FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2576, 169 aa 1>>>pF1KE2576 169 - 169 aa - 169 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0251+/-0.000851; mu= 13.9680+/- 0.051 mean_var=76.5092+/-15.445, 0's: 0 Z-trim(107.5): 63 B-trim: 5 in 1/50 Lambda= 0.146628 statistics sampled from 9579 (9642) to 9579 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.296), width: 16 Scan time: 1.870 The best scores are: opt bits E(32554) CCDS10677.1 MYLPF gene_id:29895|Hs108|chr16 ( 169) 1114 244.6 2.1e-65 CCDS31901.1 MYL2 gene_id:4633|Hs108|chr12 ( 166) 826 183.7 4.6e-47 CCDS34713.1 MYL10 gene_id:93408|Hs108|chr7 ( 226) 690 155.1 2.6e-38 CCDS5478.1 MYL7 gene_id:58498|Hs108|chr7 ( 175) 681 153.1 8.1e-38 CCDS43197.1 MYL5 gene_id:4636|Hs108|chr4 ( 173) 672 151.1 3e-37 CCDS11830.1 MYL12A gene_id:10627|Hs108|chr18 ( 171) 605 137.0 5.5e-33 CCDS77145.1 MYL12A gene_id:10627|Hs108|chr18 ( 177) 605 137.0 5.7e-33 CCDS11831.1 MYL12B gene_id:103910|Hs108|chr18 ( 172) 600 135.9 1.2e-32 CCDS13276.1 MYL9 gene_id:10398|Hs108|chr20 ( 172) 590 133.8 5e-32 CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 ( 149) 268 65.6 1.4e-11 CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 ( 149) 268 65.6 1.4e-11 CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 ( 149) 268 65.6 1.4e-11 CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 ( 149) 267 65.4 1.7e-11 >>CCDS10677.1 MYLPF gene_id:29895|Hs108|chr16 (169 aa) initn: 1114 init1: 1114 opt: 1114 Z-score: 1287.6 bits: 244.6 E(32554): 2.1e-65 Smith-Waterman score: 1114; 99.4% identity (100.0% similar) in 169 aa overlap (1-169:1-169) 10 20 30 40 50 60 pF1KE2 MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 NVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 NVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFL 70 80 90 100 110 120 130 140 150 160 pF1KE2 EELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE :::::::::::::::::::::::::::::::::::::::::::::.::: CCDS10 EELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAKDQE 130 140 150 160 >>CCDS31901.1 MYL2 gene_id:4633|Hs108|chr12 (166 aa) initn: 828 init1: 774 opt: 826 Z-score: 958.5 bits: 183.7 E(32554): 4.6e-47 Smith-Waterman score: 826; 71.3% identity (92.8% similar) in 167 aa overlap (1-167:1-166) 10 20 30 40 50 60 pF1KE2 MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRL ::::.::.:. :..:.:::::.::::::::::::..::::::.:::.::::::::.::. CCDS31 MAPKKAKKRA-GGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRV 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 NVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFL ::::::.: :.::: ::::::::::::::::::::::..: .::::.::::::..: .. CCDS31 NVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYV 60 70 80 90 100 110 130 140 150 160 pF1KE2 EELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE .:.:::: .:::.::. .:.::::::: ::.::::. ..::::. .: CCDS31 REMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD 120 130 140 150 160 >>CCDS34713.1 MYL10 gene_id:93408|Hs108|chr7 (226 aa) initn: 840 init1: 688 opt: 690 Z-score: 801.2 bits: 155.1 E(32554): 2.6e-38 Smith-Waterman score: 746; 59.8% identity (74.9% similar) in 199 aa overlap (3-167:28-226) 10 20 30 pF1KE2 MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKE--- :.::..:. .::.:::::::.::::::: CCDS34 MLLRLVSNSWPQVILPPRPPKVLGLQAPRRARKRAEGTASSNVFSMFDQSQIQEFKESLA 10 20 30 40 50 60 40 50 60 pF1KE2 -------------------------------AFTVIDQNRDGIIDKEDLRDTFAAMGRLN :::..::::::.::::::::::::.::.: CCDS34 LSPRLERNGMISAHCNLCLTGSSNSPASASQAFTIMDQNRDGFIDKEDLRDTFAALGRIN 70 80 90 100 110 120 70 80 90 100 110 120 pF1KE2 VKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKKFLE ::::::.::.::: ::::::::::::::::::.:::..: ::::.: :::: .: .. CCDS34 VKNEELEAMVKEAPGPINFTVFLTMFGEKLKGTDPEETILHAFKVFDTEGKGFVKADVIK 130 140 150 160 170 180 130 140 150 160 pF1KE2 ELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE : : :: ::::.::.:.:.::::::: ::.::.:.:::::::. .: CCDS34 EKLMTQADRFSEEEVKQMFAAFPPDVCGNLDYRNLCYVITHGEEKD 190 200 210 220 >>CCDS5478.1 MYL7 gene_id:58498|Hs108|chr7 (175 aa) initn: 707 init1: 674 opt: 681 Z-score: 792.4 bits: 153.1 E(32554): 8.1e-38 Smith-Waterman score: 681; 57.6% identity (86.7% similar) in 165 aa overlap (4-168:11-175) 10 20 30 40 50 pF1KE2 MAPKRAKRRTVEGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDT : : . .. :::.:::::.:.:::::::::. ::::::::: : :::.: CCDS54 MASRKAGTRGKVAATKQAQRGSSNVFSMFEQAQIQEFKEAFSCIDQNRDGIICKADLRET 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 FAAMGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKG .. .:...: .::::::..:..::::::::::.:::::.:.:::..: .::...:: ::: CCDS54 YSQLGKVSVPEEELDAMLQEGKGPINFTVFLTLFGEKLNGTDPEEAILSAFRMFDPSGKG 70 80 90 100 110 120 120 130 140 150 160 pF1KE2 TIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE ...: ...:: :: :.:: :...:.: : :..::.:::..::.::::: ... CCDS54 VVNKDEFKQLLLTQADKFSPAEVEQMFALTPMDLAGNIDYKSLCYIITHGDEKEE 130 140 150 160 170 >>CCDS43197.1 MYL5 gene_id:4636|Hs108|chr4 (173 aa) initn: 713 init1: 659 opt: 672 Z-score: 782.2 bits: 151.1 E(32554): 3e-37 Smith-Waterman score: 672; 57.1% identity (84.6% similar) in 175 aa overlap (1-168:1-173) 10 20 30 40 50 pF1KE2 MAPKRAKRRTVEGG-------SSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDT :: ...:.. ::: ::.::: :.::::::::::::..::::::.::::::.:: CCDS43 MASRKTKKK--EGGALRAQRASSNVFSNFEQTQIQEFKEAFTLMDQNRDGFIDKEDLKDT 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 FAAMGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKG .:..:. :::..:::::.::::::::::.::..:::::.:.: :..: .:::.:::.::: CCDS43 YASLGKTNVKDDELDAMLKEASGPINFTMFLNLFGEKLSGTDAEETILNAFKMLDPDGKG 60 70 80 90 100 110 120 130 140 150 160 pF1KE2 TIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE :.:.....:: .: :... ::. .:. ::.::.::: . ::::::. ... CCDS43 KINKEYIKRLLMSQADKMTAEEVDQMFQFASIDVAGNLDYKALSYVITHGEEKEE 120 130 140 150 160 170 >>CCDS11830.1 MYL12A gene_id:10627|Hs108|chr18 (171 aa) initn: 576 init1: 369 opt: 605 Z-score: 705.6 bits: 137.0 E(32554): 5.5e-33 Smith-Waterman score: 605; 55.2% identity (80.8% similar) in 172 aa overlap (1-169:1-170) 10 20 30 40 50 pF1KE2 MAPKRAKRRTV---EGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAM :. ::.: .: . ..:.::.::::.:::::::::..:::::::.::::::.: .:.. CCDS11 MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 GRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKK :. : .: :::::.:: ::::::.:::::::::.:.:::::: .:: .: :. :::.. CCDS11 GK-NPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE 70 80 90 100 110 120 130 140 150 160 pF1KE2 KFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE .:.:::::. :::..::. ... : : :: .: .. .. :: :.:.. CCDS11 DYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHG-AKDKDD 120 130 140 150 160 170 >>CCDS77145.1 MYL12A gene_id:10627|Hs108|chr18 (177 aa) initn: 576 init1: 369 opt: 605 Z-score: 705.5 bits: 137.0 E(32554): 5.7e-33 Smith-Waterman score: 605; 55.2% identity (80.8% similar) in 172 aa overlap (1-169:7-176) 10 20 30 40 50 pF1KE2 MAPKRAKRRTV---EGGSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLR :. ::.: .: . ..:.::.::::.:::::::::..:::::::.::::::. CCDS77 MDLTTTMSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLH 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 DTFAAMGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEG : .:..:. : .: :::::.:: ::::::.:::::::::.:.:::::: .:: .: :. CCDS77 DMLASLGK-NPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEA 70 80 90 100 110 120 130 140 150 160 pF1KE2 KGTIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE :::.. .:.:::::. :::..::. ... : : :: .: .. .. :: :.:.. CCDS77 TGTIQEDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHG-AKDKDD 120 130 140 150 160 170 >>CCDS11831.1 MYL12B gene_id:103910|Hs108|chr18 (172 aa) initn: 567 init1: 360 opt: 600 Z-score: 699.9 bits: 135.9 E(32554): 1.2e-32 Smith-Waterman score: 600; 54.3% identity (80.3% similar) in 173 aa overlap (1-169:1-171) 10 20 30 40 50 pF1KE2 MAPKRAKRRTVEG----GSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAA :. :.:: .:.. ..:.::.::::.:::::::::..:::::::.::::::.: .:. CCDS11 MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 MGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIK .:. : . :::::.:: ::::::.:::::::::.:.:::::: .:: .: :. :::. CCDS11 LGK-NPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQ 70 80 90 100 110 120 130 140 150 160 pF1KE2 KKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE . .:.:::::. :::..::. ... : : :: .: .. .. :: :.:.. CCDS11 EDYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHG-AKDKDD 120 130 140 150 160 170 >>CCDS13276.1 MYL9 gene_id:10398|Hs108|chr20 (172 aa) initn: 573 init1: 349 opt: 590 Z-score: 688.5 bits: 133.8 E(32554): 5e-32 Smith-Waterman score: 590; 54.3% identity (80.3% similar) in 173 aa overlap (1-169:1-171) 10 20 30 40 50 pF1KE2 MAPKRAKRRTVEG----GSSSVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAA :. :::: .:.. ..:.::.::::.:::::::::..:::::::.::::::.: .:. CCDS13 MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 MGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIK .:. : .: :..::.:: ::::::.:::::::::.:.:::::: .:: .: :..: :. CCDS13 LGK-NPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIH 70 80 90 100 110 120 130 140 150 160 pF1KE2 KKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE . :.:::::. :::..::. .:. : : :: .: .. .. :: :.:.. CCDS13 EDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHG-AKDKDD 120 130 140 150 160 170 >>CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 (149 aa) initn: 283 init1: 136 opt: 268 Z-score: 321.2 bits: 65.6 E(32554): 1.4e-11 Smith-Waterman score: 268; 34.5% identity (67.6% similar) in 148 aa overlap (21-161:1-147) 10 20 30 40 50 pF1KE2 MAPKRAKRRTVEGGSSSVFSMFDQT---QIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAM : :: :: ::::::...:.. :: : ..: .. .. CCDS18 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSL 10 20 30 40 60 70 80 90 100 110 pF1KE2 GRLNVKNEELDAMMKEA----SGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKG :. : . ::. :..:. .: :.: ::::...:.: .: :. : ::.:.: .:.: CCDS18 GQ-NPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNG 50 60 70 80 90 120 130 140 150 160 pF1KE2 TIKKKFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAEDQE :. :....:. .....::. .: : :.:.:... ..: CCDS18 YISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 100 110 120 130 140 169 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 18:10:52 2016 done: Fri Nov 4 18:10:53 2016 Total Scan time: 1.870 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]