FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2538, 2564 aa 1>>>pF1KE2538 2564 - 2564 aa - 2564 aa Library: /omim/omim.rfq.tfa 61265892 residues in 86068 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.3840+/-0.000507; mu= -16.6004+/- 0.032 mean_var=475.4244+/-101.481, 0's: 0 Z-trim(121.1): 181 B-trim: 2267 in 2/56 Lambda= 0.058821 statistics sampled from 37278 (37472) to 37278 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.716), E-opt: 0.2 (0.435), width: 16 Scan time: 20.810 The best scores are: opt bits E(86068) NP_054878 (OMIM: 612778,616831) histone-lysine N-m (2564) 17186 1474.9 0 XP_011531934 (OMIM: 612778,616831) PREDICTED: hist (2572) 17160 1472.7 0 XP_011531933 (OMIM: 612778,616831) PREDICTED: hist (2590) 17008 1459.8 0 XP_011531936 (OMIM: 612778,616831) PREDICTED: hist (2520) 16869 1448.0 0 XP_011531935 (OMIM: 612778,616831) PREDICTED: hist (2545) 11364 980.9 0 XP_016861759 (OMIM: 612778,616831) PREDICTED: hist (2490) 10343 894.2 0 XP_016864076 (OMIM: 194190,602952) PREDICTED: hist ( 584) 706 76.1 1.6e-12 XP_016864077 (OMIM: 194190,602952) PREDICTED: hist ( 584) 706 76.1 1.6e-12 XP_011511862 (OMIM: 194190,602952) PREDICTED: hist ( 584) 706 76.1 1.6e-12 XP_005248059 (OMIM: 194190,602952) PREDICTED: hist (1296) 706 76.3 3.1e-12 NP_579878 (OMIM: 194190,602952) histone-lysine N-m (1365) 706 76.3 3.3e-12 NP_001035889 (OMIM: 194190,602952) histone-lysine (1365) 706 76.3 3.3e-12 NP_579877 (OMIM: 194190,602952) histone-lysine N-m (1365) 706 76.3 3.3e-12 XP_005248058 (OMIM: 194190,602952) PREDICTED: hist (1365) 706 76.3 3.3e-12 NP_579890 (OMIM: 194190,602952) histone-lysine N-m (1365) 706 76.3 3.3e-12 XP_011511859 (OMIM: 194190,602952) PREDICTED: hist (1365) 706 76.3 3.3e-12 NP_075447 (OMIM: 607083) histone-lysine N-methyltr (1437) 672 73.4 2.5e-11 NP_758859 (OMIM: 117550,130650,606681) histone-lys (2427) 660 72.5 8e-11 XP_016857277 (OMIM: 607999) PREDICTED: histone-lys (1244) 649 71.4 8.7e-11 XP_011508072 (OMIM: 607999) PREDICTED: histone-lys (1244) 649 71.4 8.7e-11 NP_071900 (OMIM: 117550,130650,606681) histone-lys (2696) 660 72.5 8.7e-11 XP_006711515 (OMIM: 607999) PREDICTED: histone-lys (2904) 659 72.5 9.9e-11 XP_016857275 (OMIM: 607999) PREDICTED: histone-lys (2663) 649 71.6 1.7e-10 XP_006711513 (OMIM: 607999) PREDICTED: histone-lys (2964) 649 71.6 1.8e-10 NP_060959 (OMIM: 607999) histone-lysine N-methyltr (2964) 649 71.6 1.8e-10 XP_016857273 (OMIM: 607999) PREDICTED: histone-lys (2964) 649 71.6 1.8e-10 XP_016857274 (OMIM: 607999) PREDICTED: histone-lys (2964) 649 71.6 1.8e-10 XP_006711514 (OMIM: 607999) PREDICTED: histone-lys (2964) 649 71.6 1.8e-10 XP_011517333 (OMIM: 607001,610253) PREDICTED: hist ( 488) 351 45.9 0.0016 XP_011517332 (OMIM: 607001,610253) PREDICTED: hist ( 559) 351 46.0 0.0018 XP_011517331 (OMIM: 607001,610253) PREDICTED: hist ( 775) 351 46.0 0.0024 XP_011517335 (OMIM: 607001,610253) PREDICTED: hist (1246) 351 46.1 0.0036 XP_011517328 (OMIM: 607001,610253) PREDICTED: hist (1253) 351 46.1 0.0036 XP_016870627 (OMIM: 607001,610253) PREDICTED: hist (1260) 351 46.1 0.0036 XP_016870626 (OMIM: 607001,610253) PREDICTED: hist (1260) 351 46.1 0.0036 XP_016870625 (OMIM: 607001,610253) PREDICTED: hist (1265) 351 46.1 0.0036 XP_011517327 (OMIM: 607001,610253) PREDICTED: hist (1267) 351 46.1 0.0036 XP_005266167 (OMIM: 607001,610253) PREDICTED: hist (1267) 351 46.1 0.0036 XP_011517326 (OMIM: 607001,610253) PREDICTED: hist (1275) 351 46.1 0.0036 XP_016870624 (OMIM: 607001,610253) PREDICTED: hist (1291) 351 46.1 0.0037 XP_006717351 (OMIM: 607001,610253) PREDICTED: hist (1292) 351 46.1 0.0037 XP_016870623 (OMIM: 607001,610253) PREDICTED: hist (1293) 351 46.1 0.0037 XP_011517325 (OMIM: 607001,610253) PREDICTED: hist (1294) 351 46.1 0.0037 XP_005266162 (OMIM: 607001,610253) PREDICTED: hist (1295) 351 46.1 0.0037 NP_079033 (OMIM: 607001,610253) histone-lysine N-m (1298) 351 46.1 0.0037 XP_011517324 (OMIM: 607001,610253) PREDICTED: hist (1300) 351 46.1 0.0037 XP_011517323 (OMIM: 607001,610253) PREDICTED: hist (1301) 351 46.1 0.0037 NP_078946 (OMIM: 606503) histone-lysine N-methyltr ( 350) 331 44.2 0.0039 NP_001180354 (OMIM: 606503) histone-lysine N-methy ( 350) 331 44.2 0.0039 XP_006717566 (OMIM: 606503) PREDICTED: histone-lys ( 350) 331 44.2 0.0039 >>NP_054878 (OMIM: 612778,616831) histone-lysine N-methy (2564 aa) initn: 17186 init1: 17186 opt: 17186 Z-score: 7894.3 bits: 1474.9 E(86068): 0 Smith-Waterman score: 17186; 100.0% identity (100.0% similar) in 2564 aa overlap (1-2564:1-2564) 10 20 30 40 50 60 pF1KE2 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 GDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 TTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 PPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 SCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 EDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 EDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 RSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 RSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSY 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 RDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 RDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFR 490 500 510 520 530 540 550 560 570 580 590 600 pF1KE2 RGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 RGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KE2 RMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 RMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKN 610 620 630 640 650 660 670 680 690 700 710 720 pF1KE2 DQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 DQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KE2 FQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 FQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVD 730 740 750 760 770 780 790 800 810 820 830 840 pF1KE2 TRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRN 790 800 810 820 830 840 850 860 870 880 890 900 pF1KE2 LTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 LTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKC 850 860 870 880 890 900 910 920 930 940 950 960 pF1KE2 GENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQ 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KE2 EAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 EAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KE2 CDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 CDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPM 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KE2 EETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 EETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKN 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KE2 PEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQE 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KE2 ELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 ELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGW 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KE2 DFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 DFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVY 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KE2 DRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 DRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDT 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KE2 LAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 LAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KE2 GSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCE 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KE2 CTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 CTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKK 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KE2 GWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQK 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KE2 GNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFC 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KE2 GSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSR 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KE2 LMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 LMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEI 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KE2 IKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 IKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDP 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KE2 STKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 STKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEE 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KE2 EELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 EELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPS 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KE2 QDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 QDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTER 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KE2 GRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 GRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYD 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KE2 TPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAP 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KE2 HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 HHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAP 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KE2 PPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSV 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KE2 SVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 SVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAH 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KE2 PQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARD 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 2460 pF1KE2 PEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEA 2410 2420 2430 2440 2450 2460 2470 2480 2490 2500 2510 2520 pF1KE2 DTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 DTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKE 2470 2480 2490 2500 2510 2520 2530 2540 2550 2560 pF1KE2 LKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE :::::::::::::::::::::::::::::::::::::::::::: NP_054 LKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE 2530 2540 2550 2560 >>XP_011531934 (OMIM: 612778,616831) PREDICTED: histone- (2572 aa) initn: 17172 init1: 16997 opt: 17160 Z-score: 7882.3 bits: 1472.7 E(86068): 0 Smith-Waterman score: 17160; 99.7% identity (99.7% similar) in 2572 aa overlap (1-2564:1-2572) 10 20 30 40 50 pF1KE2 MKQLQPQPPPKMGDFYDPEHPTPE--------EEENEAKIENVQKTGFIKGPMFKGVASS :::::::::::::::::::::::: :::::::::::::::::::::::::::: XP_011 MKQLQPQPPPKMGDFYDPEHPTPEFSWLNGNREEENEAKIENVQKTGFIKGPMFKGVASS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE2 TPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAP 130 140 150 160 170 180 180 190 200 210 220 230 pF1KE2 LPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVD 190 200 210 220 230 240 240 250 260 270 280 290 pF1KE2 VAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEI 250 260 270 280 290 300 300 310 320 330 340 350 pF1KE2 PDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KE2 KSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERG 370 380 390 400 410 420 420 430 440 450 460 470 pF1KE2 SRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRR 430 440 450 460 470 480 480 490 500 510 520 530 pF1KE2 TSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCS 490 500 510 520 530 540 540 550 560 570 580 590 pF1KE2 PPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQT 550 560 570 580 590 600 600 610 620 630 640 650 pF1KE2 PCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKEL 610 620 630 640 650 660 660 670 680 690 700 710 pF1KE2 DSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVK 670 680 690 700 710 720 720 730 740 750 760 770 pF1KE2 ACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KE2 TVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESK 790 800 810 820 830 840 840 850 860 870 880 890 pF1KE2 PVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKV 850 860 870 880 890 900 900 910 920 930 940 950 pF1KE2 DSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNN 910 920 930 940 950 960 960 970 980 990 1000 1010 pF1KE2 GLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDS 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KE2 DGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVV 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KE2 PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFF 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KE2 LHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKA 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KE2 KIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSS 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KE2 EELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGR 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KE2 PPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEI 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KE2 SSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVE 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KE2 QGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHR 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KE2 DIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADV 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KE2 EVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKND 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KE2 EIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYG 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KE2 KEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDK 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KE2 NQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRES 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KE2 NQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAH 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KE2 TPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQL 1870 1880 1890 1900 1910 1920 1920 1930 1940 1950 1960 1970 pF1KE2 ENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEE 1930 1940 1950 1960 1970 1980 1980 1990 2000 2010 2020 2030 pF1KE2 PINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTE 1990 2000 2010 2020 2030 2040 2040 2050 2060 2070 2080 2090 pF1KE2 KENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGT 2050 2060 2070 2080 2090 2100 2100 2110 2120 2130 2140 2150 pF1KE2 KRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPY 2110 2120 2130 2140 2150 2160 2160 2170 2180 2190 2200 2210 pF1KE2 DSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGH 2170 2180 2190 2200 2210 2220 2220 2230 2240 2250 2260 2270 pF1KE2 STEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSV 2230 2240 2250 2260 2270 2280 2280 2290 2300 2310 2320 2330 pF1KE2 WDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQ 2290 2300 2310 2320 2330 2340 2340 2350 2360 2370 2380 2390 pF1KE2 GQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLP 2350 2360 2370 2380 2390 2400 2400 2410 2420 2430 2440 2450 pF1KE2 PNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKAS 2410 2420 2430 2440 2450 2460 2460 2470 2480 2490 2500 2510 pF1KE2 KKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKL 2470 2480 2490 2500 2510 2520 2520 2530 2540 2550 2560 pF1KE2 THGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 THGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE 2530 2540 2550 2560 2570 >>XP_011531933 (OMIM: 612778,616831) PREDICTED: histone- (2590 aa) initn: 17008 init1: 17008 opt: 17008 Z-score: 7812.6 bits: 1459.8 E(86068): 0 Smith-Waterman score: 17008; 99.8% identity (99.9% similar) in 2545 aa overlap (20-2564:46-2590) 10 20 30 40 pF1KE2 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGV .: .::::::::::::::::::::::::: XP_011 LLLASFCLTPYIQEAELFEGRDAALFKFGLQPLAQEEENEAKIENVQKTGFIKGPMFKGV 20 30 40 50 60 70 50 60 70 80 90 100 pF1KE2 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ 80 90 100 110 120 130 110 120 130 140 150 160 pF1KE2 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH 140 150 160 170 180 190 170 180 190 200 210 220 pF1KE2 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL 200 210 220 230 240 250 230 240 250 260 270 280 pF1KE2 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD 260 270 280 290 300 310 290 300 310 320 330 340 pF1KE2 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER 320 330 340 350 360 370 350 360 370 380 390 400 pF1KE2 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS 380 390 400 410 420 430 410 420 430 440 450 460 pF1KE2 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY 440 450 460 470 480 490 470 480 490 500 510 520 pF1KE2 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR 500 510 520 530 540 550 530 540 550 560 570 580 pF1KE2 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS 560 570 580 590 600 610 590 600 610 620 630 640 pF1KE2 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI 620 630 640 650 660 670 650 660 670 680 690 700 pF1KE2 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP 680 690 700 710 720 730 710 720 730 740 750 760 pF1KE2 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD 740 750 760 770 780 790 770 780 790 800 810 820 pF1KE2 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL 800 810 820 830 840 850 830 840 850 860 870 880 pF1KE2 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG 860 870 880 890 900 910 890 900 910 920 930 940 pF1KE2 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR 920 930 940 950 960 970 950 960 970 980 990 1000 pF1KE2 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM 980 990 1000 1010 1020 1030 1010 1020 1030 1040 1050 1060 pF1KE2 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV 1040 1050 1060 1070 1080 1090 1070 1080 1090 1100 1110 1120 pF1KE2 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD 1100 1110 1120 1130 1140 1150 1130 1140 1150 1160 1170 1180 pF1KE2 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET 1160 1170 1180 1190 1200 1210 1190 1200 1210 1220 1230 1240 pF1KE2 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL 1220 1230 1240 1250 1260 1270 1250 1260 1270 1280 1290 1300 pF1KE2 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR 1280 1290 1300 1310 1320 1330 1310 1320 1330 1340 1350 1360 pF1KE2 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA 1340 1350 1360 1370 1380 1390 1370 1380 1390 1400 1410 1420 pF1KE2 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV 1400 1410 1420 1430 1440 1450 1430 1440 1450 1460 1470 1480 pF1KE2 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK 1460 1470 1480 1490 1500 1510 1490 1500 1510 1520 1530 1540 pF1KE2 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH 1520 1530 1540 1550 1560 1570 1550 1560 1570 1580 1590 1600 pF1KE2 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL 1580 1590 1600 1610 1620 1630 1610 1620 1630 1640 1650 1660 pF1KE2 KNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQ 1640 1650 1660 1670 1680 1690 1670 1680 1690 1700 1710 1720 pF1KE2 RYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGL 1700 1710 1720 1730 1740 1750 1730 1740 1750 1760 1770 1780 pF1KE2 SDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDG 1760 1770 1780 1790 1800 1810 1790 1800 1810 1820 1830 1840 pF1KE2 RESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTS 1820 1830 1840 1850 1860 1870 1850 1860 1870 1880 1890 1900 pF1KE2 RAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDL 1880 1890 1900 1910 1920 1930 1910 1920 1930 1940 1950 1960 pF1KE2 DQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTK 1940 1950 1960 1970 1980 1990 1970 1980 1990 2000 2010 2020 pF1KE2 LEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKS 2000 2010 2020 2030 2040 2050 2030 2040 2050 2060 2070 2080 pF1KE2 QTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYE 2060 2070 2080 2090 2100 2110 2090 2100 2110 2120 2130 2140 pF1KE2 RGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSP 2120 2130 2140 2150 2160 2170 2150 2160 2170 2180 2190 2200 pF1KE2 LPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPL 2180 2190 2200 2210 2220 2230 2210 2220 2230 2240 2250 2260 pF1KE2 VGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQN 2240 2250 2260 2270 2280 2290 2270 2280 2290 2300 2310 2320 pF1KE2 YSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQ 2300 2310 2320 2330 2340 2350 2330 2340 2350 2360 2370 2380 pF1KE2 YIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTI 2360 2370 2380 2390 2400 2410 2390 2400 2410 2420 2430 2440 pF1KE2 VLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPM 2420 2430 2440 2450 2460 2470 2450 2460 2470 2480 2490 2500 pF1KE2 KASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLA 2480 2490 2500 2510 2520 2530 2510 2520 2530 2540 2550 2560 pF1KE2 RKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE 2540 2550 2560 2570 2580 2590 >>XP_011531936 (OMIM: 612778,616831) PREDICTED: histone- (2520 aa) initn: 16869 init1: 16869 opt: 16869 Z-score: 7749.0 bits: 1448.0 E(86068): 0 Smith-Waterman score: 16869; 100.0% identity (100.0% similar) in 2520 aa overlap (45-2564:1-2520) 20 30 40 50 60 70 pF1KE2 FYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGVASSRFLPKGTKTKVNLEEQGRQKVS :::::::::::::::::::::::::::::: XP_011 MFKGVASSRFLPKGTKTKVNLEEQGRQKVS 10 20 30 80 90 100 110 120 130 pF1KE2 FSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQVDSTPKMKMEIGDTLSTAEESSPPK 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE2 SRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAESTTVDSPPSSPPPPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTHAAPLPAVIAESTTVDSPPSSPPPPP 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE2 PPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPLPVDVAVRSLKEPPIIIVPESLEADT 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE2 KQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KQDTISNSLEEHVTQILNEQADISSKKEDSHIGKDEEIPDSSKISLSCKKTGSKKKSSQS 220 230 240 250 260 270 320 330 340 350 360 370 pF1KE2 EGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKERDFKKSSAPLKSEDLGKPSRSKTDRD 280 290 300 310 320 330 380 390 400 410 420 430 pF1KE2 DKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRSERGSRTNLSYSRSERSHYYDSDRRY 340 350 360 370 380 390 440 450 460 470 480 490 pF1KE2 HRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTYSRRTSSHSSSYRDLRTSSYSKSDRD 400 410 420 430 440 450 500 510 520 530 540 550 pF1KE2 CKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGSSYSKHDSSASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CKTETSYLEMERRGKYSSKLERESKRTSENEAIKRCCSPPNELGFRRGSSYSKHDSSASR 460 470 480 490 500 510 560 570 580 590 600 610 pF1KE2 YKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFSLQTPCSKGSELRMINKNPEREKAGS 520 530 540 550 560 570 620 630 640 650 660 670 pF1KE2 PAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSIKELDSLSKVKNDQLRSFCPIELNIN 580 590 600 610 620 630 680 690 700 710 720 730 pF1KE2 GSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGFQNISRCKEKDLDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSPLVKACMLSSNGFQNISRCKEKDLDD 640 650 660 670 680 690 740 750 760 770 780 790 pF1KE2 TCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVDYSKTVVKEPVDTRVSCCKTKDSDIY 700 710 720 730 740 750 800 810 820 830 840 850 pF1KE2 CTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHLESKPVICDSRNLTDHSKFACEEYKQ 760 770 780 790 800 810 860 870 880 890 900 910 pF1KE2 SIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKCGENTSPVLDAVLKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPGIKVDSLTLLKCGENTSPVLDAVLKS 820 830 840 850 860 870 920 930 940 950 960 970 pF1KE2 KKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENRRNNGLSGKCLQEAQEEGNSILPERR 880 890 900 910 920 930 980 990 1000 1010 1020 1030 pF1KE2 GRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTMEDSDGVTYALKCDSSGHAPEIVSTV 940 950 960 970 980 990 1040 1050 1060 1070 1080 1090 pF1KE2 HEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSVVVVPKNSTLPMEETSPCSSRSSQSY 1000 1010 1020 1030 1040 1050 1100 1110 1120 1130 1140 1150 pF1KE2 RHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RHYSDHWEDERLESRRHLYEEKFESIASKACPQTDKFFLHKGTEKNPEISFTQSSRKQID 1060 1070 1080 1090 1100 1110 1160 1170 1180 1190 1200 1210 pF1KE2 NRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEETVKAKIPSRQQEELPIYSSDFEDVPN 1120 1130 1140 1150 1160 1170 1220 1230 1240 1250 1260 1270 pF1KE2 KSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGWDFSQEKPSTTYQQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGLHSSEELRNLGWDFSQEKPSTTYQQP 1180 1190 1200 1210 1220 1230 1280 1290 1300 1310 1320 1330 pF1KE2 DSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPRSGRPPGTGVVYDRTQGQVPDSLTDD 1240 1250 1260 1270 1280 1290 1340 1350 1360 1370 1380 1390 pF1KE2 REEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQAPEISSNSIKDTLAVNEKKDFSKNLE 1300 1310 1320 1330 1340 1350 1400 1410 1420 1430 1440 1450 pF1KE2 KNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPPGSALVGPSCVMDDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRVEVEQGETSVPPGSALVGPSCVMDDF 1360 1370 1380 1390 1400 1410 1460 1470 1480 1490 1500 1510 pF1KE2 RDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRMQCECTPLSKDERAQGEI 1420 1430 1440 1450 1460 1470 1520 1530 1540 1550 1560 1570 pF1KE2 ACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNT 1480 1490 1500 1510 1520 1530 1580 1590 1600 1610 1620 1630 pF1KE2 FVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPN 1540 1550 1560 1570 1580 1590 1640 1650 1660 1670 1680 1690 pF1KE2 CETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENR 1600 1610 1620 1630 1640 1650 1700 1710 1720 1730 1740 1750 pF1KE2 VSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSIRAAGGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTC 1660 1670 1680 1690 1700 1710 1760 1770 1780 1790 1800 1810 pF1KE2 LELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNM 1720 1730 1740 1750 1760 1770 1820 1830 1840 1850 1860 1870 pF1KE2 LEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPK 1780 1790 1800 1810 1820 1830 1880 1890 1900 1910 1920 1930 pF1KE2 KLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLMFRRLKIISENSMDSAISDATSELEGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLP 1840 1850 1860 1870 1880 1890 1940 1950 1960 1970 1980 1990 pF1KE2 ECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ECKVDSETNIEASKLPTSEPEADAEIEPKESNGTKLEEPINEETPSQDEEEGVSDVESER 1900 1910 1920 1930 1940 1950 2000 2010 2020 2030 2040 2050 pF1KE2 SQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAP 1960 1970 1980 1990 2000 2010 2060 2070 2080 2090 2100 2110 pF1KE2 KTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRPDDRYDTPTSKKKVRIKDRN 2020 2030 2040 2050 2060 2070 2120 2130 2140 2150 2160 2170 pF1KE2 KLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQ 2080 2090 2100 2110 2120 2130 2180 2190 2200 2210 2220 2230 pF1KE2 AYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAAPVE 2140 2150 2160 2170 2180 2190 2240 2250 2260 2270 2280 2290 pF1KE2 VSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQNYSVWDSNQQSVSVQQQYSPAQSQAT 2200 2210 2220 2230 2240 2250 2300 2310 2320 2330 2340 2350 pF1KE2 IYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQIFTAHPQGVVVQPAAAVTT 2260 2270 2280 2290 2300 2310 2360 2370 2380 2390 2400 2410 pF1KE2 IVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNWKTARDPEGKIYYYHVITRQ 2320 2330 2340 2350 2360 2370 2420 2430 2440 2450 2460 2470 pF1KE2 TQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPMKASKKPKTAEADTSSELAKKSKEVF 2380 2390 2400 2410 2420 2430 2480 2490 2500 2510 2520 2530 pF1KE2 RKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLARKLTHGVMNKELKYCKNPEDLECNE 2440 2450 2460 2470 2480 2490 2540 2550 2560 pF1KE2 NVKHKTKEYIKKYMQKFGAVYKPKEDTELE :::::::::::::::::::::::::::::: XP_011 NVKHKTKEYIKKYMQKFGAVYKPKEDTELE 2500 2510 2520 >>XP_011531935 (OMIM: 612778,616831) PREDICTED: histone- (2545 aa) initn: 16719 init1: 11313 opt: 11364 Z-score: 5224.2 bits: 980.9 E(86068): 0 Smith-Waterman score: 16633; 98.1% identity (98.2% similar) in 2545 aa overlap (20-2564:46-2545) 10 20 30 40 pF1KE2 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGV .: .::::::::::::::::::::::::: XP_011 LLLASFCLTPYIQEAELFEGRDAALFKFGLQPLAQEEENEAKIENVQKTGFIKGPMFKGV 20 30 40 50 60 70 50 60 70 80 90 100 pF1KE2 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ 80 90 100 110 120 130 110 120 130 140 150 160 pF1KE2 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH 140 150 160 170 180 190 170 180 190 200 210 220 pF1KE2 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL 200 210 220 230 240 250 230 240 250 260 270 280 pF1KE2 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD 260 270 280 290 300 310 290 300 310 320 330 340 pF1KE2 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER 320 330 340 350 360 370 350 360 370 380 390 400 pF1KE2 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS 380 390 400 410 420 430 410 420 430 440 450 460 pF1KE2 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY 440 450 460 470 480 490 470 480 490 500 510 520 pF1KE2 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR 500 510 520 530 540 550 530 540 550 560 570 580 pF1KE2 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS 560 570 580 590 600 610 590 600 610 620 630 640 pF1KE2 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI 620 630 640 650 660 670 650 660 670 680 690 700 pF1KE2 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP 680 690 700 710 720 730 710 720 730 740 750 760 pF1KE2 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD 740 750 760 770 780 790 770 780 790 800 810 820 pF1KE2 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL 800 810 820 830 840 850 830 840 850 860 870 880 pF1KE2 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG 860 870 880 890 900 910 890 900 910 920 930 940 pF1KE2 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR 920 930 940 950 960 970 950 960 970 980 990 1000 pF1KE2 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM 980 990 1000 1010 1020 1030 1010 1020 1030 1040 1050 1060 pF1KE2 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV 1040 1050 1060 1070 1080 1090 1070 1080 1090 1100 1110 1120 pF1KE2 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD 1100 1110 1120 1130 1140 1150 1130 1140 1150 1160 1170 1180 pF1KE2 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET 1160 1170 1180 1190 1200 1210 1190 1200 1210 1220 1230 1240 pF1KE2 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL 1220 1230 1240 1250 1260 1270 1250 1260 1270 1280 1290 1300 pF1KE2 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR 1280 1290 1300 1310 1320 1330 1310 1320 1330 1340 1350 1360 pF1KE2 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA 1340 1350 1360 1370 1380 1390 1370 1380 1390 1400 1410 1420 pF1KE2 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV 1400 1410 1420 1430 1440 1450 1430 1440 1450 1460 1470 1480 pF1KE2 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK 1460 1470 1480 1490 1500 1510 1490 1500 1510 1520 1530 1540 pF1KE2 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH 1520 1530 1540 1550 1560 1570 1550 1560 1570 1580 1590 1600 pF1KE2 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL 1580 1590 1600 1610 1620 1630 1610 1620 1630 1640 1650 1660 pF1KE2 KNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQ 1640 1650 1660 1670 1680 1690 1670 1680 1690 1700 1710 1720 pF1KE2 RYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGL ::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDS--------------- 1700 1710 1720 1730 1740 1730 1740 1750 1760 1770 1780 pF1KE2 SDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDG :::::::::::::::::::::::::::::: XP_011 ------------------------------NTHSQSCLKSFLERHGLSLLWIWMAELGDG 1750 1760 1770 1790 1800 1810 1820 1830 1840 pF1KE2 RESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTS 1780 1790 1800 1810 1820 1830 1850 1860 1870 1880 1890 1900 pF1KE2 RAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDL 1840 1850 1860 1870 1880 1890 1910 1920 1930 1940 1950 1960 pF1KE2 DQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTK 1900 1910 1920 1930 1940 1950 1970 1980 1990 2000 2010 2020 pF1KE2 LEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKS 1960 1970 1980 1990 2000 2010 2030 2040 2050 2060 2070 2080 pF1KE2 QTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYE 2020 2030 2040 2050 2060 2070 2090 2100 2110 2120 2130 2140 pF1KE2 RGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSP 2080 2090 2100 2110 2120 2130 2150 2160 2170 2180 2190 2200 pF1KE2 LPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPL 2140 2150 2160 2170 2180 2190 2210 2220 2230 2240 2250 2260 pF1KE2 VGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQN 2200 2210 2220 2230 2240 2250 2270 2280 2290 2300 2310 2320 pF1KE2 YSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQ 2260 2270 2280 2290 2300 2310 2330 2340 2350 2360 2370 2380 pF1KE2 YIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTI 2320 2330 2340 2350 2360 2370 2390 2400 2410 2420 2430 2440 pF1KE2 VLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPM 2380 2390 2400 2410 2420 2430 2450 2460 2470 2480 2490 2500 pF1KE2 KASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLA 2440 2450 2460 2470 2480 2490 2510 2520 2530 2540 2550 2560 pF1KE2 RKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE 2500 2510 2520 2530 2540 >>XP_016861759 (OMIM: 612778,616831) PREDICTED: histone- (2490 aa) initn: 10341 init1: 10341 opt: 10343 Z-score: 4756.1 bits: 894.2 E(86068): 0 Smith-Waterman score: 16103; 95.9% identity (96.0% similar) in 2545 aa overlap (20-2564:46-2490) 10 20 30 40 pF1KE2 MKQLQPQPPPKMGDFYDPEHPTPEEEENEAKIENVQKTGFIKGPMFKGV .: .::::::::::::::::::::::::: XP_016 LLLASFCLTPYIQEAELFEGRDAALFKFGLQPLAQEEENEAKIENVQKTGFIKGPMFKGV 20 30 40 50 60 70 50 60 70 80 90 100 pF1KE2 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASSRFLPKGTKTKVNLEEQGRQKVSFSFSLTKKTLQNRFLTALGNEKQSDTPNPPAVPLQ 80 90 100 110 120 130 110 120 130 140 150 160 pF1KE2 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDSTPKMKMEIGDTLSTAEESSPPKSRVELGKIHFKKHLLHVTSRPLLATTTAVASPPTH 140 150 160 170 180 190 170 180 190 200 210 220 pF1KE2 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAPLPAVIAESTTVDSPPSSPPPPPPPAQATTLSSPAPVTEPVALPHTPITVLMAAPVPL 200 210 220 230 240 250 230 240 250 260 270 280 pF1KE2 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVDVAVRSLKEPPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD 260 270 280 290 300 310 290 300 310 320 330 340 pF1KE2 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEIPDSSKISLSCKKTGSKKKSSQSEGIFLGSESDEDSVRTSSSQRSHDLKFSASIEKER 320 330 340 350 360 370 350 360 370 380 390 400 pF1KE2 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DFKKSSAPLKSEDLGKPSRSKTDRDDKYFSYSKLERDTRYVSSRCRSERERRRSRSHSRS 380 390 400 410 420 430 410 420 430 440 450 460 pF1KE2 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERGSRTNLSYSRSERSHYYDSDRRYHRSSPYRERTRYSRPYTDNRARESSDSEEEYKKTY 440 450 460 470 480 490 470 480 490 500 510 520 pF1KE2 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SRRTSSHSSSYRDLRTSSYSKSDRDCKTETSYLEMERRGKYSSKLERESKRTSENEAIKR 500 510 520 530 540 550 530 540 550 560 570 580 pF1KE2 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CCSPPNELGFRRGSSYSKHDSSASRYKSTLSKPIPKSDKFKNSFCCTELNEEIKQSHSFS 560 570 580 590 600 610 590 600 610 620 630 640 pF1KE2 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQTPCSKGSELRMINKNPEREKAGSPAPSNRLNDSPTLKKLDELPIFKSEFITHDSHDSI 620 630 640 650 660 670 650 660 670 680 690 700 pF1KE2 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KELDSLSKVKNDQLRSFCPIELNINGSPGAESDLATFCTSKTDAVLMTSDDSVTGSELSP 680 690 700 710 720 730 710 720 730 740 750 760 pF1KE2 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVKACMLSSNGFQNISRCKEKDLDDTCMLHKKSESPFRETEPLVSPHQDKLMSMPVMTVD 740 750 760 770 780 790 770 780 790 800 810 820 pF1KE2 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSKTVVKEPVDTRVSCCKTKDSDIYCTLNDSNPSLCNSEAENIEPSVMKISSNSFMNVHL 800 810 820 830 840 850 830 840 850 860 870 880 pF1KE2 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKPVICDSRNLTDHSKFACEEYKQSIGSTSSASVNHFDDLYQPIGSSGIASSLQSLPPG 860 870 880 890 900 910 890 900 910 920 930 940 pF1KE2 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKVDSLTLLKCGENTSPVLDAVLKSKKSSEFLKHAGKETIVEVGSDLPDSGKGFASRENR 920 930 940 950 960 970 950 960 970 980 990 1000 pF1KE2 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RNNGLSGKCLQEAQEEGNSILPERRGRPEISLDERGEGGHVHTSDDSEVVFSSCDLNLTM 980 990 1000 1010 1020 1030 1010 1020 1030 1040 1050 1060 pF1KE2 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDSDGVTYALKCDSSGHAPEIVSTVHEDYSGSSESSNDESDSEDTDSDDSSIPRNRLQSV 1040 1050 1060 1070 1080 1090 1070 1080 1090 1100 1110 1120 pF1KE2 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVVPKNSTLPMEETSPCSSRSSQSYRHYSDHWEDERLESRRHLYEEKFESIASKACPQTD 1100 1110 1120 1130 1140 1150 1130 1140 1150 1160 1170 1180 pF1KE2 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KFFLHKGTEKNPEISFTQSSRKQIDNRLPELSHPQSDGVDSTSHTDVKSDPLGHPNSEET 1160 1170 1180 1190 1200 1210 1190 1200 1210 1220 1230 1240 pF1KE2 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKAKIPSRQQEELPIYSSDFEDVPNKSWQQTTFQNRPDSRLGKTELSFSSSCEIPHVDGL 1220 1230 1240 1250 1260 1270 1250 1260 1270 1280 1290 1300 pF1KE2 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSSEELRNLGWDFSQEKPSTTYQQPDSSYGACGGHKYQQNAEQYGGTRDYWQGNGYWDPR 1280 1290 1300 1310 1320 1330 1310 1320 1330 1340 1350 1360 pF1KE2 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGRPPGTGVVYDRTQGQVPDSLTDDREEEENWDQQDGSHFSDQSDKFLLSLQKDKGSVQA 1340 1350 1360 1370 1380 1390 1370 1380 1390 1400 1410 1420 pF1KE2 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEISSNSIKDTLAVNEKKDFSKNLEKNDIKDRGPLKKRRQEIESDSESDGELQDRKKVRV 1400 1410 1420 1430 1440 1450 1430 1440 1450 1460 1470 1480 pF1KE2 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVEQGETSVPPGSALVGPSCVMDDFRDPQRWKECAKQGKMPCYFDLIEENVYLTERKKNK 1460 1470 1480 1490 1500 1510 1490 1500 1510 1520 1530 1540 pF1KE2 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHRDIKRMQCECTPLSKDERAQGEIACGEDCLNRLLMIECSSRCPNGDYCSNRRFQRKQH 1520 1530 1540 1550 1560 1570 1550 1560 1570 1580 1590 1600 pF1KE2 ADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKNIHYYFMAL ::::::::::::::::::::::: XP_016 ADVEVILTEKKGWGLRAAKDLPS------------------------------------- 1580 1590 1610 1620 1630 1640 1650 1660 pF1KE2 KNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSELTFDYQFQ XP_016 ------------------------------------------------------------ 1670 1680 1690 1700 1710 1720 pF1KE2 RYGKEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ---KEAQKCFCGSANCRGYLGGENRVSIRAAGGKMKKERSRKKDSVDGELEALMENGEGL 1600 1610 1620 1630 1640 1650 1730 1740 1750 1760 1770 1780 pF1KE2 SDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDKNQVLSLSRLMVRIETLEQKLTCLELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDG 1660 1670 1680 1690 1700 1710 1790 1800 1810 1820 1830 1840 pF1KE2 RESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RESNQKLQEEIIKTLEHLPIPTKNMLEESKVLPIIQRWSQTKTAVPPLSEGDGYSSENTS 1720 1730 1740 1750 1760 1770 1850 1860 1870 1880 1890 1900 pF1KE2 RAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAISDATSELEGKDGKEDL 1780 1790 1800 1810 1820 1830 1910 1920 1930 1940 1950 1960 pF1KE2 DQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADAEIEPKESNGTK 1840 1850 1860 1870 1880 1890 1970 1980 1990 2000 2010 2020 pF1KE2 LEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEEPINEETPSQDEEEGVSDVESERSQEQPDKTVDISDLATKLLDSWKDLKEVYRIPKKS 1900 1910 1920 1930 1940 1950 2030 2040 2050 2060 2070 2080 pF1KE2 QTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYE 1960 1970 1980 1990 2000 2010 2090 2100 2110 2120 2130 2140 pF1KE2 RGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGTKRPDDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSP 2020 2030 2040 2050 2060 2070 2150 2160 2170 2180 2190 2200 pF1KE2 LPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPYDSLGYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPL 2080 2090 2100 2110 2120 2130 2210 2220 2230 2240 2250 2260 pF1KE2 VGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGHSTEPLSAPPPVPVVPHVAAPVEVSSSQYVAQSDGVVHQDSSVAVLPVPAPGPVQGQN 2140 2150 2160 2170 2180 2190 2270 2280 2290 2300 2310 2320 pF1KE2 YSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSVWDSNQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQ 2200 2210 2220 2230 2240 2250 2330 2340 2350 2360 2370 2380 pF1KE2 YIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIQGQQIFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTI 2260 2270 2280 2290 2300 2310 2390 2400 2410 2420 2430 2440 pF1KE2 VLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLPPNWKTARDPEGKIYYYHVITRQTQWDPPTWESPGDDASLEHEAEMDLGTPTYDENPM 2320 2330 2340 2350 2360 2370 2450 2460 2470 2480 2490 2500 pF1KE2 KASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KASKKPKTAEADTSSELAKKSKEVFRKEMSQFIVQCLNPYRKPDCKVGRITTTEDFKHLA 2380 2390 2400 2410 2420 2430 2510 2520 2530 2540 2550 2560 pF1KE2 RKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKLTHGVMNKELKYCKNPEDLECNENVKHKTKEYIKKYMQKFGAVYKPKEDTELE 2440 2450 2460 2470 2480 2490 >>XP_016864076 (OMIM: 194190,602952) PREDICTED: histone- (584 aa) initn: 703 init1: 604 opt: 706 Z-score: 345.9 bits: 76.1 E(86068): 1.6e-12 Smith-Waterman score: 706; 40.3% identity (69.2% similar) in 273 aa overlap (1493-1757:228-489) 1470 1480 1490 1500 1510 pF1KE2 CAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRM-QCECTPLSKDERAQGEIACGED-- ::... .:.: : ... :: : XP_016 RETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENP-------CGFDSE 200 210 220 230 240 250 1520 1530 1540 1550 1560 1570 pF1KE2 CLNRLLMIECSSR-CPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLE ::::.::.:: . :: :..:.:. : ..:. ....: :. ::::: : .:. .. :: : XP_016 CLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNE 260 270 280 290 300 310 1580 1590 1600 1610 1620 1630 pF1KE2 YCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQ : ::..:..: ::.:. .: :.:.... .:.:::: ::: ::::::::.::::: XP_016 YVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETL 320 330 340 350 360 370 1640 1650 1660 1670 1680 1690 pF1KE2 KWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR ::::::. :::.:.. .:.:.::::.:... :.: : ::..:: :.:: . ..: XP_016 KWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTT 380 390 400 410 420 430 1700 1710 1720 1730 1740 1750 pF1KE2 AA----GGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTC . : : ::. :.. . .:. .. : . .: .:.. .: .. : .:.: XP_016 LSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFR-CGDGGQLVLCDR---KFCTKAYHLSC 440 450 460 470 480 1760 1770 1780 1790 1800 1810 pF1KE2 LELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNM : : XP_016 LGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHD 490 500 510 520 530 540 >>XP_016864077 (OMIM: 194190,602952) PREDICTED: histone- (584 aa) initn: 703 init1: 604 opt: 706 Z-score: 345.9 bits: 76.1 E(86068): 1.6e-12 Smith-Waterman score: 706; 40.3% identity (69.2% similar) in 273 aa overlap (1493-1757:228-489) 1470 1480 1490 1500 1510 pF1KE2 CAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRM-QCECTPLSKDERAQGEIACGED-- ::... .:.: : ... :: : XP_016 RETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENP-------CGFDSE 200 210 220 230 240 250 1520 1530 1540 1550 1560 1570 pF1KE2 CLNRLLMIECSSR-CPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLE ::::.::.:: . :: :..:.:. : ..:. ....: :. ::::: : .:. .. :: : XP_016 CLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNE 260 270 280 290 300 310 1580 1590 1600 1610 1620 1630 pF1KE2 YCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQ : ::..:..: ::.:. .: :.:.... .:.:::: ::: ::::::::.::::: XP_016 YVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETL 320 330 340 350 360 370 1640 1650 1660 1670 1680 1690 pF1KE2 KWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR ::::::. :::.:.. .:.:.::::.:... :.: : ::..:: :.:: . ..: XP_016 KWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTT 380 390 400 410 420 430 1700 1710 1720 1730 1740 1750 pF1KE2 AA----GGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTC . : : ::. :.. . .:. .. : . .: .:.. .: .. : .:.: XP_016 LSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFR-CGDGGQLVLCDR---KFCTKAYHLSC 440 450 460 470 480 1760 1770 1780 1790 1800 1810 pF1KE2 LELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNM : : XP_016 LGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHD 490 500 510 520 530 540 >>XP_011511862 (OMIM: 194190,602952) PREDICTED: histone- (584 aa) initn: 703 init1: 604 opt: 706 Z-score: 345.9 bits: 76.1 E(86068): 1.6e-12 Smith-Waterman score: 706; 40.3% identity (69.2% similar) in 273 aa overlap (1493-1757:228-489) 1470 1480 1490 1500 1510 pF1KE2 CAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRM-QCECTPLSKDERAQGEIACGED-- ::... .:.: : ... :: : XP_011 RETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENP-------CGFDSE 200 210 220 230 240 250 1520 1530 1540 1550 1560 1570 pF1KE2 CLNRLLMIECSSR-CPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLE ::::.::.:: . :: :..:.:. : ..:. ....: :. ::::: : .:. .. :: : XP_011 CLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNE 260 270 280 290 300 310 1580 1590 1600 1610 1620 1630 pF1KE2 YCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQ : ::..:..: ::.:. .: :.:.... .:.:::: ::: ::::::::.::::: XP_011 YVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETL 320 330 340 350 360 370 1640 1650 1660 1670 1680 1690 pF1KE2 KWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR ::::::. :::.:.. .:.:.::::.:... :.: : ::..:: :.:: . ..: XP_011 KWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTT 380 390 400 410 420 430 1700 1710 1720 1730 1740 1750 pF1KE2 AA----GGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTC . : : ::. :.. . .:. .. : . .: .:.. .: .. : .:.: XP_011 LSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFR-CGDGGQLVLCDR---KFCTKAYHLSC 440 450 460 470 480 1760 1770 1780 1790 1800 1810 pF1KE2 LELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNM : : XP_011 LGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHD 490 500 510 520 530 540 >>XP_005248059 (OMIM: 194190,602952) PREDICTED: histone- (1296 aa) initn: 703 init1: 604 opt: 706 Z-score: 340.6 bits: 76.3 E(86068): 3.1e-12 Smith-Waterman score: 706; 40.3% identity (69.2% similar) in 273 aa overlap (1493-1757:940-1201) 1470 1480 1490 1500 1510 pF1KE2 CAKQGKMPCYFDLIEENVYLTERKKNKSHRDIKRM-QCECTPLSKDERAQGEIACGED-- ::... .:.: : ... :: : XP_005 RETQESERKPPPYKHIKVNKPYGKVQIYTADISEIPKCNCKPTDENP-------CGFDSE 910 920 930 940 950 960 1520 1530 1540 1550 1560 1570 pF1KE2 CLNRLLMIECSSR-CPNGDYCSNRRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLE ::::.::.:: . :: :..:.:. : ..:. ....: :. ::::: : .:. .. :: : XP_005 CLNRMLMFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTDGKGWGLVAKRDIRKGEFVNE 970 980 990 1000 1010 1020 1580 1590 1600 1610 1620 1630 pF1KE2 YCGEVLDHKEFKARVKEYARNKNIHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQ : ::..:..: ::.:. .: :.:.... .:.:::: ::: ::::::::.::::: XP_005 YVGELIDEEECMARIKHAHENDITHFYMLTIDKDRIIDAGPKGNYSRFMNHSCQPNCETL 1030 1040 1050 1060 1070 1080 1640 1650 1660 1670 1680 1690 pF1KE2 KWTVNGQLRVGFFTTKLVPSGSELTFDYQFQRYGKEAQKCFCGSANCRGYLGGENRVSIR ::::::. :::.:.. .:.:.::::.:... :.: : ::..:: :.:: . ..: XP_005 KWTVNGDTRVGLFAVCDIPAGTELTFNYNLDCLGNEKTVCRCGASNCSGFLGDRPKTSTT 1090 1100 1110 1120 1130 1140 1700 1710 1720 1730 1740 1750 pF1KE2 AA----GGKMKKERSRKKDSVDGELEALMENGEGLSDKNQVLSLSRLMVRIETLEQKLTC . : : ::. :.. . .:. .. : . .: .:.. .: .. : .:.: XP_005 LSSEEKGKKTKKKTRRRRAKGEGKRQSEDECFR-CGDGGQLVLCDR---KFCTKAYHLSC 1150 1160 1170 1180 1190 1760 1770 1780 1790 1800 1810 pF1KE2 LELIQNTHSQSCLKSFLERHGLSLLWIWMAELGDGRESNQKLQEEIIKTLEHLPIPTKNM : : XP_005 LGLGKRPFGKWECPWHHCDVCGKPSTSFCHLCPNSFCKEHQDGTAFSCTPDGRSYCCEHD 1200 1210 1220 1230 1240 1250 2564 residues in 1 query sequences 61265892 residues in 86068 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Feb 10 15:00:53 2017 done: Fri Feb 10 15:00:56 2017 Total Scan time: 20.810 Total Display time: 1.350 Function used was FASTA [36.3.4 Apr, 2011]