Result of FASTA (omim) for
pF1KE2556
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2556, 1174 aa
1>>>pF1KE2556 1174 - 1174 aa - 1174 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2379+/-0.000428; mu= -0.2353+/- 0.027
mean_var=253.8584+/-52.755, 0's: 0 Z-trim(119.9): 647 B-trim: 1184 in 1/51
Lambda= 0.080497
statistics sampled from 33824 (34486) to 33824 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.404), width: 16
Scan time: 14.940
The best scores are: opt bits E(85289)
XP_011534669 (OMIM: 603271) PREDICTED: tyrosine-pr (1174) 7908 932.5 0
NP_008970 (OMIM: 603271) tyrosine-protein phosphat (1174) 7908 932.5 0
XP_005267344 (OMIM: 603271) PREDICTED: tyrosine-pr (1174) 7908 932.5 0
XP_006720074 (OMIM: 603271) PREDICTED: tyrosine-pr (1051) 6947 820.9 0
XP_016876427 (OMIM: 603271) PREDICTED: tyrosine-pr (1051) 6947 820.9 0
XP_011534670 (OMIM: 603271) PREDICTED: tyrosine-pr (1051) 6947 820.9 0
XP_016876428 (OMIM: 603271) PREDICTED: tyrosine-pr ( 970) 6576 777.8 0
XP_011534671 (OMIM: 603271) PREDICTED: tyrosine-pr ( 970) 6576 777.8 0
NP_005392 (OMIM: 603155,613611) tyrosine-protein p (1187) 2539 309.0 1.1e-82
XP_016857430 (OMIM: 603155,613611) PREDICTED: tyro (1187) 2539 309.0 1.1e-82
NP_002824 (OMIM: 600768) tyrosine-protein phosphat ( 593) 589 82.4 9.4e-15
XP_016881130 (OMIM: 605331) PREDICTED: band 4.1-li ( 820) 565 79.7 8.5e-14
XP_016881127 (OMIM: 605331) PREDICTED: band 4.1-li ( 830) 565 79.7 8.6e-14
XP_016881135 (OMIM: 605331) PREDICTED: band 4.1-li ( 838) 565 79.7 8.6e-14
XP_016881123 (OMIM: 605331) PREDICTED: band 4.1-li ( 842) 565 79.7 8.7e-14
XP_016881124 (OMIM: 605331) PREDICTED: band 4.1-li ( 842) 565 79.7 8.7e-14
XP_011523939 (OMIM: 605331) PREDICTED: band 4.1-li ( 847) 565 79.7 8.7e-14
XP_016881132 (OMIM: 605331) PREDICTED: band 4.1-li ( 850) 565 79.7 8.7e-14
XP_016881120 (OMIM: 605331) PREDICTED: band 4.1-li ( 853) 565 79.7 8.8e-14
NP_001268463 (OMIM: 605331) band 4.1-like protein ( 865) 565 79.7 8.9e-14
XP_016881129 (OMIM: 605331) PREDICTED: band 4.1-li ( 869) 565 79.7 8.9e-14
XP_016881115 (OMIM: 605331) PREDICTED: band 4.1-li ( 871) 565 79.7 8.9e-14
XP_016881113 (OMIM: 605331) PREDICTED: band 4.1-li ( 875) 565 79.7 8.9e-14
XP_016881126 (OMIM: 605331) PREDICTED: band 4.1-li ( 877) 565 79.7 9e-14
XP_016881112 (OMIM: 605331) PREDICTED: band 4.1-li ( 879) 565 79.7 9e-14
XP_011523936 (OMIM: 605331) PREDICTED: band 4.1-li ( 881) 565 79.7 9e-14
XP_016881125 (OMIM: 605331) PREDICTED: band 4.1-li ( 883) 565 79.7 9e-14
NP_001268462 (OMIM: 605331) band 4.1-like protein ( 883) 565 79.7 9e-14
XP_016881110 (OMIM: 605331) PREDICTED: band 4.1-li ( 888) 565 79.7 9e-14
XP_016881109 (OMIM: 605331) PREDICTED: band 4.1-li ( 890) 565 79.7 9.1e-14
XP_016881122 (OMIM: 605331) PREDICTED: band 4.1-li ( 891) 565 79.7 9.1e-14
XP_016881121 (OMIM: 605331) PREDICTED: band 4.1-li ( 891) 565 79.7 9.1e-14
XP_016881108 (OMIM: 605331) PREDICTED: band 4.1-li ( 896) 565 79.7 9.1e-14
XP_011523934 (OMIM: 605331) PREDICTED: band 4.1-li ( 902) 565 79.7 9.2e-14
XP_016881107 (OMIM: 605331) PREDICTED: band 4.1-li ( 904) 565 79.7 9.2e-14
XP_016881117 (OMIM: 605331) PREDICTED: band 4.1-li ( 906) 565 79.7 9.2e-14
XP_016881116 (OMIM: 605331) PREDICTED: band 4.1-li ( 916) 565 79.7 9.3e-14
XP_016881114 (OMIM: 605331) PREDICTED: band 4.1-li ( 918) 565 79.7 9.3e-14
NP_001317486 (OMIM: 605331) band 4.1-like protein ( 918) 565 79.7 9.3e-14
XP_011523928 (OMIM: 605331) PREDICTED: band 4.1-li ( 931) 565 79.7 9.4e-14
XP_011523925 (OMIM: 605331) PREDICTED: band 4.1-li ( 943) 565 79.7 9.5e-14
XP_016881133 (OMIM: 605331) PREDICTED: band 4.1-li ( 847) 561 79.2 1.2e-13
XP_016881131 (OMIM: 605331) PREDICTED: band 4.1-li ( 865) 561 79.2 1.2e-13
XP_016881128 (OMIM: 605331) PREDICTED: band 4.1-li ( 873) 561 79.2 1.2e-13
XP_016881119 (OMIM: 605331) PREDICTED: band 4.1-li ( 900) 561 79.2 1.3e-13
XP_016881118 (OMIM: 605331) PREDICTED: band 4.1-li ( 900) 561 79.2 1.3e-13
XP_016881111 (OMIM: 605331) PREDICTED: band 4.1-li ( 925) 561 79.2 1.3e-13
NP_976217 (OMIM: 130500,611804) protein 4.1 isofor ( 641) 556 78.6 1.4e-13
NP_036439 (OMIM: 605331) band 4.1-like protein 3 i (1087) 561 79.3 1.5e-13
XP_005245820 (OMIM: 130500,611804) PREDICTED: prot ( 850) 557 78.8 1.7e-13
>>XP_011534669 (OMIM: 603271) PREDICTED: tyrosine-protei (1174 aa)
initn: 7908 init1: 7908 opt: 7908 Z-score: 4975.1 bits: 932.5 E(85289): 0
Smith-Waterman score: 7908; 100.0% identity (100.0% similar) in 1174 aa overlap (1-1174:1-1174)
10 20 30 40 50 60
pF1KE2 MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 HKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 YAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSVP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRVH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 HSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 AAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDFE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 AEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEY
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 ERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 SGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 VTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 LEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KE2 DMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
::::::::::::::::::::::::::::::::::
XP_011 DMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
1150 1160 1170
>>NP_008970 (OMIM: 603271) tyrosine-protein phosphatase (1174 aa)
initn: 7908 init1: 7908 opt: 7908 Z-score: 4975.1 bits: 932.5 E(85289): 0
Smith-Waterman score: 7908; 100.0% identity (100.0% similar) in 1174 aa overlap (1-1174:1-1174)
10 20 30 40 50 60
pF1KE2 MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 HKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 HKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 NLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 YAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 YAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSVP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRVH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 HSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 HSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 AAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDFE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 EESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 AEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 KTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEY
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 ERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 SGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 VTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 VTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 LEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KE2 DMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
::::::::::::::::::::::::::::::::::
NP_008 DMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
1150 1160 1170
>>XP_005267344 (OMIM: 603271) PREDICTED: tyrosine-protei (1174 aa)
initn: 7908 init1: 7908 opt: 7908 Z-score: 4975.1 bits: 932.5 E(85289): 0
Smith-Waterman score: 7908; 100.0% identity (100.0% similar) in 1174 aa overlap (1-1174:1-1174)
10 20 30 40 50 60
pF1KE2 MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 HKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 NLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNPS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 ITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGSS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 YAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSVP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 ELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRVH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 HSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSAS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 AAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDFE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 EESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRTT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 AEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMK
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 KTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEY
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 ERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 SGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNT
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 VTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSY
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 LEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVL
1090 1100 1110 1120 1130 1140
1150 1160 1170
pF1KE2 DMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
::::::::::::::::::::::::::::::::::
XP_005 DMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
1150 1160 1170
>>XP_006720074 (OMIM: 603271) PREDICTED: tyrosine-protei (1051 aa)
initn: 6947 init1: 6947 opt: 6947 Z-score: 4372.7 bits: 820.9 E(85289): 0
Smith-Waterman score: 6947; 100.0% identity (100.0% similar) in 1025 aa overlap (150-1174:27-1051)
120 130 140 150 160 170
pF1KE2 YYLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEK
::::::::::::::::::::::::::::::
XP_006 MHWNLPSILEWCFMCLQFLSCSRRLPADFGDFDQYESQDFLQKFALFPVGWLQDEK
10 20 30 40 50
180 190 200 210 220 230
pF1KE2 VLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLE
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE2 GIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVA
120 130 140 150 160 170
300 310 320 330 340 350
pF1KE2 RHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQ
180 190 200 210 220 230
360 370 380 390 400 410
pF1KE2 DNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNP
240 250 260 270 280 290
420 430 440 450 460 470
pF1KE2 SITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGS
300 310 320 330 340 350
480 490 500 510 520 530
pF1KE2 SYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSV
360 370 380 390 400 410
540 550 560 570 580 590
pF1KE2 PELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRV
420 430 440 450 460 470
600 610 620 630 640 650
pF1KE2 HHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSA
480 490 500 510 520 530
660 670 680 690 700 710
pF1KE2 SAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDF
540 550 560 570 580 590
720 730 740 750 760 770
pF1KE2 EEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRT
600 610 620 630 640 650
780 790 800 810 820 830
pF1KE2 TAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGM
660 670 680 690 700 710
840 850 860 870 880 890
pF1KE2 KKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTE
720 730 740 750 760 770
900 910 920 930 940 950
pF1KE2 YERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVS
780 790 800 810 820 830
960 970 980 990 1000 1010
pF1KE2 VSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHN
840 850 860 870 880 890
1020 1030 1040 1050 1060 1070
pF1KE2 TVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLS
900 910 920 930 940 950
1080 1090 1100 1110 1120 1130
pF1KE2 YLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRV
960 970 980 990 1000 1010
1140 1150 1160 1170
pF1KE2 LDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
:::::::::::::::::::::::::::::::::::
XP_006 LDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
1020 1030 1040 1050
>>XP_016876427 (OMIM: 603271) PREDICTED: tyrosine-protei (1051 aa)
initn: 6947 init1: 6947 opt: 6947 Z-score: 4372.7 bits: 820.9 E(85289): 0
Smith-Waterman score: 6947; 100.0% identity (100.0% similar) in 1025 aa overlap (150-1174:27-1051)
120 130 140 150 160 170
pF1KE2 YYLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEK
::::::::::::::::::::::::::::::
XP_016 MHWNLPSILEWCFMCLQFLSCSRRLPADFGDFDQYESQDFLQKFALFPVGWLQDEK
10 20 30 40 50
180 190 200 210 220 230
pF1KE2 VLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLE
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE2 GIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVA
120 130 140 150 160 170
300 310 320 330 340 350
pF1KE2 RHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQ
180 190 200 210 220 230
360 370 380 390 400 410
pF1KE2 DNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNP
240 250 260 270 280 290
420 430 440 450 460 470
pF1KE2 SITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGS
300 310 320 330 340 350
480 490 500 510 520 530
pF1KE2 SYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSV
360 370 380 390 400 410
540 550 560 570 580 590
pF1KE2 PELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRV
420 430 440 450 460 470
600 610 620 630 640 650
pF1KE2 HHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSA
480 490 500 510 520 530
660 670 680 690 700 710
pF1KE2 SAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDF
540 550 560 570 580 590
720 730 740 750 760 770
pF1KE2 EEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRT
600 610 620 630 640 650
780 790 800 810 820 830
pF1KE2 TAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGM
660 670 680 690 700 710
840 850 860 870 880 890
pF1KE2 KKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTE
720 730 740 750 760 770
900 910 920 930 940 950
pF1KE2 YERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVS
780 790 800 810 820 830
960 970 980 990 1000 1010
pF1KE2 VSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHN
840 850 860 870 880 890
1020 1030 1040 1050 1060 1070
pF1KE2 TVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLS
900 910 920 930 940 950
1080 1090 1100 1110 1120 1130
pF1KE2 YLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRV
960 970 980 990 1000 1010
1140 1150 1160 1170
pF1KE2 LDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
:::::::::::::::::::::::::::::::::::
XP_016 LDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
1020 1030 1040 1050
>>XP_011534670 (OMIM: 603271) PREDICTED: tyrosine-protei (1051 aa)
initn: 6947 init1: 6947 opt: 6947 Z-score: 4372.7 bits: 820.9 E(85289): 0
Smith-Waterman score: 6947; 100.0% identity (100.0% similar) in 1025 aa overlap (150-1174:27-1051)
120 130 140 150 160 170
pF1KE2 YYLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEK
::::::::::::::::::::::::::::::
XP_011 MHWNLPSILEWCFMCLQFLSCSRRLPADFGDFDQYESQDFLQKFALFPVGWLQDEK
10 20 30 40 50
180 190 200 210 220 230
pF1KE2 VLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLE
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE2 GIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVA
120 130 140 150 160 170
300 310 320 330 340 350
pF1KE2 RHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEPYASSQ
180 190 200 210 220 230
360 370 380 390 400 410
pF1KE2 DNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSNP
240 250 260 270 280 290
420 430 440 450 460 470
pF1KE2 SITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIGS
300 310 320 330 340 350
480 490 500 510 520 530
pF1KE2 SYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVVGAVSV
360 370 380 390 400 410
540 550 560 570 580 590
pF1KE2 PELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDLITRRV
420 430 440 450 460 470
600 610 620 630 640 650
pF1KE2 HHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKERTLSA
480 490 500 510 520 530
660 670 680 690 700 710
pF1KE2 SAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEEEDEDF
540 550 560 570 580 590
720 730 740 750 760 770
pF1KE2 EEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDSSPVRT
600 610 620 630 640 650
780 790 800 810 820 830
pF1KE2 TAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGM
660 670 680 690 700 710
840 850 860 870 880 890
pF1KE2 KKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTE
720 730 740 750 760 770
900 910 920 930 940 950
pF1KE2 YERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVS
780 790 800 810 820 830
960 970 980 990 1000 1010
pF1KE2 VSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHN
840 850 860 870 880 890
1020 1030 1040 1050 1060 1070
pF1KE2 TVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLS
900 910 920 930 940 950
1080 1090 1100 1110 1120 1130
pF1KE2 YLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRV
960 970 980 990 1000 1010
1140 1150 1160 1170
pF1KE2 LDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
:::::::::::::::::::::::::::::::::::
XP_011 LDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
1020 1030 1040 1050
>>XP_016876428 (OMIM: 603271) PREDICTED: tyrosine-protei (970 aa)
initn: 6576 init1: 6576 opt: 6576 Z-score: 4140.3 bits: 777.8 E(85289): 0
Smith-Waterman score: 6576; 100.0% identity (100.0% similar) in 970 aa overlap (205-1174:1-970)
180 190 200 210 220 230
pF1KE2 LQDEKVLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISI
::::::::::::::::::::::::::::::
XP_016 MLYMQEVERMDGYGEESYPAKDSQGSDISI
10 20 30
240 250 260 270 280 290
pF1KE2 GACLEGIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GACLEGIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIW
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE2 RLCVARHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLCVARHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEP
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE2 YASSQDNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YASSQDNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSP
160 170 180 190 200 210
420 430 440 450 460 470
pF1KE2 MSSNPSITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSNPSITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRN
220 230 240 250 260 270
480 490 500 510 520 530
pF1KE2 LNIGSSYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNIGSSYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVV
280 290 300 310 320 330
540 550 560 570 580 590
pF1KE2 GAVSVPELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAVSVPELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KE2 ITRRVHHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITRRVHHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKE
400 410 420 430 440 450
660 670 680 690 700 710
pF1KE2 RTLSASAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTLSASAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEE
460 470 480 490 500 510
720 730 740 750 760 770
pF1KE2 EDEDFEEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEDFEEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDS
520 530 540 550 560 570
780 790 800 810 820 830
pF1KE2 SPVRTTAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPVRTTAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLP
580 590 600 610 620 630
840 850 860 870 880 890
pF1KE2 PLGGMKKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLGGMKKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQG
640 650 660 670 680 690
900 910 920 930 940 950
pF1KE2 MVFTEYERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVFTEYERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINAS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KE2 HIKVSVSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HIKVSVSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRL
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KE2 GSRHNTVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSRHNTVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDL
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KE2 KGFLSYLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGFLSYLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVL
880 890 900 910 920 930
1140 1150 1160 1170
pF1KE2 DIPRVLDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
::::::::::::::::::::::::::::::::::::::::
XP_016 DIPRVLDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
940 950 960 970
>>XP_011534671 (OMIM: 603271) PREDICTED: tyrosine-protei (970 aa)
initn: 6576 init1: 6576 opt: 6576 Z-score: 4140.3 bits: 777.8 E(85289): 0
Smith-Waterman score: 6576; 100.0% identity (100.0% similar) in 970 aa overlap (205-1174:1-970)
180 190 200 210 220 230
pF1KE2 LQDEKVLEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISI
::::::::::::::::::::::::::::::
XP_011 MLYMQEVERMDGYGEESYPAKDSQGSDISI
10 20 30
240 250 260 270 280 290
pF1KE2 GACLEGIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GACLEGIFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIW
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE2 RLCVARHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLCVARHKFYRLNQCNLQTQTVTVNPIRRRSSSRMSLPKPQPYVMPPPPQLHYNGHYTEP
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE2 YASSQDNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YASSQDNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSP
160 170 180 190 200 210
420 430 440 450 460 470
pF1KE2 MSSNPSITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSNPSITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRN
220 230 240 250 260 270
480 490 500 510 520 530
pF1KE2 LNIGSSYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNIGSSYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAERRPVV
280 290 300 310 320 330
540 550 560 570 580 590
pF1KE2 GAVSVPELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAVSVPELTNAQLQAQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLSRHLYISSSNPDL
340 350 360 370 380 390
600 610 620 630 640 650
pF1KE2 ITRRVHHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITRRVHHSVQTFQEDSLPVAHSLQEVSEPLTAARHAQLHKRNSIEVAGLSHGLEGLRLKE
400 410 420 430 440 450
660 670 680 690 700 710
pF1KE2 RTLSASAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTLSASAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGLRYGHKKSLSDATMLIHSSEEE
460 470 480 490 500 510
720 730 740 750 760 770
pF1KE2 EDEDFEEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDEDFEEESGARAPPARAREPRPGLAQDPPGCPRVLLAGPLHILEPKAHVPDAEKRMMDS
520 530 540 550 560 570
780 790 800 810 820 830
pF1KE2 SPVRTTAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPVRTTAEAQRPWRDGLLMPSMSESDLTTSGRYRARRDSLKKRPVSDLLSGKKNIVEGLP
580 590 600 610 620 630
840 850 860 870 880 890
pF1KE2 PLGGMKKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLGGMKKTRVDAKKIGPLKLAALNGLSLSRVPLPDEGKEVATRATNDERCKILEQRLEQG
640 650 660 670 680 690
900 910 920 930 940 950
pF1KE2 MVFTEYERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVFTEYERILKKRLVDGECSTARLPENAERNRFQDVLPYDDVRVELVPTKENNTGYINAS
700 710 720 730 740 750
960 970 980 990 1000 1010
pF1KE2 HIKVSVSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HIKVSVSGIEWDYIATQGPLQNTCQDFWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRL
760 770 780 790 800 810
1020 1030 1040 1050 1060 1070
pF1KE2 GSRHNTVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSRHNTVTYGRFKITTRFRTDSGCYATTGLKMKHLLTGQERTVWHLQYTDWPEHGCPEDL
820 830 840 850 860 870
1080 1090 1100 1110 1120 1130
pF1KE2 KGFLSYLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGFLSYLEEIQSVRRHTNSTSDPQSPNPPLLVHCSAGVGRTGVVILSEIMIACLEHNEVL
880 890 900 910 920 930
1140 1150 1160 1170
pF1KE2 DIPRVLDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
::::::::::::::::::::::::::::::::::::::::
XP_011 DIPRVLDMLRQQRMMLVQTLCQYTFVYRVLIQFLKSSRLI
940 950 960 970
>>NP_005392 (OMIM: 603155,613611) tyrosine-protein phosp (1187 aa)
initn: 3257 init1: 1359 opt: 2539 Z-score: 1605.3 bits: 309.0 E(85289): 1.1e-82
Smith-Waterman score: 4164; 54.5% identity (78.5% similar) in 1210 aa overlap (3-1174:1-1187)
10 20 30 40 50 60
pF1KE2 MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
.::::::.:::::.: ::.:.:.::.::... .: :::::::::: ::::::::::::
NP_005 MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRE
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
. ::.::. .:..: :::.:::::::.:::.: :: ..:::.::::.:: :::: :::::
NP_005 THYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
:::.:::.::: . :::.:.:.::::::::::::..:..:::::....:::. .: :
NP_005 YLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
::: ::::: :. . :. .::..:..::::.::.:.: .:.::..:. . .: . :
NP_005 LEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
:::... ::. :..::.:..:..:::: . .:: ::::: :.:.:.:.:::: :: ..:
NP_005 IFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATR
240 250 260 270 280 290
310 320 330 340 350
pF1KE2 HKFYRLNQ-CNLQTQTVTVNPIRRRSS-SRMSLPKPQPYVMPPPPQLHYNGHYTEPYASS
::::. :. :. :... ::::. . :: :::. :::..:: ... . ::.: . .:
NP_005 HKFYKQNKICTEQSNSPP--PIRRQPTWSRSSLPRQQPYILPPV-HVQCGEHYSETH-TS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 QDNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSN
::..: :... ::.:..::: ::: . :::: :.::.:::: : ..: ::.:::
NP_005 QDSIFHGNEEALYCNSHNSLDLNY--LNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSN
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 PSITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIG
:: :::.:: ::.:::::::.: :::::::::::::.:..::..:.. ::.:::::::
NP_005 LSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNII
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 SSYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAER----RPVV
...::..: :::::::.::. : . . . : .. ::: : . .: .
NP_005 NTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVY--SNKLVSPSDQRNPKNNVVPSKPGA
480 490 500 510 520 530
540 550 560 570 580
pF1KE2 GA----VSVPELTNAQLQ-AQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLS--RHLYI
.: ::.:::.: ::: ...: . ..... ..::::::: ::::.:::::. :: :.
NP_005 SAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYV
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE2 SSSNPDLITRRVHHSVQTFQEDSLPVAH-SLQEVSEPLTAARH-AQLHKRNSIEVAG-LS
:.:.:::.::.:. ::.:::::: ::.: :::::::::::..: . ..::.:.:: . .
NP_005 SGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMV
600 610 620 630 640 650
650 660 670 680 690 700
pF1KE2 HGLEGLRLKERTLSASAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGL-RYGHKKSLSD
.:.:.. :: : .: : . . : . : .:. : .: :::..::
NP_005 RGMEAMTLKSLHLP-----MARRNTLREQGPP-----EEGSGSHEVPQLPQYHHKKTFSD
660 670 680 690 700
710 720 730 740 750
pF1KE2 ATMLIHSSEEEEDEDFEEESGARAPPARAR-----EPRPGLAQDP-------PGCPRVLL
::::::::: ::.:. :: . : : . . . .::. : :: . .
NP_005 ATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVS
710 720 730 740 750 760
760 770 780 790 800
pF1KE2 AGPLHILEPKAHVPDA--EKRMMDSSPVRTTAEAQR--PWRDGL-LMPSMSESDLTTSGR
: :. . .: .: : . :.. .:... . .. : .: : ::.:: ::: : .
NP_005 NGALR--QDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLT-SVK
770 780 790 800 810
810 820 830 840 850 860
pF1KE2 YRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMKKTRV---DAKKIGPLKLAALNGLSLS
:.... .:.::::...: . .:.: . ...: .. .:.: :: ::::::::..
NP_005 ERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQK-RPLMLAALNGLSVA
820 830 840 850 860 870
870 880 890 900 910 920
pF1KE2 RVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEYERILKKRLVDGECSTARLPENAE
:: .:.. :::. ::: . :...::.::::::::.: ::. ..: ::: ::::::
NP_005 RVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKK-ANGIFSTAALPENAE
880 890 900 910 920 930
930 940 950 960 970 980
pF1KE2 RNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSVSGIEWDYIATQGPLQNTCQDFWQ
:.:...:.::.. ::::.::::::::::::::::: :.: :: :::::::: .::.::::
NP_005 RSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQ
940 950 960 970 980 990
990 1000 1010 1020 1030 1040
pF1KE2 MVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNTVTYGRFKITTRFRTDSGCYATTG
::::::. .:::::::::::: :: ::::.:::.:...:::.::.::.::::: ::::::
NP_005 MVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTG
1000 1010 1020 1030 1040 1050
1050 1060 1070 1080 1090 1100
pF1KE2 LKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSYLEEIQSVRRHTNSTSD-PQSPNP
::.::::.:::::::::::::::.::::::..:::::::::::::::::: . .. .:
NP_005 LKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHP
1060 1070 1080 1090 1100 1110
1110 1120 1130 1140 1150 1160
pF1KE2 PLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVLDMLRQQRMMLVQTLCQYTFVYR
:..::::::::::::.::::.:: :::::: ...: .: .::.:::...::. :: :::.
NP_005 PIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQ
1120 1130 1140 1150 1160 1170
1170
pF1KE2 VLIQFLKSSRLI
::::::..::::
NP_005 VLIQFLQNSRLI
1180
>>XP_016857430 (OMIM: 603155,613611) PREDICTED: tyrosine (1187 aa)
initn: 3257 init1: 1359 opt: 2539 Z-score: 1605.3 bits: 309.0 E(85289): 1.1e-82
Smith-Waterman score: 4164; 54.5% identity (78.5% similar) in 1210 aa overlap (3-1174:1-1187)
10 20 30 40 50 60
pF1KE2 MPLPFGLKLKRTRRYTVSSKSCLVARIQLLNNEFVEFTLSVESTGQESLEAVAQRLELRE
.::::::.:::::.: ::.:.:.::.::... .: :::::::::: ::::::::::::
XP_016 MPFGLKLRRTRRYNVLSKNCFVTRIRLLDSNVIECTLSVESTGQECLEAVAQRLELRE
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 VTYFSLWYYNKQNQRRWVDLEKPLKKQLDKYALEPTVYFGVVFYVPSVSQLQQEITRYQY
. ::.::. .:..: :::.:::::::.:::.: :: ..:::.::::.:: :::: :::::
XP_016 THYFGLWFLSKSQQARWVELEKPLKKHLDKFANEPLLFFGVMFYVPNVSWLQQEATRYQY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 YLQLKKDILEGSIPCTLEQAIQLAGLAVQADFGDFDQYESQDFLQKFALFPVGWLQDEKV
:::.:::.::: . :::.:.:.::::::::::::..:..:::::....:::. .: :
XP_016 YLQVKKDVLEGRLRCTLDQVIRLAGLAVQADFGDYNQFDSQDFLREYVLFPMDLALEEAV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE2 LEEATQKVALLHQKYRGLTAPDAEMLYMQEVERMDGYGEESYPAKDSQGSDISIGACLEG
::: ::::: :. . :. .::..:..::::.::.:.: .:.::..:. . .: . :
XP_016 LEELTQKVAQEHKAHSGILPAEAELMYINEVERLDGFGQEIFPVKDNHGNCVHLGIFFMG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE2 IFVKHKNGRHPVVFRWHDIANMSHNKSFFALELANKEETIQFQTEDMETAKYIWRLCVAR
:::... ::. :..::.:..:..:::: . .:: ::::: :.:.:.:.:::: :: ..:
XP_016 IFVRNRIGRQAVIYRWNDMGNITHNKSTILVELINKEETALFHTDDIENAKYISRLFATR
240 250 260 270 280 290
310 320 330 340 350
pF1KE2 HKFYRLNQ-CNLQTQTVTVNPIRRRSS-SRMSLPKPQPYVMPPPPQLHYNGHYTEPYASS
::::. :. :. :... ::::. . :: :::. :::..:: ... . ::.: . .:
XP_016 HKFYKQNKICTEQSNSPP--PIRRQPTWSRSSLPRQQPYILPPV-HVQCGEHYSETH-TS
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE2 QDNLFVPNQNGYYCHSQTSLDRAQIDLNGRIRNGSVYSAHSTNSLNNPQPYLQPSPMSSN
::..: :... ::.:..::: ::: . :::: :.::.:::: : ..: ::.:::
XP_016 QDSIFHGNEEALYCNSHNSLDLNY--LNGTVTNGSVCSVHSVNSLNCSQSFIQASPVSSN
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE2 PSITGSDVMRPDYLPSHRHSAVIPPSYRPTPDYETVMKQLNRGLVHAERQSHSLRNLNIG
:: :::.:: ::.:::::::.: :::::::::::::.:..::..:.. ::.:::::::
XP_016 LSIPGSDIMRADYIPSHRHSAIIVPSYRPTPDYETVMRQMKRGILHTDSQSQSLRNLNII
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE2 SSYAYSRPAALVYSQPEIREHAQLPSPAAAHCPFSLSYSFHSPSPYPYPAER----RPVV
...::..: :::::::.::. : . . . : .. ::: : . .: .
XP_016 NTHAYNQPEDLVYSQPEMRERHPYTVPYGPQGVY--SNKLVSPSDQRNPKNNVVPSKPGA
480 490 500 510 520 530
540 550 560 570 580
pF1KE2 GA----VSVPELTNAQLQ-AQDYPSPNIMRTQVYRPPPPYPPPRPANSTPDLS--RHLYI
.: ::.:::.: ::: ...: . ..... ..::::::: ::::.:::::. :: :.
XP_016 SAISHTVSTPELANMQLQGSHNYSTAHMLKNYLFRPPPPYPRPRPATSTPDLASHRHKYV
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE2 SSSNPDLITRRVHHSVQTFQEDSLPVAH-SLQEVSEPLTAARH-AQLHKRNSIEVAG-LS
:.:.:::.::.:. ::.:::::: ::.: :::::::::::..: . ..::.:.:: . .
XP_016 SGSSPDLVTRKVQLSVKTFQEDSSPVVHQSLQEVSEPLTATKHHGTVNKRHSLEVMNSMV
600 610 620 630 640 650
650 660 670 680 690 700
pF1KE2 HGLEGLRLKERTLSASAAEVAPRAVSVGSQPSVFTERTQREGPEEAEGL-RYGHKKSLSD
.:.:.. :: : .: : . . : . : .:. : .: :::..::
XP_016 RGMEAMTLKSLHLP-----MARRNTLREQGPP-----EEGSGSHEVPQLPQYHHKKTFSD
660 670 680 690 700
710 720 730 740 750
pF1KE2 ATMLIHSSEEEEDEDFEEESGARAPPARAR-----EPRPGLAQDP-------PGCPRVLL
::::::::: ::.:. :: . : : . . . .::. : :: . .
XP_016 ATMLIHSSESEEEEEEAPESVPQIPMLREKMEYSAQLQAALARIPNKPPPEYPGPRKSVS
710 720 730 740 750 760
760 770 780 790 800
pF1KE2 AGPLHILEPKAHVPDA--EKRMMDSSPVRTTAEAQR--PWRDGL-LMPSMSESDLTTSGR
: :. . .: .: : . :.. .:... . .. : .: : ::.:: ::: : .
XP_016 NGALR--QDQASLPPAMARARVLRHGPAKAISMSRTDPPAVNGASLGPSISEPDLT-SVK
770 780 790 800 810
810 820 830 840 850 860
pF1KE2 YRARRDSLKKRPVSDLLSGKKNIVEGLPPLGGMKKTRV---DAKKIGPLKLAALNGLSLS
:.... .:.::::...: . .:.: . ...: .. .:.: :: ::::::::..
XP_016 ERVKKEPVKERPVSEMFSLEDSIIEREMMIRNLEKQKMAGLEAQK-RPLMLAALNGLSVA
820 830 840 850 860 870
870 880 890 900 910 920
pF1KE2 RVPLPDEGKEVATRATNDERCKILEQRLEQGMVFTEYERILKKRLVDGECSTARLPENAE
:: .:.. :::. ::: . :...::.::::::::.: ::. ..: ::: ::::::
XP_016 RVSGREENRVDATRVPMDERFRTLKKKLEEGMVFTEYEQIPKKK-ANGIFSTAALPENAE
880 890 900 910 920 930
930 940 950 960 970 980
pF1KE2 RNRFQDVLPYDDVRVELVPTKENNTGYINASHIKVSVSGIEWDYIATQGPLQNTCQDFWQ
:.:...:.::.. ::::.::::::::::::::::: :.: :: :::::::: .::.::::
XP_016 RSRIREVVPYEENRVELIPTKENNTGYINASHIKVVVGGAEWHYIATQGPLPHTCHDFWQ
940 950 960 970 980 990
990 1000 1010 1020 1030 1040
pF1KE2 MVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNTVTYGRFKITTRFRTDSGCYATTG
::::::. .:::::::::::: :: ::::.:::.:...:::.::.::.::::: ::::::
XP_016 MVWEQGVNVIAMVTAEEEGGRTKSHRYWPKLGSKHSSATYGKFKVTTKFRTDSVCYATTG
1000 1010 1020 1030 1040 1050
1050 1060 1070 1080 1090 1100
pF1KE2 LKMKHLLTGQERTVWHLQYTDWPEHGCPEDLKGFLSYLEEIQSVRRHTNSTSD-PQSPNP
::.::::.:::::::::::::::.::::::..:::::::::::::::::: . .. .:
XP_016 LKVKHLLSGQERTVWHLQYTDWPDHGCPEDVQGFLSYLEEIQSVRRHTNSMLEGTKNRHP
1060 1070 1080 1090 1100 1110
1110 1120 1130 1140 1150 1160
pF1KE2 PLLVHCSAGVGRTGVVILSEIMIACLEHNEVLDIPRVLDMLRQQRMMLVQTLCQYTFVYR
:..::::::::::::.::::.:: :::::: ...: .: .::.:::...::. :: :::.
XP_016 PIVVHCSAGVGRTGVLILSELMIYCLEHNEKVEVPMMLRLLREQRMFMIQTIAQYKFVYQ
1120 1130 1140 1150 1160 1170
1170
pF1KE2 VLIQFLKSSRLI
::::::..::::
XP_016 VLIQFLQNSRLI
1180
1174 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:52:01 2016 done: Tue Nov 8 10:52:03 2016
Total Scan time: 14.940 Total Display time: 0.430
Function used was FASTA [36.3.4 Apr, 2011]