FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2640, 394 aa 1>>>pF1KE2640 394 - 394 aa - 394 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0025+/-0.000907; mu= 14.5977+/- 0.055 mean_var=101.5657+/-20.919, 0's: 0 Z-trim(108.4): 43 B-trim: 0 in 0/51 Lambda= 0.127263 statistics sampled from 10185 (10218) to 10185 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.664), E-opt: 0.2 (0.314), width: 16 Scan time: 1.830 The best scores are: opt bits E(32554) CCDS1727.1 KCNK3 gene_id:3777|Hs108|chr2 ( 394) 2605 488.8 3.7e-138 CCDS6377.1 KCNK9 gene_id:51305|Hs108|chr8 ( 374) 1329 254.5 1.2e-67 CCDS13337.1 KCNK15 gene_id:60598|Hs108|chr20 ( 330) 1077 208.2 9.2e-54 CCDS4841.1 KCNK5 gene_id:8645|Hs108|chr6 ( 499) 397 83.5 4.8e-16 CCDS9880.1 KCNK10 gene_id:54207|Hs108|chr14 ( 538) 394 82.9 7.5e-16 CCDS9881.1 KCNK10 gene_id:54207|Hs108|chr14 ( 543) 394 82.9 7.6e-16 CCDS9882.1 KCNK10 gene_id:54207|Hs108|chr14 ( 543) 394 82.9 7.6e-16 CCDS31024.1 KCNK2 gene_id:3776|Hs108|chr1 ( 411) 391 82.3 9e-16 CCDS41466.1 KCNK2 gene_id:3776|Hs108|chr1 ( 422) 391 82.3 9.1e-16 CCDS41467.1 KCNK2 gene_id:3776|Hs108|chr1 ( 426) 391 82.3 9.2e-16 CCDS47422.1 KCNK16 gene_id:83795|Hs108|chr6 ( 294) 383 80.7 1.9e-15 CCDS4843.1 KCNK16 gene_id:83795|Hs108|chr6 ( 309) 383 80.7 2e-15 CCDS1599.1 KCNK1 gene_id:3775|Hs108|chr1 ( 336) 379 80.0 3.5e-15 CCDS47420.1 KCNK16 gene_id:83795|Hs108|chr6 ( 262) 363 77.0 2.2e-14 CCDS47421.1 KCNK16 gene_id:83795|Hs108|chr6 ( 322) 362 76.9 3e-14 CCDS12513.1 KCNK6 gene_id:9424|Hs108|chr19 ( 313) 357 75.9 5.5e-14 CCDS8067.1 KCNK4 gene_id:50801|Hs108|chr11 ( 393) 350 74.7 1.6e-13 CCDS4842.1 KCNK17 gene_id:89822|Hs108|chr6 ( 332) 344 73.6 3e-13 CCDS47419.1 KCNK17 gene_id:89822|Hs108|chr6 ( 271) 330 70.9 1.5e-12 CCDS9889.1 KCNK13 gene_id:56659|Hs108|chr14 ( 408) 306 66.7 4.4e-11 >>CCDS1727.1 KCNK3 gene_id:3777|Hs108|chr2 (394 aa) initn: 2605 init1: 2605 opt: 2605 Z-score: 2593.8 bits: 488.8 E(32554): 3.7e-138 Smith-Waterman score: 2605; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394) 10 20 30 40 50 60 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KE2 AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS17 AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR 310 320 330 340 350 360 370 380 390 pF1KE2 CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV :::::::::::::::::::::::::::::::::: CCDS17 CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV 370 380 390 >>CCDS6377.1 KCNK9 gene_id:51305|Hs108|chr8 (374 aa) initn: 1442 init1: 1329 opt: 1329 Z-score: 1328.0 bits: 254.5 E(32554): 1.2e-67 Smith-Waterman score: 1415; 59.2% identity (77.5% similar) in 395 aa overlap (1-394:1-374) 10 20 30 40 50 60 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE :::::::::.:::::::::::::::::::::. :. :...:. .. .....::.:. :. CCDS63 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL .:: :.:. .::.:::::.::::::::::::::::::::::.::.::.::::::.::::: CCDS63 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH :::::::::::.::.:::::.: :: ::: .:::: ::: .:::::..::::::::::. CCDS63 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KE2 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN :.:.::.::::::::::::::::::::: ::: .: ::::::.:::.:::::::::: CCDS63 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KE2 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY ::::::.:::.:::.::::.:: :. :. .. : . . : : CCDS63 LVVLRFLTMNSEDERRDAEERASLA------GNRNSMVIHIPEEPRPS--------RPRY 250 260 270 280 310 320 330 340 350 pF1KE2 -AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSR :.: .::.::: :.:.. :. . :.. .. . :: . : . . CCDS63 KADVPDLQSVCSCTCYRSQD---YGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLK 290 300 310 320 330 340 360 370 380 390 pF1KE2 RCLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV : : : :::.: ::::.. . :::::.:: CCDS63 NSLF---P-SPISSISPGLHSFTDHQRLMKRRKSV 350 360 370 >>CCDS13337.1 KCNK15 gene_id:60598|Hs108|chr20 (330 aa) initn: 1078 init1: 1051 opt: 1077 Z-score: 1078.7 bits: 208.2 E(32554): 9.2e-54 Smith-Waterman score: 1077; 65.3% identity (84.2% similar) in 259 aa overlap (1-258:1-258) 10 20 30 40 50 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQ-ELRARYNLSQGGY :.: .::. .:..::. ::::::::::::::: : :::: .... :: ....: : CCDS13 MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAES-GRQRLLVQKRGALRRKFGFSAEDY 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 EELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIP .::::..:. .::.:: ::.: ::::::::::::: ::::::.::.:::::::::::::: CCDS13 RELERLALQAEPHRAGRQWKFPGSFYFAITVITTIEYGHAAPGTDSGKVFCMFYALLGIP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 LTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFS :::: :::::::.:..:: :: :: ::.: . :: :.:. :...: .:: .::.::: CCDS13 LTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KE2 HYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFL :.: ::::.::::::::::::::::.::::. .::: . ::::::.::: ::::::::: CCDS13 HFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KE2 NLVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNV :::::::.. .:. .: : CCDS13 NLVVLRFLVASADWPERAARTPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERC 240 250 260 270 280 290 >>CCDS4841.1 KCNK5 gene_id:8645|Hs108|chr6 (499 aa) initn: 371 init1: 201 opt: 397 Z-score: 401.5 bits: 83.5 E(32554): 4.8e-16 Smith-Waterman score: 410; 32.5% identity (64.7% similar) in 252 aa overlap (18-256:15-259) 10 20 30 40 50 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQE--LRARYNLSQGG :: .:::.:..:: ::. : .. :. :. :.: : CCDS48 MVDRGPLLTSAIIFYLAIGAAIFEVLE-EPHWKEAKKNYYTQKLHLLKEFPCLGQEG 10 20 30 40 50 60 70 80 90 100 110 pF1KE2 YEELERVV-------LRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCM ... .:: . . ... .: . ... :: :::::::::..::.: .:..::. CCDS48 LDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCV 60 70 80 90 100 110 120 130 140 150 160 pF1KE2 FYALLGIPLTLVMFQSLGE----RINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSC ::.:.:.:: :. ...::. : . : ..: .:.:...:.:... . . .. .. CCDS48 FYGLFGVPLCLTWISALGKFFGGRAKRLGQFL---TKRGVSLRKAQITCTVIFIV--WGV 120 130 140 150 160 170 170 180 190 200 210 220 pF1KE2 ISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVY . : : .: : :..... :: :::..::::::.:: . .: . . : : .. CCDS48 LVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSA-NYHALYRYFVELW 180 190 200 210 220 230 230 240 250 260 270 280 pF1KE2 ILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASS : ::. .. :.: : :. .. .:: CCDS48 IYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNI 240 250 260 270 280 290 >>CCDS9880.1 KCNK10 gene_id:54207|Hs108|chr14 (538 aa) initn: 403 init1: 235 opt: 394 Z-score: 398.1 bits: 82.9 E(32554): 7.5e-16 Smith-Waterman score: 448; 33.2% identity (66.8% similar) in 274 aa overlap (1-254:67-332) 10 20 30 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALE :: ..: .:..: . .::..:. :: ::: CCDS98 PTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV--VAIFVVVVVYLVTGGLVFRALE 40 50 60 70 80 90 40 50 60 70 pF1KE2 SEPELIERQRLELRQQE-LRARYNLSQGGYEELERVVLR-LKPHKAGV-----------Q . : ... . :.. : :: . .: .::: .. . : .::: . CCDS98 QPFESSQKNTIALEKAEFLRDHVCVSP---QELETLIQHALDADNAGVSPIGNSSNNSSH 100 110 120 130 140 150 80 90 100 110 120 130 pF1KE2 WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVR : ....:.:: :::::::::. ::::.:::.::..::..:::: .. ..:....:. CCDS98 WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFG 160 170 180 190 200 210 140 150 160 170 180 190 pF1KE2 YLLHRAKKGLGMRRADVSMANM-----VLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYY . :..: . :. .::.... .:. . .:: . : :. :.. : :: ... :. CCDS98 KSIARVEKVF--RKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYF 220 230 240 250 260 200 210 220 230 240 250 pF1KE2 CFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV--VLRFMTMN .::::.::::.:: . ... . : . . .::.::. ..: :... :: .. . CCDS98 VVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKK 270 280 290 300 310 320 260 270 280 290 300 310 pF1KE2 AEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMC ...: CCDS98 TKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHS 330 340 350 360 370 380 >>CCDS9881.1 KCNK10 gene_id:54207|Hs108|chr14 (543 aa) initn: 403 init1: 235 opt: 394 Z-score: 398.0 bits: 82.9 E(32554): 7.6e-16 Smith-Waterman score: 448; 33.2% identity (66.8% similar) in 274 aa overlap (1-254:72-337) 10 20 30 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALE :: ..: .:..: . .::..:. :: ::: CCDS98 PTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV--VAIFVVVVVYLVTGGLVFRALE 50 60 70 80 90 40 50 60 70 pF1KE2 SEPELIERQRLELRQQE-LRARYNLSQGGYEELERVVLR-LKPHKAGV-----------Q . : ... . :.. : :: . .: .::: .. . : .::: . CCDS98 QPFESSQKNTIALEKAEFLRDHVCVSP---QELETLIQHALDADNAGVSPIGNSSNNSSH 100 110 120 130 140 150 80 90 100 110 120 130 pF1KE2 WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVR : ....:.:: :::::::::. ::::.:::.::..::..:::: .. ..:....:. CCDS98 WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFG 160 170 180 190 200 210 140 150 160 170 180 190 pF1KE2 YLLHRAKKGLGMRRADVSMANM-----VLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYY . :..: . :. .::.... .:. . .:: . : :. :.. : :: ... :. CCDS98 KSIARVEKVF--RKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYF 220 230 240 250 260 270 200 210 220 230 240 250 pF1KE2 CFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV--VLRFMTMN .::::.::::.:: . ... . : . . .::.::. ..: :... :: .. . CCDS98 VVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKK 280 290 300 310 320 330 260 270 280 290 300 310 pF1KE2 AEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMC ...: CCDS98 TKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHS 340 350 360 370 380 390 >>CCDS9882.1 KCNK10 gene_id:54207|Hs108|chr14 (543 aa) initn: 403 init1: 235 opt: 394 Z-score: 398.0 bits: 82.9 E(32554): 7.6e-16 Smith-Waterman score: 448; 33.2% identity (66.8% similar) in 274 aa overlap (1-254:72-337) 10 20 30 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALE :: ..: .:..: . .::..:. :: ::: CCDS98 PTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV--VAIFVVVVVYLVTGGLVFRALE 50 60 70 80 90 40 50 60 70 pF1KE2 SEPELIERQRLELRQQE-LRARYNLSQGGYEELERVVLR-LKPHKAGV-----------Q . : ... . :.. : :: . .: .::: .. . : .::: . CCDS98 QPFESSQKNTIALEKAEFLRDHVCVSP---QELETLIQHALDADNAGVSPIGNSSNNSSH 100 110 120 130 140 150 80 90 100 110 120 130 pF1KE2 WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVR : ....:.:: :::::::::. ::::.:::.::..::..:::: .. ..:....:. CCDS98 WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFG 160 170 180 190 200 210 140 150 160 170 180 190 pF1KE2 YLLHRAKKGLGMRRADVSMANM-----VLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYY . :..: . :. .::.... .:. . .:: . : :. :.. : :: ... :. CCDS98 KSIARVEKVF--RKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYF 220 230 240 250 260 270 200 210 220 230 240 250 pF1KE2 CFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV--VLRFMTMN .::::.::::.:: . ... . : . . .::.::. ..: :... :: .. . CCDS98 VVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKK 280 290 300 310 320 330 260 270 280 290 300 310 pF1KE2 AEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMC ...: CCDS98 TKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAHS 340 350 360 370 380 390 >>CCDS31024.1 KCNK2 gene_id:3776|Hs108|chr1 (411 aa) initn: 396 init1: 208 opt: 391 Z-score: 396.7 bits: 82.3 E(32554): 9e-16 Smith-Waterman score: 457; 31.4% identity (65.7% similar) in 271 aa overlap (1-254:42-306) 10 20 30 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALE :: ..: :. :.: ::..::.:: ::: CCDS31 AAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVL--YLIIGATVFKALE 20 30 40 50 60 40 50 60 70 pF1KE2 SEPELIERQRLELRQQELRARYNLSQGGYEELERVVLRLKPH-KAGV-----------QW . :. .: . ...: . .... .. ::.... .. .::. .: CCDS31 QPHEISQRTTIVIQKQTFISQHSCVNS--TELDELIQQIVAAINAGIIPLGNTSNQISHW 70 80 90 100 110 120 80 90 100 110 120 130 pF1KE2 RFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRY ...::.:: :::::::.:. .: :.:::.::..:::::::: .. ..:....:. CCDS31 DLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGK 130 140 150 160 170 180 140 150 160 170 180 190 pF1KE2 LLHRAKKGL---GMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFI . ... . .. .. . . . ... .:.:. . . : :.: : :. ..: :. : CCDS31 GIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVI 190 200 210 220 230 240 200 210 220 230 240 250 pF1KE2 TLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV--VLRFMTMNAED :::::::::::: .: .. : . .::.::. ..: :... :: .. .... CCDS31 TLTTIGFGDYVAGGSD--IEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKE 250 260 270 280 290 300 260 270 280 290 300 310 pF1KE2 EKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCL : CCDS31 EVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPC 310 320 330 340 350 360 >>CCDS41466.1 KCNK2 gene_id:3776|Hs108|chr1 (422 aa) initn: 396 init1: 208 opt: 391 Z-score: 396.5 bits: 82.3 E(32554): 9.1e-16 Smith-Waterman score: 457; 31.4% identity (65.7% similar) in 271 aa overlap (1-254:53-317) 10 20 30 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALE :: ..: :. :.: ::..::.:: ::: CCDS41 AAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVL--YLIIGATVFKALE 30 40 50 60 70 80 40 50 60 70 pF1KE2 SEPELIERQRLELRQQELRARYNLSQGGYEELERVVLRLKPH-KAGV-----------QW . :. .: . ...: . .... .. ::.... .. .::. .: CCDS41 QPHEISQRTTIVIQKQTFISQHSCVNS--TELDELIQQIVAAINAGIIPLGNTSNQISHW 90 100 110 120 130 80 90 100 110 120 130 pF1KE2 RFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRY ...::.:: :::::::.:. .: :.:::.::..:::::::: .. ..:....:. CCDS41 DLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGK 140 150 160 170 180 190 140 150 160 170 180 190 pF1KE2 LLHRAKKGL---GMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFI . ... . .. .. . . . ... .:.:. . . : :.: : :. ..: :. : CCDS41 GIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVI 200 210 220 230 240 250 200 210 220 230 240 250 pF1KE2 TLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV--VLRFMTMNAED :::::::::::: .: .. : . .::.::. ..: :... :: .. .... CCDS41 TLTTIGFGDYVAGGSD--IEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKE 260 270 280 290 300 310 260 270 280 290 300 310 pF1KE2 EKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCL : CCDS41 EVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPC 320 330 340 350 360 370 >>CCDS41467.1 KCNK2 gene_id:3776|Hs108|chr1 (426 aa) initn: 396 init1: 208 opt: 391 Z-score: 396.5 bits: 82.3 E(32554): 9.2e-16 Smith-Waterman score: 457; 31.4% identity (65.7% similar) in 271 aa overlap (1-254:57-321) 10 20 30 pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALE :: ..: :. :.: ::..::.:: ::: CCDS41 AAQNSKPRLSFSTKPTVLASRVESDTTINVMKWKTVSTIFLVVVL--YLIIGATVFKALE 30 40 50 60 70 80 40 50 60 70 pF1KE2 SEPELIERQRLELRQQELRARYNLSQGGYEELERVVLRLKPH-KAGV-----------QW . :. .: . ...: . .... .. ::.... .. .::. .: CCDS41 QPHEISQRTTIVIQKQTFISQHSCVNS--TELDELIQQIVAAINAGIIPLGNTSNQISHW 90 100 110 120 130 140 80 90 100 110 120 130 pF1KE2 RFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRY ...::.:: :::::::.:. .: :.:::.::..:::::::: .. ..:....:. CCDS41 DLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLFGFLLAGVGDQLGTIFGK 150 160 170 180 190 200 140 150 160 170 180 190 pF1KE2 LLHRAKKGL---GMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFI . ... . .. .. . . . ... .:.:. . . : :.: : :. ..: :. : CCDS41 GIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSALDAIYFVVI 210 220 230 240 250 260 200 210 220 230 240 250 pF1KE2 TLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLV--VLRFMTMNAED :::::::::::: .: .. : . .::.::. ..: :... :: .. .... CCDS41 TLTTIGFGDYVAGGSD--IEYLDFYKPVVWFWILVGLAYFAAVLSMIGDWLRVISKKTKE 270 280 290 300 310 320 260 270 280 290 300 310 pF1KE2 EKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCL : CCDS41 EVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIKRKLSAELAGNHNQELTPC 330 340 350 360 370 380 394 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Tue Nov 8 17:39:52 2016 done: Tue Nov 8 17:39:53 2016 Total Scan time: 1.830 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]