FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2603, 979 aa 1>>>pF1KE2603 979 - 979 aa - 979 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.4633+/-0.000506; mu= -24.1866+/- 0.031 mean_var=417.3601+/-89.790, 0's: 0 Z-trim(119.2): 163 B-trim: 436 in 1/56 Lambda= 0.062780 statistics sampled from 32868 (33033) to 32868 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.387), width: 16 Scan time: 10.400 The best scores are: opt bits E(85289) XP_016861904 (OMIM: 157132) PREDICTED: microtubule (1068) 3736 353.6 3.1e-96 XP_016861903 (OMIM: 157132) PREDICTED: microtubule (1082) 3736 353.6 3.2e-96 XP_016861902 (OMIM: 157132) PREDICTED: microtubule (1083) 3736 353.6 3.2e-96 XP_016861898 (OMIM: 157132) PREDICTED: microtubule (1114) 3736 353.6 3.3e-96 NP_001127836 (OMIM: 157132) microtubule-associated (1135) 3736 353.6 3.3e-96 XP_016861894 (OMIM: 157132) PREDICTED: microtubule (1136) 3736 353.6 3.3e-96 XP_016861891 (OMIM: 157132) PREDICTED: microtubule (1151) 3736 353.6 3.4e-96 NP_002366 (OMIM: 157132) microtubule-associated pr (1152) 3736 353.6 3.4e-96 XP_016861895 (OMIM: 157132) PREDICTED: microtubule (1131) 3277 312.1 1.1e-83 XP_016861889 (OMIM: 157132) PREDICTED: microtubule (1168) 3277 312.1 1.1e-83 XP_016861888 (OMIM: 157132) PREDICTED: microtubule (1169) 3277 312.1 1.1e-83 XP_005265190 (OMIM: 157132) PREDICTED: microtubule (2314) 3184 303.7 7.1e-81 XP_005265191 (OMIM: 157132) PREDICTED: microtubule (2314) 3184 303.7 7.1e-81 XP_005265212 (OMIM: 157132) PREDICTED: microtubule (1129) 3130 298.7 1.1e-79 XP_016861897 (OMIM: 157132) PREDICTED: microtubule (1096) 3116 297.5 2.6e-79 XP_016861896 (OMIM: 157132) PREDICTED: microtubule (1097) 3116 297.5 2.6e-79 XP_016861893 (OMIM: 157132) PREDICTED: microtubule (1111) 3116 297.5 2.6e-79 XP_016861892 (OMIM: 157132) PREDICTED: microtubule (1112) 3116 297.5 2.6e-79 XP_016861887 (OMIM: 157132) PREDICTED: microtubule (1164) 3116 297.5 2.7e-79 XP_016861886 (OMIM: 157132) PREDICTED: microtubule (1165) 3116 297.5 2.7e-79 XP_016861885 (OMIM: 157132) PREDICTED: microtubule (1166) 3116 297.5 2.7e-79 XP_016861884 (OMIM: 157132) PREDICTED: microtubule (1180) 3116 297.5 2.8e-79 XP_011532021 (OMIM: 157132) PREDICTED: microtubule (1181) 3116 297.5 2.8e-79 XP_011532020 (OMIM: 157132) PREDICTED: microtubule (2239) 3023 289.1 1.7e-76 XP_016861881 (OMIM: 157132) PREDICTED: microtubule (2287) 3023 289.2 1.7e-76 XP_011532011 (OMIM: 157132) PREDICTED: microtubule (2288) 3023 289.2 1.7e-76 XP_011532010 (OMIM: 157132) PREDICTED: microtubule (2294) 3023 289.2 1.7e-76 XP_011532007 (OMIM: 157132) PREDICTED: microtubule (2309) 3023 289.2 1.7e-76 XP_006713215 (OMIM: 157132) PREDICTED: microtubule (2309) 3023 289.2 1.7e-76 XP_016861882 (OMIM: 157132) PREDICTED: microtubule (2309) 3023 289.2 1.7e-76 XP_016861880 (OMIM: 157132) PREDICTED: microtubule (2310) 3023 289.2 1.7e-76 XP_011532006 (OMIM: 157132) PREDICTED: microtubule (2311) 3023 289.2 1.7e-76 XP_011532005 (OMIM: 157132) PREDICTED: microtubule (2325) 3023 289.2 1.8e-76 XP_006713209 (OMIM: 157132) PREDICTED: microtubule (2326) 3023 289.2 1.8e-76 XP_006713210 (OMIM: 157132) PREDICTED: microtubule (2326) 3023 289.2 1.8e-76 XP_016861900 (OMIM: 157132) PREDICTED: microtubule (1111) 3005 287.4 2.8e-76 XP_016861890 (OMIM: 157132) PREDICTED: microtubule (1128) 3005 287.4 2.8e-76 XP_016861901 (OMIM: 157132) PREDICTED: microtubule (1110) 2996 286.6 4.9e-76 XP_005265214 (OMIM: 157132) PREDICTED: microtubule ( 975) 2735 263.0 5.7e-69 XP_016861906 (OMIM: 157132) PREDICTED: microtubule ( 974) 2726 262.1 1e-68 XP_016861883 (OMIM: 157132) PREDICTED: microtubule (2268) 2735 263.1 1.2e-68 XP_011532012 (OMIM: 157132) PREDICTED: microtubule (2285) 2735 263.1 1.2e-68 XP_016861905 (OMIM: 157132) PREDICTED: microtubule (1042) 2280 221.8 1.5e-56 XP_016861899 (OMIM: 157132) PREDICTED: microtubule (1113) 2280 221.8 1.6e-56 XP_016861909 (OMIM: 157132) PREDICTED: microtubule ( 936) 1667 166.2 7.2e-40 XP_016861908 (OMIM: 157132) PREDICTED: microtubule ( 937) 1667 166.2 7.2e-40 XP_016861910 (OMIM: 157132) PREDICTED: microtubule ( 905) 1552 155.8 9.5e-37 XP_005265215 (OMIM: 157132) PREDICTED: microtubule ( 906) 1552 155.8 9.5e-37 XP_016861907 (OMIM: 157132) PREDICTED: microtubule ( 959) 1362 138.6 1.5e-31 XP_016861911 (OMIM: 157132) PREDICTED: microtubule ( 890) 1359 138.3 1.7e-31 >>XP_016861904 (OMIM: 157132) PREDICTED: microtubule-ass (1068 aa) initn: 4433 init1: 3590 opt: 3736 Z-score: 1848.6 bits: 353.6 E(85289): 3.1e-96 Smith-Waterman score: 4823; 76.5% identity (76.5% similar) in 1095 aa overlap (1-922:1-1011) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 490 500 510 520 530 540 550 pF1KE2 EVALTEDQVPALKTEAP------------------------------------------- ::::::::::::::::: XP_016 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ XP_016 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ XP_016 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 670 680 690 700 710 720 560 570 580 590 600 pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 730 740 750 760 770 780 610 620 630 640 650 660 pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 790 800 810 820 830 840 670 680 690 700 710 720 pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 850 860 870 880 890 900 730 740 750 760 770 780 pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT ::::::::::::::::::::::::::::::::::::::: XP_016 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKV--------------------- 910 920 930 790 800 810 820 830 840 pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG XP_016 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ---QIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 940 950 960 970 980 990 910 920 930 940 950 960 pF1KE2 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA ::::::::::::::: XP_016 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA 1000 1010 1020 1030 1040 1050 >-- initn: 386 init1: 386 opt: 386 Z-score: 208.8 bits: 50.2 E(85289): 6.8e-05 Smith-Waterman score: 386; 100.0% identity (100.0% similar) in 57 aa overlap (923-979:1012-1068) 900 910 920 930 940 950 pF1KE2 KAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGL :::::::::::::::::::::::::::::: XP_016 KAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGL 990 1000 1010 1020 1030 1040 960 970 pF1KE2 NGHPTLSGGGDQREAQTLDSQIQETSI ::::::::::::::::::::::::::: XP_016 NGHPTLSGGGDQREAQTLDSQIQETSI 1050 1060 >>XP_016861903 (OMIM: 157132) PREDICTED: microtubule-ass (1082 aa) initn: 4506 init1: 3590 opt: 3736 Z-score: 1848.5 bits: 353.6 E(85289): 3.2e-96 Smith-Waterman score: 4860; 77.6% identity (77.6% similar) in 1080 aa overlap (1-907:1-1011) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 490 500 510 520 530 540 550 pF1KE2 EVALTEDQVPALKTEAP------------------------------------------- ::::::::::::::::: XP_016 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ XP_016 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ XP_016 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 670 680 690 700 710 720 560 570 580 590 600 pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 730 740 750 760 770 780 610 620 630 640 650 660 pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 790 800 810 820 830 840 670 680 690 700 710 720 pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 850 860 870 880 890 900 730 740 750 760 770 780 pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR------- 910 920 930 940 950 790 800 810 820 830 840 pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG XP_016 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 --VQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 960 970 980 990 1000 1010 910 920 930 940 950 960 pF1KE2 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA XP_016 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA 1020 1030 1040 1050 1060 1070 >-- initn: 548 init1: 475 opt: 475 Z-score: 252.3 bits: 58.3 E(85289): 2.6e-07 Smith-Waterman score: 475; 98.6% identity (100.0% similar) in 71 aa overlap (908-978:1012-1082) 880 890 900 910 920 930 pF1KE2 GGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAIS :::::::::::::::::::::::::::::: XP_016 GGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAIS 990 1000 1010 1020 1030 1040 940 950 960 970 pF1KE2 EAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI ::::::::::::::::::::::::::::::::::::::::. XP_016 EAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 1050 1060 1070 1080 >>XP_016861902 (OMIM: 157132) PREDICTED: microtubule-ass (1083 aa) initn: 4521 init1: 3590 opt: 3736 Z-score: 1848.5 bits: 353.6 E(85289): 3.2e-96 Smith-Waterman score: 4860; 77.6% identity (77.6% similar) in 1080 aa overlap (1-907:1-1011) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 490 500 510 520 530 540 550 pF1KE2 EVALTEDQVPALKTEAP------------------------------------------- ::::::::::::::::: XP_016 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ XP_016 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ XP_016 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 670 680 690 700 710 720 560 570 580 590 600 pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 730 740 750 760 770 780 610 620 630 640 650 660 pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 790 800 810 820 830 840 670 680 690 700 710 720 pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 850 860 870 880 890 900 730 740 750 760 770 780 pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR------- 910 920 930 940 950 790 800 810 820 830 840 pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG XP_016 ------------------------------------------------------------ 850 860 870 880 890 900 pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 --VQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 960 970 980 990 1000 1010 910 920 930 940 950 960 pF1KE2 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA XP_016 PAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREA 1020 1030 1040 1050 1060 1070 >-- initn: 484 init1: 484 opt: 484 Z-score: 256.7 bits: 59.1 E(85289): 1.5e-07 Smith-Waterman score: 484; 100.0% identity (100.0% similar) in 72 aa overlap (908-979:1012-1083) 880 890 900 910 920 930 pF1KE2 GGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAIS :::::::::::::::::::::::::::::: XP_016 GGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAIS 990 1000 1010 1020 1030 1040 940 950 960 970 pF1KE2 EAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI :::::::::::::::::::::::::::::::::::::::::: XP_016 EAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 1050 1060 1070 1080 >>XP_016861898 (OMIM: 157132) PREDICTED: microtubule-ass (1114 aa) initn: 4653 init1: 3590 opt: 3736 Z-score: 1848.3 bits: 353.6 E(85289): 3.3e-96 Smith-Waterman score: 4932; 79.9% identity (79.9% similar) in 1049 aa overlap (1-876:1-1011) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 490 500 510 520 530 540 550 pF1KE2 EVALTEDQVPALKTEAP------------------------------------------- ::::::::::::::::: XP_016 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ XP_016 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ XP_016 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 670 680 690 700 710 720 560 570 580 590 600 pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 730 740 750 760 770 780 610 620 630 640 650 660 pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 790 800 810 820 830 840 670 680 690 700 710 720 pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 850 860 870 880 890 900 730 740 750 760 770 780 pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR------- 910 920 930 940 950 790 800 810 820 830 840 pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG ::::::::::::::::::::::::::::: XP_016 -------------------------------VQIVSKKVSYSHIQSKCGSKDNIKHVPGG 960 970 980 850 860 870 880 890 900 pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL ::::::::::::::::::::::::::::: XP_016 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 990 1000 1010 1020 1030 1040 >-- initn: 683 init1: 683 opt: 683 Z-score: 353.9 bits: 77.1 E(85289): 5.7e-13 Smith-Waterman score: 683; 100.0% identity (100.0% similar) in 103 aa overlap (877-979:1012-1114) 850 860 870 880 890 900 pF1KE2 GGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGH :::::::::::::::::::::::::::::: XP_016 GGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGH 990 1000 1010 1020 1030 1040 910 920 930 940 950 960 pF1KE2 LPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQRE 1050 1060 1070 1080 1090 1100 970 pF1KE2 AQTLDSQIQETSI ::::::::::::: XP_016 AQTLDSQIQETSI 1110 >>NP_001127836 (OMIM: 157132) microtubule-associated pro (1135 aa) initn: 5863 init1: 3590 opt: 3736 Z-score: 1848.2 bits: 353.6 E(85289): 3.3e-96 Smith-Waterman score: 4991; 82.9% identity (82.9% similar) in 1011 aa overlap (1-838:1-1011) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 490 500 510 520 530 540 550 pF1KE2 EVALTEDQVPALKTEAP------------------------------------------- ::::::::::::::::: NP_001 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ NP_001 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ NP_001 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 670 680 690 700 710 720 560 570 580 590 600 pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 730 740 750 760 770 780 610 620 630 640 650 660 pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 790 800 810 820 830 840 670 680 690 700 710 720 pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 850 860 870 880 890 900 730 740 750 760 770 780 pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 910 920 930 940 950 960 790 800 810 820 830 840 pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 970 980 990 1000 1010 1020 850 860 870 880 890 900 pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL NP_001 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1030 1040 1050 1060 1070 1080 >-- initn: 670 init1: 507 opt: 507 Z-score: 267.6 bits: 61.2 E(85289): 3.6e-08 Smith-Waterman score: 507; 98.7% identity (98.7% similar) in 78 aa overlap (839-916:1012-1089) 810 820 830 840 850 860 pF1KE2 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS :::::::::::::::::::::::::::::: NP_001 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS 990 1000 1010 1020 1030 1040 870 880 890 900 910 920 pF1KE2 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP :::::::::::::::::::::::::::::::::::::::::::::: : NP_001 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIETYRLTFRANARA 1050 1060 1070 1080 1090 1100 930 940 950 960 970 pF1KE2 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI NP_001 RTDHGADIVSRPPHFPGGPNSGSRVLGPLSRAVH 1110 1120 1130 >>XP_016861894 (OMIM: 157132) PREDICTED: microtubule-ass (1136 aa) initn: 4862 init1: 3590 opt: 3736 Z-score: 1848.2 bits: 353.6 E(85289): 3.3e-96 Smith-Waterman score: 4952; 81.7% identity (81.7% similar) in 1026 aa overlap (1-853:1-1011) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 490 500 510 520 530 540 550 pF1KE2 EVALTEDQVPALKTEAP------------------------------------------- ::::::::::::::::: XP_016 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ XP_016 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ XP_016 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 670 680 690 700 710 720 560 570 580 590 600 pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 730 740 750 760 770 780 610 620 630 640 650 660 pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 790 800 810 820 830 840 670 680 690 700 710 720 pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 850 860 870 880 890 900 730 740 750 760 770 780 pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT :::::::::::::::::::::::::::::::::::::: ::::::: XP_016 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSK---------------AKVEKKT 910 920 930 940 790 800 810 820 830 840 pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 950 960 970 980 990 1000 850 860 870 880 890 900 pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL :::::: XP_016 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1010 1020 1030 1040 1050 1060 >-- initn: 1135 init1: 824 opt: 824 Z-score: 422.8 bits: 89.9 E(85289): 8.3e-17 Smith-Waterman score: 824; 99.2% identity (100.0% similar) in 125 aa overlap (854-978:1012-1136) 830 840 850 860 870 880 pF1KE2 KKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKI :::::::::::::::::::::::::::::: XP_016 KKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKI 990 1000 1010 1020 1030 1040 890 900 910 920 930 940 pF1KE2 ESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEA 1050 1060 1070 1080 1090 1100 950 960 970 pF1KE2 GAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI ::::::::::::::::::::::::::::::::::. XP_016 GAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 1110 1120 1130 >>XP_016861891 (OMIM: 157132) PREDICTED: microtubule-ass (1151 aa) initn: 6286 init1: 3590 opt: 3736 Z-score: 1848.1 bits: 353.6 E(85289): 3.4e-96 Smith-Waterman score: 4991; 82.9% identity (82.9% similar) in 1011 aa overlap (1-838:1-1011) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 490 500 510 520 530 540 550 pF1KE2 EVALTEDQVPALKTEAP------------------------------------------- ::::::::::::::::: XP_016 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ XP_016 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ XP_016 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 670 680 690 700 710 720 560 570 580 590 600 pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 730 740 750 760 770 780 610 620 630 640 650 660 pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 790 800 810 820 830 840 670 680 690 700 710 720 pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 850 860 870 880 890 900 730 740 750 760 770 780 pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 910 920 930 940 950 960 790 800 810 820 830 840 pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 970 980 990 1000 1010 1020 850 860 870 880 890 900 pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL XP_016 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1030 1040 1050 1060 1070 1080 >-- initn: 1349 init1: 930 opt: 930 Z-score: 474.6 bits: 99.5 E(85289): 1.1e-19 Smith-Waterman score: 930; 99.3% identity (100.0% similar) in 140 aa overlap (839-978:1012-1151) 810 820 830 840 850 860 pF1KE2 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS :::::::::::::::::::::::::::::: XP_016 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS 990 1000 1010 1020 1030 1040 870 880 890 900 910 920 pF1KE2 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP 1050 1060 1070 1080 1090 1100 930 940 950 960 970 pF1KE2 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI :::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 1110 1120 1130 1140 1150 >>NP_002366 (OMIM: 157132) microtubule-associated protei (1152 aa) initn: 3590 init1: 3590 opt: 3736 Z-score: 1848.1 bits: 353.6 E(85289): 3.4e-96 Smith-Waterman score: 4991; 82.9% identity (82.9% similar) in 1011 aa overlap (1-838:1-1011) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ESKKKPCSETSQIEDTPSSKPTLLANGGHGVEGSDTTGSPTEFLEEKMAYQEYPNSQNWP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTSIFAGQNDPLKDSYGMSP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELAKEIEMASEERPPAQALE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTKLDVTLAKDMQPSMESDM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVAPAKDVTLLKETERASPI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KE2 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENKIVPAKDLVLLSEIEVAQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KE2 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKDKALPLEAEVAPVKDMAQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KE2 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPPPETEVVLIKNVCLPPEM 490 500 510 520 530 540 550 pF1KE2 EVALTEDQVPALKTEAP------------------------------------------- ::::::::::::::::: NP_002 EVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETEATPVPIKDMEIAQTQKG 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ NP_002 ISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDSVLEKLGERKPCNSQPSE 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ NP_002 LSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQ 670 680 690 700 710 720 560 570 580 590 600 pF1KE2 ----------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK :::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAK 730 740 750 760 770 780 610 620 630 640 650 660 pF1KE2 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 APEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTE 790 800 810 820 830 840 670 680 690 700 710 720 pF1KE2 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPST 850 860 870 880 890 900 730 740 750 760 770 780 pF1KE2 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKT 910 920 930 940 950 960 790 800 810 820 830 840 pF1KE2 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGG 970 980 990 1000 1010 1020 850 860 870 880 890 900 pF1KE2 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL NP_002 GNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 1030 1040 1050 1060 1070 1080 >-- initn: 939 init1: 939 opt: 939 Z-score: 479.0 bits: 100.3 E(85289): 6.1e-20 Smith-Waterman score: 939; 100.0% identity (100.0% similar) in 141 aa overlap (839-979:1012-1152) 810 820 830 840 850 860 pF1KE2 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS :::::::::::::::::::::::::::::: NP_002 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS 990 1000 1010 1020 1030 1040 870 880 890 900 910 920 pF1KE2 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP 1050 1060 1070 1080 1090 1100 930 940 950 960 970 pF1KE2 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI 1110 1120 1130 1140 1150 >>XP_016861895 (OMIM: 157132) PREDICTED: microtubule-ass (1131 aa) initn: 4183 init1: 3120 opt: 3277 Z-score: 1623.5 bits: 312.1 E(85289): 1.1e-83 Smith-Waterman score: 4888; 78.6% identity (78.6% similar) in 1066 aa overlap (1-876:1-1028) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 pF1KE2 ESKKKPCSETSQIED-----------------TPSSKPTLLANGGHGVEGSDTTGSPTEF ::::::::::::::: :::::::::::::::::::::::::::: XP_016 ESKKKPCSETSQIEDLPLPPHPASLSFHLPLDTPSSKPTLLANGGHGVEGSDTTGSPTEF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE2 LEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE2 IFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE2 KEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE2 LDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVA 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE2 PAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KE2 IVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKD 430 440 450 460 470 480 470 480 490 500 510 520 pF1KE2 KALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP 490 500 510 520 530 540 530 540 550 pF1KE2 PETEVVLIKNVCLPPEMEVALTEDQVPALKTEAP-------------------------- :::::::::::::::::::::::::::::::::: XP_016 PETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETE 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ XP_016 ATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDS 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ XP_016 VLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKP 670 680 690 700 710 720 560 570 580 590 pF1KE2 ---------------------------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARP ::::::::::::::::::::::::::::::::: XP_016 LATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARP 730 740 750 760 770 780 600 610 620 630 640 650 pF1KE2 SILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSS 790 800 810 820 830 840 660 670 680 690 700 710 pF1KE2 RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG 850 860 870 880 890 900 720 730 740 750 760 770 pF1KE2 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 910 920 930 940 950 960 780 790 800 810 820 830 pF1KE2 NIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSH :::::::::: :::::::::::: XP_016 NIKHQPGGGR--------------------------------------VQIVSKKVSYSH 970 980 840 850 860 870 880 890 pF1KE2 IQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNF :::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNF 990 1000 1010 1020 1030 1040 900 910 920 930 940 950 pF1KE2 KEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSAS XP_016 KEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSAS 1050 1060 1070 1080 1090 1100 >-- initn: 683 init1: 683 opt: 683 Z-score: 353.8 bits: 77.1 E(85289): 5.7e-13 Smith-Waterman score: 683; 100.0% identity (100.0% similar) in 103 aa overlap (877-979:1029-1131) 850 860 870 880 890 900 pF1KE2 GGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGH :::::::::::::::::::::::::::::: XP_016 GGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGH 1000 1010 1020 1030 1040 1050 910 920 930 940 950 960 pF1KE2 LPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPAGGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQRE 1060 1070 1080 1090 1100 1110 970 pF1KE2 AQTLDSQIQETSI ::::::::::::: XP_016 AQTLDSQIQETSI 1120 1130 >>XP_016861889 (OMIM: 157132) PREDICTED: microtubule-ass (1168 aa) initn: 5816 init1: 3120 opt: 3277 Z-score: 1623.3 bits: 312.1 E(85289): 1.1e-83 Smith-Waterman score: 4947; 81.5% identity (81.5% similar) in 1028 aa overlap (1-838:1-1028) 10 20 30 40 50 60 pF1KE2 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MADLSLADALTEPSPDIEGEIKRDFIATLEAEAFDDVVGETVGKTDYIPLLDVDEKTGNS 10 20 30 40 50 60 70 80 90 100 pF1KE2 ESKKKPCSETSQIED-----------------TPSSKPTLLANGGHGVEGSDTTGSPTEF ::::::::::::::: :::::::::::::::::::::::::::: XP_016 ESKKKPCSETSQIEDLPLPPHPASLSFHLPLDTPSSKPTLLANGGHGVEGSDTTGSPTEF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KE2 LEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEEKMAYQEYPNSQNWPEDTNFCFQPEQVVDPIQTDPFKMYHDDDLADLVFPSSATADTS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KE2 IFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IFAGQNDPLKDSYGMSPCNTAVVPQGWSVEALNSPHSESFVSPEAVAEPPQPTAVPLELA 190 200 210 220 230 240 230 240 250 260 270 280 pF1KE2 KEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEIEMASEERPPAQALEIMMGLKTTDMAPSKETEMALAKDMALATKTEVALAKDMESPTK 250 260 270 280 290 300 290 300 310 320 330 340 pF1KE2 LDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDVTLAKDMQPSMESDMALVKDMELPTEKEVALVKDVRWPTETDVSSAKNVVLPTETEVA 310 320 330 340 350 360 350 360 370 380 390 400 pF1KE2 PAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAKDVTLLKETERASPIKMDLAPSKDMGPPKENKKETERASPIKMDLAPSKDMGPPKENK 370 380 390 400 410 420 410 420 430 440 450 460 pF1KE2 IVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IVPAKDLVLLSEIEVAQANDIISSTEISSAEKVALSSETEVALARDMTLPPETNVILTKD 430 440 450 460 470 480 470 480 490 500 510 520 pF1KE2 KALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALPLEAEVAPVKDMAQLPETEIAPAKDVAPSTVKEVGLLKDMSPLSETEMALGKDVTPP 490 500 510 520 530 540 530 540 550 pF1KE2 PETEVVLIKNVCLPPEMEVALTEDQVPALKTEAP-------------------------- :::::::::::::::::::::::::::::::::: XP_016 PETEVVLIKNVCLPPEMEVALTEDQVPALKTEAPLAKDGVLTLANNVTPAKDVPPLSETE 550 560 570 580 590 600 pF1KE2 ------------------------------------------------------------ XP_016 ATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTGKKCSLPAEEDS 610 620 630 640 650 660 pF1KE2 ------------------------------------------------------------ XP_016 VLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKP 670 680 690 700 710 720 560 570 580 590 pF1KE2 ---------------------------TTIGGLNKKPMSLASGLVPAAPPKRPAVASARP ::::::::::::::::::::::::::::::::: XP_016 LATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARP 730 740 750 760 770 780 600 610 620 630 640 650 pF1KE2 SILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSS 790 800 810 820 830 840 660 670 680 690 700 710 pF1KE2 RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSPSTLLPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAG 850 860 870 880 890 900 720 730 740 750 760 770 pF1KE2 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTE 910 920 930 940 950 960 780 790 800 810 820 830 pF1KE2 NIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSH 970 980 990 1000 1010 1020 840 850 860 870 880 890 pF1KE2 IQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNF :::::::: XP_016 IQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNF 1030 1040 1050 1060 1070 1080 >-- initn: 1349 init1: 930 opt: 930 Z-score: 474.5 bits: 99.5 E(85289): 1.1e-19 Smith-Waterman score: 930; 99.3% identity (100.0% similar) in 140 aa overlap (839-978:1029-1168) 810 820 830 840 850 860 pF1KE2 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS :::::::::::::::::::::::::::::: XP_016 ASAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGS 1000 1010 1020 1030 1040 1050 870 880 890 900 910 920 pF1KE2 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTEGGGSEAPLCPGP 1060 1070 1080 1090 1100 1110 930 940 950 960 970 pF1KE2 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETSI :::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 PAGEEPAISEAAPEAGAPTSASGLNGHPTLSGGGDQREAQTLDSQIQETN 1120 1130 1140 1150 1160 979 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 16:59:31 2016 done: Tue Nov 8 16:59:33 2016 Total Scan time: 10.400 Total Display time: 0.310 Function used was FASTA [36.3.4 Apr, 2011]