Result of FASTA (omim) for
pF1KE2610
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2610, 282 aa
1>>>pF1KE2610 282 - 282 aa - 282 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9360+/-0.000398; mu= 17.1220+/- 0.025
mean_var=61.4270+/-12.633, 0's: 0 Z-trim(111.5): 42 B-trim: 0 in 0/52
Lambda= 0.163642
statistics sampled from 20036 (20078) to 20036 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.593), E-opt: 0.2 (0.235), width: 16
Scan time: 5.910
The best scores are: opt bits E(85289)
NP_001643 (OMIM: 601383) aquaporin-6 [Homo sapiens ( 282) 1818 437.8 1.1e-122
NP_000477 (OMIM: 107777,125800) aquaporin-2 [Homo ( 271) 993 243.0 4.6e-64
NP_001642 (OMIM: 600442) aquaporin-5 [Homo sapiens ( 265) 954 233.8 2.7e-61
NP_036196 (OMIM: 154050,615274) lens fiber major i ( 263) 858 211.1 1.8e-54
XP_005268895 (OMIM: 600442) PREDICTED: aquaporin-5 ( 222) 791 195.3 8.9e-50
NP_004019 (OMIM: 600308) aquaporin-4 isoform M23 [ ( 301) 664 165.4 1.2e-40
XP_011524244 (OMIM: 600308) PREDICTED: aquaporin-4 ( 316) 664 165.4 1.3e-40
NP_001641 (OMIM: 600308) aquaporin-4 isoform M1 [H ( 323) 664 165.4 1.3e-40
NP_001304313 (OMIM: 600308) aquaporin-4 isoform M1 ( 352) 664 165.4 1.4e-40
NP_932766 (OMIM: 107776,110450) aquaporin-1 isofor ( 269) 634 158.2 1.5e-38
NP_001316801 (OMIM: 107776,110450) aquaporin-1 iso ( 323) 634 158.3 1.7e-38
XP_016874795 (OMIM: 154050,615274) PREDICTED: lens ( 144) 474 120.3 2.1e-27
XP_011536656 (OMIM: 154050,615274) PREDICTED: lens ( 168) 474 120.3 2.4e-27
NP_001304316 (OMIM: 600308) aquaporin-4 isoform de ( 296) 433 110.8 3.1e-24
NP_001160 (OMIM: 603750) aquaporin-8 [Homo sapiens ( 261) 373 96.6 5.2e-20
XP_011544124 (OMIM: 603750) PREDICTED: aquaporin-8 ( 262) 373 96.6 5.2e-20
XP_011544125 (OMIM: 603750) PREDICTED: aquaporin-8 ( 148) 197 54.9 1.1e-07
NP_001307564 (OMIM: 602914) aquaporin-9 isoform 2 ( 193) 198 55.2 1.1e-07
NP_066190 (OMIM: 602914) aquaporin-9 isoform 1 [Ho ( 295) 198 55.3 1.6e-07
NP_001305086 (OMIM: 602974,614411) aquaporin-7 iso ( 256) 176 50.1 5.1e-06
NP_001305087 (OMIM: 602974,614411) aquaporin-7 iso ( 257) 176 50.1 5.1e-06
XP_016870189 (OMIM: 602974,614411) PREDICTED: aqua ( 341) 176 50.2 6.4e-06
XP_011516168 (OMIM: 602974,614411) PREDICTED: aqua ( 342) 176 50.2 6.4e-06
NP_001161 (OMIM: 602974,614411) aquaporin-7 isofor ( 342) 176 50.2 6.4e-06
XP_005251510 (OMIM: 602974,614411) PREDICTED: aqua ( 342) 176 50.2 6.4e-06
NP_001305073 (OMIM: 600170,607457) aquaporin-3 iso ( 237) 168 48.2 1.8e-05
NP_004916 (OMIM: 600170,607457) aquaporin-3 isofor ( 292) 168 48.3 2.1e-05
NP_001307565 (OMIM: 602914) aquaporin-9 isoform 3 ( 230) 147 43.2 0.00054
NP_945349 (OMIM: 609789) aquaporin-12A precursor [ ( 295) 147 43.3 0.00066
>>NP_001643 (OMIM: 601383) aquaporin-6 [Homo sapiens] (282 aa)
initn: 1818 init1: 1818 opt: 1818 Z-score: 2323.5 bits: 437.8 E(85289): 1.1e-122
Smith-Waterman score: 1818; 100.0% identity (100.0% similar) in 282 aa overlap (1-282:1-282)
10 20 30 40 50 60
pF1KE2 MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIGISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIGISV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 ALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTK
190 200 210 220 230 240
250 260 270 280
pF1KE2 TLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
::::::::::::::::::::::::::::::::::::::::::
NP_001 TLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
250 260 270 280
>>NP_000477 (OMIM: 107777,125800) aquaporin-2 [Homo sapi (271 aa)
initn: 977 init1: 574 opt: 993 Z-score: 1271.1 bits: 243.0 E(85289): 4.6e-64
Smith-Waterman score: 993; 62.3% identity (85.4% similar) in 239 aa overlap (19-251:1-239)
10 20 30 40 50
pF1KE2 MDAVEPGGRGWASMLACRLWK----AISRALFAEFLATGLYVFFGVGSVMRWPTALPSVL
.:. :.:::.::::::: :.::::.::.. :: ::::::
NP_000 MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVL
10 20 30 40
60 70 80 90 100 110
pF1KE2 QIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAA
:::..:.: . ::. . :::: :::::.: ::: :.:. ::. ::::::.::..:::
NP_000 QIAMAFGLGIGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAA
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 LLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSR--QTSGSPAT
::. . :.::: :..:.. ::...::::.:::.::::::::.::::: : .. :.::
NP_000 LLHEITPADIRGDLAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPAL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 MIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFV
::.:::::::.:::.::::::::::..::.. ::: :::::.:::.::.:.::.::.:
NP_000 SIGFSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYV
170 180 190 200 210 220
240 250 260 270 280
pF1KE2 LFPDTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
::: .:.:..:::.: :
NP_000 LFPPAKSLSERLAVLKGLEPDTDWEEREVRRRQSVELHSPQSLPRGTKA
230 240 250 260 270
>>NP_001642 (OMIM: 600442) aquaporin-5 [Homo sapiens] (265 aa)
initn: 955 init1: 564 opt: 954 Z-score: 1221.5 bits: 233.8 E(85289): 2.7e-61
Smith-Waterman score: 954; 58.5% identity (88.1% similar) in 236 aa overlap (22-254:9-244)
10 20 30 40 50 60
pF1KE2 MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAI
:. .:.::::::: ..::::.::...::.:::..::::.
NP_001 MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIAL
10 20 30 40
70 80 90 100 110 120
pF1KE2 TFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYG
.:.:. . .:. .::.: :::.:::.:::..::: :: ::::::::: .::..:::
NP_001 AFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYG
50 60 70 80 90 100
130 140 150 160 170
pF1KE2 VMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGI
: : . : .:..:.. :... :::..:::.::.::.::.:::::::.:: :::: ::.
NP_001 VAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 SVALGHLIGIHFTGCSMNPARSFGPAIIIGKFT-VHWVFWVGPLMGALLASLIYNFVLFP
::.::::.::.:::::::::::::::.....:. .::::::::..::.::...: ..:::
NP_001 SVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFP
170 180 190 200 210 220
240 250 260 270 280
pF1KE2 DTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
.. .:..:.::. :: :
NP_001 NSLSLSERVAIIKGTYEPDEDWEEQREERKKTMELTTR
230 240 250 260
>>NP_036196 (OMIM: 154050,615274) lens fiber major intri (263 aa)
initn: 851 init1: 507 opt: 858 Z-score: 1099.1 bits: 211.1 E(85289): 1.8e-54
Smith-Waterman score: 858; 52.6% identity (83.3% similar) in 251 aa overlap (25-271:11-261)
10 20 30 40 50 60
pF1KE2 MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAI
::.::::.:: .:::::.:: .:: . :::.:.
NP_036 MWELRSASFWRAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVAM
10 20 30 40
70 80 90 100 110 120
pF1KE2 TFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYG
.:.:. : :: . . ::::.:::::.::::::..:: :: :.::::.::..:::.::.
NP_036 AFGLALATLVQSVGHISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYS
50 60 70 80 90 100
130 140 150 160 170
pF1KE2 VMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGI
: : .: .:..:... .::.:::..::..::::.:::.::. : :... :: : .:.
NP_036 VTPPAVRGNLALNTLHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 SVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPD
:.:::::.:...:: .:::::::.:::. :.:: :::.::::..:. :.::.:.:.:::
NP_036 SLALGHLFGMYYTGAGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPR
170 180 190 200 210 220
240 250 260 270 280
pF1KE2 TKTLAQRLAILTGTV-EVGTGAG-AGAEPLKKESQPGSGAVEMESV
:....::..: :. .:..: . .::.. ..:
NP_036 LKSISERLSVLKGAKPDVSNGQPEVTGEPVELNTQAL
230 240 250 260
>>XP_005268895 (OMIM: 600442) PREDICTED: aquaporin-5 iso (222 aa)
initn: 778 init1: 561 opt: 791 Z-score: 1014.7 bits: 195.3 E(85289): 8.9e-50
Smith-Waterman score: 791; 59.7% identity (87.8% similar) in 196 aa overlap (22-214:9-204)
10 20 30 40 50 60
pF1KE2 MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAI
:. .:.::::::: ..::::.::...::.:::..::::.
XP_005 MKKEVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIAL
10 20 30 40
70 80 90 100 110 120
pF1KE2 TFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYG
.:.:. . .:. .::.: :::.:::.:::..::: :: ::::::::: .::..:::
XP_005 AFGLAIGTLAQALGPVSGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYG
50 60 70 80 90 100
130 140 150 160 170
pF1KE2 VMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGI
: : . : .:..:.. :... :::..:::.::.::.::.:::::::.:: :::: ::.
XP_005 VAPLNARGNLAVNALNNNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGL
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 SVALGHLIGIHFTGCSMNPARSFGPAIIIGKFT-VHWVFWVGPLMGALLASLIYNFVLFP
::.::::.::.:::::::::::::::.....:. .::
XP_005 SVTLGHLVGIYFTGCSMNPARSFGPAVVMNRFSPAHWGLLLSLRGGDTRSVHPSL
170 180 190 200 210 220
240 250 260 270 280
pF1KE2 DTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
>>NP_004019 (OMIM: 600308) aquaporin-4 isoform M23 [Homo (301 aa)
initn: 602 init1: 313 opt: 664 Z-score: 850.7 bits: 165.4 E(85289): 1.2e-40
Smith-Waterman score: 664; 44.3% identity (77.9% similar) in 235 aa overlap (14-240:1-235)
10 20 30 40 50
pF1KE2 MDAVEPGGRGWASMLACR-LW-KAISRALFAEFLATGLYVFFGVGSVMRW---PTALP-S
:.: . .: .:. .:. ::::: ..:....::.. : :: .
NP_004 MVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVD
10 20 30 40
60 70 80 90 100 110
pF1KE2 VLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVG
.. :.. :.: : :: . ::.: :::::.:.. .::. ..: :.::: .:: .:
NP_004 MVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 AALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQT--SGSP
:..:: : : .. ::...:......:... :::..:.:::. .::: ::..: .::
NP_004 AGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 ATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYN
: ::.:::.:::..:..:: :::::::::::.:.:.. ::..::::..::.::. .:.
NP_004 ALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYE
170 180 190 200 210 220
240 250 260 270 280
pF1KE2 FVLFPDTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
.:. ::..
NP_004 YVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRGEE
230 240 250 260 270 280
>>XP_011524244 (OMIM: 600308) PREDICTED: aquaporin-4 iso (316 aa)
initn: 602 init1: 313 opt: 664 Z-score: 850.4 bits: 165.4 E(85289): 1.3e-40
Smith-Waterman score: 664; 44.3% identity (77.9% similar) in 235 aa overlap (14-240:16-250)
10 20 30 40 50
pF1KE2 MDAVEPGGRGWASMLACR-LW-KAISRALFAEFLATGLYVFFGVGSVMRW---PTALP
:.: . .: .:. .:. ::::: ..:....::.. : ::
XP_011 MFEIKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 -SVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGAT
... :.. :.: : :: . ::.: :::::.:.. .::. ..: :.::: .::
XP_011 VDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 VGAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQT--SG
.::..:: : : .. ::...:......:... :::..:.:::. .::: ::..: .:
XP_011 IGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 SPATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLI
: : ::.:::.:::..:..:: :::::::::::.:.:.. ::..::::..::.::. .
XP_011 SIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGL
190 200 210 220 230 240
240 250 260 270 280
pF1KE2 YNFVLFPDTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
:..:. ::..
XP_011 YEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDVDRG
250 260 270 280 290 300
>>NP_001641 (OMIM: 600308) aquaporin-4 isoform M1 [Homo (323 aa)
initn: 602 init1: 313 opt: 664 Z-score: 850.2 bits: 165.4 E(85289): 1.3e-40
Smith-Waterman score: 664; 44.3% identity (77.9% similar) in 235 aa overlap (14-240:23-257)
10 20 30 40
pF1KE2 MDAVEPGGRGWASMLACR-LW-KAISRALFAEFLATGLYVFFGVGSVMRW-
:.: . .: .:. .:. ::::: ..:....::.. :
NP_001 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 --PTALP-SVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVA
:: ... :.. :.: : :: . ::.: :::::.:.. .::. ..: :.:
NP_001 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 AQLVGATVGAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDS
:: .:: .::..:: : : .. ::...:......:... :::..:.:::. .::: ::
NP_001 AQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 RQT--SGSPATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMG
..: .:: : ::.:::.:::..:..:: :::::::::::.:.:.. ::..::::..:
NP_001 KRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 ALLASLIYNFVLFPDTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
:.::. .:..:. ::..
NP_001 AVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVH
250 260 270 280 290 300
>>NP_001304313 (OMIM: 600308) aquaporin-4 isoform M1x [H (352 aa)
initn: 602 init1: 313 opt: 664 Z-score: 849.7 bits: 165.4 E(85289): 1.4e-40
Smith-Waterman score: 664; 44.3% identity (77.9% similar) in 235 aa overlap (14-240:23-257)
10 20 30 40
pF1KE2 MDAVEPGGRGWASMLACR-LW-KAISRALFAEFLATGLYVFFGVGSVMRW-
:.: . .: .:. .:. ::::: ..:....::.. :
NP_001 MSDRPTARRWGKCGPLCTRENIMVAFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 --PTALP-SVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVA
:: ... :.. :.: : :: . ::.: :::::.:.. .::. ..: :.:
NP_001 GTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 AQLVGATVGAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDS
:: .:: .::..:: : : .. ::...:......:... :::..:.:::. .::: ::
NP_001 AQCLGAIIGAGILYLVTPPSVVGGLGVTMVHGNLTAGHGLLVELIITFQLVFTIFASCDS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE2 RQT--SGSPATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMG
..: .:: : ::.:::.:::..:..:: :::::::::::.:.:.. ::..::::..:
NP_001 KRTDVTGSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIG
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE2 ALLASLIYNFVLFPDTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
:.::. .:..:. ::..
NP_001 AVLAGGLYEYVFCPDVEFKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVH
250 260 270 280 290 300
>>NP_932766 (OMIM: 107776,110450) aquaporin-1 isoform 1 (269 aa)
initn: 697 init1: 326 opt: 634 Z-score: 813.1 bits: 158.2 E(85289): 1.5e-38
Smith-Waterman score: 686; 46.2% identity (76.2% similar) in 240 aa overlap (25-254:12-251)
10 20 30 40 50
pF1KE2 MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVM--RWP-----TALP
::. :::::: :.::...::.. ..: ::.
NP_932 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQ
10 20 30 40
60 70 80 90 100 110
pF1KE2 SVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATV
. ......:.: : .: . . :::: ::::::..:.. .::. ::. :. :: ::: :
NP_932 DNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 GAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTS--GS
..:.: :. . ..:: : . ..:..::....:.. ::::::::.:.:: :. . ::
NP_932 ATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE2 PATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIY
::.:::::::..: .:::..::::::: :.: .:. ::.:::::..:. :: :::
NP_932 APLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIY
170 180 190 200 210 220
240 250 260 270 280
pF1KE2 NFVLFPDTKTLAQRLAILT-GTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
.:.: : .. :..:. . : : ::
NP_932 DFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK
230 240 250 260
282 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:03:34 2016 done: Tue Nov 8 17:03:35 2016
Total Scan time: 5.910 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]