Result of FASTA (omim) for
pF1KE2640
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2640, 394 aa
1>>>pF1KE2640 394 - 394 aa - 394 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6951+/-0.00037; mu= 16.0454+/- 0.023
mean_var=99.5820+/-20.341, 0's: 0 Z-trim(115.4): 71 B-trim: 0 in 0/52
Lambda= 0.128524
statistics sampled from 25680 (25756) to 25680 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.302), width: 16
Scan time: 6.730
The best scores are: opt bits E(85289)
NP_002237 (OMIM: 603220,615344) potassium channel ( 394) 2605 493.5 3.6e-139
XP_005264350 (OMIM: 603220,615344) PREDICTED: pota ( 284) 1887 360.3 3.3e-99
XP_011515404 (OMIM: 605874,612292) PREDICTED: pota ( 374) 1329 256.9 5.7e-68
NP_001269463 (OMIM: 605874,612292) potassium chann ( 374) 1329 256.9 5.7e-68
XP_011515403 (OMIM: 605874,612292) PREDICTED: pota ( 401) 1329 256.9 6e-68
NP_071753 (OMIM: 607368) potassium channel subfami ( 330) 1077 210.1 6.1e-54
XP_016869020 (OMIM: 605874,612292) PREDICTED: pota ( 264) 809 160.4 4.7e-39
XP_016869019 (OMIM: 605874,612292) PREDICTED: pota ( 264) 809 160.4 4.7e-39
XP_011515405 (OMIM: 605874,612292) PREDICTED: pota ( 291) 809 160.4 5e-39
NP_003731 (OMIM: 603493) potassium channel subfami ( 499) 397 84.2 7.4e-16
XP_011535142 (OMIM: 605873) PREDICTED: potassium c ( 410) 394 83.6 9.5e-16
NP_066984 (OMIM: 605873) potassium channel subfami ( 538) 394 83.7 1.2e-15
NP_612190 (OMIM: 605873) potassium channel subfami ( 543) 394 83.7 1.2e-15
NP_612191 (OMIM: 605873) potassium channel subfami ( 543) 394 83.7 1.2e-15
XP_011507824 (OMIM: 603219) PREDICTED: potassium c ( 370) 391 83.0 1.3e-15
XP_011507826 (OMIM: 603219) PREDICTED: potassium c ( 370) 391 83.0 1.3e-15
XP_011507825 (OMIM: 603219) PREDICTED: potassium c ( 370) 391 83.0 1.3e-15
NP_055032 (OMIM: 603219) potassium channel subfami ( 411) 391 83.0 1.4e-15
XP_016856738 (OMIM: 603219) PREDICTED: potassium c ( 412) 391 83.0 1.4e-15
XP_016856737 (OMIM: 603219) PREDICTED: potassium c ( 422) 391 83.0 1.4e-15
NP_001017424 (OMIM: 603219) potassium channel subf ( 422) 391 83.0 1.4e-15
NP_001017425 (OMIM: 603219) potassium channel subf ( 426) 391 83.0 1.4e-15
NP_001128578 (OMIM: 607369) potassium channel subf ( 294) 383 81.4 3.1e-15
NP_115491 (OMIM: 607369) potassium channel subfami ( 309) 383 81.4 3.2e-15
NP_002236 (OMIM: 601745) potassium channel subfami ( 336) 379 80.7 5.6e-15
XP_005249513 (OMIM: 603493) PREDICTED: potassium c ( 496) 377 80.5 9.7e-15
XP_011513237 (OMIM: 607369) PREDICTED: potassium c ( 197) 363 77.6 3e-14
NP_001128579 (OMIM: 607369) potassium channel subf ( 262) 363 77.7 3.7e-14
XP_016866835 (OMIM: 607369) PREDICTED: potassium c ( 262) 363 77.7 3.7e-14
NP_001128577 (OMIM: 607369) potassium channel subf ( 322) 362 77.6 4.8e-14
XP_016883492 (OMIM: 607368) PREDICTED: potassium c ( 218) 357 76.5 6.9e-14
NP_004814 (OMIM: 603939) potassium channel subfami ( 313) 357 76.6 9e-14
NP_001304019 (OMIM: 605720) potassium channel subf ( 393) 350 75.4 2.6e-13
NP_201567 (OMIM: 605720) potassium channel subfami ( 393) 350 75.4 2.6e-13
NP_113648 (OMIM: 607370) potassium channel subfami ( 332) 344 74.2 5e-13
NP_001128583 (OMIM: 607370) potassium channel subf ( 271) 330 71.6 2.6e-12
XP_011542486 (OMIM: 601745) PREDICTED: potassium c ( 268) 323 70.3 6.4e-12
NP_071337 (OMIM: 607367) potassium channel subfami ( 408) 306 67.3 7.7e-11
NP_258416 (OMIM: 603940) potassium channel subfami ( 252) 240 54.8 2.6e-07
NP_203134 (OMIM: 603940) potassium channel subfami ( 252) 240 54.8 2.6e-07
NP_005705 (OMIM: 603940) potassium channel subfami ( 257) 240 54.9 2.7e-07
NP_203133 (OMIM: 603940) potassium channel subfami ( 307) 240 54.9 3e-07
NP_862823 (OMIM: 613655,613656) potassium channel ( 384) 241 55.2 3.1e-07
NP_071338 (OMIM: 607366) potassium channel subfami ( 430) 236 54.3 6.5e-07
XP_011525828 (OMIM: 603939) PREDICTED: potassium c ( 179) 176 42.8 0.00076
>>NP_002237 (OMIM: 603220,615344) potassium channel subf (394 aa)
initn: 2605 init1: 2605 opt: 2605 Z-score: 2619.6 bits: 493.5 E(85289): 3.6e-139
Smith-Waterman score: 2605; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRR
310 320 330 340 350 360
370 380 390
pF1KE2 CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV
::::::::::::::::::::::::::::::::::
NP_002 CLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV
370 380 390
>>XP_005264350 (OMIM: 603220,615344) PREDICTED: potassiu (284 aa)
initn: 1887 init1: 1887 opt: 1887 Z-score: 1902.0 bits: 360.3 E(85289): 3.3e-99
Smith-Waterman score: 1887; 100.0% identity (100.0% similar) in 284 aa overlap (111-394:1-284)
90 100 110 120 130 140
pF1KE2 AGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLL
::::::::::::::::::::::::::::::
XP_005 MFYALLGIPLTLVMFQSLGERINTLVRYLL
10 20 30
150 160 170 180 190 200
pF1KE2 HRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE2 GFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEH
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE2 RALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCLWYKSREK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCLWYKSREK
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE2 LQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLHS
220 230 240 250 260 270
390
pF1KE2 LSTFRGLMKRRSSV
::::::::::::::
XP_005 LSTFRGLMKRRSSV
280
>>XP_011515404 (OMIM: 605874,612292) PREDICTED: potassiu (374 aa)
initn: 1442 init1: 1329 opt: 1329 Z-score: 1341.2 bits: 256.9 E(85289): 5.7e-68
Smith-Waterman score: 1415; 59.2% identity (77.5% similar) in 395 aa overlap (1-394:1-374)
10 20 30 40 50 60
pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE
:::::::::.:::::::::::::::::::::. :. :...:. .. .....::.:. :.
XP_011 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL
.:: :.:. .::.:::::.::::::::::::::::::::::.::.::.::::::.:::::
XP_011 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH
:::::::::::.::.:::::.: :: ::: .:::: ::: .:::::..::::::::::.
XP_011 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN
:.:.::.::::::::::::::::::::: ::: .: ::::::.:::.::::::::::
XP_011 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY
::::::.:::.:::.::::.:: :. :. .. : . . : :
XP_011 LVVLRFLTMNSEDERRDAEERASLA------GNRNSMVIHIPEEPRPS--------RPRY
250 260 270 280
310 320 330 340 350
pF1KE2 -AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSR
:.: .::.::: :.:.. :. . :.. .. . :: . : . .
XP_011 KADVPDLQSVCSCTCYRSQD---YGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLK
290 300 310 320 330 340
360 370 380 390
pF1KE2 RCLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV
: : : :::.: ::::.. . :::::.::
XP_011 NSLF---P-SPISSISPGLHSFTDHQRLMKRRKSV
350 360 370
>>NP_001269463 (OMIM: 605874,612292) potassium channel s (374 aa)
initn: 1442 init1: 1329 opt: 1329 Z-score: 1341.2 bits: 256.9 E(85289): 5.7e-68
Smith-Waterman score: 1415; 59.2% identity (77.5% similar) in 395 aa overlap (1-394:1-374)
10 20 30 40 50 60
pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE
:::::::::.:::::::::::::::::::::. :. :...:. .. .....::.:. :.
NP_001 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL
.:: :.:. .::.:::::.::::::::::::::::::::::.::.::.::::::.:::::
NP_001 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH
:::::::::::.::.:::::.: :: ::: .:::: ::: .:::::..::::::::::.
NP_001 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN
:.:.::.::::::::::::::::::::: ::: .: ::::::.:::.::::::::::
NP_001 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY
::::::.:::.:::.::::.:: :. :. .. : . . : :
NP_001 LVVLRFLTMNSEDERRDAEERASLA------GNRNSMVIHIPEEPRPS--------RPRY
250 260 270 280
310 320 330 340 350
pF1KE2 -AEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSR
:.: .::.::: :.:.. :. . :.. .. . :: . : . .
NP_001 KADVPDLQSVCSCTCYRSQD---YGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLK
290 300 310 320 330 340
360 370 380 390
pF1KE2 RCLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV
: : : :::.: ::::.. . :::::.::
NP_001 NSLF---P-SPISSISPGLHSFTDHQRLMKRRKSV
350 360 370
>>XP_011515403 (OMIM: 605874,612292) PREDICTED: potassiu (401 aa)
initn: 1354 init1: 1329 opt: 1329 Z-score: 1340.8 bits: 256.9 E(85289): 6e-68
Smith-Waterman score: 1329; 74.5% identity (91.8% similar) in 267 aa overlap (1-267:1-267)
10 20 30 40 50 60
pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE
:::::::::.:::::::::::::::::::::. :. :...:. .. .....::.:. :.
XP_011 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL
.:: :.:. .::.:::::.::::::::::::::::::::::.::.::.::::::.:::::
XP_011 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH
:::::::::::.::.:::::.: :: ::: .:::: ::: .:::::..::::::::::.
XP_011 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN
:.:.::.::::::::::::::::::::: ::: .: ::::::.:::.::::::::::
XP_011 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 LVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY
::::::.:::.:::.::::.:: :. :
XP_011 LVVLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRGTNCTFKRGVRGCWV
250 260 270 280 290 300
>>NP_071753 (OMIM: 607368) potassium channel subfamily K (330 aa)
initn: 1078 init1: 1051 opt: 1077 Z-score: 1089.4 bits: 210.1 E(85289): 6.1e-54
Smith-Waterman score: 1077; 65.3% identity (84.2% similar) in 259 aa overlap (1-258:1-258)
10 20 30 40 50
pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQ-ELRARYNLSQGGY
:.: .::. .:..::. ::::::::::::::: : :::: .... :: ....: :
NP_071 MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAES-GRQRLLVQKRGALRRKFGFSAEDY
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 EELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIP
.::::..:. .::.:: ::.: ::::::::::::: ::::::.::.::::::::::::::
NP_071 RELERLALQAEPHRAGRQWKFPGSFYFAITVITTIEYGHAAPGTDSGKVFCMFYALLGIP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE2 LTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFS
:::: :::::::.:..:: :: :: ::.: . :: :.:. :...: .:: .::.:::
NP_071 LTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE2 HYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFL
:.: ::::.::::::::::::::::.::::. .::: . ::::::.::: :::::::::
NP_071 HFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE2 NLVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNV
:::::::.. .:. .: :
NP_071 NLVVLRFLVASADWPERAARTPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERC
240 250 260 270 280 290
>>XP_016869020 (OMIM: 605874,612292) PREDICTED: potassiu (264 aa)
initn: 922 init1: 809 opt: 809 Z-score: 822.1 bits: 160.4 E(85289): 4.7e-39
Smith-Waterman score: 895; 55.4% identity (71.6% similar) in 285 aa overlap (111-394:1-264)
90 100 110 120 130 140
pF1KE2 AGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLL
::::.::::::::::::::::.::.:::::
XP_016 MFYAVLGIPLTLVMFQSLGERMNTFVRYLL
10 20 30
150 160 170 180 190 200
pF1KE2 HRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTI
.: :: ::: .:::: ::: .:::::..::::::::::. :.:.::.::::::::::::
XP_016 KRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE2 GFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEH
::::::::: ::: .: ::::::.:::.::::::::::::::::.:::.:::.::::.
XP_016 GFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEE
100 110 120 130 140 150
270 280 290 300 310
pF1KE2 RALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY-AEVLHFQSMCSCLWYKSRE
:: :. :. .. : . . : : :.: .::.::: :.:..
XP_016 RASLA------GNRNSMVIHIPEEPRPS--------RPRYKADVPDLQSVCSCTCYRSQD
160 170 180 190
320 330 340 350 360 370
pF1KE2 KLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLH
:. . :.. .. . :: . : . . : : : :::.: :::
XP_016 ---YGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLF---P-SPISSISPGLH
200 210 220 230 240
380 390
pF1KE2 SLSTFRGLMKRRSSV
:.. . :::::.::
XP_016 SFTDHQRLMKRRKSV
250 260
>>XP_016869019 (OMIM: 605874,612292) PREDICTED: potassiu (264 aa)
initn: 922 init1: 809 opt: 809 Z-score: 822.1 bits: 160.4 E(85289): 4.7e-39
Smith-Waterman score: 895; 55.4% identity (71.6% similar) in 285 aa overlap (111-394:1-264)
90 100 110 120 130 140
pF1KE2 AGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLL
::::.::::::::::::::::.::.:::::
XP_016 MFYAVLGIPLTLVMFQSLGERMNTFVRYLL
10 20 30
150 160 170 180 190 200
pF1KE2 HRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTI
.: :: ::: .:::: ::: .:::::..::::::::::. :.:.::.::::::::::::
XP_016 KRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE2 GFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEH
::::::::: ::: .: ::::::.:::.::::::::::::::::.:::.:::.::::.
XP_016 GFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEE
100 110 120 130 140 150
270 280 290 300 310
pF1KE2 RALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVY-AEVLHFQSMCSCLWYKSRE
:: :. :. .. : . . : : :.: .::.::: :.:..
XP_016 RASLA------GNRNSMVIHIPEEPRPS--------RPRYKADVPDLQSVCSCTCYRSQD
160 170 180 190
320 330 340 350 360 370
pF1KE2 KLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLH
:. . :.. .. . :: . : . . : : : :::.: :::
XP_016 ---YGGRSVAPQNSFSAKLAPHYFHSISYKIEEISPSTLKNSLF---P-SPISSISPGLH
200 210 220 230 240
380 390
pF1KE2 SLSTFRGLMKRRSSV
:.. . :::::.::
XP_016 SFTDHQRLMKRRKSV
250 260
>>XP_011515405 (OMIM: 605874,612292) PREDICTED: potassiu (291 aa)
initn: 809 init1: 809 opt: 809 Z-score: 821.6 bits: 160.4 E(85289): 5e-39
Smith-Waterman score: 809; 78.3% identity (91.1% similar) in 157 aa overlap (111-267:1-157)
90 100 110 120 130 140
pF1KE2 AGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLL
::::.::::::::::::::::.::.:::::
XP_011 MFYAVLGIPLTLVMFQSLGERMNTFVRYLL
10 20 30
150 160 170 180 190 200
pF1KE2 HRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTI
.: :: ::: .:::: ::: .:::::..::::::::::. :.:.::.::::::::::::
XP_011 KRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQCEEWSFFHAYYYCFITLTTI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE2 GFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEH
::::::::: ::: .: ::::::.:::.::::::::::::::::.:::.:::.::::.
XP_011 GFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNSEDERRDAEE
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE2 RALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCLWYKSREK
:: :. :
XP_011 RASLAGNRNSMVIHIPEEPRPSRPRGTNCTFKRGVRGCWVSLPKPNTASGFLPSQVDLCC
160 170 180 190 200 210
>>NP_003731 (OMIM: 603493) potassium channel subfamily K (499 aa)
initn: 371 init1: 201 opt: 397 Z-score: 405.6 bits: 84.2 E(85289): 7.4e-16
Smith-Waterman score: 410; 32.5% identity (64.7% similar) in 252 aa overlap (18-256:15-259)
10 20 30 40 50
pF1KE2 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQE--LRARYNLSQGG
:: .:::.:..:: ::. : .. :. :. :.: :
NP_003 MVDRGPLLTSAIIFYLAIGAAIFEVLE-EPHWKEAKKNYYTQKLHLLKEFPCLGQEG
10 20 30 40 50
60 70 80 90 100 110
pF1KE2 YEELERVV-------LRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCM
... .:: . . ... .: . ... :: :::::::::..::.: .:..::.
NP_003 LDKILEVVSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCV
60 70 80 90 100 110
120 130 140 150 160
pF1KE2 FYALLGIPLTLVMFQSLGE----RINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSC
::.:.:.:: :. ...::. : . : ..: .:.:...:.:... . . .. ..
NP_003 FYGLFGVPLCLTWISALGKFFGGRAKRLGQFL---TKRGVSLRKAQITCTVIFIV--WGV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE2 ISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVY
. : : .: : :..... :: :::..::::::.:: . .: . . : : ..
NP_003 LVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSA-NYHALYRYFVELW
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE2 ILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASS
: ::. .. :.: : :. .. .::
NP_003 IYLGLAWLSLFVNWKVSMFVEVHKAIKKRRRRRKESFESSPHSRKALQVKGSTASKDVNI
240 250 260 270 280 290
394 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:39:53 2016 done: Tue Nov 8 17:39:54 2016
Total Scan time: 6.730 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]