FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2521, 551 aa 1>>>pF1KE2521 551 - 551 aa - 551 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2384+/-0.000943; mu= 1.7241+/- 0.057 mean_var=211.6840+/-43.621, 0's: 0 Z-trim(111.9): 24 B-trim: 108 in 1/53 Lambda= 0.088152 statistics sampled from 12737 (12753) to 12737 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.392), width: 16 Scan time: 3.880 The best scores are: opt bits E(32554) CCDS758.1 PALMD gene_id:54873|Hs108|chr1 ( 551) 3616 472.6 5.2e-133 CCDS48002.2 PALM2 gene_id:114299|Hs108|chr9 ( 411) 581 86.6 6.4e-17 >>CCDS758.1 PALMD gene_id:54873|Hs108|chr1 (551 aa) initn: 3616 init1: 3616 opt: 3616 Z-score: 2501.4 bits: 472.6 E(32554): 5.2e-133 Smith-Waterman score: 3616; 100.0% identity (100.0% similar) in 551 aa overlap (1-551:1-551) 10 20 30 40 50 60 pF1KE2 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSGKE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTEDI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 IRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 IRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEIKV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 EKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 EKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVEVE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 ELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 ELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGVNE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 SIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 DAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFMGY 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 QQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 QQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTGDGTEDPSLTALR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LPRKRSEASPHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDAQTTGDGTEDPSLTALR 490 500 510 520 530 540 550 pF1KE2 MRMAKLGKKVI ::::::::::: CCDS75 MRMAKLGKKVI 550 >>CCDS48002.2 PALM2 gene_id:114299|Hs108|chr9 (411 aa) initn: 666 init1: 232 opt: 581 Z-score: 417.2 bits: 86.6 E(32554): 6.4e-17 Smith-Waterman score: 614; 32.6% identity (53.8% similar) in 513 aa overlap (1-497:1-402) 10 20 30 40 50 pF1KE2 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSG-- : :::: : :::::..::: : :: :: ...:. : :: :.:.:::::::.:: .: CCDS48 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE .:.: ..:...:. ... ::..: :::.::: ::. : :::.::. ::.::: :.. . CCDS48 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE2 DIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEI :. .. . .... : ...:::: . :: . .: . :.::::: CCDS48 DFQKGFS----STDGDAVNYISSQLPDLP--ILCSRTAEP--SPGQDGTSRAAAVYAMEI 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 KVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVE .:::: .:::. .::. . . . :.:::::: : :: : :. ... ::. :. . CCDS48 NVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 VEELLRQASERNSKSPTEYHEPVYANPFYRPTTPQRETVTPGPNFQERIKIKTNGLGIGV ::::...:.. . : . .:: : ..:. CCDS48 VEELIQKAGQSS---------------------------LGGGHVSERTVIADGSLS--- 240 250 260 300 310 320 330 340 350 pF1KE2 NESIHNMGNGLSEERGNNFNHISPIPPVPHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQ ::. . : ::. .: . CCDS48 -----------------------------HPKEHMLCKEAKLEMVHK------------S 270 280 360 370 380 390 400 410 pF1KE2 DKDAPSPKPRLSPRETIFGKSEHQNSSPTCQEDEEDVRYNIVHSLPPDINDTEPVTMIFM :: : .: :. : ..:. . :. : .::::::: CCDS48 RKDHSSGNP---------GQ---QAQAPS--------------AAGPEANLDQPVTMIFM 290 300 310 420 430 440 450 460 pF1KE2 GYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEE-------------DEGEAEKPSYHP :::. :: :: :: : ::: :.::::.::...:. : . :: : .: CCDS48 GYQNIEDEEETKKVL-GYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRP 320 330 340 350 360 370 470 480 490 500 510 520 pF1KE2 IAPHSQVYQPAKPTPLPRKRSEAS-PHENTNHKSPHKNSISLKEQEESLGSPVHHSPFDA . :.. .:..: ...: :. : .:..: CCDS48 V---SDTTEPSSPE--GKEESLATEPAPGTQKKKRCQCCVVM 380 390 400 410 530 540 550 pF1KE2 QTTGDGTEDPSLTALRMRMAKLGKKVI 551 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 03:20:11 2016 done: Tue Nov 8 03:20:11 2016 Total Scan time: 3.880 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]