FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2626, 302 aa 1>>>pF1KE2626 302 - 302 aa - 302 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3111+/-0.00037; mu= 11.1290+/- 0.023 mean_var=104.9316+/-20.784, 0's: 0 Z-trim(116.2): 47 B-trim: 291 in 2/51 Lambda= 0.125205 statistics sampled from 28303 (28347) to 28303 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.307), width: 16 Scan time: 3.940 The best scores are: opt bits E(92320) NP_060389 (OMIM: 604204) syntaxin-17 [Homo sapiens ( 302) 1924 358.0 1.4e-98 XP_011517123 (OMIM: 604204) syntaxin-17 isoform X1 ( 302) 1924 358.0 1.4e-98 XP_011517122 (OMIM: 604204) syntaxin-17 isoform X1 ( 302) 1924 358.0 1.4e-98 XP_016870364 (OMIM: 604204) syntaxin-17 isoform X2 ( 213) 1343 253.0 4.2e-67 XP_011517125 (OMIM: 604204) syntaxin-17 isoform X2 ( 213) 1343 253.0 4.2e-67 XP_024303361 (OMIM: 604204) syntaxin-17 isoform X2 ( 213) 1343 253.0 4.2e-67 >>NP_060389 (OMIM: 604204) syntaxin-17 [Homo sapiens] (302 aa) initn: 1924 init1: 1924 opt: 1924 Z-score: 1891.4 bits: 358.0 E(92320): 1.4e-98 Smith-Waterman score: 1924; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE2 MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 TVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 NDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 NDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 ELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 GMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 GMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKK 250 260 270 280 290 300 pF1KE2 CS :: NP_060 CS >>XP_011517123 (OMIM: 604204) syntaxin-17 isoform X1 [Ho (302 aa) initn: 1924 init1: 1924 opt: 1924 Z-score: 1891.4 bits: 358.0 E(92320): 1.4e-98 Smith-Waterman score: 1924; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE2 MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 NDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 ELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 GMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKK 250 260 270 280 290 300 pF1KE2 CS :: XP_011 CS >>XP_011517122 (OMIM: 604204) syntaxin-17 isoform X1 [Ho (302 aa) initn: 1924 init1: 1924 opt: 1924 Z-score: 1891.4 bits: 358.0 E(92320): 1.4e-98 Smith-Waterman score: 1924; 100.0% identity (100.0% similar) in 302 aa overlap (1-302:1-302) 10 20 30 40 50 60 pF1KE2 MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSEDEEKVKLRRLEPAIQKFIKIVIPTDLERLRKHQINIEKYQRCRIWDKLHEEHINAGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 TVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 NDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADLI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 ELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALIG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 GMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDKK 250 260 270 280 290 300 pF1KE2 CS :: XP_011 CS >>XP_016870364 (OMIM: 604204) syntaxin-17 isoform X2 [Ho (213 aa) initn: 1343 init1: 1343 opt: 1343 Z-score: 1326.4 bits: 253.0 E(92320): 4.2e-67 Smith-Waterman score: 1343; 100.0% identity (100.0% similar) in 213 aa overlap (90-302:1-213) 60 70 80 90 100 110 pF1KE2 RTVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQ :::::::::::::::::::::::::::::: XP_016 MIDPVKEEASAATAEFLQLHLESVEELKKQ 10 20 30 120 130 140 150 160 170 pF1KE2 FNDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADL 40 50 60 70 80 90 180 190 200 210 220 230 pF1KE2 IELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALI 100 110 120 130 140 150 240 250 260 270 280 290 pF1KE2 GGMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDK 160 170 180 190 200 210 300 pF1KE2 KCS ::: XP_016 KCS >>XP_011517125 (OMIM: 604204) syntaxin-17 isoform X2 [Ho (213 aa) initn: 1343 init1: 1343 opt: 1343 Z-score: 1326.4 bits: 253.0 E(92320): 4.2e-67 Smith-Waterman score: 1343; 100.0% identity (100.0% similar) in 213 aa overlap (90-302:1-213) 60 70 80 90 100 110 pF1KE2 RTVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQ :::::::::::::::::::::::::::::: XP_011 MIDPVKEEASAATAEFLQLHLESVEELKKQ 10 20 30 120 130 140 150 160 170 pF1KE2 FNDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADL 40 50 60 70 80 90 180 190 200 210 220 230 pF1KE2 IELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALI 100 110 120 130 140 150 240 250 260 270 280 290 pF1KE2 GGMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDK 160 170 180 190 200 210 300 pF1KE2 KCS ::: XP_011 KCS >>XP_024303361 (OMIM: 604204) syntaxin-17 isoform X2 [Ho (213 aa) initn: 1343 init1: 1343 opt: 1343 Z-score: 1326.4 bits: 253.0 E(92320): 4.2e-67 Smith-Waterman score: 1343; 100.0% identity (100.0% similar) in 213 aa overlap (90-302:1-213) 60 70 80 90 100 110 pF1KE2 RTVQQLRSNIREIEKLCLKVRKDDLVLLKRMIDPVKEEASAATAEFLQLHLESVEELKKQ :::::::::::::::::::::::::::::: XP_024 MIDPVKEEASAATAEFLQLHLESVEELKKQ 10 20 30 120 130 140 150 160 170 pF1KE2 FNDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 FNDEETLLQPPLTRSMTVGGAFHTTEAEASSQSLTQIYALPEIPQDQNAAESWETLEADL 40 50 60 70 80 90 180 190 200 210 220 230 pF1KE2 IELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 IELSQLVTDFSLLVNSQQEKIDSIADHVNSAAVNVEEGTKNLGKAAKYKLAALPVAGALI 100 110 120 130 140 150 240 250 260 270 280 290 pF1KE2 GGMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_024 GGMVGGPIGLLAGFKVAGIAAALGGGVLGFTGGKLIQRKKQKMMEKLTSSCPDLPSQTDK 160 170 180 190 200 210 300 pF1KE2 KCS ::: XP_024 KCS 302 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:43:27 2019 done: Thu Oct 24 21:43:28 2019 Total Scan time: 3.940 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]