Result of FASTA (omim) for pF1KE2636
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2636, 354 aa
  1>>>pF1KE2636 354 - 354 aa - 354 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4419+/-0.00035; mu= 15.4809+/- 0.022
 mean_var=71.5367+/-14.392, 0's: 0 Z-trim(113.9): 86  B-trim: 0 in 0/56
 Lambda= 0.151639
 statistics sampled from 23406 (23503) to 23406 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.276), width:  16
 Scan time:  6.400

The best scores are:                                      opt bits E(85289)
NP_001119808 (OMIM: 118661,143200) versican core p ( 655) 2384 531.0 2.9e-150
NP_001157569 (OMIM: 118661,143200) versican core p (2409) 2385 531.5 7.3e-150
NP_001157570 (OMIM: 118661,143200) versican core p (1642) 2378 529.9 1.5e-149
NP_004376 (OMIM: 118661,143200) versican core prot (3396) 2378 530.1 2.8e-149
NP_001126 (OMIM: 155760,165800,608361,612813) aggr (2431) 1208 274.0 2.4e-72
XP_011519616 (OMIM: 155760,165800,608361,612813) P (2492) 1208 274.0 2.4e-72
XP_016877476 (OMIM: 155760,165800,608361,612813) P (2515) 1208 274.0 2.5e-72
NP_037359 (OMIM: 155760,165800,608361,612813) aggr (2530) 1208 274.0 2.5e-72
XP_011519615 (OMIM: 155760,165800,608361,612813) P (2530) 1208 274.0 2.5e-72
XP_016877474 (OMIM: 155760,165800,608361,612813) P (2553) 1208 274.0 2.5e-72
XP_016877475 (OMIM: 155760,165800,608361,612813) P (2553) 1208 274.0 2.5e-72
XP_006720482 (OMIM: 155760,165800,608361,612813) P (2568) 1208 274.0 2.5e-72
NP_004377 (OMIM: 600826) neurocan core protein pre (1321) 1127 256.1 3.1e-67
NP_940819 (OMIM: 600347) brevican core protein iso ( 671) 1092 248.3 3.6e-65
XP_011508168 (OMIM: 600347) PREDICTED: brevican co ( 911) 1092 248.4 4.7e-65
NP_068767 (OMIM: 600347) brevican core protein iso ( 911) 1092 248.4 4.7e-65
XP_016857536 (OMIM: 600347) PREDICTED: brevican co ( 956) 1092 248.4 4.8e-65
XP_016864543 (OMIM: 115435) PREDICTED: hyaluronan  ( 353)  780 179.9 7.5e-45
XP_016864542 (OMIM: 115435) PREDICTED: hyaluronan  ( 353)  780 179.9 7.5e-45
XP_016864540 (OMIM: 115435) PREDICTED: hyaluronan  ( 354)  780 179.9 7.5e-45
XP_016864541 (OMIM: 115435) PREDICTED: hyaluronan  ( 354)  780 179.9 7.5e-45
XP_011541470 (OMIM: 115435) PREDICTED: hyaluronan  ( 354)  780 179.9 7.5e-45
NP_001875 (OMIM: 115435) hyaluronan and proteoglyc ( 354)  780 179.9 7.5e-45
XP_016861492 (OMIM: 608560) PREDICTED: stabilin-1  (2555)  245 63.4 6.6e-09
XP_016861491 (OMIM: 608560) PREDICTED: stabilin-1  (2565)  245 63.4 6.6e-09
XP_005265031 (OMIM: 608560) PREDICTED: stabilin-1  (2569)  245 63.4 6.6e-09
NP_055951 (OMIM: 608560) stabilin-1 precursor [Hom (2570)  245 63.4 6.6e-09
XP_016861490 (OMIM: 608560) PREDICTED: stabilin-1  (2583)  245 63.4 6.6e-09
XP_016861489 (OMIM: 608560) PREDICTED: stabilin-1  (2589)  245 63.4 6.6e-09
XP_016861488 (OMIM: 608560) PREDICTED: stabilin-1  (2590)  245 63.4 6.6e-09
XP_005265030 (OMIM: 608560) PREDICTED: stabilin-1  (2595)  245 63.4 6.6e-09
XP_016861487 (OMIM: 608560) PREDICTED: stabilin-1  (2615)  245 63.4 6.7e-09
XP_011536844 (OMIM: 608561) PREDICTED: stabilin-2  (1238)  197 52.7 5.2e-06
XP_011536843 (OMIM: 608561) PREDICTED: stabilin-2  (1684)  197 52.7 6.7e-06
XP_011536841 (OMIM: 608561) PREDICTED: stabilin-2  (1994)  197 52.8 7.7e-06
NP_060034 (OMIM: 608561) stabilin-2 precursor [Hom (2551)  197 52.8 9.5e-06
NP_009046 (OMIM: 600410) tumor necrosis factor-ind ( 277)  170 46.4 9.1e-05
NP_001193993 (OMIM: 602621) coxsackievirus and ade ( 200)  143 40.4  0.0042
NP_005805 (OMIM: 602171) cell surface A33 antigen  ( 319)  142 40.3  0.0072


>>NP_001119808 (OMIM: 118661,143200) versican core prote  (655 aa)
 initn: 2382 init1: 2382 opt: 2384  Z-score: 2818.7  bits: 531.0 E(85289): 2.9e-150
Smith-Waterman score: 2384; 99.1% identity (99.4% similar) in 352 aa overlap (1-350:1-352)

               10        20        30        40        50        60
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
              250       260       270       280       290       300

              310       320       330       340         350        
pF1KE2 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKR--KCLIPF    
       ::::::::::::::::::::::::::::::::::::::::::::::::  .:        
NP_001 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRPDRCKMNPCLNG
              310       320       330       340       350       360

NP_001 GTCYPTETSYVCTCVPGYSGDQCELDFDECHSNPCRNGATCVDGFNTFRCLCLPSYVGAL
              370       380       390       400       410       420

>>NP_001157569 (OMIM: 118661,143200) versican core prote  (2409 aa)
 initn: 2565 init1: 2385 opt: 2385  Z-score: 2811.5  bits: 531.5 E(85289): 7.3e-150
Smith-Waterman score: 2385; 99.7% identity (100.0% similar) in 349 aa overlap (1-349:1-349)

               10        20        30        40        50        60
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
              250       260       270       280       290       300

              310       320       330       340       350          
pF1KE2 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF      
       ::::::::::::::::::::::::::::::::::::::::::::::::.           
NP_001 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRRMSDLSVIGHPI
              310       320       330       340       350       360

NP_001 DSESKEDEPCSEETDPVHDLMAEILPEFPDIIEIDLYHSEENEEEEEECANATDVTTTPS
              370       380       390       400       410       420

>>NP_001157570 (OMIM: 118661,143200) versican core prote  (1642 aa)
 initn: 2558 init1: 2378 opt: 2378  Z-score: 2805.7  bits: 529.9 E(85289): 1.5e-149
Smith-Waterman score: 2378; 99.7% identity (99.7% similar) in 349 aa overlap (1-349:1-349)

               10        20        30        40        50        60
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
              250       260       270       280       290       300

              310       320       330       340       350          
pF1KE2 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF      
       ::::::::::::::::::::::::::::::::::::::::::::::: :           
NP_001 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILA
              310       320       330       340       350       360

NP_001 ETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAITDSLA
              370       380       390       400       410       420

>>NP_004376 (OMIM: 118661,143200) versican core protein   (3396 aa)
 initn: 2558 init1: 2378 opt: 2378  Z-score: 2801.0  bits: 530.1 E(85289): 2.8e-149
Smith-Waterman score: 2378; 99.7% identity (99.7% similar) in 349 aa overlap (1-349:1-349)

               10        20        30        40        50        60
pF1KE2 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MFINIKSILWMCSTLIVTHALHKVKVGKSPPVRGSLSGKVSLPCHFSTMPTLPPSYNTSE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FLRIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHPEAVGDASLTVVKL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAVIA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQETYD
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGWLS
              250       260       270       280       290       300

              310       320       330       340       350          
pF1KE2 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF      
       ::::::::::::::::::::::::::::::::::::::::::::::: :           
NP_004 DASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKPKEATTIDLSILA
              310       320       330       340       350       360

NP_004 ETASPSLSKEPQMVSDRTTPIIPLVDELPVIPTEFPPVGNIVSFEQKATVQPQAITDSLA
              370       380       390       400       410       420

>>NP_001126 (OMIM: 155760,165800,608361,612813) aggrecan  (2431 aa)
 initn: 2211 init1: 1140 opt: 1208  Z-score: 1419.8  bits: 274.0 E(85289): 2.4e-72
Smith-Waterman score: 1208; 49.9% identity (77.5% similar) in 355 aa overlap (5-346:1-349)

               10         20                  30        40         
pF1KE2 MFINIKSILWMCSTL-IVTHAL------H----KVKVGKSPPVRGSLSGKVSLPCHF-ST
           . ..::.  :: ..: :.      :    .:.. .  :.:  :. ....::.: . 
NP_001     MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDP
                   10        20        30        40        50      

       50        60         70        80        90       100       
pF1KE2 MPTLPPSYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHP
       :  .  . .:. .  :::::..  .      ::...::: .: ..... :. .::.:..:
NP_001 MHPVTTAPSTAPLAPRIKWSRVSKE------KEVVLLVATEGRVRVNSAYQDKVSLPNYP
         60        70        80              90       100       110

       110       120       130       140       150       160       
pF1KE2 EAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEA
          .::.: : .: ..:.:.:::.::.::::.. :. ..: :.:::::: ..::::.:. 
NP_001 AIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDR
              120       130       140       150       160       170

       170       180       190       200       210       220       
pF1KE2 AQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGV
       ::.:::. .:.::::::: :::::::.::::::::::::::::..:: ::::::    ::
NP_001 AQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGV
              180       190       200       210       220       230

       230       240       250       260       270       280       
pF1KE2 RTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
       ::::.:. .:::::::......:.::. : : ::::.:::.::.   :::::.:.:  ::
NP_001 RTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAW
              240       250       260       270       280       290

       290       300       310       320       330       340       
pF1KE2 RNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK
       . :.:.:. :::.: :::.:.. :: .:::.::::::.:   ::::.: :.::.:: :. 
NP_001 QAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT
              300       310       320       330       340       350

       350                                                         
pF1KE2 RKCLIPF                                                     
                                                                   
NP_001 GEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPS
              360       370       380       390       400       410

>--
 initn: 1077 init1: 858 opt: 863  Z-score: 1011.9  bits: 198.5 E(85289): 1.3e-49
Smith-Waterman score: 863; 59.0% identity (78.0% similar) in 205 aa overlap (149-353:477-681)

      120       130       140       150       160       170        
pF1KE2 KLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAV
                                     ::::::: . .::.:.:: ::.::: .:::
NP_001 TPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAV
        450       460       470       480       490       500      

      180       190       200       210       220       230        
pF1KE2 IATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQET
       ::.:::: :::: :.:::::::: :::::::: .::. : ::: .. :::::: :   ::
NP_001 IASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
        510       520       530       540       550       560      

      240       250       260       270       280       290        
pF1KE2 YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGW
       :::::.::.:.:.::  :   .:::.:: . ::...: :::.:.: :::  :.:.:  ::
NP_001 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGW
        570       580       590       600       610       620      

      300       310       320       330       340       350        
pF1KE2 LSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF    
       :.:.:.:.:... :  :::   ::::.: . ::::.: : ::  :.::.    .:     
NP_001 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEE
        630       640       650       660       670       680      

NP_001 EGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAY
        690       700       710       720       730       740      

>>XP_011519616 (OMIM: 155760,165800,608361,612813) PREDI  (2492 aa)
 initn: 2211 init1: 1140 opt: 1208  Z-score: 1419.7  bits: 274.0 E(85289): 2.4e-72
Smith-Waterman score: 1208; 49.9% identity (77.5% similar) in 355 aa overlap (5-346:1-349)

               10         20                  30        40         
pF1KE2 MFINIKSILWMCSTL-IVTHAL------H----KVKVGKSPPVRGSLSGKVSLPCHF-ST
           . ..::.  :: ..: :.      :    .:.. .  :.:  :. ....::.: . 
XP_011     MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDP
                   10        20        30        40        50      

       50        60         70        80        90       100       
pF1KE2 MPTLPPSYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHP
       :  .  . .:. .  :::::..  .      ::...::: .: ..... :. .::.:..:
XP_011 MHPVTTAPSTAPLAPRIKWSRVSKE------KEVVLLVATEGRVRVNSAYQDKVSLPNYP
         60        70        80              90       100       110

       110       120       130       140       150       160       
pF1KE2 EAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEA
          .::.: : .: ..:.:.:::.::.::::.. :. ..: :.:::::: ..::::.:. 
XP_011 AIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDR
              120       130       140       150       160       170

       170       180       190       200       210       220       
pF1KE2 AQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGV
       ::.:::. .:.::::::: :::::::.::::::::::::::::..:: ::::::    ::
XP_011 AQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGV
              180       190       200       210       220       230

       230       240       250       260       270       280       
pF1KE2 RTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
       ::::.:. .:::::::......:.::. : : ::::.:::.::.   :::::.:.:  ::
XP_011 RTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAW
              240       250       260       270       280       290

       290       300       310       320       330       340       
pF1KE2 RNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK
       . :.:.:. :::.: :::.:.. :: .:::.::::::.:   ::::.: :.::.:: :. 
XP_011 QAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT
              300       310       320       330       340       350

       350                                                         
pF1KE2 RKCLIPF                                                     
                                                                   
XP_011 GEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPS
              360       370       380       390       400       410

>--
 initn: 1077 init1: 858 opt: 863  Z-score: 1011.8  bits: 198.5 E(85289): 1.3e-49
Smith-Waterman score: 863; 59.0% identity (78.0% similar) in 205 aa overlap (149-353:477-681)

      120       130       140       150       160       170        
pF1KE2 KLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAV
                                     ::::::: . .::.:.:: ::.::: .:::
XP_011 TPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAV
        450       460       470       480       490       500      

      180       190       200       210       220       230        
pF1KE2 IATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQET
       ::.:::: :::: :.:::::::: :::::::: .::. : ::: .. :::::: :   ::
XP_011 IASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
        510       520       530       540       550       560      

      240       250       260       270       280       290        
pF1KE2 YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGW
       :::::.::.:.:.::  :   .:::.:: . ::...: :::.:.: :::  :.:.:  ::
XP_011 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGW
        570       580       590       600       610       620      

      300       310       320       330       340       350        
pF1KE2 LSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF    
       :.:.:.:.:... :  :::   ::::.: . ::::.: : ::  :.::.    .:     
XP_011 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEE
        630       640       650       660       670       680      

XP_011 EGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAY
        690       700       710       720       730       740      

>>XP_016877476 (OMIM: 155760,165800,608361,612813) PREDI  (2515 aa)
 initn: 2211 init1: 1140 opt: 1208  Z-score: 1419.6  bits: 274.0 E(85289): 2.5e-72
Smith-Waterman score: 1208; 49.9% identity (77.5% similar) in 355 aa overlap (5-346:1-349)

               10         20                  30        40         
pF1KE2 MFINIKSILWMCSTL-IVTHAL------H----KVKVGKSPPVRGSLSGKVSLPCHF-ST
           . ..::.  :: ..: :.      :    .:.. .  :.:  :. ....::.: . 
XP_016     MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDP
                   10        20        30        40        50      

       50        60         70        80        90       100       
pF1KE2 MPTLPPSYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHP
       :  .  . .:. .  :::::..  .      ::...::: .: ..... :. .::.:..:
XP_016 MHPVTTAPSTAPLAPRIKWSRVSKE------KEVVLLVATEGRVRVNSAYQDKVSLPNYP
         60        70        80              90       100       110

       110       120       130       140       150       160       
pF1KE2 EAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEA
          .::.: : .: ..:.:.:::.::.::::.. :. ..: :.:::::: ..::::.:. 
XP_016 AIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDR
              120       130       140       150       160       170

       170       180       190       200       210       220       
pF1KE2 AQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGV
       ::.:::. .:.::::::: :::::::.::::::::::::::::..:: ::::::    ::
XP_016 AQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGV
              180       190       200       210       220       230

       230       240       250       260       270       280       
pF1KE2 RTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
       ::::.:. .:::::::......:.::. : : ::::.:::.::.   :::::.:.:  ::
XP_016 RTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAW
              240       250       260       270       280       290

       290       300       310       320       330       340       
pF1KE2 RNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK
       . :.:.:. :::.: :::.:.. :: .:::.::::::.:   ::::.: :.::.:: :. 
XP_016 QAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT
              300       310       320       330       340       350

       350                                                         
pF1KE2 RKCLIPF                                                     
                                                                   
XP_016 GEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPS
              360       370       380       390       400       410

>--
 initn: 1077 init1: 858 opt: 863  Z-score: 1011.7  bits: 198.5 E(85289): 1.3e-49
Smith-Waterman score: 863; 59.0% identity (78.0% similar) in 205 aa overlap (149-353:477-681)

      120       130       140       150       160       170        
pF1KE2 KLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAV
                                     ::::::: . .::.:.:: ::.::: .:::
XP_016 TPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAV
        450       460       470       480       490       500      

      180       190       200       210       220       230        
pF1KE2 IATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQET
       ::.:::: :::: :.:::::::: :::::::: .::. : ::: .. :::::: :   ::
XP_016 IASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
        510       520       530       540       550       560      

      240       250       260       270       280       290        
pF1KE2 YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGW
       :::::.::.:.:.::  :   .:::.:: . ::...: :::.:.: :::  :.:.:  ::
XP_016 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGW
        570       580       590       600       610       620      

      300       310       320       330       340       350        
pF1KE2 LSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF    
       :.:.:.:.:... :  :::   ::::.: . ::::.: : ::  :.::.    .:     
XP_016 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEE
        630       640       650       660       670       680      

XP_016 EGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAY
        690       700       710       720       730       740      

>>NP_037359 (OMIM: 155760,165800,608361,612813) aggrecan  (2530 aa)
 initn: 2211 init1: 1140 opt: 1208  Z-score: 1419.6  bits: 274.0 E(85289): 2.5e-72
Smith-Waterman score: 1208; 49.9% identity (77.5% similar) in 355 aa overlap (5-346:1-349)

               10         20                  30        40         
pF1KE2 MFINIKSILWMCSTL-IVTHAL------H----KVKVGKSPPVRGSLSGKVSLPCHF-ST
           . ..::.  :: ..: :.      :    .:.. .  :.:  :. ....::.: . 
NP_037     MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDP
                   10        20        30        40        50      

       50        60         70        80        90       100       
pF1KE2 MPTLPPSYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHP
       :  .  . .:. .  :::::..  .      ::...::: .: ..... :. .::.:..:
NP_037 MHPVTTAPSTAPLAPRIKWSRVSKE------KEVVLLVATEGRVRVNSAYQDKVSLPNYP
         60        70        80              90       100       110

       110       120       130       140       150       160       
pF1KE2 EAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEA
          .::.: : .: ..:.:.:::.::.::::.. :. ..: :.:::::: ..::::.:. 
NP_037 AIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDR
              120       130       140       150       160       170

       170       180       190       200       210       220       
pF1KE2 AQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGV
       ::.:::. .:.::::::: :::::::.::::::::::::::::..:: ::::::    ::
NP_037 AQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGV
              180       190       200       210       220       230

       230       240       250       260       270       280       
pF1KE2 RTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
       ::::.:. .:::::::......:.::. : : ::::.:::.::.   :::::.:.:  ::
NP_037 RTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAW
              240       250       260       270       280       290

       290       300       310       320       330       340       
pF1KE2 RNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK
       . :.:.:. :::.: :::.:.. :: .:::.::::::.:   ::::.: :.::.:: :. 
NP_037 QAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT
              300       310       320       330       340       350

       350                                                         
pF1KE2 RKCLIPF                                                     
                                                                   
NP_037 GEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPS
              360       370       380       390       400       410

>--
 initn: 1077 init1: 858 opt: 863  Z-score: 1011.7  bits: 198.5 E(85289): 1.3e-49
Smith-Waterman score: 863; 59.0% identity (78.0% similar) in 205 aa overlap (149-353:477-681)

      120       130       140       150       160       170        
pF1KE2 KLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAV
                                     ::::::: . .::.:.:: ::.::: .:::
NP_037 TPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAV
        450       460       470       480       490       500      

      180       190       200       210       220       230        
pF1KE2 IATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQET
       ::.:::: :::: :.:::::::: :::::::: .::. : ::: .. :::::: :   ::
NP_037 IASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
        510       520       530       540       550       560      

      240       250       260       270       280       290        
pF1KE2 YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGW
       :::::.::.:.:.::  :   .:::.:: . ::...: :::.:.: :::  :.:.:  ::
NP_037 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGW
        570       580       590       600       610       620      

      300       310       320       330       340       350        
pF1KE2 LSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF    
       :.:.:.:.:... :  :::   ::::.: . ::::.: : ::  :.::.    .:     
NP_037 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEE
        630       640       650       660       670       680      

NP_037 EGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAY
        690       700       710       720       730       740      

>>XP_011519615 (OMIM: 155760,165800,608361,612813) PREDI  (2530 aa)
 initn: 2211 init1: 1140 opt: 1208  Z-score: 1419.6  bits: 274.0 E(85289): 2.5e-72
Smith-Waterman score: 1208; 49.9% identity (77.5% similar) in 355 aa overlap (5-346:1-349)

               10         20                  30        40         
pF1KE2 MFINIKSILWMCSTL-IVTHAL------H----KVKVGKSPPVRGSLSGKVSLPCHF-ST
           . ..::.  :: ..: :.      :    .:.. .  :.:  :. ....::.: . 
XP_011     MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDP
                   10        20        30        40        50      

       50        60         70        80        90       100       
pF1KE2 MPTLPPSYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHP
       :  .  . .:. .  :::::..  .      ::...::: .: ..... :. .::.:..:
XP_011 MHPVTTAPSTAPLAPRIKWSRVSKE------KEVVLLVATEGRVRVNSAYQDKVSLPNYP
         60        70        80              90       100       110

       110       120       130       140       150       160       
pF1KE2 EAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEA
          .::.: : .: ..:.:.:::.::.::::.. :. ..: :.:::::: ..::::.:. 
XP_011 AIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDR
              120       130       140       150       160       170

       170       180       190       200       210       220       
pF1KE2 AQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGV
       ::.:::. .:.::::::: :::::::.::::::::::::::::..:: ::::::    ::
XP_011 AQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGV
              180       190       200       210       220       230

       230       240       250       260       270       280       
pF1KE2 RTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
       ::::.:. .:::::::......:.::. : : ::::.:::.::.   :::::.:.:  ::
XP_011 RTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAW
              240       250       260       270       280       290

       290       300       310       320       330       340       
pF1KE2 RNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK
       . :.:.:. :::.: :::.:.. :: .:::.::::::.:   ::::.: :.::.:: :. 
XP_011 QAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT
              300       310       320       330       340       350

       350                                                         
pF1KE2 RKCLIPF                                                     
                                                                   
XP_011 GEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPS
              360       370       380       390       400       410

>--
 initn: 1077 init1: 858 opt: 863  Z-score: 1011.7  bits: 198.5 E(85289): 1.3e-49
Smith-Waterman score: 863; 59.0% identity (78.0% similar) in 205 aa overlap (149-353:477-681)

      120       130       140       150       160       170        
pF1KE2 KLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAV
                                     ::::::: . .::.:.:: ::.::: .:::
XP_011 TPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAV
        450       460       470       480       490       500      

      180       190       200       210       220       230        
pF1KE2 IATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQET
       ::.:::: :::: :.:::::::: :::::::: .::. : ::: .. :::::: :   ::
XP_011 IASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
        510       520       530       540       550       560      

      240       250       260       270       280       290        
pF1KE2 YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGW
       :::::.::.:.:.::  :   .:::.:: . ::...: :::.:.: :::  :.:.:  ::
XP_011 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGW
        570       580       590       600       610       620      

      300       310       320       330       340       350        
pF1KE2 LSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF    
       :.:.:.:.:... :  :::   ::::.: . ::::.: : ::  :.::.    .:     
XP_011 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEE
        630       640       650       660       670       680      

XP_011 EGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAY
        690       700       710       720       730       740      

>>XP_016877474 (OMIM: 155760,165800,608361,612813) PREDI  (2553 aa)
 initn: 2211 init1: 1140 opt: 1208  Z-score: 1419.5  bits: 274.0 E(85289): 2.5e-72
Smith-Waterman score: 1208; 49.9% identity (77.5% similar) in 355 aa overlap (5-346:1-349)

               10         20                  30        40         
pF1KE2 MFINIKSILWMCSTL-IVTHAL------H----KVKVGKSPPVRGSLSGKVSLPCHF-ST
           . ..::.  :: ..: :.      :    .:.. .  :.:  :. ....::.: . 
XP_016     MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDP
                   10        20        30        40        50      

       50        60         70        80        90       100       
pF1KE2 MPTLPPSYNTSEFL-RIKWSKIEVDKNGKDLKETTVLVAQNGNIKIGQDYKGRVSVPTHP
       :  .  . .:. .  :::::..  .      ::...::: .: ..... :. .::.:..:
XP_016 MHPVTTAPSTAPLAPRIKWSRVSKE------KEVVLLVATEGRVRVNSAYQDKVSLPNYP
         60        70        80              90       100       110

       110       120       130       140       150       160       
pF1KE2 EAVGDASLTVVKLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEA
          .::.: : .: ..:.:.:::.::.::::.. :. ..: :.:::::: ..::::.:. 
XP_016 AIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDR
              120       130       140       150       160       170

       170       180       190       200       210       220       
pF1KE2 AQKACLDVGAVIATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGV
       ::.:::. .:.::::::: :::::::.::::::::::::::::..:: ::::::    ::
XP_016 AQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGV
              180       190       200       210       220       230

       230       240       250       260       270       280       
pF1KE2 RTYGFRSPQETYDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAW
       ::::.:. .:::::::......:.::. : : ::::.:::.::.   :::::.:.:  ::
XP_016 RTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAW
              240       250       260       270       280       290

       290       300       310       320       330       340       
pF1KE2 RNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFK
       . :.:.:. :::.: :::.:.. :: .:::.::::::.:   ::::.: :.::.:: :. 
XP_016 QAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYT
              300       310       320       330       340       350

       350                                                         
pF1KE2 RKCLIPF                                                     
                                                                   
XP_016 GEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPS
              360       370       380       390       400       410

>--
 initn: 1077 init1: 858 opt: 863  Z-score: 1011.6  bits: 198.5 E(85289): 1.3e-49
Smith-Waterman score: 863; 59.0% identity (78.0% similar) in 205 aa overlap (149-353:477-681)

      120       130       140       150       160       170        
pF1KE2 KLLASDAGLYRCDVMYGIEDTQDTVSLTVDGVVFHYRAATSRYTLNFEAAQKACLDVGAV
                                     ::::::: . .::.:.:: ::.::: .:::
XP_016 TPGLGPATAFTSEDLVVQVTAVPGQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAV
        450       460       470       480       490       500      

      180       190       200       210       220       230        
pF1KE2 IATPEQLFAAYEDGFEQCDAGWLADQTVRYPIRAPRVGCYGDKMGKAGVRTYGFRSPQET
       ::.:::: :::: :.:::::::: :::::::: .::. : ::: .. :::::: :   ::
XP_016 IASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTET
        510       520       530       540       550       560      

      240       250       260       270       280       290        
pF1KE2 YDVYCYVDHLDGDVFHLTVPSKFTFEEAAKECENQDARLATVGELQAAWRNGFDQCDYGW
       :::::.::.:.:.::  :   .:::.:: . ::...: :::.:.: :::  :.:.:  ::
XP_016 YDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGW
        570       580       590       600       610       620      

      300       310       320       330       340       350        
pF1KE2 LSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTGFPPPDSRFDAYCFKRKCLIPF    
       :.:.:.:.:... :  :::   ::::.: . ::::.: : ::  :.::.    .:     
XP_016 LADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEE
        630       640       650       660       670       680      

XP_016 EGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAY
        690       700       710       720       730       740      




354 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 17:35:31 2016 done: Tue Nov  8 17:35:32 2016
 Total Scan time:  6.400 Total Display time:  0.030

Function used was FASTA [36.3.4 Apr, 2011]
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