Result of FASTA (ccds) for
pF1KE2646
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2646, 2249 aa
1>>>pF1KE2646 2249 - 2249 aa - 2249 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.2800+/-0.00131; mu= -17.2822+/- 0.079
mean_var=673.1075+/-138.138, 0's: 0 Z-trim(116.6): 128 B-trim: 0 in 0/53
Lambda= 0.049435
statistics sampled from 17060 (17184) to 17060 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.528), width: 16
Scan time: 9.650
The best scores are: opt bits E(32554)
CCDS55072.1 ARID1B gene_id:57492|Hs108|chr6 (2249) 15624 1131.1 0
CCDS5251.2 ARID1B gene_id:57492|Hs108|chr6 (2236) 12103 880.0 0
CCDS285.1 ARID1A gene_id:8289|Hs108|chr1 (2285) 3736 283.3 8.7e-75
CCDS44091.1 ARID1A gene_id:8289|Hs108|chr1 (2068) 3359 256.4 1e-66
>>CCDS55072.1 ARID1B gene_id:57492|Hs108|chr6 (2249 aa)
initn: 15624 init1: 15624 opt: 15624 Z-score: 6038.3 bits: 1131.1 E(32554): 0
Smith-Waterman score: 15624; 100.0% identity (100.0% similar) in 2249 aa overlap (1-2249:1-2249)
10 20 30 40 50 60
pF1KE2 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 TGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 QLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE2 GVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE2 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE2 SPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE2 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE2 GPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE2 SAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE2 QGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE2 ESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFM
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE2 EERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 EERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE2 LKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGS
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE2 NSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 NSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPY
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE2 QQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 QQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE2 LGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMY
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE2 GPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQT
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE2 HGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 HGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMM
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE2 VPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQ
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE2 RSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 RSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVL
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE2 KQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 KQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFL
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE2 ELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDD
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE2 DEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVV
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE2 DRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQE
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE2 GKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLE
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE2 DEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 DEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLIL
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE2 LHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 LHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAY
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE2 TESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 TESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLIL
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE2 ATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 ATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLI
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE2 SFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEG
2170 2180 2190 2200 2210 2220
2230 2240
pF1KE2 RLLDISISAVLNSLVASVICDVLFQIGQL
:::::::::::::::::::::::::::::
CCDS55 RLLDISISAVLNSLVASVICDVLFQIGQL
2230 2240
>>CCDS5251.2 ARID1B gene_id:57492|Hs108|chr6 (2236 aa)
initn: 11473 init1: 11473 opt: 12103 Z-score: 4681.2 bits: 880.0 E(32554): 0
Smith-Waterman score: 15489; 99.4% identity (99.4% similar) in 2249 aa overlap (1-2249:1-2236)
10 20 30 40 50 60
pF1KE2 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 MAHNAGAAAAAGTHSAKSGGSEAALKEGGSAAALSSSSSSSAAAAAASSSSSSGPGSAME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 TGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 TGLLPNHKLKTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 SGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 SGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 YSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 QLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 QLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 AQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 AQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHSQPQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQDSGDATWKETFWLMPPQYGQQ
::::::::::::::::::::::::::::::::::::::: ::::::::
CCDS52 QSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ-------------MPPQYGQQ
550 560 570 580
610 620 630 640 650 660
pF1KE2 GVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 GVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE2 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 KPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE2 SPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 SPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPA
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE2 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 LSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTY
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE2 GPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 GPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMP
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE2 SAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 SAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSR
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE2 QGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 QGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPG
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 ESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 ESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFM
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 EERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 EERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASS
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 LKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 LKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGS
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 NSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 NSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPY
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 QQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 QQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE2 LGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 LGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMY
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KE2 GPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 GPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQT
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480 1490 1500
pF1KE2 HGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 HGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMM
1430 1440 1450 1460 1470 1480
1510 1520 1530 1540 1550 1560
pF1KE2 VPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 VPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQ
1490 1500 1510 1520 1530 1540
1570 1580 1590 1600 1610 1620
pF1KE2 RSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 RSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVL
1550 1560 1570 1580 1590 1600
1630 1640 1650 1660 1670 1680
pF1KE2 KQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 KQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFL
1610 1620 1630 1640 1650 1660
1690 1700 1710 1720 1730 1740
pF1KE2 ELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 ELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDD
1670 1680 1690 1700 1710 1720
1750 1760 1770 1780 1790 1800
pF1KE2 DEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 DEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVV
1730 1740 1750 1760 1770 1780
1810 1820 1830 1840 1850 1860
pF1KE2 DRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 DRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKKEQE
1790 1800 1810 1820 1830 1840
1870 1880 1890 1900 1910 1920
pF1KE2 GKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 GKGDSEEQQEKSIIATIDDVLSARPGALPEDANPGPQTESSKFPFGIQQAKSHRNIKLLE
1850 1860 1870 1880 1890 1900
1930 1940 1950 1960 1970 1980
pF1KE2 DEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 DEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLIL
1910 1920 1930 1940 1950 1960
1990 2000 2010 2020 2030 2040
pF1KE2 LHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 LHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAY
1970 1980 1990 2000 2010 2020
2050 2060 2070 2080 2090 2100
pF1KE2 TESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 TESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLIL
2030 2040 2050 2060 2070 2080
2110 2120 2130 2140 2150 2160
pF1KE2 ATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 ATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLI
2090 2100 2110 2120 2130 2140
2170 2180 2190 2200 2210 2220
pF1KE2 SFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS52 SFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEG
2150 2160 2170 2180 2190 2200
2230 2240
pF1KE2 RLLDISISAVLNSLVASVICDVLFQIGQL
:::::::::::::::::::::::::::::
CCDS52 RLLDISISAVLNSLVASVICDVLFQIGQL
2210 2220 2230
>>CCDS285.1 ARID1A gene_id:8289|Hs108|chr1 (2285 aa)
initn: 5031 init1: 1919 opt: 3736 Z-score: 1456.1 bits: 283.3 E(32554): 8.7e-75
Smith-Waterman score: 7221; 52.3% identity (70.3% similar) in 2354 aa overlap (116-2248:25-2284)
90 100 110 120 130 140
pF1KE2 HHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGG
.. .:::... . . . . :..
CCDS28 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAA
10 20 30 40 50
150 160 170 180 190 200
pF1KE2 GAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGL
: . :: . :: : :. :.... : . : : : . . :. .:.:
CCDS28 GQESEGPAVGPPQPLG-KELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPAL
60 70 80 90 100 110
210 220 230 240 250
pF1KE2 GALGTQQPPVAVPGGGGGPA---AVPEFNNYYGSAAPASG-G-PGGR--------AGPCF
. . .:: ::::: . ..: . . :: : : : :: :. :
CCDS28 NN-NLTEPP---GGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVF
120 130 140 150 160
260 270 280 290 300 310
pF1KE2 -DQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHE-GYPNSQCNHYPGYSRPGAGGGG
.:::::::::.. ..:... .: : ::::. :.:: : : : : .:
CCDS28 HQQHGGQQSPGLAALQSGGG--GGLEPYAGPQQNSHDHGFPNHQYNSY--YPNRSAYPPP
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE2 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS
. . . .. :: :.:.:.:.:. ..:.:.... ::
CCDS28 APAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSS--------------------SS
230 240 250 260
380 390 400 410 420 430
pF1KE2 PRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMM
:: : : :::: ::::: : : :. :::::::::::::
CCDS28 FAQQRFGAM---GGGGP---------SAAGG-----GTPQ-PT-ATPTLNQLLTSPSSA-
270 280 290 300
440 450 460 470 480
pF1KE2 RSYGGSYP--EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP
:.: : :: .::. ::. .:. : : ..: .. .: :::.
CCDS28 RGYQG-YPGGDYSGG---------PQDGGAGKGPADMASQCWGA-------AAAAAAAAA
310 320 330 340
490 500 510 520 530
pF1KE2 AWAAAQQRSHPA-MSPGTPG----PTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQ----
: ..:::::: : ::::. : : : .:::: : ::: :: :.::.::
CCDS28 ASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYG-GTNPYSQQQGP
350 360 370 380 390 400
540 550 560 570 580
pF1KE2 ---PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQY----P---QQQDSGDATWKE
:::. ::: :: :::::. .:::. .::.:..: : :: :: . .
CCDS28 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQ
410 420 430 440 450 460
590 600 610 620
pF1KE2 TFWL-----MP----PQYGQQGVS-------GYCQQGQ---------QPYYSQQP-QPPH
: . : : :.:: : .: :: : :: ::::: ::::
CCDS28 TPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPH
470 480 490 500 510 520
630
pF1KE2 ------LP------------------PQAQ-----YLPSQ--------------------
: :::: :.:
CCDS28 QQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS
530 540 550 560 570 580
640 650 660 670 680
pF1KE2 -----SQQRYQPQQDMSQEGYGTR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSID
::::. : :..::...:.. : : .. .: ..::.:: : :::::::::::::
CCDS28 QQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID
590 600 610 620 630 640
690 700 710 720 730 740
pF1KE2 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGS
::: :::..:: .::.:: .::::.::::::::::::.:::: .: : :::::::::..
CCDS28 DLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASV
650 660 670 680 690 700
750 760 770 780 790 800
pF1KE2 NQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYG
::::::.:::..::.::::.::..::.: ::...:: . :.::.: :::::: ::.
CCDS28 AQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYS
710 720 730 740 750 760
810 820 830 840 850 860
pF1KE2 PQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS
: : ..::. :::.:.:..:.:: :: :.:::: .::::::.: : : :...:.:.
CCDS28 SPQPGSALSPRQPSGGQIHTGMGSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNAN
770 780 790 800 810 820
870 880 890 900 910 920
pF1KE2 YSGPGPGMGIS---ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGM
: . : . ::. :..::::: : :..: ::: :.: :::. ::..: :
CCDS28 YPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-----
830 840 850 860 870
930 940 950 960 970 980
pF1KE2 SQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPM
: : :: :: .:::.::.:.: :..:::: :.: ..:.:::.:.:... ::.: .
CCDS28 --QVGSGMCPPPGGMNRKTQETAVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGI
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE2 NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESK
:. ....: :.:::::. .:.:.::. .. .::. :. :: : ..: .:::. :::
CCDS28 NSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESK
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE2 SKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRL
::::::::::.:::::.::::.:::::.::::::.: ::.. ...:::::.:::::.::
CCDS28 SKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRL
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE2 YVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPP
:: :::::::.::::::::::::::::::::::::::::::::: :.::::::::::.::
CCDS28 YVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPP
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE2 PEVFSTGDTKK-QPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQ
:..:...:.:: :::.::::::.:::.::::::::: :.:::: :::::::::::::.:
CCDS28 PDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHSQ
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE2 MTPMQG-GRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDP
. :. : .::......: :.: :::.: :::::::: :: .:. :.:::: :::::::
CCDS28 IPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDP
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330
pF1KE2 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDR----
.:.:::.::: .:::..:: ::..: : :... . ...:..:: ::..:::. :::
CCDS28 YGSMRKAPGS-DPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTE
1240 1250 1260 1270 1280 1290
1340 1350
pF1KE2 -------------------------------------------RHEPYGQQYPGQGPPSG
::. ::.:. :: :::
CCDS28 PGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTPSG
1300 1310 1320 1330 1340 1350
1360 1370 1380 1390
pF1KE2 QPPYGGHQPGLYPQQP-NYKRHMDGMYGPPAKRHEGDMYNMQYS----------------
.: . ..: .: :: :::: ::: ::::::::::.::.. ::
CCDS28 SP-FPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQP
1360 1370 1380 1390 1400 1410
1400 1410 1420 1430
pF1KE2 -----------SQQQEMYNQYGGSY-----SGPDRRPI---QGQYPYPYSRERMQGP-GQ
: ::..:::::..: .. .::: :.:.:. ..:.:...: :
CCDS28 QPASQQQAAQPSPQQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGT
1420 1430 1440 1450 1460 1470
1440 1450 1460 1470 1480 1490
pF1KE2 IQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTD
...::::::::.:.:. . : .:: .:::: : : :::. :. :.: : :.::::
CCDS28 NAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTD
1480 1490 1500 1510 1520 1530
1500 1510 1520 1530 1540 1550
pF1KE2 DMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPA
.:. ::: :::..:::: . ::: .. :: . :.:::: .:: :::. ::: .. :::
CCDS28 EMLHTDQRANHEGSWPSH-GTRQPPYGPSAPVPPMTRPPPSNYQPPPSMQNHIPQVSSPA
1540 1550 1560 1570 1580
1560 1570 1580 1590 1600 1610
pF1KE2 SFQRSLENRMSPSKSPFLPS-MKMQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEAS
. : .::: :::::::: : :::::. : ::.:... : ::: :::.::::::::::.
CCDS28 PLPRPMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEAT
1590 1600 1610 1620 1630 1640
1620 1630 1640 1650 1660 1670
pF1KE2 QPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQL
::::::::..: ::: :::::::::::::::::::::::::::::::::... :::::::
CCDS28 QPVLKQRRRLTMKDIGTPEAWRVMMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQL
1650 1660 1670 1680 1690 1700
1680 1690 1700 1710 1720 1730
pF1KE2 SGFLELLVEYFRKCLIDIFGILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAE
:.:::::::::.:::.::::: :::::::.:..: . .: . .: : : :::. :
CCDS28 PGLLELLVEYFRRCLIEIFGILKEYEVGDPGQRTL-LDPGRFSKVSSPAPMEGGEEEE-E
1710 1720 1730 1740 1750 1760
1740 1750 1760 1770 1780 1790
pF1KE2 CIDDDEEDEEDEEEDSEKTESDEKSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNN
. :.::.:: .:.::. ::... : :. . . : :::::::.:::.::.
CCDS28 LLGPKLEEEEEEEV----VENDEE--IAFSGKDKPASENSEEKLISKFDKLPVKIVQKND
1770 1780 1790 1800 1810 1820
1800 1810 1820 1830 1840 1850
pF1KE2 LFVVDRSDKLGRVQEFNSGLLHWQLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRK
:::: ::::::::::.::::::..:::::::::::::::: :. : : : : : ::
CCDS28 PFVVDCSDKLGRVQEFDSGLLHWRIGGGDTTEHIQTHFESKTELLPSR-PHAPCPPAPRK
1830 1840 1850 1860 1870 1880
1860 1870 1880 1890 1900
pF1KE2 K--EQEGKGDSEEQQ--------EKSIIATIDDVLSARPGALPEDANPGPQT--ESSKFP
. :: . .:. :: : ::.::.::.: ..: ::. . .. ::::::
CCDS28 HVTTAEGTPGTTDQEGPPPDGPPEKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFP
1890 1900 1910 1920 1930 1940
1910 1920 1930 1940 1950 1960
pF1KE2 FGIQQAKSHRNIKLLEDEPRSRDETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAE
:::. :.::::::.:::::.:.:::::::. :::::::::.:::: .:::::::::: :
CCDS28 FGISPAQSHRNIKILEDEPHSKDETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFE
1950 1960 1970 1980 1990 2000
1970 1980 1990 2000 2010 2020
pF1KE2 MSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNT
:::::::.:::::::::::.:::::.:: ::::::..:.::.:.: ::::::::.::.::
CCDS28 MSKHPGLLLILGKLILLHHKHPERKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENT
2010 2020 2030 2040 2050 2060
2030 2040 2050 2060 2070 2080
pF1KE2 LVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLE
:::::::::::::: : ::::::.::::::: ::::::::::: :.:::.::::::::::
CCDS28 LVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLE
2070 2080 2090 2100 2110 2120
2090 2100 2110 2120 2130 2140
pF1KE2 TLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDAL
:: :::::::::::::::::::: ::.:.:.::...::::::::::...::.::::::.:
CCDS28 TLSKLSIQDNNVDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSL
2130 2140 2150 2160 2170 2180
2150 2160 2170 2180 2190 2200
pF1KE2 AARAIAVQKGSIGNLISFLEDGVTMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLA
:::::::::::::::..::::... .:.:::: .:.::: ::.:: ::::: :::.::::
CCDS28 AARAIAVQKGSIGNLLGFLEDSLAATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLA
2190 2200 2210 2220 2230 2240
2210 2220 2230 2240
pF1KE2 MARVDENRSEFLLHEGRLLDISISAVLNSLVASVICDVLFQIGQL
.:.::::.::: :.:.::::::.: ..::::..::::::: :::
CCDS28 LAKVDENHSEFTLYESRLLDISVSPLMNSLVSQVICDVLFLIGQS
2250 2260 2270 2280
>>CCDS44091.1 ARID1A gene_id:8289|Hs108|chr1 (2068 aa)
initn: 4258 init1: 1919 opt: 3359 Z-score: 1311.4 bits: 256.4 E(32554): 1e-66
Smith-Waterman score: 6479; 50.9% identity (68.3% similar) in 2271 aa overlap (116-2248:25-2067)
90 100 110 120 130 140
pF1KE2 HHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGG
.. .:::... . . . . :..
CCDS44 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAA
10 20 30 40 50
150 160 170 180 190 200
pF1KE2 GAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGL
: . :: . :: : :. :.... : . : : : . . :. .:.:
CCDS44 GQESEGPAVGPPQPLG-KELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPAL
60 70 80 90 100 110
210 220 230 240 250
pF1KE2 GALGTQQPPVAVPGGGGGPA---AVPEFNNYYGSAAPASG-G-PGGR--------AGPCF
. . .:: ::::: . ..: . . :: : : : :: :. :
CCDS44 NN-NLTEPP---GGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVF
120 130 140 150 160
260 270 280 290 300 310
pF1KE2 -DQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHE-GYPNSQCNHYPGYSRPGAGGGG
.:::::::::.. ..:... .: : ::::. :.:: : : : : .:
CCDS44 HQQHGGQQSPGLAALQSGGG--GGLEPYAGPQQNSHDHGFPNHQYNSY--YPNRSAYPPP
170 180 190 200 210 220
320 330 340 350 360 370
pF1KE2 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS
. . . .. :: :.:.:.:.:. ..:.:.... ::
CCDS44 APAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSS--------------------SS
230 240 250 260
380 390 400 410 420 430
pF1KE2 PRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMM
:: : : :::: ::::: : : :. :::::::::::::
CCDS44 FAQQRFGAM---GGGGP---------SAAGG-----GTPQ-PT-ATPTLNQLLTSPSSA-
270 280 290 300
440 450 460 470 480
pF1KE2 RSYGGSYP--EYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASP
:.: : :: .::. ::. .:. : : ..: .. .: :::.
CCDS44 RGYQG-YPGGDYSGG---------PQDGGAGKGPADMASQCWGA-------AAAAAAAAA
310 320 330 340
490 500 510 520 530
pF1KE2 AWAAAQQRSHPA-MSPGTPG----PTMGRSQ-GSPMDPMVMKRPQLYGMGSNPHSQ----
: ..:::::: : ::::. : : : .:::: : ::: :: :.::.::
CCDS44 ASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYG-GTNPYSQQQGP
350 360 370 380 390 400
540 550 560 570 580
pF1KE2 ---PQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQY----P---QQQDSGDATWKE
:::. ::: :: :::::. .:::. .::.:..: : :: :: . .
CCDS44 PSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQ
410 420 430 440 450 460
590 600 610 620
pF1KE2 TFWL-----MP----PQYGQQGVS-------GYCQQGQ---------QPYYSQQP-QPPH
: . : : :.:: : .: :: : :: ::::: ::::
CCDS44 TPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPH
470 480 490 500 510 520
630
pF1KE2 ------LP------------------PQAQ-----YLPSQ--------------------
: :::: :.:
CCDS44 QQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQS
530 540 550 560 570 580
640 650 660 670 680
pF1KE2 -----SQQRYQPQQDMSQEGYGTR--SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSID
::::. : :..::...:.. : : .. .: ..::.:: : :::::::::::::
CCDS44 QQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSID
590 600 610 620 630 640
690 700 710 720 730 740
pF1KE2 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGS
::: :::..:: .::.:: .::::.::::::::::::.:::: .: : :::::::::..
CCDS44 DLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRG-PSPSPVGSPASV
650 660 670 680 690 700
750 760 770 780 790 800
pF1KE2 NQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYG
::::::.:::..::.::::.::..::.: ::...:: . :.::.: :::::: ::.
CCDS44 AQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYM---QRNPQMPQYS
710 720 730 740 750 760
810 820 830 840 850 860
pF1KE2 PQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS
: : ..::. :::.:.:..:.:: :: :.:::: .::::::.: : : :...:.:.
CCDS44 SPQPGSALSPRQPSGGQIHTGMGSYQQ-NSMGSYGPQGGQYGPQGGYPRQPNYNALPNAN
770 780 790 800 810 820
870 880 890 900 910 920
pF1KE2 YSGPGPGMGIS---ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGM
: . : . ::. :..::::: : :..: ::: :.: :::. ::..: :
CCDS44 YPSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPP-----
830 840 850 860 870
930 940 950 960 970 980
pF1KE2 SQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPM
: : :: :: .:::.::.:.: :..:::: :.: ..:.:::.:.:... ::.: .
CCDS44 --QVGSGMCPPPGGMNRKTQETAVA-MHVAANSIQNRPPGYPNMNQGGMMGTGPPYGQGI
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE2 NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESK
:. ....: :.:::::. .:.:.::. .. .::. :. :: : ..: .:::. :::
CCDS44 NSMAGMINPQGPPYSMGGTMANNSAGMAASPEMMGLGDVKLTPATKMNNKADGTPKTESK
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE2 SKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRL
::::::::::.:::::.::::.:::::.::::::.: ::.. ...:::::.:::::.::
CCDS44 SKKSSSSTTTNEKITKLYELGGEPERKMWVDRYLAFTEEKAMGMTNLPAVGRKPLDLYRL
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE2 YVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPP
:: :::::::.::::::::::::::::::::::::::::::::: :.::::::::::.::
CCDS44 YVSVKEIGGLTQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQCLYAFECKIERGEDPP
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE2 PEVFSTGDTKK-QPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQ
:..:...:.:: :::.::::::.:::.::::::::: :.:::: :::::::::::::.:
CCDS44 PDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQST-SSSMAE-GGDLKPPTPASTPHSQ
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE2 MTPMQG-GRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDP
. :. : .::......: :.: :::.: :::::::: :: .:. :.:::: :::::::
CCDS44 IPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKDP
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE2 FGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDR-RHE
.:.:::.::: .:::..:: ::..: : :... . ...:..:: ::..:::. ::: : :
CCDS44 YGSMRKAPGS-DPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTE
1240 1250 1260 1270 1280 1290
1350 1360 1370 1380 1390 1400
pF1KE2 PYGQQYPGQGPPSGQPPYGGHQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQ
:: :: :. :. ::.:.:..:. .:::.: . : : ..::
CCDS44 ------PGIGPE-GNMSTGAPQPNLMPSNPD-----SGMYSP-------SRYPPQQQQQQ
1300 1310 1320 1330
1410 1420 1430 1440 1450 1460
pF1KE2 QEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGP
:. ...::...: :.: : :.:
CCDS44 QQRHDSYGNQFS---------------------------TQGTP----------SGS---
1340 1350
1470 1480 1490 1500 1510 1520
pF1KE2 QQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQ
:.: : :. : :.:
CCDS44 -----------PFPSQ---------QTTMY---------------------------QQQ
1360
1530 1540 1550 1560 1570
pF1KE2 PYMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPS-MK
.:: : :. :: .::: :::::::: : ::
CCDS44 QQVSSPA---PLPRP---------------------------MENRTSPSKSPFLHSGMK
1370 1380 1390
1580 1590 1600 1610 1620 1630
pF1KE2 MQKVMPTVPTSQVTGPPPQPPPIRREITFPPGSVEASQPVLKQRRKITSKDIVTPEAWRV
:::. : ::.:... : ::: :::.::::::::::.::::::::..: ::: :::::::
CCDS44 MQKAGPPVPASHIAPAPVQPPMIRRDITFPPGSVEATQPVLKQRRRLTMKDIGTPEAWRV
1400 1410 1420 1430 1440 1450
1640 1650 1660 1670 1680 1690
pF1KE2 MMSLKSGLLAESTWALDTINILLYDDSTVATFNLSQLSGFLELLVEYFRKCLIDIFGILM
::::::::::::::::::::::::::... ::::::: :.:::::::::.:::.:::::
CCDS44 MMSLKSGLLAESTWALDTINILLYDDNSIMTFNLSQLPGLLELLVEYFRRCLIEIFGILK
1460 1470 1480 1490 1500 1510
1700 1710 1720 1730 1740 1750
pF1KE2 EYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEEEDSEKTESDE
:::::::.:..: . .: . .: : : :::. : . :.::.:: .:.::
CCDS44 EYEVGDPGQRTL-LDPGRFSKVSSPAPMEGGEEEE-ELLGPKLEEEEEEEV----VENDE
1520 1530 1540 1550 1560
1760 1770 1780 1790 1800 1810
pF1KE2 KSSIALTAPDAAADPKEKPKQASKFDKLPIKIVKKNNLFVVDRSDKLGRVQEFNSGLLHW
. ::... : :. . . : :::::::.:::.::. :::: ::::::::::.::::::
CCDS44 E--IAFSGKDKPASENSEEKLISKFDKLPVKIVQKNDPFVVDCSDKLGRVQEFDSGLLHW
1570 1580 1590 1600 1610 1620
1820 1830 1840 1850 1860
pF1KE2 QLGGGDTTEHIQTHFESKMEIPPRRRPPPPLSSAGRKK--EQEGKGDSEEQQ--------
..:::::::::::::::: :. : : : : : ::. :: . .:.
CCDS44 RIGGGDTTEHIQTHFESKTELLPSR-PHAPCPPAPRKHVTTAEGTPGTTDQEGPPPDGPP
1630 1640 1650 1660 1670 1680
1870 1880 1890 1900 1910 1920
pF1KE2 EKSIIATIDDVLSARPGALPEDANPGPQT--ESSKFPFGIQQAKSHRNIKLLEDEPRSRD
:: : ::.::.::.: ..: ::. . .. :::::::::. :.::::::.:::::.:.:
CCDS44 EKRITATMDDMLSTRSSTLTEDGAKSSEAIKESSKFPFGISPAQSHRNIKILEDEPHSKD
1690 1700 1710 1720 1730 1740
1930 1940 1950 1960 1970 1980
pF1KE2 ETPLCTIAHWQDSLAKRCICVSNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPE
::::::. :::::::::.:::: .:::::::::: ::::::::.:::::::::::.:::
CCDS44 ETPLCTLLDWQDSLAKRCVCVSNTIRSLSFVPGNDFEMSKHPGLLLILGKLILLHHKHPE
1750 1760 1770 1780 1790 1800
1990 2000 2010 2020 2030 2040
pF1KE2 RKRAPQTYEKEEDEDKGVACSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLP
::.:: ::::::..:.::.:.: ::::::::.::.:::::::::::::::: : ::::::
CCDS44 RKQAPLTYEKEEEQDQGVSCNKVEWWWDCLEMLRENTLVTLANISGQLDLSPYPESICLP
1810 1820 1830 1840 1850 1860
2050 2060 2070 2080 2090 2100
pF1KE2 ILDGLLHWMVCPSAEAQDPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSR
.::::::: ::::::::::: :.:::.:::::::::::: ::::::::::::::::::::
CCDS44 VLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDNNVDLILATPPFSR
1870 1880 1890 1900 1910 1920
2110 2120 2130 2140 2150 2160
pF1KE2 QEKFYATLVRYVGDRKNPVCREMSMALLSNLAQGDALAARAIAVQKGSIGNLISFLEDGV
::.:.:.::...::::::::::...::.::::::.::::::::::::::::..::::..
CCDS44 LEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSL
1930 1940 1950 1960 1970 1980
2170 2180 2190 2200 2210 2220
pF1KE2 TMAQYQQSQHNLMHMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISI
. .:.:::: .:.::: ::.:: ::::: :::.::::.:.::::.::: :.:.::::::.
CCDS44 AATQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTLYESRLLDISV
1990 2000 2010 2020 2030 2040
2230 2240
pF1KE2 SAVLNSLVASVICDVLFQIGQL
: ..::::..::::::: :::
CCDS44 SPLMNSLVSQVICDVLFLIGQS
2050 2060
2249 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 11 16:56:29 2016 done: Fri Nov 11 16:56:31 2016
Total Scan time: 9.650 Total Display time: 1.030
Function used was FASTA [36.3.4 Apr, 2011]