XP_011517071 (OMIM: 600488) PREDICTED: proprotein (1886) 255 50.5 2.6e-05 XP_005252096 (OMIM: 600488) PREDICTED: proprotein (1887) 255 50.5 2.6e-05 NP_001177411 (OMIM: 600488) proprotein convertase (1860) 254 50.4 2.9e-05 NP_001278238 (OMIM: 167405) proprotein convertase ( 895) 232 46.7 0.00018 NP_612192 (OMIM: 167405) proprotein convertase sub ( 956) 232 46.7 0.00019 NP_002561 (OMIM: 167405) proprotein convertase sub ( 969) 232 46.7 0.00019 NP_006191 (OMIM: 600488) proprotein convertase sub ( 913) 222 45.2 0.00052 >>NP_001033722 (OMIM: 609595,610644) R-spondin-1 isoform (263 aa) initn: 1898 init1: 1898 opt: 1898 Z-score: 1567.8 bits: 297.8 E(85289): 1.4e-80 Smith-Waterman score: 1898; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263) 10 20 30 40 50 60 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR 190 200 210 220 230 240 250 260 pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA ::::::::::::::::::::::: NP_001 RRKGQQQQQQQGTVGPLTSAGPA 250 260 >>XP_006710646 (OMIM: 609595,610644) PREDICTED: R-spondi (263 aa) initn: 1898 init1: 1898 opt: 1898 Z-score: 1567.8 bits: 297.8 E(85289): 1.4e-80 Smith-Waterman score: 1898; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263) 10 20 30 40 50 60 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR 190 200 210 220 230 240 250 260 pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA ::::::::::::::::::::::: XP_006 RRKGQQQQQQQGTVGPLTSAGPA 250 260 >>NP_001229837 (OMIM: 609595,610644) R-spondin-1 isoform (263 aa) initn: 1898 init1: 1898 opt: 1898 Z-score: 1567.8 bits: 297.8 E(85289): 1.4e-80 Smith-Waterman score: 1898; 100.0% identity (100.0% similar) in 263 aa overlap (1-263:1-263) 10 20 30 40 50 60 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR 190 200 210 220 230 240 250 260 pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA ::::::::::::::::::::::: NP_001 RRKGQQQQQQQGTVGPLTSAGPA 250 260 >>NP_001229838 (OMIM: 609595,610644) R-spondin-1 isoform (236 aa) initn: 1701 init1: 1701 opt: 1701 Z-score: 1407.5 bits: 267.9 E(85289): 1.2e-71 Smith-Waterman score: 1701; 99.6% identity (100.0% similar) in 233 aa overlap (31-263:4-236) 10 20 30 40 50 60 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL :.:::::::::::::::::::::::::::: NP_001 MIFRVSAEGSQACAKGCELCSEVNGCLKCSPKL 10 20 30 70 80 90 100 110 120 pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL 100 110 120 130 140 150 190 200 210 220 230 240 pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR 160 170 180 190 200 210 250 260 pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA ::::::::::::::::::::::: NP_001 RRKGQQQQQQQGTVGPLTSAGPA 220 230 >>NP_001229839 (OMIM: 609595,610644) R-spondin-1 isoform (200 aa) initn: 1109 init1: 1066 opt: 1066 Z-score: 889.9 bits: 171.9 E(85289): 7.9e-43 Smith-Waterman score: 1288; 76.0% identity (76.0% similar) in 263 aa overlap (1-263:1-200) 10 20 30 40 50 60 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL ::::::::::::::::::::::::: NP_001 HKGRCYPACPEGSSAANGTMECSSP----------------------------------- 130 140 190 200 210 220 230 240 pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR :::::::::::::::::::::::::::::::: NP_001 ----------------------------GQKRRKGGQGRRENANRNLARKESKEAGAGSR 150 160 170 250 260 pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA ::::::::::::::::::::::: NP_001 RRKGQQQQQQQGTVGPLTSAGPA 180 190 200 >>NP_116173 (OMIM: 610574) R-spondin-3 precursor [Homo s (272 aa) initn: 881 init1: 508 opt: 885 Z-score: 740.5 bits: 144.7 E(85289): 1.6e-34 Smith-Waterman score: 885; 46.0% identity (72.2% similar) in 252 aa overlap (10-251:11-257) 10 20 30 40 50 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPK ..:.. . :. . .:.::::. . ::.: :: ::. ::::.:.:. NP_116 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 LFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLY ::. ::: ..:.:::: ::: ::. .: ::.::: ::: . :..::..::::::: :.: NP_116 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFY 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 LHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRV :: :.: :::: : : :::: : ..::.:::.::.::.:: . :::.::.: :.:.. NP_116 LHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 LHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGS .. : . : :.:::.:::.: : .:.. .:: . .:.. :.. ::::: : NP_116 IQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGKKGRERKRKKPNKG----ESKEAIPDS 180 190 200 210 220 230 240 250 260 pF1KE2 R----------RRKGQQQQQQQGTVGPLTSAGPA . .:...:::... NP_116 KSLESSKEIPEQRENKQQQKKRKVQDKQKSVSVSTVH 240 250 260 270 >>XP_016866867 (OMIM: 610574) PREDICTED: R-spondin-3 iso (224 aa) initn: 847 init1: 480 opt: 840 Z-score: 704.8 bits: 137.8 E(85289): 1.6e-32 Smith-Waterman score: 840; 50.5% identity (75.5% similar) in 204 aa overlap (10-213:11-213) 10 20 30 40 50 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPK ..:.. . :. . .:.::::. . ::.: :: ::. ::::.:.:. XP_016 MHLRLISWLFIILNFMEYIGSQNASRGRRQRRMHPNVSQGCQGGCATCSDYNGCLSCKPR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 LFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLY ::. ::: ..:.:::: ::: ::. .: ::.::: ::: . :..::..::::::: :.: XP_016 LFFALERIGMKQIGVCLSSCPSGYYGTRYPDINKCTKCKAD-CDTCFNKNFCTKCKSGFY 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 LHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRV :: :.: :::: : : :::: : ..::.:::.::.::.:: . :::.::.: :.:.. XP_016 LHLGKCLDNCPEGLEANNHTMECVSIVHCEVSEWNPWSPCTKKGKTCGFKRGTETRVREI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 LHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGS .. : . : :.:::.:::.: : .:.. : XP_016 IQHPSAKGNLCPPTNETRKCTVQRKKCQKGERGRTSRGDERCFNH 180 190 200 210 220 240 250 260 pF1KE2 RRRKGQQQQQQQGTVGPLTSAGPA >>XP_016868884 (OMIM: 610575) PREDICTED: R-spondin-2 iso (242 aa) initn: 735 init1: 497 opt: 745 Z-score: 626.8 bits: 123.5 E(85289): 3.6e-28 Smith-Waterman score: 745; 41.5% identity (67.9% similar) in 234 aa overlap (1-234:1-230) 10 20 30 40 50 60 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL :.. : ::.. .: . .:..: : .. : ::: ::. ::: .:. :: XP_016 MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPIC-KGCLSCSKDNGCSRCQQKL 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL :..:.:. .:: : :: ::: ::. : ::::.: .:.::.:..:::..:::::: :.:: XP_016 FFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL :.:::. ::.: . . :::: . ::...:: :: ::.... :::. : : :::... XP_016 HRGRCFDECPDGFAPLEETMEC---VGCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR . :: : : :.::: . :: :.. :. . : .. .:.: .. ... XP_016 KKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLA 180 190 200 210 220 230 250 260 pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA XP_016 TDRANQ 240 >>NP_848660 (OMIM: 610575) R-spondin-2 isoform 1 precurs (243 aa) initn: 723 init1: 485 opt: 744 Z-score: 626.0 bits: 123.4 E(85289): 4e-28 Smith-Waterman score: 744; 41.5% identity (67.5% similar) in 234 aa overlap (1-234:1-231) 10 20 30 40 50 60 pF1KE2 MRLGLCVVALVLSWTHLTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNGCLKCSPKL :.. : ::.. .: . .:..: : .. : ::: ::. ::: .:. :: NP_848 MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPIC-KGCLSCSKDNGCSRCQQKL 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 FILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYL :..:.:. .:: : :: ::: ::. : ::::.: .:.::.:..:::..:::::: :.:: NP_848 FFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 HKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGSEERTRRVL :.:::. ::.: . . :::: ::...:: :: ::.... :::. : : :::... NP_848 HRGRCFDECPDGFAPLEETMECVE--GCEVGHWSEWGTCSRNNRTCGFKWGLETRTRQIV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 HAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKESKEAGAGSR . :: : : :.::: . :: :.. :. . : .. .:.: .. ... NP_848 KKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLA 180 190 200 210 220 230 250 260 pF1KE2 RRKGQQQQQQQGTVGPLTSAGPA NP_848 TDRANQ 240 >>XP_011515321 (OMIM: 610575) PREDICTED: R-spondin-2 iso (249 aa) initn: 735 init1: 497 opt: 733 Z-score: 616.9 bits: 121.7 E(85289): 1.3e-27 Smith-Waterman score: 733; 41.3% identity (68.6% similar) in 242 aa overlap (1-234:1-237) 10 20 30 40 50 pF1KE2 MRLGLCVVALV----LSWTHLTISSRGIKGKRQRRISAEGSQA----CAKGCELCSEVNG :.. : ::. ....: ..: ..:: .::..: . : ::: ::. :: XP_011 MQFRLFSFALIILNCMDYSHCQ-GNRWRRSKRGGSLSAKASYVSNPIC-KGCLSCSKDNG 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 CLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNFCT : .:. :::..:.:. .:: : :: ::: ::. : ::::.: .:.::.:..:::..::: XP_011 CSRCQQKLFFFLRREGMRQYGECLHSCPSGYYGHRAPDMNRCARCRIENCDSCFSKDFCT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 KCKEGLYLHKGRCYPACPEGSSAANGTMECSSPAQCEMSEWSPWGPCSKKQQLCGFRRGS ::: :.:::.:::. ::.: . . :::: . ::...:: :: ::.... :::. : XP_011 KCKVGFYLHRGRCFDECPDGFAPLEETMEC---VGCEVGHWSEWGTCSRNNRTCGFKWGL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 EERTRRVLHAPVGDHAACSDTKETRRCTVRRVPCPEGQKRRKGGQGRRENANRNLARKES : :::.... :: : : :.::: . :: :.. :. . : .. .:.: .. . XP_011 ETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQ 180 190 200 210 220 230 240 250 260 pF1KE2 KEAGAGSRRRKGQQQQQQQGTVGPLTSAGPA .. XP_011 EQHSVFLATDRANQ 240 263 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 20:58:32 2016 done: Mon Nov 7 20:58:32 2016 Total Scan time: 5.870 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]