FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2536, 123 aa 1>>>pF1KE2536 123 - 123 aa - 123 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8499+/-0.000266; mu= 13.1526+/- 0.017 mean_var=60.1528+/-11.809, 0's: 0 Z-trim(119.9): 44 B-trim: 0 in 0/58 Lambda= 0.165366 statistics sampled from 34535 (34579) to 34535 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.782), E-opt: 0.2 (0.405), width: 16 Scan time: 3.910 The best scores are: opt bits E(85289) NP_777377 (OMIM: 609737) protein crumbs homolog 3 ( 123) 777 192.7 1.3e-49 XP_016882960 (OMIM: 609737) PREDICTED: protein cru ( 186) 777 192.8 1.8e-49 NP_777378 (OMIM: 609737) protein crumbs homolog 3 ( 120) 624 156.2 1.2e-38 NP_631900 (OMIM: 609737) protein crumbs homolog 3 ( 120) 624 156.2 1.2e-38 >>NP_777377 (OMIM: 609737) protein crumbs homolog 3 isof (123 aa) initn: 777 init1: 777 opt: 777 Z-score: 1011.8 bits: 192.7 E(85289): 1.3e-49 Smith-Waterman score: 777; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:1-123) 10 20 30 40 50 60 pF1KE2 MANPGLGLLLALGLPFLLARWGRAWGQIQTTSANENSTVLPSSTSSSSDGNLRPEAITAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_777 MANPGLGLLLALGLPFLLARWGRAWGQIQTTSANENSTVLPSSTSSSSDGNLRPEAITAI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 IVVFSLLAALLLAVGLALLVRKLREKRQTEGTYRPSSEEQFSHAAEARAPQDSKETVQGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_777 IVVFSLLAALLLAVGLALLVRKLREKRQTEGTYRPSSEEQFSHAAEARAPQDSKETVQGC 70 80 90 100 110 120 pF1KE2 LPI ::: NP_777 LPI >>XP_016882960 (OMIM: 609737) PREDICTED: protein crumbs (186 aa) initn: 777 init1: 777 opt: 777 Z-score: 1009.2 bits: 192.8 E(85289): 1.8e-49 Smith-Waterman score: 777; 100.0% identity (100.0% similar) in 123 aa overlap (1-123:64-186) 10 20 30 pF1KE2 MANPGLGLLLALGLPFLLARWGRAWGQIQT :::::::::::::::::::::::::::::: XP_016 PVAGAPGRRCGRRGEREKPLPRRCQPATQPMANPGLGLLLALGLPFLLARWGRAWGQIQT 40 50 60 70 80 90 40 50 60 70 80 90 pF1KE2 TSANENSTVLPSSTSSSSDGNLRPEAITAIIVVFSLLAALLLAVGLALLVRKLREKRQTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSANENSTVLPSSTSSSSDGNLRPEAITAIIVVFSLLAALLLAVGLALLVRKLREKRQTE 100 110 120 130 140 150 100 110 120 pF1KE2 GTYRPSSEEQFSHAAEARAPQDSKETVQGCLPI ::::::::::::::::::::::::::::::::: XP_016 GTYRPSSEEQFSHAAEARAPQDSKETVQGCLPI 160 170 180 >>NP_777378 (OMIM: 609737) protein crumbs homolog 3 isof (120 aa) initn: 621 init1: 621 opt: 624 Z-score: 814.7 bits: 156.2 E(85289): 1.2e-38 Smith-Waterman score: 624; 93.6% identity (95.5% similar) in 110 aa overlap (1-110:1-106) 10 20 30 40 50 60 pF1KE2 MANPGLGLLLALGLPFLLARWGRAWGQIQTTSANENSTVLPSSTSSSSDGNLRPEAITAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_777 MANPGLGLLLALGLPFLLARWGRAWGQIQTTSANENSTVLPSSTSSSSDGNLRPEAITAI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 IVVFSLLAALLLAVGLALLVRKLREKRQTEGTYRPSSEEQFSHAAEARAPQDSKETVQGC :::::::::::::::::::::::::::::::::::::::: . ::.: NP_777 IVVFSLLAALLLAVGLALLVRKLREKRQTEGTYRPSSEEQVG----ARVPPTPNLKLPPE 70 80 90 100 110 pF1KE2 LPI NP_777 ERLI 120 >>NP_631900 (OMIM: 609737) protein crumbs homolog 3 isof (120 aa) initn: 621 init1: 621 opt: 624 Z-score: 814.7 bits: 156.2 E(85289): 1.2e-38 Smith-Waterman score: 624; 93.6% identity (95.5% similar) in 110 aa overlap (1-110:1-106) 10 20 30 40 50 60 pF1KE2 MANPGLGLLLALGLPFLLARWGRAWGQIQTTSANENSTVLPSSTSSSSDGNLRPEAITAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_631 MANPGLGLLLALGLPFLLARWGRAWGQIQTTSANENSTVLPSSTSSSSDGNLRPEAITAI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 IVVFSLLAALLLAVGLALLVRKLREKRQTEGTYRPSSEEQFSHAAEARAPQDSKETVQGC :::::::::::::::::::::::::::::::::::::::: . ::.: NP_631 IVVFSLLAALLLAVGLALLVRKLREKRQTEGTYRPSSEEQVG----ARVPPTPNLKLPPE 70 80 90 100 110 pF1KE2 LPI NP_631 ERLI 120 123 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 03:33:54 2016 done: Tue Nov 8 03:33:55 2016 Total Scan time: 3.910 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]