FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2502, 724 aa 1>>>pF1KE2502 724 - 724 aa - 724 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0484+/-0.000469; mu= 15.3568+/- 0.029 mean_var=81.2011+/-16.412, 0's: 0 Z-trim(110.0): 124 B-trim: 0 in 0/49 Lambda= 0.142329 statistics sampled from 18108 (18238) to 18108 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.574), E-opt: 0.2 (0.214), width: 16 Scan time: 8.940 The best scores are: opt bits E(85289) NP_055977 (OMIM: 614362) long-chain-fatty-acid--Co ( 724) 4859 1008.5 0 NP_001186306 (OMIM: 614362) long-chain-fatty-acid- ( 720) 4817 999.8 0 XP_016877514 (OMIM: 614362) PREDICTED: long-chain- ( 748) 4779 992.0 0 XP_016877515 (OMIM: 614362) PREDICTED: long-chain- ( 732) 4566 948.3 0 XP_011519692 (OMIM: 614362) PREDICTED: long-chain- ( 702) 4565 948.1 0 XP_011519693 (OMIM: 614362) PREDICTED: long-chain- ( 677) 4257 884.8 0 NP_112186 (OMIM: 614363) long-chain-fatty-acid--Co ( 666) 2177 457.7 6.7e-128 NP_001276107 (OMIM: 614363) long-chain-fatty-acid- ( 666) 2177 457.7 6.7e-128 NP_001276106 (OMIM: 614363) long-chain-fatty-acid- ( 666) 2177 457.7 6.7e-128 XP_016882821 (OMIM: 614363) PREDICTED: long-chain- ( 666) 2177 457.7 6.7e-128 NP_001308313 (OMIM: 614363) long-chain-fatty-acid- ( 616) 2119 445.8 2.4e-124 XP_016882822 (OMIM: 614363) PREDICTED: long-chain- ( 651) 2095 440.9 7.7e-123 NP_001276108 (OMIM: 614363) long-chain-fatty-acid- ( 638) 1862 393.0 1.9e-108 XP_005259710 (OMIM: 614363) PREDICTED: long-chain- ( 566) 1831 386.6 1.4e-106 NP_001276109 (OMIM: 614363) long-chain-fatty-acid- ( 479) 1714 362.6 2.1e-99 XP_011526631 (OMIM: 614363) PREDICTED: long-chain- ( 459) 1480 314.5 5.9e-85 XP_016882823 (OMIM: 614363) PREDICTED: long-chain- ( 610) 1301 277.8 8.7e-74 NP_976314 (OMIM: 605677) long-chain-fatty-acid--Co ( 683) 575 128.8 7.2e-29 NP_976313 (OMIM: 605677) long-chain-fatty-acid--Co ( 683) 575 128.8 7.2e-29 XP_005262886 (OMIM: 152425) PREDICTED: long-chain- ( 698) 575 128.8 7.3e-29 NP_001986 (OMIM: 152425) long-chain-fatty-acid--Co ( 698) 575 128.8 7.3e-29 XP_016863376 (OMIM: 152425) PREDICTED: long-chain- ( 698) 575 128.8 7.3e-29 XP_011530044 (OMIM: 152425) PREDICTED: long-chain- ( 698) 575 128.8 7.3e-29 XP_005262885 (OMIM: 152425) PREDICTED: long-chain- ( 698) 575 128.8 7.3e-29 XP_005262888 (OMIM: 152425) PREDICTED: long-chain- ( 698) 575 128.8 7.3e-29 NP_001273637 (OMIM: 152425) long-chain-fatty-acid- ( 698) 575 128.8 7.3e-29 NP_057318 (OMIM: 605677) long-chain-fatty-acid--Co ( 739) 575 128.8 7.7e-29 XP_016863377 (OMIM: 152425) PREDICTED: long-chain- ( 698) 574 128.6 8.5e-29 NP_001273639 (OMIM: 152425) long-chain-fatty-acid- ( 698) 574 128.6 8.5e-29 XP_016863378 (OMIM: 152425) PREDICTED: long-chain- ( 698) 574 128.6 8.5e-29 XP_016871813 (OMIM: 605677) PREDICTED: long-chain- ( 715) 566 126.9 2.7e-28 NP_001192179 (OMIM: 604443) long-chain-fatty-acid- ( 708) 565 126.7 3.1e-28 NP_001009185 (OMIM: 604443) long-chain-fatty-acid- ( 722) 565 126.7 3.1e-28 NP_001192176 (OMIM: 604443) long-chain-fatty-acid- ( 687) 564 126.5 3.5e-28 NP_001192177 (OMIM: 604443) long-chain-fatty-acid- ( 697) 564 126.5 3.5e-28 NP_056071 (OMIM: 604443) long-chain-fatty-acid--Co ( 722) 564 126.5 3.6e-28 NP_001273640 (OMIM: 152425) long-chain-fatty-acid- ( 664) 506 114.6 1.3e-24 NP_001273641 (OMIM: 152425) long-chain-fatty-acid- ( 527) 499 113.1 2.9e-24 NP_976251 (OMIM: 602371) long-chain-fatty-acid--Co ( 720) 438 100.7 2.2e-20 NP_004448 (OMIM: 602371) long-chain-fatty-acid--Co ( 720) 438 100.7 2.2e-20 XP_016859073 (OMIM: 602371) PREDICTED: long-chain- ( 720) 438 100.7 2.2e-20 NP_001305439 (OMIM: 300157,300387) long-chain-fatt ( 670) 387 90.2 3e-17 XP_006724698 (OMIM: 300157,300387) PREDICTED: long ( 670) 387 90.2 3e-17 NP_004449 (OMIM: 300157,300387) long-chain-fatty-a ( 670) 387 90.2 3e-17 NP_075266 (OMIM: 300157,300387) long-chain-fatty-a ( 711) 387 90.2 3.1e-17 NP_001305438 (OMIM: 300157,300387) long-chain-fatt ( 711) 387 90.2 3.1e-17 XP_005262166 (OMIM: 300157,300387) PREDICTED: long ( 711) 387 90.2 3.1e-17 XP_011529190 (OMIM: 300157,300387) PREDICTED: long ( 711) 387 90.2 3.1e-17 XP_011529191 (OMIM: 300157,300387) PREDICTED: long ( 711) 387 90.2 3.1e-17 NP_001192180 (OMIM: 604443) long-chain-fatty-acid- ( 622) 317 75.8 5.9e-13 >>NP_055977 (OMIM: 614362) long-chain-fatty-acid--CoA li (724 aa) initn: 4859 init1: 4859 opt: 4859 Z-score: 5393.0 bits: 1008.5 E(85289): 0 Smith-Waterman score: 4859; 99.9% identity (100.0% similar) in 724 aa overlap (1-724:1-724) 10 20 30 40 50 60 pF1KE2 MPRNSGAGYGCPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MPRNSGAGYGCPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 LELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 LELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 ALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 ALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 GGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 NKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 NKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNIT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 WTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 WTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 VNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 VNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 KPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 GPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 GPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 DEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 DEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 GDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTVSEIIEKKDEAVYQA ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: NP_055 GDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 IEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 IEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQ 670 680 690 700 710 720 pF1KE2 EQKM :::: NP_055 EQKM >>NP_001186306 (OMIM: 614362) long-chain-fatty-acid--CoA (720 aa) initn: 3814 init1: 3814 opt: 4817 Z-score: 5346.4 bits: 999.8 E(85289): 0 Smith-Waterman score: 4817; 99.3% identity (99.4% similar) in 724 aa overlap (1-724:1-720) 10 20 30 40 50 60 pF1KE2 MPRNSGAGYGCPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPRNSGAGYGCPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 LELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 ALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFA ::::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 ALGFKRQDKWEHISYSQYYLLARRAAKGFLK----QAHSVAILGFNSPEWFFSAVGTVFA 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 GGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KE2 NKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNIT 240 250 260 270 280 290 310 320 330 340 350 360 pF1KE2 WTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSL 300 310 320 330 340 350 370 380 390 400 410 420 pF1KE2 VNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDL 360 370 380 390 400 410 430 440 450 460 470 480 pF1KE2 KPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETS 420 430 440 450 460 470 490 500 510 520 530 540 pF1KE2 GPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAI 480 490 500 510 520 530 550 560 570 580 590 600 pF1KE2 DEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLI 540 550 560 570 580 590 610 620 630 640 650 660 pF1KE2 GDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTVSEIIEKKDEAVYQA ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: NP_001 GDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQA 600 610 620 630 640 650 670 680 690 700 710 720 pF1KE2 IEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQ 660 670 680 690 700 710 pF1KE2 EQKM :::: NP_001 EQKM 720 >>XP_016877514 (OMIM: 614362) PREDICTED: long-chain-fatt (748 aa) initn: 4779 init1: 4779 opt: 4779 Z-score: 5304.0 bits: 992.0 E(85289): 0 Smith-Waterman score: 4779; 99.9% identity (100.0% similar) in 712 aa overlap (1-712:1-712) 10 20 30 40 50 60 pF1KE2 MPRNSGAGYGCPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MPRNSGAGYGCPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 LELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 ALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 GGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 NKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNIT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 WTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 VNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 KPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETS 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 GPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 DEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 GDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTVSEIIEKKDEAVYQA ::::::::::::::::::::::::::::::::.::::::::::::::::::::::::::: XP_016 GDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 IEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQ :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKDGVSLCCP 670 680 690 700 710 720 pF1KE2 EQKM XP_016 GWSAVARSQLTTTSASWVQAILLPQRPE 730 740 >>XP_016877515 (OMIM: 614362) PREDICTED: long-chain-fatt (732 aa) initn: 4566 init1: 4566 opt: 4566 Z-score: 5067.8 bits: 948.3 E(85289): 0 Smith-Waterman score: 4566; 99.4% identity (100.0% similar) in 684 aa overlap (41-724:49-732) 20 30 40 50 60 70 pF1KE2 CPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHALELSVPEKVN ...::::::::::::::::::::::::::: XP_016 LSRWLPGGPRCVHKLSFVRNLQCRQGVRLNVRSSSLTDRQPLSKESLNHALELSVPEKVN 20 30 40 50 60 70 80 90 100 110 120 130 pF1KE2 NAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLIALGFKRQDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLIALGFKRQDKW 80 90 100 110 120 130 140 150 160 170 180 190 pF1KE2 EHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTT 140 150 160 170 180 190 200 210 220 230 240 250 pF1KE2 SSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMANVYTME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMANVYTME 200 210 220 230 240 250 260 270 280 290 300 310 pF1KE2 EFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAG 260 270 280 290 300 310 320 330 340 350 360 370 pF1KE2 DIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPT 320 330 340 350 360 370 380 390 400 410 420 430 pF1KE2 SHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADY 380 390 400 410 420 430 440 450 460 470 480 490 pF1KE2 LVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETSGPHFMSSPYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETSGPHFMSSPYN 440 450 460 470 480 490 500 510 520 530 540 550 pF1KE2 YRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGD 500 510 520 530 540 550 560 570 580 590 600 610 pF1KE2 AGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSML 560 570 580 590 600 610 620 630 640 650 660 670 pF1KE2 LTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNM ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_016 LTLKCTLDPDTSDQTDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNM 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 NAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQEQKM :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQEQKM 680 690 700 710 720 730 >>XP_011519692 (OMIM: 614362) PREDICTED: long-chain-fatt (702 aa) initn: 4565 init1: 4565 opt: 4565 Z-score: 5066.9 bits: 948.1 E(85289): 0 Smith-Waterman score: 4565; 99.6% identity (99.9% similar) in 684 aa overlap (41-724:19-702) 20 30 40 50 60 70 pF1KE2 CPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHALELSVPEKVN :. ::::::::::::::::::::::::::: XP_011 MNRLEPLHLAHYYSLILNLEISSLTDRQPLSKESLNHALELSVPEKVN 10 20 30 40 80 90 100 110 120 130 pF1KE2 NAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLIALGFKRQDKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLIALGFKRQDKW 50 60 70 80 90 100 140 150 160 170 180 190 pF1KE2 EHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTT 110 120 130 140 150 160 200 210 220 230 240 250 pF1KE2 SSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMANVYTME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMANVYTME 170 180 190 200 210 220 260 270 280 290 300 310 pF1KE2 EFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAG 230 240 250 260 270 280 320 330 340 350 360 370 pF1KE2 DIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPT 290 300 310 320 330 340 380 390 400 410 420 430 pF1KE2 SHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADY 350 360 370 380 390 400 440 450 460 470 480 490 pF1KE2 LVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETSGPHFMSSPYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETSGPHFMSSPYN 410 420 430 440 450 460 500 510 520 530 540 550 pF1KE2 YRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGD 470 480 490 500 510 520 560 570 580 590 600 610 pF1KE2 AGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSML 530 540 550 560 570 580 620 630 640 650 660 670 pF1KE2 LTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNM ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: XP_011 LTLKCTLDPDTSDQTDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNM 590 600 610 620 630 640 680 690 700 710 720 pF1KE2 NAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQEQKM :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQEQKM 650 660 670 680 690 700 >>XP_011519693 (OMIM: 614362) PREDICTED: long-chain-fatt (677 aa) initn: 4257 init1: 4257 opt: 4257 Z-score: 4725.4 bits: 884.8 E(85289): 0 Smith-Waterman score: 4257; 99.8% identity (100.0% similar) in 635 aa overlap (78-712:7-641) 50 60 70 80 90 100 pF1KE2 DRQPLSKESLNHALELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHR :::::::::::::::::::::::::::::: XP_011 MGEEKLEEALWTTRADGRVRLRIDPSCPQLPYTVHR 10 20 30 110 120 130 140 150 160 pF1KE2 MFYEALDKYGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MFYEALDKYGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNS 40 50 60 70 80 90 170 180 190 200 210 220 pF1KE2 PEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLP 100 110 120 130 140 150 230 240 250 260 270 280 pF1KE2 HLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTG 160 170 180 190 200 210 290 300 310 320 330 340 pF1KE2 NPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQ 220 230 240 250 260 270 350 360 370 380 390 400 pF1KE2 VCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSV 280 290 300 310 320 330 410 420 430 440 450 460 pF1KE2 TLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLN 340 350 360 370 380 390 470 480 490 500 510 520 pF1KE2 IRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFM 400 410 420 430 440 450 530 540 550 560 570 580 pF1KE2 GYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAV 460 470 480 490 500 510 590 600 610 620 630 640 pF1KE2 KMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTVS :::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::: XP_011 KMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEFCQRVGSRATTVS 520 530 540 550 560 570 650 660 670 680 690 700 pF1KE2 EIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTV 580 590 600 610 620 630 710 720 pF1KE2 LEKYKGIIDSFYQEQKM ::::: XP_011 LEKYKDGVSLCCPGWSAVARSQLTTTSASWVQAILLPQRPE 640 650 660 670 >>NP_112186 (OMIM: 614363) long-chain-fatty-acid--CoA li (666 aa) initn: 2083 init1: 1120 opt: 2177 Z-score: 2417.2 bits: 457.7 E(85289): 6.7e-128 Smith-Waterman score: 2177; 50.6% identity (78.3% similar) in 644 aa overlap (81-720:27-666) 60 70 80 90 100 pF1KE2 PLSKESLNHALELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCP--QLPYTVHRM :::: ::.: ::.. : . :.:. .. NP_112 MTGTPKTQEGAKDLEVDMNKTEVTPRLWTTCRDGEVLLRLSKHGPGHETPMTIPEF 10 20 30 40 50 110 120 130 140 150 160 pF1KE2 FYEALDKYGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSP : :.....: ::. : ::: ....::: :.:::...::::.. :.:.:::::: NP_112 FRESVNRFGTYPALASKNGKKWEILNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSA 60 70 80 90 100 110 170 180 190 200 210 220 pF1KE2 EWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKI-WKQLP :::..:::...:::. .:::.:.: :.:::. .:...:....::.:::.: ..: NP_112 EWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLE 120 130 140 150 160 170 230 240 250 260 270 280 pF1KE2 HLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTG :::.. :. : .: :.:. ..::::: .:. :. .:..:. ::: ::.::::::: NP_112 PLKAIIQYRLPM-KKNNNLYSWDDFMELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTG 180 190 200 210 220 230 290 300 310 320 330 340 pF1KE2 NPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQ :::::::.::::: : :. . :.. .. ..:.:::::::::::::..:.:. :. :: NP_112 IPKGVMLSHDNITWIA--GAVTKDFKLTD-KHETVVSYLPLSHIAAQMMDIWVPIKIGAL 240 250 260 270 280 290 350 360 370 380 390 400 pF1KE2 VCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSV . ::. :::::.::.::.::.:: .:::..:::: : ... .:.: ...: ..:: .. NP_112 TYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNI 300 310 320 330 340 350 410 420 430 440 450 460 pF1KE2 TLEQNLTCP-GSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGL .. : :. : . :.: ::..::. .::. .:.. . :.::. :: .:::.: NP_112 GFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSL 360 370 380 390 400 410 470 480 490 500 510 520 pF1KE2 NIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIF .: . :::::.:::: .:. :::: : ::.. ::. : .:. .:::::::::: :: NP_112 DIPIGELYGLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWGRHIF 420 430 440 450 460 470 530 540 550 560 570 580 pF1KE2 MGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEA ::::. : .: ::::.:::::.:: :.::. ::::.::..::..::::::::::.:.: NP_112 MGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETL 480 490 500 510 520 530 590 600 610 620 630 640 pF1KE2 VKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTV :: ..::::::::.::. ::::::::::: .. ... :.:. .:..::. .::.:.:: NP_112 VKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTV 540 550 560 570 580 590 650 660 670 680 690 700 pF1KE2 SEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLT .::....: ::.::..:: ::..: .:.::.:::.:::: :::::: ::::: NP_112 TEIVKQQDPLVYKAIQQGINAVNQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHF 600 610 620 630 640 650 710 720 pF1KE2 VLEKYKGIIDSFYQEQKM : .::: :: .:. NP_112 VAQKYKKQIDHMYH 660 >>NP_001276107 (OMIM: 614363) long-chain-fatty-acid--CoA (666 aa) initn: 2083 init1: 1120 opt: 2177 Z-score: 2417.2 bits: 457.7 E(85289): 6.7e-128 Smith-Waterman score: 2177; 50.6% identity (78.3% similar) in 644 aa overlap (81-720:27-666) 60 70 80 90 100 pF1KE2 PLSKESLNHALELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCP--QLPYTVHRM :::: ::.: ::.. : . :.:. .. NP_001 MTGTPKTQEGAKDLEVDMNKTEVTPRLWTTCRDGEVLLRLSKHGPGHETPMTIPEF 10 20 30 40 50 110 120 130 140 150 160 pF1KE2 FYEALDKYGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSP : :.....: ::. : ::: ....::: :.:::...::::.. :.:.:::::: NP_001 FRESVNRFGTYPALASKNGKKWEILNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSA 60 70 80 90 100 110 170 180 190 200 210 220 pF1KE2 EWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKI-WKQLP :::..:::...:::. .:::.:.: :.:::. .:...:....::.:::.: ..: NP_001 EWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLE 120 130 140 150 160 170 230 240 250 260 270 280 pF1KE2 HLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTG :::.. :. : .: :.:. ..::::: .:. :. .:..:. ::: ::.::::::: NP_001 PLKAIIQYRLPM-KKNNNLYSWDDFMELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTG 180 190 200 210 220 230 290 300 310 320 330 340 pF1KE2 NPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQ :::::::.::::: : :. . :.. .. ..:.:::::::::::::..:.:. :. :: NP_001 IPKGVMLSHDNITWIA--GAVTKDFKLTD-KHETVVSYLPLSHIAAQMMDIWVPIKIGAL 240 250 260 270 280 290 350 360 370 380 390 400 pF1KE2 VCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSV . ::. :::::.::.::.::.:: .:::..:::: : ... .:.: ...: ..:: .. NP_001 TYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNI 300 310 320 330 340 350 410 420 430 440 450 460 pF1KE2 TLEQNLTCP-GSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGL .. : :. : . :.: ::..::. .::. .:.. . :.::. :: .:::.: NP_001 GFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSL 360 370 380 390 400 410 470 480 490 500 510 520 pF1KE2 NIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIF .: . :::::.:::: .:. :::: : ::.. ::. : .:. .:::::::::: :: NP_001 DIPIGELYGLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWGRHIF 420 430 440 450 460 470 530 540 550 560 570 580 pF1KE2 MGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEA ::::. : .: ::::.:::::.:: :.::. ::::.::..::..::::::::::.:.: NP_001 MGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETL 480 490 500 510 520 530 590 600 610 620 630 640 pF1KE2 VKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTV :: ..::::::::.::. ::::::::::: .. ... :.:. .:..::. .::.:.:: NP_001 VKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTV 540 550 560 570 580 590 650 660 670 680 690 700 pF1KE2 SEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLT .::....: ::.::..:: ::..: .:.::.:::.:::: :::::: ::::: NP_001 TEIVKQQDPLVYKAIQQGINAVNQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHF 600 610 620 630 640 650 710 720 pF1KE2 VLEKYKGIIDSFYQEQKM : .::: :: .:. NP_001 VAQKYKKQIDHMYH 660 >>NP_001276106 (OMIM: 614363) long-chain-fatty-acid--CoA (666 aa) initn: 2083 init1: 1120 opt: 2177 Z-score: 2417.2 bits: 457.7 E(85289): 6.7e-128 Smith-Waterman score: 2177; 50.6% identity (78.3% similar) in 644 aa overlap (81-720:27-666) 60 70 80 90 100 pF1KE2 PLSKESLNHALELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCP--QLPYTVHRM :::: ::.: ::.. : . :.:. .. NP_001 MTGTPKTQEGAKDLEVDMNKTEVTPRLWTTCRDGEVLLRLSKHGPGHETPMTIPEF 10 20 30 40 50 110 120 130 140 150 160 pF1KE2 FYEALDKYGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSP : :.....: ::. : ::: ....::: :.:::...::::.. :.:.:::::: NP_001 FRESVNRFGTYPALASKNGKKWEILNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSA 60 70 80 90 100 110 170 180 190 200 210 220 pF1KE2 EWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKI-WKQLP :::..:::...:::. .:::.:.: :.:::. .:...:....::.:::.: ..: NP_001 EWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLE 120 130 140 150 160 170 230 240 250 260 270 280 pF1KE2 HLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTG :::.. :. : .: :.:. ..::::: .:. :. .:..:. ::: ::.::::::: NP_001 PLKAIIQYRLPM-KKNNNLYSWDDFMELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTG 180 190 200 210 220 230 290 300 310 320 330 340 pF1KE2 NPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQ :::::::.::::: : :. . :.. .. ..:.:::::::::::::..:.:. :. :: NP_001 IPKGVMLSHDNITWIA--GAVTKDFKLTD-KHETVVSYLPLSHIAAQMMDIWVPIKIGAL 240 250 260 270 280 290 350 360 370 380 390 400 pF1KE2 VCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSV . ::. :::::.::.::.::.:: .:::..:::: : ... .:.: ...: ..:: .. NP_001 TYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNI 300 310 320 330 340 350 410 420 430 440 450 460 pF1KE2 TLEQNLTCP-GSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGL .. : :. : . :.: ::..::. .::. .:.. . :.::. :: .:::.: NP_001 GFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSL 360 370 380 390 400 410 470 480 490 500 510 520 pF1KE2 NIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIF .: . :::::.:::: .:. :::: : ::.. ::. : .:. .:::::::::: :: NP_001 DIPIGELYGLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWGRHIF 420 430 440 450 460 470 530 540 550 560 570 580 pF1KE2 MGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEA ::::. : .: ::::.:::::.:: :.::. ::::.::..::..::::::::::.:.: NP_001 MGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETL 480 490 500 510 520 530 590 600 610 620 630 640 pF1KE2 VKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTV :: ..::::::::.::. ::::::::::: .. ... :.:. .:..::. .::.:.:: NP_001 VKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTV 540 550 560 570 580 590 650 660 670 680 690 700 pF1KE2 SEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLT .::....: ::.::..:: ::..: .:.::.:::.:::: :::::: ::::: NP_001 TEIVKQQDPLVYKAIQQGINAVNQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHF 600 610 620 630 640 650 710 720 pF1KE2 VLEKYKGIIDSFYQEQKM : .::: :: .:. NP_001 VAQKYKKQIDHMYH 660 >>XP_016882821 (OMIM: 614363) PREDICTED: long-chain-fatt (666 aa) initn: 2083 init1: 1120 opt: 2177 Z-score: 2417.2 bits: 457.7 E(85289): 6.7e-128 Smith-Waterman score: 2177; 50.6% identity (78.3% similar) in 644 aa overlap (81-720:27-666) 60 70 80 90 100 pF1KE2 PLSKESLNHALELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCP--QLPYTVHRM :::: ::.: ::.. : . :.:. .. XP_016 MTGTPKTQEGAKDLEVDMNKTEVTPRLWTTCRDGEVLLRLSKHGPGHETPMTIPEF 10 20 30 40 50 110 120 130 140 150 160 pF1KE2 FYEALDKYGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSP : :.....: ::. : ::: ....::: :.:::...::::.. :.:.:::::: XP_016 FRESVNRFGTYPALASKNGKKWEILNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSA 60 70 80 90 100 110 170 180 190 200 210 220 pF1KE2 EWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKI-WKQLP :::..:::...:::. .:::.:.: :.:::. .:...:....::.:::.: ..: XP_016 EWFITAVGAILAGGLCVGIYATNSAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLE 120 130 140 150 160 170 230 240 250 260 270 280 pF1KE2 HLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTG :::.. :. : .: :.:. ..::::: .:. :. .:..:. ::: ::.::::::: XP_016 PLKAIIQYRLPM-KKNNNLYSWDDFMELGRSIPDTQLEQVIESQKANQCAVLIYTSGTTG 180 190 200 210 220 230 290 300 310 320 330 340 pF1KE2 NPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQ :::::::.::::: : :. . :.. .. ..:.:::::::::::::..:.:. :. :: XP_016 IPKGVMLSHDNITWIA--GAVTKDFKLTD-KHETVVSYLPLSHIAAQMMDIWVPIKIGAL 240 250 260 270 280 290 350 360 370 380 390 400 pF1KE2 VCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSV . ::. :::::.::.::.::.:: .:::..:::: : ... .:.: ...: ..:: .. XP_016 TYFAQADALKGTLVSTLKEVKPTVFIGVPQIWEKIHEMVKKNSAKSMGLKKKAFVWARNI 300 310 320 330 340 350 410 420 430 440 450 460 pF1KE2 TLEQNLTCP-GSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGL .. : :. : . :.: ::..::. .::. .:.. . :.::. :: .:::.: XP_016 GFKVNSKKMLGKYNTPVSYRMAKTLVFSKVKTSLGLDHCHSFISGTAPLNQETAEFFLSL 360 370 380 390 400 410 470 480 490 500 510 520 pF1KE2 NIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIF .: . :::::.:::: .:. :::: : ::.. ::. : .:. .:::::::::: :: XP_016 DIPIGELYGLSESSGPHTISNQNNYRLLSCGKILTGCKNMLFQQNKDGIGEICLWGRHIF 420 430 440 450 460 470 530 540 550 560 570 580 pF1KE2 MGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEA ::::. : .: ::::.:::::.:: :.::. ::::.::..::..::::::::::.:.: XP_016 MGYLESETETTEAIDDEGWLHSGDLGQLDGLGFLYVTGHIKEILITAGGENVPPIPVETL 480 490 500 510 520 530 590 600 610 620 630 640 pF1KE2 VKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAVEFCQRVGSRATTV :: ..::::::::.::. ::::::::::: .. ... :.:. .:..::. .::.:.:: XP_016 VKKKIPIISNAMLVGDKLKFLSMLLTLKCEMNQMSGEPLDKLNFEAINFCRGLGSQASTV 540 550 560 570 580 590 650 660 670 680 690 700 pF1KE2 SEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLT .::....: ::.::..:: ::..: .:.::.:::.:::: :::::: ::::: XP_016 TEIVKQQDPLVYKAIQQGINAVNQEAMNNAQRIEKWVILEKDFSIYGGELGPMMKLKRHF 600 610 620 630 640 650 710 720 pF1KE2 VLEKYKGIIDSFYQEQKM : .::: :: .:. XP_016 VAQKYKKQIDHMYH 660 724 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 02:22:08 2016 done: Thu Nov 3 02:22:09 2016 Total Scan time: 8.940 Total Display time: 0.140 Function used was FASTA [36.3.4 Apr, 2011]