Result of FASTA (ccds) for
pF1KE2617
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2617, 2186 aa
1>>>pF1KE2617 2186 - 2186 aa - 2186 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1335+/-0.00116; mu= 12.4223+/- 0.069
mean_var=144.2901+/-30.468, 0's: 0 Z-trim(107.8): 106 B-trim: 446 in 1/50
Lambda= 0.106772
statistics sampled from 9684 (9788) to 9684 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.301), width: 16
Scan time: 6.720
The best scores are: opt bits E(32554)
CCDS44788.1 CACNA1C gene_id:775|Hs108|chr12 (2186) 14485 2244.5 0
CCDS44792.1 CACNA1C gene_id:775|Hs108|chr12 (2179) 9787 1520.8 0
CCDS44789.1 CACNA1C gene_id:775|Hs108|chr12 (2158) 8679 1350.1 0
CCDS44790.1 CACNA1C gene_id:775|Hs108|chr12 (2166) 8191 1274.9 0
CCDS44791.1 CACNA1C gene_id:775|Hs108|chr12 (2138) 6304 984.3 0
CCDS44794.1 CACNA1C gene_id:775|Hs108|chr12 (2138) 6304 984.3 0
CCDS44796.1 CACNA1C gene_id:775|Hs108|chr12 (2144) 6304 984.3 0
CCDS44795.1 CACNA1C gene_id:775|Hs108|chr12 (2146) 6304 984.3 0
CCDS44793.1 CACNA1C gene_id:775|Hs108|chr12 (2157) 6304 984.3 0
CCDS53735.1 CACNA1C gene_id:775|Hs108|chr12 (2157) 6304 984.3 0
CCDS44797.1 CACNA1C gene_id:775|Hs108|chr12 (2155) 6277 980.1 0
CCDS44800.1 CACNA1C gene_id:775|Hs108|chr12 (2138) 6253 976.4 0
CCDS44798.1 CACNA1C gene_id:775|Hs108|chr12 (2138) 6253 976.4 0
CCDS44801.1 CACNA1C gene_id:775|Hs108|chr12 (2146) 6253 976.4 0
CCDS44799.1 CACNA1C gene_id:775|Hs108|chr12 (2157) 6253 976.4 0
CCDS53736.1 CACNA1C gene_id:775|Hs108|chr12 (2173) 6253 976.4 0
CCDS53734.1 CACNA1C gene_id:775|Hs108|chr12 (2138) 6248 975.6 0
CCDS53733.1 CACNA1C gene_id:775|Hs108|chr12 (2173) 6248 975.6 0
CCDS44787.1 CACNA1C gene_id:775|Hs108|chr12 (2138) 6197 967.8 0
CCDS46849.1 CACNA1D gene_id:776|Hs108|chr3 (2137) 2070 332.1 1.7e-89
CCDS46848.1 CACNA1D gene_id:776|Hs108|chr3 (2161) 2069 331.9 1.9e-89
CCDS2872.1 CACNA1D gene_id:776|Hs108|chr3 (2181) 2069 331.9 1.9e-89
CCDS59166.1 CACNA1F gene_id:778|Hs108|chrX (1912) 2002 321.6 2.1e-86
CCDS59167.1 CACNA1F gene_id:778|Hs108|chrX (1966) 2002 321.6 2.2e-86
CCDS35253.1 CACNA1F gene_id:778|Hs108|chrX (1977) 2002 321.6 2.2e-86
CCDS45998.1 CACNA1A gene_id:773|Hs108|chr19 (2506) 1968 316.4 1e-84
CCDS82301.1 CACNA1A gene_id:773|Hs108|chr19 (2266) 1967 316.2 1e-84
CCDS82300.1 CACNA1A gene_id:773|Hs108|chr19 (2512) 1967 316.2 1.1e-84
CCDS45999.1 CACNA1A gene_id:773|Hs108|chr19 (2261) 1966 316.1 1.2e-84
CCDS82302.1 CACNA1A gene_id:773|Hs108|chr19 (2263) 1966 316.1 1.2e-84
CCDS1407.1 CACNA1S gene_id:779|Hs108|chr1 (1873) 1922 309.2 1.1e-82
CCDS59523.1 CACNA1B gene_id:774|Hs108|chr9 (2237) 1233 203.1 1.1e-50
CCDS59522.1 CACNA1B gene_id:774|Hs108|chr9 (2339) 1233 203.1 1.2e-50
CCDS55665.1 CACNA1E gene_id:777|Hs108|chr1 (2251) 1176 194.4 5e-48
CCDS53443.1 CACNA1E gene_id:777|Hs108|chr1 (2270) 1176 194.4 5e-48
CCDS55664.1 CACNA1E gene_id:777|Hs108|chr1 (2313) 1173 193.9 7e-48
CCDS44891.1 SCN8A gene_id:6334|Hs108|chr12 (1980) 756 129.6 1.3e-28
CCDS81692.1 SCN8A gene_id:6334|Hs108|chr12 (1980) 756 129.6 1.3e-28
CCDS46799.1 SCN5A gene_id:6331|Hs108|chr3 (2016) 732 125.9 1.7e-27
CCDS46796.1 SCN5A gene_id:6331|Hs108|chr3 (2016) 732 125.9 1.7e-27
CCDS54569.1 SCN5A gene_id:6331|Hs108|chr3 (1962) 729 125.5 2.4e-27
CCDS46797.1 SCN5A gene_id:6331|Hs108|chr3 (2015) 729 125.5 2.4e-27
CCDS33736.1 SCN10A gene_id:6336|Hs108|chr3 (1956) 697 120.6 7.1e-26
CCDS53794.1 SCN8A gene_id:6334|Hs108|chr12 (1939) 620 108.7 2.6e-22
CCDS33737.1 SCN11A gene_id:11280|Hs108|chr3 (1791) 570 101.0 5.1e-20
CCDS45736.1 CACNA1G gene_id:8913|Hs108|chr17 (2171) 503 90.7 7.8e-17
CCDS58571.1 CACNA1G gene_id:8913|Hs108|chr17 (2194) 503 90.7 7.8e-17
CCDS45735.1 CACNA1G gene_id:8913|Hs108|chr17 (2250) 503 90.7 8e-17
CCDS54143.1 CACNA1G gene_id:8913|Hs108|chr17 (2273) 503 90.7 8.1e-17
CCDS54146.1 CACNA1G gene_id:8913|Hs108|chr17 (2298) 503 90.7 8.1e-17
>>CCDS44788.1 CACNA1C gene_id:775|Hs108|chr12 (2186 aa)
initn: 14485 init1: 14485 opt: 14485 Z-score: 12055.7 bits: 2244.5 E(32554): 0
Smith-Waterman score: 14485; 100.0% identity (100.0% similar) in 2186 aa overlap (1-2186:1-2186)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2110 2120 2130 2140 2150 2160
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
CCDS44 DAGCVRARGRPSEEELQDSRVYVSSL
2170 2180
>>CCDS44792.1 CACNA1C gene_id:775|Hs108|chr12 (2179 aa)
initn: 10271 init1: 6296 opt: 9787 Z-score: 8144.6 bits: 1520.8 E(32554): 0
Smith-Waterman score: 13961; 96.0% identity (96.0% similar) in 2227 aa overlap (1-2186:1-2179)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1250 1260 1270
1330 1340 1350 1360
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM-----------------
:::::::::::::::::::::::::::::::::::::::
CCDS44 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPV
1280 1290 1300 1310 1320 1330
1370 1380 1390 1400 1410
pF1KE2 -----NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML
1340 1350 1360 1370 1380 1390
1420 1430 1440 1450 1460 1470
pF1KE2 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK
1400 1410 1420 1430 1440 1450
1480 1490 1500 1510 1520 1530
pF1KE2 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG
1460 1470 1480 1490 1500 1510
1540 1550 1560 1570 1580 1590
pF1KE2 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL
1520 1530 1540 1550 1560 1570
1600 1610 1620 1630
pF1KE2 NSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQANEELRAIIKK
::::::::::::::::::::::::: ::::::::::::::::
CCDS44 NSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKK
1580 1590 1600 1610 1620 1630
1640 1650 1660 1670 1680 1690
pF1KE2 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL
1640 1650 1660 1670 1680 1690
1700 1710 1720 1730 1740 1750
pF1KE2 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ
1700 1710 1720 1730 1740 1750
1760 1770 1780 1790 1800 1810
pF1KE2 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN
1760 1770 1780 1790 1800 1810
1820 1830 1840 1850 1860 1870
pF1KE2 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEET
1820 1830 1840 1850 1860 1870
1880 1890 1900 1910 1920 1930
pF1KE2 SQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSA
1880 1890 1900 1910 1920 1930
1940 1950 1960 1970 1980 1990
pF1KE2 SLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRP
1940 1950 1960 1970 1980 1990
2000 2010 2020 2030 2040 2050
pF1KE2 FATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRV
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
CCDS44 FATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRV
2000 2010 2020 2030 2040 2050
2060 2070 2080 2090 2100 2110
pF1KE2 RPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTI
2060 2070 2080 2090 2100 2110
2120 2130 2140 2150 2160 2170
pF1KE2 EEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDS
2120 2130 2140 2150 2160 2170
2180
pF1KE2 RVYVSSL
:::::::
CCDS44 RVYVSSL
>>CCDS44789.1 CACNA1C gene_id:775|Hs108|chr12 (2158 aa)
initn: 8678 init1: 8678 opt: 8679 Z-score: 7222.3 bits: 1350.1 E(32554): 0
Smith-Waterman score: 14232; 98.7% identity (98.7% similar) in 2186 aa overlap (1-2186:1-2158)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1780 1790 1800 1810 1820 1830
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1840 1850 1860 1870 1880 1890
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2020 2030 2040 2050 2060 2070
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2080 2090 2100 2110 2120 2130
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
CCDS44 DAGCVRARGRPSEEELQDSRVYVSSL
2140 2150
>>CCDS44790.1 CACNA1C gene_id:775|Hs108|chr12 (2166 aa)
initn: 8144 init1: 8144 opt: 8191 Z-score: 6816.0 bits: 1274.9 E(32554): 0
Smith-Waterman score: 14316; 99.0% identity (99.1% similar) in 2186 aa overlap (1-2186:1-2166)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2090 2100 2110 2120 2130 2140
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
CCDS44 DAGCVRARGRPSEEELQDSRVYVSSL
2150 2160
>>CCDS44791.1 CACNA1C gene_id:775|Hs108|chr12 (2138 aa)
initn: 11963 init1: 6296 opt: 6304 Z-score: 5245.2 bits: 984.3 E(32554): 0
Smith-Waterman score: 14061; 97.8% identity (97.8% similar) in 2186 aa overlap (1-2186:1-2138)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
:::: ::::::::::::::::::::::::::::
CCDS44 SETN----------------------------PAEHTQCSPSMNAEENSRISITFFRLFR
1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1580 1590 1600 1610 1620 1630
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1640 1650 1660 1670 1680 1690
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1700 1710 1720 1730 1740 1750
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1760 1770 1780 1790 1800 1810
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1820 1830 1840 1850 1860 1870
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1880 1890 1900 1910 1920 1930
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1940 1950 1960 1970 1980 1990
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2000 2010 2020 2030 2040 2050
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2060 2070 2080 2090 2100 2110
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
CCDS44 DAGCVRARGRPSEEELQDSRVYVSSL
2120 2130
>>CCDS44794.1 CACNA1C gene_id:775|Hs108|chr12 (2138 aa)
initn: 12026 init1: 6296 opt: 6304 Z-score: 5245.2 bits: 984.3 E(32554): 0
Smith-Waterman score: 14063; 97.8% identity (97.8% similar) in 2186 aa overlap (1-2186:1-2138)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1580 1590 1600 1610 1620 1630
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1640 1650 1660 1670 1680 1690
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1700 1710 1720 1730 1740 1750
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1760 1770 1780 1790 1800 1810
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1820 1830 1840 1850 1860 1870
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1880 1890 1900 1910 1920 1930
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1940 1950 1960 1970 1980 1990
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2000 2010 2020 2030 2040 2050
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2060 2070 2080 2090 2100 2110
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
CCDS44 DAGCVRARGRPSEEELQDSRVYVSSL
2120 2130
>>CCDS44796.1 CACNA1C gene_id:775|Hs108|chr12 (2144 aa)
initn: 10176 init1: 6296 opt: 6304 Z-score: 5245.1 bits: 984.3 E(32554): 0
Smith-Waterman score: 13884; 96.3% identity (96.4% similar) in 2205 aa overlap (1-2186:1-2144)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
:::::::::::::::::::::::::: :::::::::::::::::
CCDS44 ----HYFCDAWNTFDALIVVGSIVDIAITE-------------NAEENSRISITFFRLFR
1280 1290 1300 1310
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1320 1330 1340 1350 1360 1370
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1380 1390 1400 1410 1420 1430
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1440 1450 1460 1470 1480 1490
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1500 1510 1520 1530 1540 1550
1630 1640 1650 1660
pF1KE2 KTE-------------------GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV
::: ::::::::::::::::::::::::::::::::::::::
CCDS44 KTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV
1560 1570 1580 1590 1600 1610
1670 1680 1690 1700 1710 1720
pF1KE2 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDL
1620 1630 1640 1650 1660 1670
1730 1740 1750 1760 1770 1780
pF1KE2 TAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKA
1680 1690 1700 1710 1720 1730
1790 1800 1810 1820 1830 1840
pF1KE2 GSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEG
1740 1750 1760 1770 1780 1790
1850 1860 1870 1880 1890 1900
pF1KE2 HGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSL
1800 1810 1820 1830 1840 1850
1910 1920 1930 1940 1950 1960
pF1KE2 LSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGD
1860 1870 1880 1890 1900 1910
1970 1980 1990 2000 2010 2020
pF1KE2 ISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLR
1920 1930 1940 1950 1960 1970
2030 2040 2050 2060 2070 2080
pF1KE2 LEGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSA
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
CCDS44 LEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSA
1980 1990 2000 2010 2020 2030
2090 2100 2110 2120 2130 2140
pF1KE2 SSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGA
2040 2050 2060 2070 2080 2090
2150 2160 2170 2180
pF1KE2 LLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
2100 2110 2120 2130 2140
>>CCDS44795.1 CACNA1C gene_id:775|Hs108|chr12 (2146 aa)
initn: 10197 init1: 6296 opt: 6304 Z-score: 5245.1 bits: 984.3 E(32554): 0
Smith-Waterman score: 13900; 96.4% identity (96.5% similar) in 2205 aa overlap (1-2186:1-2146)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
:::::::::::::::::::::::::::: :::::::::::::::::
CCDS44 ----HYFCDAWNTFDALIVVGSIVDIAITEVN-----------NAEENSRISITFFRLFR
1280 1290 1300 1310 1320
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1330 1340 1350 1360 1370 1380
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1390 1400 1410 1420 1430 1440
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1450 1460 1470 1480 1490 1500
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1510 1520 1530 1540 1550 1560
1630 1640 1650 1660
pF1KE2 KTE-------------------GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV
::: ::::::::::::::::::::::::::::::::::::::
CCDS44 KTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV
1570 1580 1590 1600 1610 1620
1670 1680 1690 1700 1710 1720
pF1KE2 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDL
1630 1640 1650 1660 1670 1680
1730 1740 1750 1760 1770 1780
pF1KE2 TAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKA
1690 1700 1710 1720 1730 1740
1790 1800 1810 1820 1830 1840
pF1KE2 GSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEG
1750 1760 1770 1780 1790 1800
1850 1860 1870 1880 1890 1900
pF1KE2 HGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSL
1810 1820 1830 1840 1850 1860
1910 1920 1930 1940 1950 1960
pF1KE2 LSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGD
1870 1880 1890 1900 1910 1920
1970 1980 1990 2000 2010 2020
pF1KE2 ISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLR
1930 1940 1950 1960 1970 1980
2030 2040 2050 2060 2070 2080
pF1KE2 LEGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSA
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
CCDS44 LEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSA
1990 2000 2010 2020 2030 2040
2090 2100 2110 2120 2130 2140
pF1KE2 SSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGA
2050 2060 2070 2080 2090 2100
2150 2160 2170 2180
pF1KE2 LLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
2110 2120 2130 2140
>>CCDS44793.1 CACNA1C gene_id:775|Hs108|chr12 (2157 aa)
initn: 10013 init1: 6296 opt: 6304 Z-score: 5245.1 bits: 984.3 E(32554): 0
Smith-Waterman score: 14015; 96.9% identity (97.0% similar) in 2205 aa overlap (1-2186:1-2157)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
CCDS44 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660
pF1KE2 KTE-------------------GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV
::: ::::::::::::::::::::::::::::::::::::::
CCDS44 KTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV
1580 1590 1600 1610 1620 1630
1670 1680 1690 1700 1710 1720
pF1KE2 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDL
1640 1650 1660 1670 1680 1690
1730 1740 1750 1760 1770 1780
pF1KE2 TAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 TAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKA
1700 1710 1720 1730 1740 1750
1790 1800 1810 1820 1830 1840
pF1KE2 GSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEG
1760 1770 1780 1790 1800 1810
1850 1860 1870 1880 1890 1900
pF1KE2 HGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 HGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSL
1820 1830 1840 1850 1860 1870
1910 1920 1930 1940 1950 1960
pF1KE2 LSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGD
1880 1890 1900 1910 1920 1930
1970 1980 1990 2000 2010 2020
pF1KE2 ISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLR
1940 1950 1960 1970 1980 1990
2030 2040 2050 2060 2070 2080
pF1KE2 LEGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSA
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
CCDS44 LEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSA
2000 2010 2020 2030 2040 2050
2090 2100 2110 2120 2130 2140
pF1KE2 SSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGA
2060 2070 2080 2090 2100 2110
2150 2160 2170 2180
pF1KE2 LLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS44 LLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
2120 2130 2140 2150
>>CCDS53735.1 CACNA1C gene_id:775|Hs108|chr12 (2157 aa)
initn: 10013 init1: 6296 opt: 6304 Z-score: 5245.1 bits: 984.3 E(32554): 0
Smith-Waterman score: 14013; 96.9% identity (97.0% similar) in 2205 aa overlap (1-2186:1-2157)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
:::: ::::::::::::::::::::::::::::
CCDS53 SETN----------------------------PAEHTQCSPSMNAEENSRISITFFRLFR
1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660
pF1KE2 KTE-------------------GNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV
::: ::::::::::::::::::::::::::::::::::::::
CCDS53 KTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEV
1580 1590 1600 1610 1620 1630
1670 1680 1690 1700 1710 1720
pF1KE2 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 TVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDL
1640 1650 1660 1670 1680 1690
1730 1740 1750 1760 1770 1780
pF1KE2 TAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 TAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKA
1700 1710 1720 1730 1740 1750
1790 1800 1810 1820 1830 1840
pF1KE2 GSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 GSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEG
1760 1770 1780 1790 1800 1810
1850 1860 1870 1880 1890 1900
pF1KE2 HGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 HGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSL
1820 1830 1840 1850 1860 1870
1910 1920 1930 1940 1950 1960
pF1KE2 LSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 LSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGD
1880 1890 1900 1910 1920 1930
1970 1980 1990 2000 2010 2020
pF1KE2 ISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 ISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLR
1940 1950 1960 1970 1980 1990
2030 2040 2050 2060 2070 2080
pF1KE2 LEGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSA
::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
CCDS53 LEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSA
2000 2010 2020 2030 2040 2050
2090 2100 2110 2120 2130 2140
pF1KE2 SSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 SSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGA
2060 2070 2080 2090 2100 2110
2150 2160 2170 2180
pF1KE2 LLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
:::::::::::::::::::::::::::::::::::::::::::::
CCDS53 LLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
2120 2130 2140 2150
2186 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:18:25 2016 done: Tue Nov 8 17:18:26 2016
Total Scan time: 6.720 Total Display time: 1.850
Function used was FASTA [36.3.4 Apr, 2011]