FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2636, 354 aa
1>>>pF1KE2636 354 - 354 aa - 354 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4052+/-0.000809; mu= 15.5019+/- 0.049
mean_var=67.2252+/-13.593, 0's: 0 Z-trim(106.8): 47 B-trim: 0 in 0/51
Lambda= 0.156426
statistics sampled from 9164 (9206) to 9164 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.283), width: 16
Scan time: 2.450
The best scores are: opt bits E(32554)
CCDS47242.1 VCAN gene_id:1462|Hs108|chr5 ( 655) 2384 547.1 1.6e-155
CCDS54876.1 VCAN gene_id:1462|Hs108|chr5 (2409) 2385 547.6 4e-155
CCDS54875.1 VCAN gene_id:1462|Hs108|chr5 (1642) 2378 545.9 8.6e-155
CCDS4060.1 VCAN gene_id:1462|Hs108|chr5 (3396) 2378 546.1 1.6e-154
CCDS53971.1 ACAN gene_id:176|Hs108|chr15 (2431) 1208 282.0 3.7e-75
CCDS53970.1 ACAN gene_id:176|Hs108|chr15 (2530) 1208 282.0 3.8e-75
CCDS12397.1 NCAN gene_id:1463|Hs108|chr19 (1321) 1127 263.6 7e-70
CCDS1150.1 BCAN gene_id:63827|Hs108|chr1 ( 671) 1092 255.5 9.4e-68
CCDS1149.1 BCAN gene_id:63827|Hs108|chr1 ( 911) 1092 255.6 1.2e-67
CCDS4061.1 HAPLN1 gene_id:1404|Hs108|chr5 ( 354) 780 185.0 8.6e-47
CCDS10346.1 HAPLN3 gene_id:145864|Hs108|chr15 ( 360) 753 178.9 5.9e-45
CCDS76790.1 HAPLN3 gene_id:145864|Hs108|chr15 ( 422) 753 178.9 6.8e-45
CCDS1148.1 HAPLN2 gene_id:60484|Hs108|chr1 ( 340) 681 162.6 4.4e-40
CCDS12398.1 HAPLN4 gene_id:404037|Hs108|chr19 ( 402) 382 95.2 1e-19
>>CCDS47242.1 VCAN gene_id:1462|Hs108|chr5 (655 aa)
initn: 2382 init1: 2382 opt: 2384 Z-score: 2905.8 bits: 547.1 E(32554): 1.6e-155
Smith-Waterman score: 2384; 99.1% identity (99.4% similar) in 352 aa overlap (1-350:1-352)
10 20 30 40 50 60
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKR--KCLIPF
:::::::::::::::::::::::::::::::::::::::::::::::: .:
CCDS47 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRPDRCKMNPCLNG
310 320 330 340 350 360
CCDS47 GTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGAL
370 380 390 400 410 420
>>CCDS54876.1 VCAN gene_id:1462|Hs108|chr5 (2409 aa)
initn: 2565 init1: 2385 opt: 2385 Z-score: 2898.5 bits: 547.6 E(32554): 4e-155
Smith-Waterman score: 2385; 99.7% identity (100.0% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF
::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS54 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRRMSDLSVIGHPI
310 320 330 340 350 360
CCDS54 DSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPS
370 380 390 400 410 420
>>CCDS54875.1 VCAN gene_id:1462|Hs108|chr5 (1642 aa)
initn: 2558 init1: 2378 opt: 2378 Z-score: 2892.5 bits: 545.9 E(32554): 8.6e-155
Smith-Waterman score: 2378; 99.7% identity (99.7% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF
::::::::::::::::::::::::::::::::::::::::::::::: :
CCDS54 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILA
310 320 330 340 350 360
CCDS54 ETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAITDSLA
370 380 390 400 410 420
>>CCDS4060.1 VCAN gene_id:1462|Hs108|chr5 (3396 aa)
initn: 2558 init1: 2378 opt: 2378 Z-score: 2887.7 bits: 546.1 E(32554): 1.6e-154
Smith-Waterman score: 2378; 99.7% identity (99.7% similar) in 349 aa overlap (1-349:1-349)
10 20 30 40 50 60
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS40 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF
::::::::::::::::::::::::::::::::::::::::::::::: :
CCDS40 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILA
310 320 330 340 350 360
CCDS40 ETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAITDSLA
370 380 390 400 410 420
>>CCDS53971.1 ACAN gene_id:176|Hs108|chr15 (2431 aa)
initn: 2211 init1: 1140 opt: 1208 Z-score: 1462.9 bits: 282.0 E(32554): 3.7e-75
Smith-Waterman score: 1208; 49.9% identity (77.5% similar) in 355 aa overlap (5-346:1-349)
10 20 30 40
pF1KE2 MFINIKSILWMCSTL-IVTHAL------H----KVKVGKSPPVRGSLSGKVSLPCHF-ST
. ..::. :: ..: :. : .:.. . :.: :. ....::.: .
CCDS53 MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDP
10 20 30 40 50
50 60 70 80 90 100
pF1KE2 MPTLPPSYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHP
: . . .:. . :::::.. . ::...::: .: ..... :. .::.:..:
CCDS53 MHPVTTAPSTAPLAPRIKWSRVSKE------KEVVLLVATEGRVRVNSAYQDKVSLPNYP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 EAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEA
.::.: : .: ..:.:.:::.::.::::.. :. ..: :.:::::: ..::::.:.
CCDS53 AIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDR
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 AQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGV
::.:::. .:.::::::: :::::::.::::::::::::::::..:: :::::: ::
CCDS53 AQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 RTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
::::.:. .:::::::......:.::. : : ::::.:::.::. :::::.:.: ::
CCDS53 RTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAW
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 RNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK
. :.:.:. :::.: :::.:.. :: .:::.::::::.: ::::.: :.::.:: :.
CCDS53 QAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT
300 310 320 330 340 350
350
pF1KE2 RKCLIPF
CCDS53 GEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPS
360 370 380 390 400 410
>--
initn: 1077 init1: 858 opt: 863 Z-score: 1042.1 bits: 204.1 E(32554): 1e-51
Smith-Waterman score: 863; 59.0% identity (78.0% similar) in 205 aa overlap (149-353:477-681)
120 130 140 150 160 170
pF1KE2 KLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAV
::::::: . .::.:.:: ::.::: .:::
CCDS53 TPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAV
450 460 470 480 490 500
180 190 200 210 220 230
pF1KE2 IATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQET
::.:::: :::: :.:::::::: :::::::: .::. : ::: .. :::::: : ::
CCDS53 IASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
510 520 530 540 550 560
240 250 260 270 280 290
pF1KE2 YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGW
:::::.::.:.:.:: : .:::.:: . ::...: :::.:.: ::: :.:.: ::
CCDS53 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGW
570 580 590 600 610 620
300 310 320 330 340 350
pF1KE2 LSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF
:.:.:.:.:... : ::: ::::.: . ::::.: : :: :.::. .:
CCDS53 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEE
630 640 650 660 670 680
CCDS53 EGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAY
690 700 710 720 730 740
>>CCDS53970.1 ACAN gene_id:176|Hs108|chr15 (2530 aa)
initn: 2211 init1: 1140 opt: 1208 Z-score: 1462.6 bits: 282.0 E(32554): 3.8e-75
Smith-Waterman score: 1208; 49.9% identity (77.5% similar) in 355 aa overlap (5-346:1-349)
10 20 30 40
pF1KE2 MFINIKSILWMCSTL-IVTHAL------H----KVKVGKSPPVRGSLSGKVSLPCHF-ST
. ..::. :: ..: :. : .:.. . :.: :. ....::.: .
CCDS53 MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDP
10 20 30 40 50
50 60 70 80 90 100
pF1KE2 MPTLPPSYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHP
: . . .:. . :::::.. . ::...::: .: ..... :. .::.:..:
CCDS53 MHPVTTAPSTAPLAPRIKWSRVSKE------KEVVLLVATEGRVRVNSAYQDKVSLPNYP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE2 EAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEA
.::.: : .: ..:.:.:::.::.::::.. :. ..: :.:::::: ..::::.:.
CCDS53 AIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDR
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 AQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGV
::.:::. .:.::::::: :::::::.::::::::::::::::..:: :::::: ::
CCDS53 AQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 RTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
::::.:. .:::::::......:.::. : : ::::.:::.::. :::::.:.: ::
CCDS53 RTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAW
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 RNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK
. :.:.:. :::.: :::.:.. :: .:::.::::::.: ::::.: :.::.:: :.
CCDS53 QAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT
300 310 320 330 340 350
350
pF1KE2 RKCLIPF
CCDS53 GEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPS
360 370 380 390 400 410
>--
initn: 1077 init1: 858 opt: 863 Z-score: 1041.8 bits: 204.1 E(32554): 1e-51
Smith-Waterman score: 863; 59.0% identity (78.0% similar) in 205 aa overlap (149-353:477-681)
120 130 140 150 160 170
pF1KE2 KLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAV
::::::: . .::.:.:: ::.::: .:::
CCDS53 TPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAV
450 460 470 480 490 500
180 190 200 210 220 230
pF1KE2 IATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQET
::.:::: :::: :.:::::::: :::::::: .::. : ::: .. :::::: : ::
CCDS53 IASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
510 520 530 540 550 560
240 250 260 270 280 290
pF1KE2 YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGW
:::::.::.:.:.:: : .:::.:: . ::...: :::.:.: ::: :.:.: ::
CCDS53 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGW
570 580 590 600 610 620
300 310 320 330 340 350
pF1KE2 LSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF
:.:.:.:.:... : ::: ::::.: . ::::.: : :: :.::. .:
CCDS53 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEE
630 640 650 660 670 680
CCDS53 EGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAY
690 700 710 720 730 740
>>CCDS12397.1 NCAN gene_id:1463|Hs108|chr19 (1321 aa)
initn: 1219 init1: 1038 opt: 1127 Z-score: 1368.1 bits: 263.6 E(32554): 7e-70
Smith-Waterman score: 1127; 49.8% identity (76.5% similar) in 327 aa overlap (21-347:37-357)
10 20 30 40 50
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMP
:: :.: : :...:. :.::: :. .:
CCDS12 WALGLLMLQMLLFVAGEQGTQDITDASERGLHMQKLG-SGSVQAALAELVALPCLFTLQP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 TLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAV
:: . . ::::.:... .. . .. .:::... ........::::.:..:.
CCDS12 R--PS-AARDAPRIKWTKVRTASGQR--QDLPILVAKDNVVRVAKSWQGRVSLPSYPRRR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 GDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQK
..:.: . : :::.:::::.:. :::: :: : : : :::::::.: .::.:.: ::.
CCDS12 ANATLLLGPLRASDSGLYRCQVVRGIEDEQDLVPLEVTGVVFHYRSARDRYALTFAEAQE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE2 ACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTY
:: .:.::.:..: ::.::::..::::::.:.:::::: : :::::. . :::.:
CCDS12 ACRLSSAIIAAPRHLQAAFEDGFDNCDAGWLSDRTVRYPITQSRPGCYGDRSSLPGVRSY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE2 GFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNG
: :.::: :::::.. .: :.::.. ..:. : .:. : : ::.::.:. ::..:
CCDS12 GRRNPQELYDVYCFARELGGEVFYVGPARRLTLAGARAQCRRQGAALASVGQLHLAWHEG
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE2 FDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKC
.:::: :::.:.:::.:. . : .::: ::::.::: :.:::: : :::::::.
CCDS12 LDQCDPGWLADGSVRYPIQTPRRRCGGPAPGVRTVYRFANRTGFPSPAERFDAYCFRAHH
310 320 330 340 350 360
pF1KE2 LIPF
CCDS12 PTSQHGDLETPSSGDEGEILSAEGPPVRELEPTLEEEEVVTPDFQEPLVSSGEEETLILE
370 380 390 400 410 420
>>CCDS1150.1 BCAN gene_id:63827|Hs108|chr1 (671 aa)
initn: 1230 init1: 1013 opt: 1092 Z-score: 1329.9 bits: 255.5 E(32554): 9.4e-68
Smith-Waterman score: 1092; 46.8% identity (76.3% similar) in 325 aa overlap (23-347:36-354)
10 20 30 40 50
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTL
.:... . :..: :.: ...::: .
CCDS11 LPLLAALVLAQAPAALADVLEGDSSEDRAFRVRIAGDAPLQGVLGGALTIPCHVHYLRPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 PPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGD
: . :.::. . . :. :. ::::.. .:... :. ::..:..: .. :
CCDS11 PSRRAVLGSPRVKWTFL---SRGR---EAEVLVARGVRVKVNEAYRFRVALPAYPASLTD
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 ASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKAC
.::.. .: .:.:.:::.:..::.:..:.: . : :::: :: ...::...: .::.::
CCDS11 VSLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEAC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 LDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGF
.:: :::::::.::: :.::::::::.::::::::..:: .:::: : :::.::
CCDS11 ARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 RSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFD
.:.. ::::::.. :.:..: : :.:.::: :... :..::.:.: ::: .:.:
CCDS11 VDPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 QCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLI
.:. :::.:.:::.:... .::::: ::.::. : :::::: :::..:::.
CCDS11 HCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQP
300 310 320 330 340 350
pF1KE2 PF
CCDS11 SAIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAIYSIPIMEDGGGGSS
360 370 380 390 400 410
>>CCDS1149.1 BCAN gene_id:63827|Hs108|chr1 (911 aa)
initn: 1230 init1: 1013 opt: 1092 Z-score: 1327.9 bits: 255.6 E(32554): 1.2e-67
Smith-Waterman score: 1092; 46.8% identity (76.3% similar) in 325 aa overlap (23-347:36-354)
10 20 30 40 50
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTL
.:... . :..: :.: ...::: .
CCDS11 LPLLAALVLAQAPAALADVLEGDSSEDRAFRVRIAGDAPLQGVLGGALTIPCHVHYLRPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 PPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGD
: . :.::. . . :. :. ::::.. .:... :. ::..:..: .. :
CCDS11 PSRRAVLGSPRVKWTFL---SRGR---EAEVLVARGVRVKVNEAYRFRVALPAYPASLTD
70 80 90 100 110
120 130 140 150 160 170
pF1KE2 ASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKAC
.::.. .: .:.:.:::.:..::.:..:.: . : :::: :: ...::...: .::.::
CCDS11 VSLALSELRPNDSGIYRCEVQHGIDDSSDAVEVKVKGVVFLYREGSARYAFSFSGAQEAC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 LDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGF
.:: :::::::.::: :.::::::::.::::::::..:: .:::: : :::.::
CCDS11 ARIGAHIATPEQLYAAYLGGYEQCDAGWLSDQTVRYPIQTPREACYGDMDGFPGVRNYGV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 RSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFD
.:.. ::::::.. :.:..: : :.:.::: :... :..::.:.: ::: .:.:
CCDS11 VDPDDLYDVYCYAEDLNGELFLGDPPEKLTLEEARAYCQERGAEIATTGQLYAAWDGGLD
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE2 QCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLI
.:. :::.:.:::.:... .::::: ::.::. : :::::: :::..:::.
CCDS11 HCSPGWLADGSVRYPIVTPSQRCGGGLPGVKTLFLFPNQTGFPNKHSRFNVYCFRDSAQP
300 310 320 330 340 350
pF1KE2 PF
CCDS11 SAIPEASNPASNPASDGLEAIVTVTETLEELQLPQEATESESRGAIYSIPIMEDGGGGSS
360 370 380 390 400 410
>>CCDS4061.1 HAPLN1 gene_id:1404|Hs108|chr5 (354 aa)
initn: 700 init1: 505 opt: 780 Z-score: 953.6 bits: 185.0 E(32554): 8.6e-47
Smith-Waterman score: 782; 39.5% identity (66.3% similar) in 332 aa overlap (19-347:39-351)
10 20 30 40
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFST
: : ... .: :: :.:.:::.:
CCDS40 LISICWADHLSDNYTLDHDRAIHIQAENGPHLLVEAEQAKVFSHRG---GNVTLPCKFYR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 MPTLPPSYNTSEFLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPE
:: : . .::::.:. : :::. :.:... . : :.::: . .
CCDS40 DPTAFGSGIHK--IRIKWTKLTSDY----LKEVDVFVSMGYHKKTYGGYQGRVFLKGGSD
70 80 90 100 110
110 120 130 140 150 160
pF1KE2 AVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAA
. ::::... : : : :.:.:. :.:: .:.: ..:::: : .::.:::. :
CCDS40 S--DASLVITDLTLEDYGRYKCEVIEGLEDDTVVVALDLQGVVFPYFPRLGRYNLNFHEA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 QKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVR
:.:::: ::::. .::. :.. :.. :.::::.: .:.::: :: : : . :::
CCDS40 QQACLDQDAVIASFDQLYDAWRGGLDWCNAGWLSDGSVQYPITKPREPC-GGQNTVPGVR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 TYGFRSPQET-YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
.::: . ... :::.:......: ..: :.:.:..::.. : :. :..: ::.. :::
CCDS40 NYGFWDKDKSRYDVFCFTSNFNGRFYYLIHPTKLTYDEAVQACLNDGAQIAKVGQIFAAW
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE2 RN-GFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSR-FDAYC
. :.:.:: :::.:.:::.:.. : .:. .:: . ::: . . .::
CCDS40 KILGYDRCDAGWLADGSVRYPISRPRRRCSPTEAAVRFV-------GFPDKKHKLYGVYC
300 310 320 330 340
350
pF1KE2 FKRKCLIPF
:.
CCDS40 FRAYN
350
354 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:35:30 2016 done: Tue Nov 8 17:35:31 2016
Total Scan time: 2.450 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]