FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2618, 393 aa 1>>>pF1KE2618 393 - 393 aa - 393 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1223+/-0.00081; mu= 9.1298+/- 0.049 mean_var=114.2234+/-22.193, 0's: 0 Z-trim(111.1): 30 B-trim: 10 in 1/52 Lambda= 0.120004 statistics sampled from 12103 (12132) to 12103 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.373), width: 16 Scan time: 1.770 The best scores are: opt bits E(32554) CCDS46980.1 TP63 gene_id:8626|Hs108|chr3 ( 393) 2667 472.3 3.4e-133 CCDS46977.1 TP63 gene_id:8626|Hs108|chr3 ( 487) 2579 457.1 1.6e-128 CCDS46979.1 TP63 gene_id:8626|Hs108|chr3 ( 461) 2399 425.9 3.6e-119 CCDS46978.1 TP63 gene_id:8626|Hs108|chr3 ( 586) 2399 426.0 4.4e-119 CCDS46976.1 TP63 gene_id:8626|Hs108|chr3 ( 555) 2311 410.7 1.6e-114 CCDS3293.1 TP63 gene_id:8626|Hs108|chr3 ( 680) 2311 410.8 1.9e-114 CCDS82887.1 TP63 gene_id:8626|Hs108|chr3 ( 676) 2257 401.4 1.3e-111 CCDS44050.1 TP73 gene_id:7161|Hs108|chr1 ( 450) 1629 292.6 4.8e-79 CCDS44049.1 TP73 gene_id:7161|Hs108|chr1 ( 587) 1629 292.7 6e-79 CCDS44051.1 TP73 gene_id:7161|Hs108|chr1 ( 426) 1625 291.9 7.3e-79 CCDS55566.1 TP73 gene_id:7161|Hs108|chr1 ( 499) 1621 291.2 1.4e-78 CCDS55568.1 TP73 gene_id:7161|Hs108|chr1 ( 540) 1620 291.1 1.6e-78 CCDS49.1 TP73 gene_id:7161|Hs108|chr1 ( 636) 1621 291.3 1.7e-78 CCDS55567.1 TP73 gene_id:7161|Hs108|chr1 ( 555) 1617 290.6 2.4e-78 CCDS59965.1 TP73 gene_id:7161|Hs108|chr1 ( 403) 1614 290.0 2.6e-78 CCDS55569.1 TP73 gene_id:7161|Hs108|chr1 ( 565) 1612 289.7 4.4e-78 CCDS11118.1 TP53 gene_id:7157|Hs108|chr17 ( 393) 932 171.9 9e-43 CCDS73969.1 TP53 gene_id:7157|Hs108|chr17 ( 354) 927 171.0 1.5e-42 CCDS45606.1 TP53 gene_id:7157|Hs108|chr17 ( 341) 861 159.6 4e-39 CCDS45605.1 TP53 gene_id:7157|Hs108|chr17 ( 346) 861 159.6 4e-39 CCDS73971.1 TP53 gene_id:7157|Hs108|chr17 ( 302) 856 158.7 6.6e-39 CCDS73970.1 TP53 gene_id:7157|Hs108|chr17 ( 307) 856 158.7 6.6e-39 CCDS73966.1 TP53 gene_id:7157|Hs108|chr17 ( 261) 802 149.3 3.8e-36 CCDS73968.1 TP53 gene_id:7157|Hs108|chr17 ( 209) 731 137.0 1.6e-32 CCDS73967.1 TP53 gene_id:7157|Hs108|chr17 ( 214) 731 137.0 1.6e-32 CCDS73963.1 TP53 gene_id:7157|Hs108|chr17 ( 234) 682 128.5 6.2e-30 CCDS73965.1 TP53 gene_id:7157|Hs108|chr17 ( 182) 611 116.2 2.5e-26 CCDS73964.1 TP53 gene_id:7157|Hs108|chr17 ( 187) 611 116.2 2.6e-26 >>CCDS46980.1 TP63 gene_id:8626|Hs108|chr3 (393 aa) initn: 2667 init1: 2667 opt: 2667 Z-score: 2504.8 bits: 472.3 E(32554): 3.4e-133 Smith-Waterman score: 2667; 100.0% identity (100.0% similar) in 393 aa overlap (1-393:1-393) 10 20 30 40 50 60 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA 310 320 330 340 350 360 370 380 390 pF1KE2 CFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP ::::::::::::::::::::::::::::::::: CCDS46 CFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP 370 380 390 >>CCDS46977.1 TP63 gene_id:8626|Hs108|chr3 (487 aa) initn: 2579 init1: 2579 opt: 2579 Z-score: 2421.0 bits: 457.1 E(32554): 1.6e-128 Smith-Waterman score: 2579; 100.0% identity (100.0% similar) in 379 aa overlap (15-393:109-487) 10 20 30 40 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDH :::::::::::::::::::::::::::::: CCDS46 EPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDH 80 90 100 110 120 130 50 60 70 80 90 100 pF1KE2 AQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 AQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTEL 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE2 KKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQI 200 210 220 230 240 250 170 180 190 200 210 220 pF1KE2 APPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 APPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNR 260 270 280 290 300 310 230 240 250 260 270 280 pF1KE2 RPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPF 320 330 340 350 360 370 290 300 310 320 330 340 pF1KE2 RQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQ 380 390 400 410 420 430 350 360 370 380 390 pF1KE2 QQQQHQHLLQKHLLSACFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QQQQHQHLLQKHLLSACFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP 440 450 460 470 480 >>CCDS46979.1 TP63 gene_id:8626|Hs108|chr3 (461 aa) initn: 2500 init1: 2399 opt: 2399 Z-score: 2253.0 bits: 425.9 E(32554): 3.6e-119 Smith-Waterman score: 2399; 99.7% identity (100.0% similar) in 356 aa overlap (1-356:1-356) 10 20 30 40 50 60 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS46 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQ 310 320 330 340 350 360 370 380 390 pF1KE2 CFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP CCDS46 SPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAG 370 380 390 400 410 420 >>CCDS46978.1 TP63 gene_id:8626|Hs108|chr3 (586 aa) initn: 2528 init1: 2399 opt: 2399 Z-score: 2251.4 bits: 426.0 E(32554): 4.4e-119 Smith-Waterman score: 2399; 99.7% identity (100.0% similar) in 356 aa overlap (1-356:1-356) 10 20 30 40 50 60 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS46 SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQ 310 320 330 340 350 360 370 380 390 pF1KE2 CFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP CCDS46 SPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAG 370 380 390 400 410 420 >>CCDS46976.1 TP63 gene_id:8626|Hs108|chr3 (555 aa) initn: 2440 init1: 2311 opt: 2311 Z-score: 2169.4 bits: 410.7 E(32554): 1.6e-114 Smith-Waterman score: 2311; 99.7% identity (100.0% similar) in 342 aa overlap (15-356:109-450) 10 20 30 40 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDH :::::::::::::::::::::::::::::: CCDS46 EPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDH 80 90 100 110 120 130 50 60 70 80 90 100 pF1KE2 AQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 AQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTEL 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE2 KKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQI 200 210 220 230 240 250 170 180 190 200 210 220 pF1KE2 APPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 APPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNR 260 270 280 290 300 310 230 240 250 260 270 280 pF1KE2 RPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPF 320 330 340 350 360 370 290 300 310 320 330 340 pF1KE2 RQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 RQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQ 380 390 400 410 420 430 350 360 370 380 390 pF1KE2 QQQQHQHLLQKHLLSACFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP :::::::::::. CCDS46 QQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDG 440 450 460 470 480 490 >>CCDS3293.1 TP63 gene_id:8626|Hs108|chr3 (680 aa) initn: 2412 init1: 2311 opt: 2311 Z-score: 2168.0 bits: 410.8 E(32554): 1.9e-114 Smith-Waterman score: 2311; 99.7% identity (100.0% similar) in 342 aa overlap (15-356:109-450) 10 20 30 40 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDH :::::::::::::::::::::::::::::: CCDS32 EPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDH 80 90 100 110 120 130 50 60 70 80 90 100 pF1KE2 AQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTEL 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE2 KKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 KKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQI 200 210 220 230 240 250 170 180 190 200 210 220 pF1KE2 APPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 APPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNR 260 270 280 290 300 310 230 240 250 260 270 280 pF1KE2 RPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPF 320 330 340 350 360 370 290 300 310 320 330 340 pF1KE2 RQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQ 380 390 400 410 420 430 350 360 370 380 390 pF1KE2 QQQQHQHLLQKHLLSACFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP :::::::::::. CCDS32 QQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDG 440 450 460 470 480 490 >>CCDS82887.1 TP63 gene_id:8626|Hs108|chr3 (676 aa) initn: 2324 init1: 1799 opt: 2257 Z-score: 2117.5 bits: 401.4 E(32554): 1.3e-111 Smith-Waterman score: 2257; 98.2% identity (98.8% similar) in 342 aa overlap (15-356:109-446) 10 20 30 40 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDH :::::::::::::::::::::::::::::: CCDS82 EPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDH 80 90 100 110 120 130 50 60 70 80 90 100 pF1KE2 AQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 AQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTEL 140 150 160 170 180 190 110 120 130 140 150 160 pF1KE2 KKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQI 200 210 220 230 240 250 170 180 190 200 210 220 pF1KE2 APPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 APPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNR 260 270 280 290 300 310 230 240 250 260 270 280 pF1KE2 RPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPF ::::::::::::::::::::::::::::::::::::::::::::::::::::::. : CCDS82 RPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDA----F 320 330 340 350 360 370 290 300 310 320 330 340 pF1KE2 RQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 RQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQ 380 390 400 410 420 430 350 360 370 380 390 pF1KE2 QQQQHQHLLQKHLLSACFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP :::::::::::. CCDS82 QQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDG 440 450 460 470 480 490 >>CCDS44050.1 TP73 gene_id:7161|Hs108|chr1 (450 aa) initn: 1618 init1: 1325 opt: 1629 Z-score: 1532.6 bits: 292.6 E(32554): 4.8e-79 Smith-Waterman score: 1629; 68.4% identity (86.3% similar) in 358 aa overlap (1-352:1-353) 10 20 30 40 50 60 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS :::. . :. ... :. :: : ..::: ... ..:.:::. .:: :: . :::::::: CCDS44 MLYVGDPAR-HLATAQF-NL-LSSTMDQ-MSSRAASASPYTPEHAA-SVPTHSPYAQPSS 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK :::..::.:.::::::::::: :.:.::::::::::::::: ::::::::::::::::: CCDS44 TFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ : :::: :..::::::::::::::.::::::::::.:.::::: :: :::::::::. .: CCDS44 VSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV ::.::.::::::.::::::::::::::.::::::::::::::::::::::.::: ::::: CCDS44 YVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQV 180 190 200 210 220 230 250 260 270 280 290 pF1KE2 LGRRCFEARICACPGRDRKADEDSIRKQQVSD--STKNGDGTKRPFRQNTHGIQM--TSI :::: ::.::::::::::::::: :.::. . :.::: ..:: :.:. .. ... CCDS44 LGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE2 KKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQ--QQHQHLLQ :::: :.. :: :::::..:.:.:.:::::::. .:: ...:::::: :. .:: CCDS44 KKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQP 300 310 320 330 340 350 360 370 380 390 pF1KE2 KHLLSACFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP CCDS44 PSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANG 360 370 380 390 400 410 >>CCDS44049.1 TP73 gene_id:7161|Hs108|chr1 (587 aa) initn: 1618 init1: 1325 opt: 1629 Z-score: 1530.9 bits: 292.7 E(32554): 6e-79 Smith-Waterman score: 1629; 68.4% identity (86.3% similar) in 358 aa overlap (1-352:1-353) 10 20 30 40 50 60 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS :::. . :. ... :. :: : ..::: ... ..:.:::. .:: :: . :::::::: CCDS44 MLYVGDPAR-HLATAQF-NL-LSSTMDQ-MSSRAASASPYTPEHAA-SVPTHSPYAQPSS 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK :::..::.:.::::::::::: :.:.::::::::::::::: ::::::::::::::::: CCDS44 TFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ : :::: :..::::::::::::::.::::::::::.:.::::: :: :::::::::. .: CCDS44 VSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV ::.::.::::::.::::::::::::::.::::::::::::::::::::::.::: ::::: CCDS44 YVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQV 180 190 200 210 220 230 250 260 270 280 290 pF1KE2 LGRRCFEARICACPGRDRKADEDSIRKQQVSD--STKNGDGTKRPFRQNTHGIQM--TSI :::: ::.::::::::::::::: :.::. . :.::: ..:: :.:. .. ... CCDS44 LGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE2 KKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQ--QQHQHLLQ :::: :.. :: :::::..:.:.:.:::::::. .:: ...:::::: :. .:: CCDS44 KKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQP 300 310 320 330 340 350 360 370 380 390 pF1KE2 KHLLSACFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP CCDS44 PSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANG 360 370 380 390 400 410 >>CCDS44051.1 TP73 gene_id:7161|Hs108|chr1 (426 aa) initn: 1601 init1: 1325 opt: 1625 Z-score: 1529.3 bits: 291.9 E(32554): 7.3e-79 Smith-Waterman score: 1625; 64.2% identity (82.0% similar) in 394 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KE2 MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS :::. . :. ... :. :: : ..::: ... ..:.:::. .:: :: . :::::::: CCDS44 MLYVGDPAR-HLATAQF-NL-LSSTMDQ-MSSRAASASPYTPEHAA-SVPTHSPYAQPSS 10 20 30 40 50 70 80 90 100 110 120 pF1KE2 TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK :::..::.:.::::::::::: :.:.::::::::::::::: ::::::::::::::::: CCDS44 TFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KE2 VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ : :::: :..::::::::::::::.::::::::::.:.::::: :: :::::::::. .: CCDS44 VSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQ 120 130 140 150 160 170 190 200 210 220 230 240 pF1KE2 YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV ::.::.::::::.::::::::::::::.::::::::::::::::::::::.::: ::::: CCDS44 YVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQV 180 190 200 210 220 230 250 260 270 280 290 pF1KE2 LGRRCFEARICACPGRDRKADEDSIRKQQVSD--STKNGDGTKRPFRQNTHGIQM--TSI :::: ::.::::::::::::::: :.::. . :.::: ..:: :.:. .. ... CCDS44 LGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGV 240 250 260 270 280 290 300 310 320 330 340 350 pF1KE2 KKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQ--QQHQHLLQ :::: :.. :: :::::..:.:.:.:::::::. .:: ...:::::: :. . : CCDS44 KKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPPRDAQ 300 310 320 330 340 350 360 370 380 390 pF1KE2 KHL-LSACFRNELVEPRRETPKQSDVFFRHSKPPNRSVYP . :: : . .:.: : .. :: : CCDS44 QPWPRSASQRRDEQQPQR--PVHGLGVPLHSATPLPRRPQPRQFFNRIGVSKLHRVFHLP 360 370 380 390 400 410 CCDS44 RVTEHLPPAEPDH 420 393 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 17:12:14 2016 done: Tue Nov 8 17:12:14 2016 Total Scan time: 1.770 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]