FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2554, 361 aa 1>>>pF1KE2554 361 - 361 aa - 361 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8802+/-0.000841; mu= 15.1014+/- 0.051 mean_var=96.1537+/-18.887, 0's: 0 Z-trim(109.9): 114 B-trim: 294 in 1/50 Lambda= 0.130795 statistics sampled from 11130 (11251) to 11130 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.346), width: 16 Scan time: 1.780 The best scores are: opt bits E(32554) CCDS4804.1 PPARD gene_id:5467|Hs108|chr6 ( 361) 2426 467.8 6.6e-132 CCDS4803.1 PPARD gene_id:5467|Hs108|chr6 ( 441) 2412 465.2 4.8e-131 CCDS54994.1 PPARD gene_id:5467|Hs108|chr6 ( 402) 2129 411.7 5.3e-115 CCDS33669.1 PPARA gene_id:5465|Hs108|chr22 ( 468) 1466 286.7 2.7e-77 CCDS54995.1 PPARD gene_id:5467|Hs108|chr6 ( 343) 1417 277.3 1.3e-74 CCDS2610.2 PPARG gene_id:5468|Hs108|chr3 ( 477) 1342 263.3 3.1e-70 CCDS2609.1 PPARG gene_id:5468|Hs108|chr3 ( 505) 1342 263.3 3.2e-70 CCDS33718.1 NR1D2 gene_id:9975|Hs108|chr3 ( 579) 462 97.3 3.5e-20 CCDS11361.1 NR1D1 gene_id:9572|Hs108|chr17 ( 614) 449 94.9 2e-19 CCDS8850.1 RARG gene_id:5916|Hs108|chr12 ( 454) 392 84.0 2.7e-16 CCDS6646.1 RORB gene_id:6096|Hs108|chr9 ( 459) 391 83.8 3.1e-16 CCDS58236.1 RARG gene_id:5916|Hs108|chr12 ( 382) 389 83.4 3.5e-16 CCDS41790.1 RARG gene_id:5916|Hs108|chr12 ( 443) 389 83.4 4e-16 CCDS11366.1 RARA gene_id:5914|Hs108|chr17 ( 462) 387 83.1 5.3e-16 CCDS5063.1 NR2E1 gene_id:7101|Hs108|chr6 ( 385) 384 82.5 6.8e-16 CCDS2642.1 RARB gene_id:5915|Hs108|chr3 ( 448) 381 81.9 1.1e-15 CCDS42317.1 RARA gene_id:5914|Hs108|chr17 ( 457) 381 81.9 1.2e-15 CCDS69165.1 NR2E1 gene_id:7101|Hs108|chr6 ( 422) 380 81.7 1.2e-15 CCDS30856.1 RORC gene_id:6097|Hs108|chr1 ( 497) 377 81.2 2.1e-15 CCDS1004.1 RORC gene_id:6097|Hs108|chr1 ( 518) 377 81.2 2.1e-15 CCDS10375.1 NR2F2 gene_id:7026|Hs108|chr15 ( 414) 374 80.6 2.7e-15 CCDS42593.1 NR1H2 gene_id:7376|Hs108|chr19 ( 460) 373 80.4 3.3e-15 CCDS12352.1 NR2F6 gene_id:2063|Hs108|chr19 ( 404) 369 79.6 5e-15 CCDS45271.1 RORA gene_id:6095|Hs108|chr15 ( 468) 369 79.7 5.6e-15 CCDS10177.1 RORA gene_id:6095|Hs108|chr15 ( 523) 369 79.7 6.1e-15 CCDS10178.1 RORA gene_id:6095|Hs108|chr15 ( 548) 369 79.7 6.4e-15 CCDS10179.1 RORA gene_id:6095|Hs108|chr15 ( 556) 369 79.7 6.4e-15 CCDS4068.1 NR2F1 gene_id:7025|Hs108|chr5 ( 423) 363 78.5 1.1e-14 CCDS4768.1 RXRB gene_id:6257|Hs108|chr6 ( 533) 364 78.8 1.2e-14 CCDS59007.1 RXRB gene_id:6257|Hs108|chr6 ( 537) 364 78.8 1.2e-14 CCDS35172.1 RXRA gene_id:6256|Hs108|chr9 ( 462) 356 77.2 3.1e-14 CCDS1248.1 RXRG gene_id:6258|Hs108|chr1 ( 463) 353 76.7 4.5e-14 CCDS73751.1 NR2E3 gene_id:10002|Hs108|chr15 ( 367) 350 76.0 5.6e-14 CCDS73750.1 NR2E3 gene_id:10002|Hs108|chr15 ( 410) 350 76.1 6.1e-14 CCDS72970.1 RXRG gene_id:6258|Hs108|chr1 ( 340) 345 75.1 1e-13 CCDS8818.1 NR4A1 gene_id:3164|Hs108|chr12 ( 598) 339 74.1 3.4e-13 CCDS55828.1 NR4A1 gene_id:3164|Hs108|chr12 ( 611) 339 74.1 3.5e-13 CCDS73471.1 NR4A1 gene_id:3164|Hs108|chr12 ( 652) 339 74.1 3.7e-13 CCDS6744.1 NR4A3 gene_id:8013|Hs108|chr9 ( 443) 334 73.1 5.3e-13 CCDS41821.1 NR2C1 gene_id:7181|Hs108|chr12 ( 467) 334 73.1 5.5e-13 CCDS44953.1 NR2C1 gene_id:7181|Hs108|chr12 ( 483) 334 73.1 5.6e-13 CCDS55340.1 NR6A1 gene_id:2649|Hs108|chr9 ( 475) 333 72.9 6.3e-13 CCDS65127.1 NR6A1 gene_id:2649|Hs108|chr9 ( 476) 333 72.9 6.3e-13 CCDS9051.1 NR2C1 gene_id:7181|Hs108|chr12 ( 603) 334 73.2 6.7e-13 CCDS6743.1 NR4A3 gene_id:8013|Hs108|chr9 ( 626) 334 73.2 6.9e-13 CCDS6742.1 NR4A3 gene_id:8013|Hs108|chr9 ( 637) 334 73.2 7e-13 CCDS2201.1 NR4A2 gene_id:4929|Hs108|chr2 ( 598) 333 73.0 7.6e-13 CCDS35137.1 NR6A1 gene_id:2649|Hs108|chr9 ( 480) 331 72.5 8.3e-13 CCDS6856.1 NR5A1 gene_id:2516|Hs108|chr9 ( 461) 325 71.4 1.8e-12 CCDS74905.1 NR2C2 gene_id:7182|Hs108|chr3 ( 596) 324 71.3 2.4e-12 >>CCDS4804.1 PPARD gene_id:5467|Hs108|chr6 (361 aa) initn: 2426 init1: 2426 opt: 2426 Z-score: 2481.6 bits: 467.8 E(32554): 6.6e-132 Smith-Waterman score: 2426; 100.0% identity (100.0% similar) in 361 aa overlap (1-361:1-361) 10 20 30 40 50 60 pF1KE2 MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGG 310 320 330 340 350 360 pF1KE2 E : CCDS48 E >>CCDS4803.1 PPARD gene_id:5467|Hs108|chr6 (441 aa) initn: 2412 init1: 2412 opt: 2412 Z-score: 2466.1 bits: 465.2 E(32554): 4.8e-131 Smith-Waterman score: 2412; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KE2 MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD 310 320 330 340 350 360 pF1KE2 E CCDS48 RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI 370 380 390 400 410 420 >>CCDS54994.1 PPARD gene_id:5467|Hs108|chr6 (402 aa) initn: 2129 init1: 2129 opt: 2129 Z-score: 2178.1 bits: 411.7 E(32554): 5.3e-115 Smith-Waterman score: 2129; 100.0% identity (100.0% similar) in 316 aa overlap (44-359:5-320) 20 30 40 50 60 70 pF1KE2 EEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNME :::::::::::::::::::::::::::::: CCDS54 MHQRDLSRSSSPPSLLDQLQMGCDGASCGSLNME 10 20 30 80 90 100 110 120 130 pF1KE2 CRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 CRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKC 40 50 60 70 80 90 140 150 160 170 180 190 pF1KE2 LALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMT 100 110 120 130 140 150 200 210 220 230 240 250 pF1KE2 KKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTT 160 170 180 190 200 210 260 270 280 290 300 310 pF1KE2 VETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVT 220 230 240 250 260 270 320 330 340 350 360 pF1KE2 REFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGGE :::::::::::::::::::::::::::::::::::::::::::::: CCDS54 REFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAI 280 290 300 310 320 330 CCDS54 QDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLL 340 350 360 370 380 390 >>CCDS33669.1 PPARA gene_id:5465|Hs108|chr22 (468 aa) initn: 1446 init1: 841 opt: 1466 Z-score: 1501.0 bits: 286.7 E(32554): 2.7e-77 Smith-Waterman score: 1466; 68.6% identity (86.6% similar) in 322 aa overlap (40-359:66-386) 10 20 30 40 50 60 pF1KE2 EVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTD-LSRSSSPPSLLDQLQMGC-DGASC : :: :: .::: :. . : : . CCDS33 EISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPS 40 50 60 70 80 90 70 80 90 100 110 120 pF1KE2 GSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQY :.::.:::.:::::::.:::::::::::::::::::.:: :.::.::::::::::::::: CCDS33 GALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQY 100 110 120 130 140 150 130 140 150 160 170 180 pF1KE2 CRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYL :::.:::..:::::::::::::..:: :: : . . : . . ..::::...:.::.::: CCDS33 CRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYL 160 170 180 190 200 210 190 200 210 220 230 240 pF1KE2 KNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFY :::::.: ::: ::.::::.. ::::::.::: .::: :: : ..::. :: :..:. CCDS33 KNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQN-KEAEVRIFH 220 230 240 250 260 270 250 260 270 280 290 300 pF1KE2 RCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVAN ::::.:::: :::::::.::.:..: ::::::::::::.:::::::.:..::::.::: CCDS33 CCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAY 280 290 300 310 320 330 310 320 330 340 350 360 pF1KE2 GSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGGE :.::.:::::.:::::: ::.::::.::.:::::::::::..::.:::: :: CCDS33 GNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNV 340 350 360 370 380 390 CCDS33 GHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDA 400 410 420 430 440 450 >>CCDS54995.1 PPARD gene_id:5467|Hs108|chr6 (343 aa) initn: 1417 init1: 1417 opt: 1417 Z-score: 1452.9 bits: 277.3 E(32554): 1.3e-74 Smith-Waterman score: 1487; 72.7% identity (72.7% similar) in 359 aa overlap (1-359:1-261) 10 20 30 40 50 60 pF1KE2 MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQM ::::::::::::::::::::::::::::::::::::::::::: CCDS54 MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYT----------------- 10 20 30 40 70 80 90 100 110 120 pF1KE2 GCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKK CCDS54 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KE2 NRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK ::::::::::::::::::::::::::::::::::::::: CCDS54 ---------------------AIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSK 50 60 70 80 190 200 210 220 230 240 pF1KE2 HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKE 90 100 110 120 130 140 250 260 270 280 290 300 pF1KE2 ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNK 150 160 170 180 190 200 310 320 330 340 350 360 pF1KE2 DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 DGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGD 210 220 230 240 250 260 pF1KE2 E CCDS54 RPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRI 270 280 290 300 310 320 >>CCDS2610.2 PPARG gene_id:5468|Hs108|chr3 (477 aa) initn: 1324 init1: 781 opt: 1342 Z-score: 1374.5 bits: 263.3 E(32554): 3.1e-70 Smith-Waterman score: 1342; 61.5% identity (86.3% similar) in 314 aa overlap (49-359:83-395) 20 30 40 50 60 70 pF1KE2 EVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGC---DGASCGSLNMECR .::: .. :. . : . . .::: CCDS26 IPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECR 60 70 80 90 100 110 80 90 100 110 120 130 pF1KE2 VCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLA ::::::::::::::::::::::::::::.:: :..:. .:.:.::.:::::::::::::: CCDS26 VCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLA 120 130 140 150 160 170 140 150 160 170 180 190 pF1KE2 LGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKK .:::::::::::::.:::.::.: .... .: ::. :::.:..::.:..:.:.: .:: CCDS26 VGMSHNAIRFGRMPQAEKEKLLAEISSDI-DQLNPESADLRALAKHLYDSYIKSFPLTKA 180 190 200 210 220 230 200 210 220 230 240 250 pF1KE2 KARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVE :::.:::::.. .::::.:...: ..: . .:... ::.....: :: .:: CCDS26 KARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVE 240 250 260 270 280 290 260 270 280 290 300 310 pF1KE2 TVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTRE .:.:.::.:::::.: .: :::::::::::::: :..::::..::::.:...:.::.::: CCDS26 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTRE 300 310 320 330 340 350 320 330 340 350 360 pF1KE2 FLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGGE ::.::::::.:..:::::::::::::::::::::.:::.::: : CCDS26 FLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQD 360 370 380 390 400 410 CCDS26 NLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQE 420 430 440 450 460 470 >>CCDS2609.1 PPARG gene_id:5468|Hs108|chr3 (505 aa) initn: 1324 init1: 781 opt: 1342 Z-score: 1374.1 bits: 263.3 E(32554): 3.2e-70 Smith-Waterman score: 1342; 61.5% identity (86.3% similar) in 314 aa overlap (49-359:111-423) 20 30 40 50 60 70 pF1KE2 EVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGC---DGASCGSLNMECR .::: .. :. . : . . .::: CCDS26 IPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECR 90 100 110 120 130 140 80 90 100 110 120 130 pF1KE2 VCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLA ::::::::::::::::::::::::::::.:: :..:. .:.:.::.:::::::::::::: CCDS26 VCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLA 150 160 170 180 190 200 140 150 160 170 180 190 pF1KE2 LGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKK .:::::::::::::.:::.::.: .... .: ::. :::.:..::.:..:.:.: .:: CCDS26 VGMSHNAIRFGRMPQAEKEKLLAEISSDI-DQLNPESADLRALAKHLYDSYIKSFPLTKA 210 220 230 240 250 200 210 220 230 240 250 pF1KE2 KARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVE :::.:::::.. .::::.:...: ..: . .:... ::.....: :: .:: CCDS26 KARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVE 260 270 280 290 300 310 260 270 280 290 300 310 pF1KE2 TVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTRE .:.:.::.:::::.: .: :::::::::::::: :..::::..::::.:...:.::.::: CCDS26 AVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTRE 320 330 340 350 360 370 320 330 340 350 360 pF1KE2 FLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGGE ::.::::::.:..:::::::::::::::::::::.:::.::: : CCDS26 FLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQD 380 390 400 410 420 430 CCDS26 NLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQE 440 450 460 470 480 490 >>CCDS33718.1 NR1D2 gene_id:9975|Hs108|chr3 (579 aa) initn: 589 init1: 228 opt: 462 Z-score: 475.9 bits: 97.3 E(32554): 3.5e-20 Smith-Waterman score: 462; 45.8% identity (73.6% similar) in 144 aa overlap (46-187:79-212) 20 30 40 50 60 70 pF1KE2 EKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECR :.::.: . . . : : .. . :. CCDS33 SDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPG--MTKSHSGVTKFS--GMVLLCK 50 60 70 80 90 100 80 90 100 110 120 130 pF1KE2 VCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERS--CKIQKKNRNKCQYCRFQKC :::: ::::::::::::::::::::.:.....:.:: .. :.:.. :::.:: :::.:: CCDS33 VCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKC 110 120 130 140 150 160 140 150 160 170 180 190 pF1KE2 LALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMT :..:::..:.::::.:. ::.... . . ...: : :: :. : : CCDS33 LSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ------FSGHLQNDTLVEHHEQ 170 180 190 200 210 200 210 220 230 240 250 pF1KE2 KKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTT CCDS33 TALPAQEQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAES 220 230 240 250 260 270 >>CCDS11361.1 NR1D1 gene_id:9572|Hs108|chr17 (614 aa) initn: 573 init1: 241 opt: 449 Z-score: 462.3 bits: 94.9 E(32554): 2e-19 Smith-Waterman score: 455; 46.1% identity (78.0% similar) in 141 aa overlap (30-158:78-218) 10 20 30 40 50 pF1KE2 MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLL---- .:.:. . ::: .. ..:::. : CCDS11 CPTYFPPSPTGSLTQDPARSFGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAM 50 60 70 80 90 100 60 70 80 90 100 pF1KE2 -DQLQMGCDGASCG--SLN---MECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYE :. ... . .. . .:: . :.:::: ::::::::::::::::::::.:.....:. CCDS11 EDSSRVSPSKSTSNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYK 110 120 130 140 150 160 110 120 130 140 150 160 pF1KE2 KCERS--CKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQ .: .. :.: . :::.:: :::.:::..:::..:.::::.:. ::....: CCDS11 RCLKNENCSIVRINRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLA 170 180 190 200 210 220 170 180 190 200 210 220 pF1KE2 YNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLV CCDS11 NNQLSSQCPLETSPTQHPTPGPMGPSPPPAPVPSPLVGFSQFPQQLTPPRSPSPEPTVED 230 240 250 260 270 280 >>CCDS8850.1 RARG gene_id:5916|Hs108|chr12 (454 aa) initn: 463 init1: 179 opt: 392 Z-score: 406.0 bits: 84.0 E(32554): 2.7e-16 Smith-Waterman score: 465; 28.7% identity (59.2% similar) in 338 aa overlap (26-359:43-339) 10 20 30 40 50 pF1KE2 MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLL .: . : : ::. ...:: .. : CCDS88 ALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKE-MASLSVETQSTSSE 20 30 40 50 60 70 60 70 80 90 100 110 pF1KE2 DQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCER-- ... . . . : ::.::.::.:::: .::::::::::.:. .. : :.: CCDS88 EMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYT-CHRDK 80 90 100 110 120 130 120 130 140 150 160 170 pF1KE2 SCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVA .: :.: .::.:::::.:::. .:::..:.: : .:.: : . .. . .::. CCDS88 NCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDR---NKKKKEVKEEGSPDSYELSPQLE 140 150 160 170 180 180 190 200 210 220 230 pF1KE2 DLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVN .: ..: . .:. ..: . .. ...:.: . : . :: : . CCDS88 EL--ITK-VSKAHQETFPSLCQLGKYTTNSSADHRV-----------QLDLGL-WDK--- 190 200 210 220 240 250 260 270 280 290 pF1KE2 GLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAM ..:... .: . ...:::: .:.:..: . ::.:::: . . .. CCDS88 ----FSELAT----KC-------IIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLR 230 240 250 260 270 300 310 320 330 340 350 pF1KE2 LAS--IVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALF . . ..: . ..: . .. . :..:.. : :: .. ::.::.. .:. CCDS88 ICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLV---FAFAGQLLPLEMDDTETGLL 280 290 300 310 320 330 360 pF1KE2 IAAIILCGGE : ..:: CCDS88 SAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRGIST 340 350 360 370 380 390 361 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 10:48:47 2016 done: Tue Nov 8 10:48:48 2016 Total Scan time: 1.780 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]