Result of FASTA (omim) for
pF1KE2617
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2617, 2186 aa
1>>>pF1KE2617 2186 - 2186 aa - 2186 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1060+/-0.000458; mu= 12.8079+/- 0.029
mean_var=163.4368+/-34.665, 0's: 0 Z-trim(115.2): 275 B-trim: 1522 in 1/50
Lambda= 0.100323
statistics sampled from 25137 (25439) to 25137 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.298), width: 16
Scan time: 13.070
The best scores are: opt bits E(85289)
NP_001123299 (OMIM: 114205,601005,611875) voltage- (2186) 14485 2110.4 0
NP_955630 (OMIM: 114205,601005,611875) voltage-dep (2221) 12318 1796.7 0
NP_001123301 (OMIM: 114205,601005,611875) voltage- (2179) 9787 1430.4 0
NP_001123304 (OMIM: 114205,601005,611875) voltage- (2158) 8679 1270.0 0
XP_016875419 (OMIM: 114205,601005,611875) PREDICTE (2287) 8241 1206.7 0
NP_001123303 (OMIM: 114205,601005,611875) voltage- (2166) 8191 1199.4 0
XP_016875422 (OMIM: 114205,601005,611875) PREDICTE (2222) 8191 1199.4 0
XP_016875418 (OMIM: 114205,601005,611875) PREDICTE (2287) 8191 1199.4 0
NP_000710 (OMIM: 114205,601005,611875) voltage-dep (2138) 6304 926.3 0
NP_001123314 (OMIM: 114205,601005,611875) voltage- (2138) 6304 926.3 0
NP_001123311 (OMIM: 114205,601005,611875) voltage- (2144) 6304 926.3 0
NP_001123309 (OMIM: 114205,601005,611875) voltage- (2146) 6304 926.3 0
NP_001123306 (OMIM: 114205,601005,611875) voltage- (2157) 6304 926.3 0
NP_001123305 (OMIM: 114205,601005,611875) voltage- (2157) 6304 926.3 0
NP_001123308 (OMIM: 114205,601005,611875) voltage- (2155) 6277 922.4 0
NP_001123318 (OMIM: 114205,601005,611875) voltage- (2127) 6253 918.9 0
NP_001123313 (OMIM: 114205,601005,611875) voltage- (2138) 6253 918.9 0
NP_001123315 (OMIM: 114205,601005,611875) voltage- (2138) 6253 918.9 0
NP_001123310 (OMIM: 114205,601005,611875) voltage- (2146) 6253 918.9 0
NP_001123307 (OMIM: 114205,601005,611875) voltage- (2157) 6253 918.9 0
NP_001123302 (OMIM: 114205,601005,611875) voltage- (2173) 6253 918.9 0
NP_001161095 (OMIM: 114205,601005,611875) voltage- (2138) 6248 918.2 0
NP_001161096 (OMIM: 114205,601005,611875) voltage- (2173) 6248 918.2 0
NP_001161097 (OMIM: 114205,601005,611875) voltage- (2198) 6248 918.2 0
NP_001123312 (OMIM: 114205,601005,611875) voltage- (2138) 6197 910.8 0
XP_016875433 (OMIM: 114205,601005,611875) PREDICTE (2194) 6186 909.2 0
XP_016875431 (OMIM: 114205,601005,611875) PREDICTE (2194) 6186 909.2 0
XP_016875430 (OMIM: 114205,601005,611875) PREDICTE (2200) 6186 909.2 0
XP_016875425 (OMIM: 114205,601005,611875) PREDICTE (2213) 6186 909.2 0
XP_016875426 (OMIM: 114205,601005,611875) PREDICTE (2213) 6186 909.2 0
XP_016875428 (OMIM: 114205,601005,611875) PREDICTE (2211) 6159 905.3 0
XP_016875443 (OMIM: 114205,601005,611875) PREDICTE (2168) 6138 902.3 0
XP_006719080 (OMIM: 114205,601005,611875) PREDICTE (2168) 6138 902.3 0
XP_016875441 (OMIM: 114205,601005,611875) PREDICTE (2183) 6135 901.8 0
XP_016875437 (OMIM: 114205,601005,611875) PREDICTE (2194) 6135 901.8 0
XP_016875434 (OMIM: 114205,601005,611875) PREDICTE (2194) 6135 901.8 0
XP_016875429 (OMIM: 114205,601005,611875) PREDICTE (2202) 6135 901.8 0
XP_016875427 (OMIM: 114205,601005,611875) PREDICTE (2213) 6135 901.8 0
XP_016875432 (OMIM: 114205,601005,611875) PREDICTE (2194) 6130 901.1 0
XP_016875435 (OMIM: 114205,601005,611875) PREDICTE (2194) 6130 901.1 0
XP_016875421 (OMIM: 114205,601005,611875) PREDICTE (2254) 6130 901.1 0
XP_016875442 (OMIM: 114205,601005,611875) PREDICTE (2168) 6087 894.9 0
XP_016875439 (OMIM: 114205,601005,611875) PREDICTE (2192) 6079 893.7 0
XP_016875438 (OMIM: 114205,601005,611875) PREDICTE (2194) 6079 893.7 0
XP_016875436 (OMIM: 114205,601005,611875) PREDICTE (2194) 6079 893.7 0
XP_011519325 (OMIM: 114205,601005,611875) PREDICTE (2163) 5761 847.7 0
XP_016875424 (OMIM: 114205,601005,611875) PREDICTE (2219) 5761 847.7 0
XP_016875444 (OMIM: 114205,601005,611875) PREDICTE (2219) 5761 847.7 0
XP_016875420 (OMIM: 114205,601005,611875) PREDICTE (2259) 5761 847.7 0
NP_001123316 (OMIM: 114205,601005,611875) voltage- (2135) 5696 838.3 0
>>NP_001123299 (OMIM: 114205,601005,611875) voltage-depe (2186 aa)
initn: 14485 init1: 14485 opt: 14485 Z-score: 11331.0 bits: 2110.4 E(85289): 0
Smith-Waterman score: 14485; 100.0% identity (100.0% similar) in 2186 aa overlap (1-2186:1-2186)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2110 2120 2130 2140 2150 2160
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
NP_001 DAGCVRARGRPSEEELQDSRVYVSSL
2170 2180
>>NP_955630 (OMIM: 114205,601005,611875) voltage-depende (2221 aa)
initn: 12318 init1: 12318 opt: 12318 Z-score: 9635.9 bits: 1796.7 E(85289): 0
Smith-Waterman score: 14390; 98.4% identity (98.4% similar) in 2218 aa overlap (1-2183:1-2218)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1810 1820 1830 1840 1850 1860
1870 1880
pF1KE2 SNR-----------------------------------CHSRESQAAMAGQEETSQDETY
::: ::::::::::::::::::::::
NP_955 SNRERHVPMCEDLELRRDSGSAGTQAHCLLLRRANPSRCHSRESQAAMAGQEETSQDETY
1870 1880 1890 1900 1910 1920
1890 1900 1910 1920 1930 1940
pF1KE2 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 EVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRA
1930 1940 1950 1960 1970 1980
1950 1960 1970 1980 1990 2000
pF1KE2 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPA
1990 2000 2010 2020 2030 2040
2010 2020 2030 2040 2050 2060
pF1KE2 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRVRPVSLM
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
NP_955 TPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLM
2050 2060 2070 2080 2090 2100
2070 2080 2090 2100 2110 2120
pF1KE2 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESA
2110 2120 2130 2140 2150 2160
2130 2140 2150 2160 2170 2180
pF1KE2 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 ADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSS
2170 2180 2190 2200 2210 2220
pF1KE2 L
NP_955 L
>>NP_001123301 (OMIM: 114205,601005,611875) voltage-depe (2179 aa)
initn: 10271 init1: 6296 opt: 9787 Z-score: 7656.2 bits: 1430.4 E(85289): 0
Smith-Waterman score: 13961; 96.0% identity (96.0% similar) in 2227 aa overlap (1-2186:1-2179)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
NP_001 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1250 1260 1270
1330 1340 1350 1360
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSM-----------------
:::::::::::::::::::::::::::::::::::::::
NP_001 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMGPSCSHPPLAVLTAPPV
1280 1290 1300 1310 1320 1330
1370 1380 1390 1400 1410
pF1KE2 -----NAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADGFQNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVML
1340 1350 1360 1370 1380 1390
1420 1430 1440 1450 1460 1470
pF1KE2 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKK
1400 1410 1420 1430 1440 1450
1480 1490 1500 1510 1520 1530
pF1KE2 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILG
1460 1470 1480 1490 1500 1510
1540 1550 1560 1570 1580 1590
pF1KE2 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPL
1520 1530 1540 1550 1560 1570
1600 1610 1620 1630
pF1KE2 NSDGTVMFNATLFALVRTALRIKTE-------------------GNLEQANEELRAIIKK
::::::::::::::::::::::::: ::::::::::::::::
NP_001 NSDGTVMFNATLFALVRTALRIKTEEGPSPSEAHQGAEDPFRPAGNLEQANEELRAIIKK
1580 1590 1600 1610 1620 1630
1640 1650 1660 1670 1680 1690
pF1KE2 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSL
1640 1650 1660 1670 1680 1690
1700 1710 1720 1730 1740 1750
pF1KE2 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQ
1700 1710 1720 1730 1740 1750
1760 1770 1780 1790 1800 1810
pF1KE2 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNAN
1760 1770 1780 1790 1800 1810
1820 1830 1840 1850 1860 1870
pF1KE2 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEET
1820 1830 1840 1850 1860 1870
1880 1890 1900 1910 1920 1930
pF1KE2 SQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSA
1880 1890 1900 1910 1920 1930
1940 1950 1960 1970 1980 1990
pF1KE2 SLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRP
1940 1950 1960 1970 1980 1990
2000 2010 2020 2030 2040 2050
pF1KE2 FATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRV
::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
NP_001 FATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRV
2000 2010 2020 2030 2040 2050
2060 2070 2080 2090 2100 2110
pF1KE2 RPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTI
2060 2070 2080 2090 2100 2110
2120 2130 2140 2150 2160 2170
pF1KE2 EEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDS
2120 2130 2140 2150 2160 2170
2180
pF1KE2 RVYVSSL
:::::::
NP_001 RVYVSSL
>>NP_001123304 (OMIM: 114205,601005,611875) voltage-depe (2158 aa)
initn: 8678 init1: 8678 opt: 8679 Z-score: 6789.6 bits: 1270.0 E(85289): 0
Smith-Waterman score: 14232; 98.7% identity (98.7% similar) in 2186 aa overlap (1-2186:1-2158)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
NP_001 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1780 1790 1800 1810 1820 1830
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1840 1850 1860 1870 1880 1890
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2020 2030 2040 2050 2060 2070
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2080 2090 2100 2110 2120 2130
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
NP_001 DAGCVRARGRPSEEELQDSRVYVSSL
2140 2150
>>XP_016875419 (OMIM: 114205,601005,611875) PREDICTED: v (2287 aa)
initn: 11169 init1: 8194 opt: 8241 Z-score: 6446.6 bits: 1206.7 E(85289): 0
Smith-Waterman score: 14041; 96.1% identity (96.2% similar) in 2234 aa overlap (18-2186:74-2287)
10 20 30 40
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPG
::::::::::::::::::::::::::::::
XP_016 SPGESPVRTSSVQTPSHPTSTEPCGPPTLCSNYGSPRPAHANMNANAAAGLAPEHIPTPG
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE2 AALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCL
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE2 TLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFL
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE2 IIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGK
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE2 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE2 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFD
350 360 370 380 390 400
350 360 370 380 390 400
pF1KE2 NFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGE
410 420 430 440 450 460
410 420 430 440 450 460
pF1KE2 FSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRN----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNRGTP
470 480 490 500 510 520
470 480 490
pF1KE2 ---------------------MSMPTSETESVNTENVAGGDIEGENCGARLA--------
.::::::::::::::::::::::::::::::
XP_016 AGMLDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAKGSRSAVE
530 540 550 560 570 580
500 510 520
pF1KE2 --------------------------------HRISKSKFSRYWRRWNRFCRRKCRAAVK
::::::::::::::::::::::::::::
XP_016 PAVLLPWGVTTVNSPWPLEELQTEALSQTSPSHRISKSKFSRYWRRWNRFCRRKCRAAVK
590 600 610 620 630 640
530 540 550 560 570 580
pF1KE2 SNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQA
650 660 670 680 690 700
590 600 610 620 630 640
pF1KE2 YFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVA
710 720 730 740 750 760
650 660 670 680 690 700
pF1KE2 SLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQI
770 780 790 800 810 820
710 720 730 740 750 760
pF1KE2 LTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESL
830 840 850 860 870 880
770 780 790 800 810 820
pF1KE2 TSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKIN
890 900 910 920 930 940
830 840 850 860 870 880
pF1KE2 MDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFI
950 960 970 980 990 1000
890 900 910 920 930 940
pF1KE2 FSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTT
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHIL---------
1010 1020 1030 1040 1050
950 960 970 980 990 1000
pF1KE2 IFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -----------GNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI
1060 1070 1080 1090 1100
1010 1020 1030 1040 1050 1060
pF1KE2 SFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFM
1110 1120 1130 1140 1150 1160
1070 1080 1090 1100 1110 1120
pF1KE2 FACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVL
1170 1180 1190 1200 1210 1220
1130 1140 1150 1160 1170 1180
pF1KE2 AAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFV
1230 1240 1250 1260 1270 1280
1190 1200 1210 1220 1230 1240
pF1KE2 GFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFE
1290 1300 1310 1320 1330 1340
1250 1260 1270 1280 1290 1300
pF1KE2 YLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDP
1350 1360 1370 1380 1390 1400
1310 1320 1330 1340 1350 1360
pF1KE2 WNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS
1410 1420 1430 1440 1450 1460
1370 1380 1390 1400 1410 1420
pF1KE2 MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY
1470 1480 1490 1500 1510 1520
1430 1440 1450 1460 1470 1480
pF1KE2 AVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE
1530 1540 1550 1560 1570 1580
1490 1500 1510 1520 1530 1540
pF1KE2 SEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHL
1590 1600 1610 1620 1630 1640
1550 1560 1570 1580 1590 1600
pF1KE2 DEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDG
1650 1660 1670 1680 1690 1700
1610 1620 1630 1640 1650 1660
pF1KE2 TVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVT
1710 1720 1730 1740 1750 1760
1670 1680 1690 1700 1710 1720
pF1KE2 VGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLT
1770 1780 1790 1800 1810 1820
1730 1740 1750 1760 1770 1780
pF1KE2 AEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG
1830 1840 1850 1860 1870 1880
1790 1800 1810 1820 1830 1840
pF1KE2 SSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGH
1890 1900 1910 1920 1930 1940
1850 1860 1870 1880 1890 1900
pF1KE2 GPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLL
1950 1960 1970 1980 1990 2000
1910 1920 1930 1940 1950 1960
pF1KE2 STEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDI
2010 2020 2030 2040 2050 2060
1970 1980 1990 2000 2010 2020
pF1KE2 SQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRL
2070 2080 2090 2100 2110 2120
2030 2040 2050 2060 2070 2080
pF1KE2 EGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSAS
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 EGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSAS
2130 2140 2150 2160 2170 2180
2090 2100 2110 2120 2130 2140
pF1KE2 SLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGAL
2190 2200 2210 2220 2230 2240
2150 2160 2170 2180
pF1KE2 LPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
2250 2260 2270 2280
>>NP_001123303 (OMIM: 114205,601005,611875) voltage-depe (2166 aa)
initn: 8144 init1: 8144 opt: 8191 Z-score: 6407.8 bits: 1199.4 E(85289): 0
Smith-Waterman score: 14316; 99.0% identity (99.1% similar) in 2186 aa overlap (1-2186:1-2166)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2090 2100 2110 2120 2130 2140
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
NP_001 DAGCVRARGRPSEEELQDSRVYVSSL
2150 2160
>>XP_016875422 (OMIM: 114205,601005,611875) PREDICTED: v (2222 aa)
initn: 8144 init1: 8144 opt: 8191 Z-score: 6407.7 bits: 1199.4 E(85289): 0
Smith-Waterman score: 14198; 99.0% identity (99.1% similar) in 2169 aa overlap (18-2186:74-2222)
10 20 30 40
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPG
::::::::::::::::::::::::::::::
XP_016 SPGESPVRTSSVQTPSHPTSTEPCGPPTLCSNYGSPRPAHANMNANAAAGLAPEHIPTPG
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE2 AALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCL
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE2 TLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFL
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE2 IIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGK
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE2 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE2 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFD
350 360 370 380 390 400
350 360 370 380 390 400
pF1KE2 NFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGE
410 420 430 440 450 460
410 420 430 440 450 460
pF1KE2 FSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMP
470 480 490 500 510 520
470 480 490 500 510 520
pF1KE2 TSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFY
530 540 550 560 570 580
530 540 550 560 570 580
pF1KE2 WLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSL
590 600 610 620 630 640
590 600 610 620 630 640
pF1KE2 FNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNS
650 660 670 680 690 700
650 660 670 680 690 700
pF1KE2 VRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGED
710 720 730 740 750 760
710 720 730 740 750 760
pF1KE2 WNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQK
770 780 790 800 810 820
770 780 790 800 810 820
pF1KE2 EEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQ
830 840 850 860 870 880
830 840 850 860 870 880
pF1KE2 PNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNN
890 900 910 920 930 940
890 900 910 920 930 940
pF1KE2 RFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIE
950 960 970 980 990 1000
950 960 970 980 990 1000
pF1KE2 IALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQ
:::: ::::::::::::::::::::::::::::::::::::
XP_016 IALK--------------------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQ
1010 1020 1030 1040
1010 1020 1030 1040 1050 1060
pF1KE2 SSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIG
1050 1060 1070 1080 1090 1100
1070 1080 1090 1100 1110 1120
pF1KE2 VQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMA
1110 1120 1130 1140 1150 1160
1130 1140 1150 1160 1170 1180
pF1KE2 LFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIV
1170 1180 1190 1200 1210 1220
1190 1200 1210 1220 1230 1240
pF1KE2 TFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFV
1230 1240 1250 1260 1270 1280
1250 1260 1270 1280 1290 1300
pF1KE2 LILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFD
1290 1300 1310 1320 1330 1340
1310 1320 1330 1340 1350 1360
pF1KE2 FLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEE
1350 1360 1370 1380 1390 1400
1370 1380 1390 1400 1410 1420
pF1KE2 NSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGM
1410 1420 1430 1440 1450 1460
1430 1440 1450 1460 1470 1480
pF1KE2 QVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSN
1470 1480 1490 1500 1510 1520
1490 1500 1510 1520 1530 1540
pF1KE2 STEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKR
1530 1540 1550 1560 1570 1580
1550 1560 1570 1580 1590 1600
pF1KE2 IWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFN
1590 1600 1610 1620 1630 1640
1610 1620 1630 1640 1650 1660
pF1KE2 ATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFY
1650 1660 1670 1680 1690 1700
1670 1680 1690 1700 1710 1720
pF1KE2 ATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEEL
1710 1720 1730 1740 1750 1760
1730 1740 1750 1760 1770 1780
pF1KE2 DKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGD
1770 1780 1790 1800 1810 1820
1790 1800 1810 1820 1830 1840
pF1KE2 TESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLS
1830 1840 1850 1860 1870 1880
1850 1860 1870 1880 1890 1900
pF1KE2 PAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEML
1890 1900 1910 1920 1930 1940
1910 1920 1930 1940 1950 1960
pF1KE2 SYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTV
1950 1960 1970 1980 1990 2000
1970 1980 1990 2000 2010 2020
pF1KE2 LPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVES
2010 2020 2030 2040 2050 2060
2030 2040 2050 2060 2070 2080
pF1KE2 SEKLNSSFPSIHCGSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEA
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
XP_016 SEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEA
2070 2080 2090 2100 2110 2120
2090 2100 2110 2120 2130 2140
pF1KE2 VLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVN
2130 2140 2150 2160 2170 2180
2150 2160 2170 2180
pF1KE2 CRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
:::::::::::::::::::::::::::::::::::::::
XP_016 CRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
2190 2200 2210 2220
>>XP_016875418 (OMIM: 114205,601005,611875) PREDICTED: v (2287 aa)
initn: 11119 init1: 8144 opt: 8191 Z-score: 6407.5 bits: 1199.4 E(85289): 0
Smith-Waterman score: 14042; 96.1% identity (96.2% similar) in 2234 aa overlap (18-2186:74-2287)
10 20 30 40
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPG
::::::::::::::::::::::::::::::
XP_016 SPGESPVRTSSVQTPSHPTSTEPCGPPTLCSNYGSPRPAHANMNANAAAGLAPEHIPTPG
50 60 70 80 90 100
50 60 70 80 90 100
pF1KE2 AALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCL
110 120 130 140 150 160
110 120 130 140 150 160
pF1KE2 TLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFL
170 180 190 200 210 220
170 180 190 200 210 220
pF1KE2 IIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGK
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE2 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGL
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE2 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFD
350 360 370 380 390 400
350 360 370 380 390 400
pF1KE2 NFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFAFAMLTVFQCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGE
410 420 430 440 450 460
410 420 430 440 450 460
pF1KE2 FSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRN----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNRGTP
470 480 490 500 510 520
470 480 490
pF1KE2 ---------------------MSMPTSETESVNTENVAGGDIEGENCGARLA--------
.::::::::::::::::::::::::::::::
XP_016 AGMLDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAKGSRSAVE
530 540 550 560 570 580
500 510 520
pF1KE2 --------------------------------HRISKSKFSRYWRRWNRFCRRKCRAAVK
::::::::::::::::::::::::::::
XP_016 PAVLLPWGVTTVNSPWPLEELQTEALSQTSPSHRISKSKFSRYWRRWNRFCRRKCRAAVK
590 600 610 620 630 640
530 540 550 560 570 580
pF1KE2 SNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNVFYWLVIFLVFLNTLTIASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQA
650 660 670 680 690 700
590 600 610 620 630 640
pF1KE2 YFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFVSLFNRFDCFVVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVA
710 720 730 740 750 760
650 660 670 680 690 700
pF1KE2 SLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQI
770 780 790 800 810 820
710 720 730 740 750 760
pF1KE2 LTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESL
830 840 850 860 870 880
770 780 790 800 810 820
pF1KE2 TSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSAQKEEEEEKERKKLARTASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKIN
890 900 910 920 930 940
830 840 850 860 870 880
pF1KE2 MDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDDLQPNENEDKSPYPNPETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFI
950 960 970 980 990 1000
890 900 910 920 930 940
pF1KE2 FSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSSNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTT
1010 1020 1030 1040 1050 1060
950 960 970 980 990 1000
pF1KE2 IFTIEIALKILGNADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLI
::::::::: :::::::::::::::::::::::::::::::
XP_016 IFTIEIALK--------------------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLI
1070 1080 1090 1100
1010 1020 1030 1040 1050 1060
pF1KE2 SFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFM
1110 1120 1130 1140 1150 1160
1070 1080 1090 1100 1110 1120
pF1KE2 FACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVL
1170 1180 1190 1200 1210 1220
1130 1140 1150 1160 1170 1180
pF1KE2 AAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAMMALFTVSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFV
1230 1240 1250 1260 1270 1280
1190 1200 1210 1220 1230 1240
pF1KE2 GFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFE
1290 1300 1310 1320 1330 1340
1250 1260 1270 1280 1290 1300
pF1KE2 YLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDP
1350 1360 1370 1380 1390 1400
1310 1320 1330 1340 1350 1360
pF1KE2 WNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPS
1410 1420 1430 1440 1450 1460
1370 1380 1390 1400 1410 1420
pF1KE2 MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIY
1470 1480 1490 1500 1510 1520
1430 1440 1450 1460 1470 1480
pF1KE2 AVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPE
1530 1540 1550 1560 1570 1580
1490 1500 1510 1520 1530 1540
pF1KE2 SEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHL
1590 1600 1610 1620 1630 1640
1550 1560 1570 1580 1590 1600
pF1KE2 DEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDG
1650 1660 1670 1680 1690 1700
1610 1620 1630 1640 1650 1660
pF1KE2 TVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVT
1710 1720 1730 1740 1750 1760
1670 1680 1690 1700 1710 1720
pF1KE2 VGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLT
1770 1780 1790 1800 1810 1820
1730 1740 1750 1760 1770 1780
pF1KE2 AEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAG
1830 1840 1850 1860 1870 1880
1790 1800 1810 1820 1830 1840
pF1KE2 SSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGH
1890 1900 1910 1920 1930 1940
1850 1860 1870 1880 1890 1900
pF1KE2 GPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPPLSPAIRVQEVAWKLSSNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLL
1950 1960 1970 1980 1990 2000
1910 1920 1930 1940 1950 1960
pF1KE2 STEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDI
2010 2020 2030 2040 2050 2060
1970 1980 1990 2000 2010 2020
pF1KE2 SQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRL
2070 2080 2090 2100 2110 2120
2030 2040 2050 2060 2070 2080
pF1KE2 EGVESSEKLNSSFPSIHCGSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSAS
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_016 EGVESSEKLNSSFPSIHCGSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSAS
2130 2140 2150 2160 2170 2180
2090 2100 2110 2120 2130 2140
pF1KE2 SLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGAL
2190 2200 2210 2220 2230 2240
2150 2160 2170 2180
pF1KE2 LPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPFVNCRDAGQDRAGGEEDAGCVRARGRPSEEELQDSRVYVSSL
2250 2260 2270 2280
>>NP_000710 (OMIM: 114205,601005,611875) voltage-depende (2138 aa)
initn: 12026 init1: 6296 opt: 6304 Z-score: 4931.9 bits: 926.3 E(85289): 0
Smith-Waterman score: 14063; 97.8% identity (97.8% similar) in 2186 aa overlap (1-2186:1-2138)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::
NP_000 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPK------------------------
1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ----HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1580 1590 1600 1610 1620 1630
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1640 1650 1660 1670 1680 1690
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1700 1710 1720 1730 1740 1750
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1760 1770 1780 1790 1800 1810
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1820 1830 1840 1850 1860 1870
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1880 1890 1900 1910 1920 1930
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1940 1950 1960 1970 1980 1990
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2000 2010 2020 2030 2040 2050
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2060 2070 2080 2090 2100 2110
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
NP_000 DAGCVRARGRPSEEELQDSRVYVSSL
2120 2130
>>NP_001123314 (OMIM: 114205,601005,611875) voltage-depe (2138 aa)
initn: 11963 init1: 6296 opt: 6304 Z-score: 4931.9 bits: 926.3 E(85289): 0
Smith-Waterman score: 14061; 97.8% identity (97.8% similar) in 2186 aa overlap (1-2186:1-2138)
10 20 30 40 50 60
pF1KE2 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IASEHYNQPNWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TASPEKKQELVEKPAVGESKEEKIELKSITADGESPPATKINMDDLQPNENEDKSPYPNP
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVF
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALK---------
910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE2 TSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -----------MTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVL
960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSD
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPEL
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNC
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQH
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVIL
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE2 SETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEENSRISITFFRLFR
:::: ::::::::::::::::::::::::::::
NP_001 SETN----------------------------PAEHTQCSPSMNAEENSRISITFFRLFR
1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE2 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KE2 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 INRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFA
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KE2 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRI
1460 1470 1480 1490 1500 1510
1570 1580 1590 1600 1610 1620
pF1KE2 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRI
1520 1530 1540 1550 1560 1570
1630 1640 1650 1660 1670 1680
pF1KE2 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFK
1580 1590 1600 1610 1620 1630
1690 1700 1710 1720 1730 1740
pF1KE2 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASE
1640 1650 1660 1670 1680 1690
1750 1760 1770 1780 1790 1800
pF1KE2 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDIFRRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGSSQGDTESPSHEKLVDST
1700 1710 1720 1730 1740 1750
1810 1820 1830 1840 1850 1860
pF1KE2 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTPSSYSSTGSNANINNANNTALGRLPRPAGYPSTVSTVEGHGPPLSPAIRVQEVAWKLS
1760 1770 1780 1790 1800 1810
1870 1880 1890 1900 1910 1920
pF1KE2 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNRCHSRESQAAMAGQEETSQDETYEVKMNHDTEACSEPSLLSTEMLSYQDDENRQLTLP
1820 1830 1840 1850 1860 1870
1930 1940 1950 1960 1970 1980
pF1KE2 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKDRGGDISQKTVLPLHLVHHQALAV
1880 1890 1900 1910 1920 1930
1990 2000 2010 2020 2030 2040
pF1KE2 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGLSPLLQRSHSPASFPRPFATPPATPGSRGWPPQPVPTLRLEGVESSEKLNSSFPSIHC
1940 1950 1960 1970 1980 1990
2050 2060 2070 2080 2090 2100
pF1KE2 GSWVETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSWAETTPGGGGSSAARRVRPVSLMVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQD
2000 2010 2020 2030 2040 2050
2110 2120 2130 2140 2150 2160
pF1KE2 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKFIEVTTQELADACDMTIEEMESAADNILSGGAPQSPNGALLPFVNCRDAGQDRAGGEE
2060 2070 2080 2090 2100 2110
2170 2180
pF1KE2 DAGCVRARGRPSEEELQDSRVYVSSL
::::::::::::::::::::::::::
NP_001 DAGCVRARGRPSEEELQDSRVYVSSL
2120 2130
2186 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:18:26 2016 done: Tue Nov 8 17:18:29 2016
Total Scan time: 13.070 Total Display time: 1.610
Function used was FASTA [36.3.4 Apr, 2011]