Result of FASTA (ccds) for
pF1KE2649
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2649, 191 aa
1>>>pF1KE2649 191 - 191 aa - 191 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1457+/-0.000713; mu= 14.2952+/- 0.043
mean_var=69.2163+/-14.023, 0's: 0 Z-trim(110.2): 171 B-trim: 360 in 1/50
Lambda= 0.154159
statistics sampled from 11279 (11465) to 11279 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.352), width: 16
Scan time: 2.070
The best scores are: opt bits E(32554)
CCDS221.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 1271 291.0 3e-79
CCDS222.1 CDC42 gene_id:998|Hs108|chr1 ( 191) 1224 280.5 4.2e-76
CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 ( 192) 945 218.5 2e-57
CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 ( 192) 929 214.9 2.4e-56
CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 ( 192) 916 212.0 1.8e-55
CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 ( 205) 879 203.8 5.6e-53
CCDS7748.1 RHOG gene_id:391|Hs108|chr11 ( 191) 837 194.5 3.4e-50
CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 ( 214) 833 193.6 7e-50
CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 ( 258) 769 179.4 1.6e-45
CCDS2795.1 RHOA gene_id:387|Hs108|chr3 ( 193) 705 165.1 2.4e-41
CCDS10068.1 RHOV gene_id:171177|Hs108|chr15 ( 236) 697 163.4 9.6e-41
CCDS854.1 RHOC gene_id:389|Hs108|chr1 ( 193) 690 161.8 2.4e-40
CCDS1699.1 RHOB gene_id:388|Hs108|chr2 ( 196) 661 155.3 2.1e-38
CCDS8155.1 RHOD gene_id:29984|Hs108|chr11 ( 210) 596 140.9 5.1e-34
CCDS9222.1 RHOF gene_id:54509|Hs108|chr12 ( 211) 581 137.6 5.1e-33
CCDS82775.1 RHOA gene_id:387|Hs108|chr3 ( 187) 575 136.2 1.2e-32
CCDS5349.1 RAC1 gene_id:5879|Hs108|chr7 ( 211) 527 125.5 2.1e-29
CCDS3458.1 RHOH gene_id:399|Hs108|chr4 ( 191) 521 124.2 4.9e-29
CCDS2190.1 RND3 gene_id:390|Hs108|chr2 ( 244) 508 121.4 4.5e-28
CCDS11452.1 RND2 gene_id:8153|Hs108|chr17 ( 227) 475 114.0 6.8e-26
CCDS8771.1 RND1 gene_id:27289|Hs108|chr12 ( 232) 436 105.3 2.8e-23
CCDS6034.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 727) 326 81.2 1.6e-15
CCDS55211.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 734) 326 81.2 1.6e-15
CCDS55210.1 RHOBTB2 gene_id:23221|Hs108|chr8 ( 749) 326 81.2 1.7e-15
CCDS7261.1 RHOBTB1 gene_id:9886|Hs108|chr10 ( 696) 325 81.0 1.8e-15
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 279 70.4 7.8e-13
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 271 68.6 3e-12
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 271 68.6 3.2e-12
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 262 66.6 1.1e-11
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 258 65.7 2e-11
CCDS62431.1 RIT2 gene_id:6014|Hs108|chr18 ( 153) 256 65.2 2.3e-11
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 257 65.5 2.3e-11
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 256 65.3 2.9e-11
CCDS11921.1 RIT2 gene_id:6014|Hs108|chr18 ( 217) 256 65.3 3e-11
CCDS41846.1 RAB35 gene_id:11021|Hs108|chr12 ( 201) 250 63.9 7.2e-11
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 249 63.6 7.3e-11
>>CCDS221.1 CDC42 gene_id:998|Hs108|chr1 (191 aa)
initn: 1271 init1: 1271 opt: 1271 Z-score: 1536.2 bits: 291.0 E(32554): 3e-79
Smith-Waterman score: 1271; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
130 140 150 160 170 180
190
pF1KE2 EPKKSRRCVLL
:::::::::::
CCDS22 EPKKSRRCVLL
190
>>CCDS222.1 CDC42 gene_id:998|Hs108|chr1 (191 aa)
initn: 1271 init1: 1224 opt: 1224 Z-score: 1479.7 bits: 280.5 E(32554): 4.2e-76
Smith-Waterman score: 1224; 95.3% identity (98.4% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS22 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
CCDS22 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPP
130 140 150 160 170 180
190
pF1KE2 EPKKSRRCVLL
: . .:.: ..
CCDS22 ETQPKRKCCIF
190
>>CCDS5348.1 RAC1 gene_id:5879|Hs108|chr7 (192 aa)
initn: 938 init1: 938 opt: 945 Z-score: 1144.3 bits: 218.5 E(32554): 2e-57
Smith-Waterman score: 945; 70.8% identity (89.1% similar) in 192 aa overlap (1-191:1-192)
10 20 30 40 50 60
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
::.::::::::::::::::::::::: ::.::.:::::::...::. :.: .:::.::::
CCDS53 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
:::::::::::::::::::.:::.:::.:::::. :: ::. ::::.::..::::..:::
CCDS53 QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
:: .::::: ..: ::: . .:... ::::.:::::::.:::.:::::: :.: ::
CCDS53 DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP
130 140 150 160 170 180
190
pF1KE2 EPKK-SRRCVLL
:: .:.:.::
CCDS53 PVKKRKRKCLLL
190
>>CCDS11798.1 RAC3 gene_id:5881|Hs108|chr17 (192 aa)
initn: 948 init1: 920 opt: 929 Z-score: 1125.1 bits: 214.9 E(32554): 2.4e-56
Smith-Waterman score: 929; 69.3% identity (88.5% similar) in 192 aa overlap (1-191:1-192)
10 20 30 40 50 60
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
::.::::::::::::::::::::::: ::.::.:::::::...::. :.: .:::.::::
CCDS11 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
:::::::::::::::::::.:::.:::.:::::. :: ::. ::::.::.:::::..:::
CCDS11 QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
:: .:::.: .: ::: . .::.. .:::.:::::::.:::.:::::: :.: ::
CCDS11 DDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPP
130 140 150 160 170 180
190
pF1KE2 EPKK-SRRCVLL
:: ...:...
CCDS11 PVKKPGKKCTVF
190
>>CCDS13945.1 RAC2 gene_id:5880|Hs108|chr22 (192 aa)
initn: 939 init1: 904 opt: 916 Z-score: 1109.4 bits: 212.0 E(32554): 1.8e-55
Smith-Waterman score: 916; 68.8% identity (88.0% similar) in 192 aa overlap (1-191:1-192)
10 20 30 40 50 60
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
::.::::::::::::::::::::::: ::.::.:::::::...::. ..: .:::.::::
CCDS13 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
:::::::::::::::::::.:::.:::.:.:::. :: ::. ::::.::..::::..:::
CCDS13 QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR
70 80 90 100 110 120
130 140 150 160 170
pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEP-
:: .::::: ..: ::: . ::... .:::.:::::::.:::.:::::: :.: :
CCDS13 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ
130 140 150 160 170 180
180 190
pF1KE2 PEPKKSRRCVLL
: ...: : ::
CCDS13 PTRQQKRACSLL
190
>>CCDS33191.1 RHOQ gene_id:23433|Hs108|chr2 (205 aa)
initn: 891 init1: 871 opt: 879 Z-score: 1064.6 bits: 203.8 E(32554): 5.6e-53
Smith-Waterman score: 879; 67.4% identity (86.3% similar) in 190 aa overlap (4-189:10-199)
10 20 30 40 50
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLG
.::::::::::::::::.::... :: ::::::::.:::.: .::. : ::
CCDS33 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 LFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVG
:.:::::::::::::::::.:::::.:::::.:.::.::::.::::. .. :..::::.:
CCDS33 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 TQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAIL
:::::::::.:. .: :.::: : ..:::... : :::::::::::::.::::::.
CCDS33 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII
130 140 150 160 170 180
180 190
pF1KE2 AALEPPEPK-KSR---RCVLL
: : : . :.: ::.
CCDS33 AILTPKKHTVKKRIGSRCINCCLIT
190 200
>>CCDS7748.1 RHOG gene_id:391|Hs108|chr11 (191 aa)
initn: 837 init1: 837 opt: 837 Z-score: 1014.5 bits: 194.5 E(32554): 3.4e-50
Smith-Waterman score: 837; 60.7% identity (85.3% similar) in 191 aa overlap (1-191:1-191)
10 20 30 40 50 60
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG
::.:::::::::::::::::: :::: ::.::.:::::::.. . :. .:.:.::::
CCDS77 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR
::.::::: ::::::.::..:::..:: :.:::..:: ::. :::: .:.:::::. :::
CCDS77 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP
.:.:...: .. : ::::. .. ::....::.:.::::: : :.:.:: ::. :.:.:
CCDS77 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT
130 140 150 160 170 180
190
pF1KE2 EPKKSRRCVLL
:..: :.::
CCDS77 PIKRGRSCILL
190
>>CCDS9757.1 RHOJ gene_id:57381|Hs108|chr14 (214 aa)
initn: 824 init1: 824 opt: 833 Z-score: 1009.0 bits: 193.6 E(32554): 7e-50
Smith-Waterman score: 833; 64.2% identity (86.1% similar) in 187 aa overlap (2-188:20-204)
10 20 30 40
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAV
. .::::::::::::::::.::... :: ::::::::.:::
CCDS97 MNCKEGTDSSCGCRGNDEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE2 TVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEIT
:: .::. . :::.::::::::..:::::::.:::::.:::::.:.:..::.:.::::.
CCDS97 TVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE2 HHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQ
:..:..:.::::::::::.:. .: :.::.: : . :::. . : :.:::::::
CCDS97 DCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQ
130 140 150 160 170 180
170 180 190
pF1KE2 KGLKNVFDEAILAALEPPEPKKSRRCVLL
:::: :::::::. ..: ::..::
CCDS97 KGLKAVFDEAILTIFHPK--KKKKRCSEGHSCCSII
190 200 210
>>CCDS1575.1 RHOU gene_id:58480|Hs108|chr1 (258 aa)
initn: 792 init1: 753 opt: 769 Z-score: 930.9 bits: 179.4 E(32554): 1.6e-45
Smith-Waterman score: 769; 60.1% identity (85.1% similar) in 188 aa overlap (4-186:50-236)
10 20 30
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYV
.:::.::::::::: :..::::: .:.::.
CCDS15 PPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYI
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE2 PTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENV
::.:::....: . :.: : : :::::...:.:::: : .::.::.::::::::::.::
CCDS15 PTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNV
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE2 KEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKL-ARDLKAV
.::::::: ::::.:..::::: :::.: ... .: : :.::. :: : :: :...::.
CCDS15 SEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPV-PEEAAKLCAEEIKAA
140 150 160 170 180 190
160 170 180 190
pF1KE2 KYVECSALTQKGLKNVFDEAILAALE----PPEPKKSRRCVLL
.:.::::::::.::.::: ::.:... .::::.
CCDS15 SYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCFV
200 210 220 230 240 250
>>CCDS2795.1 RHOA gene_id:387|Hs108|chr3 (193 aa)
initn: 711 init1: 692 opt: 705 Z-score: 855.8 bits: 165.1 E(32554): 2.4e-41
Smith-Waterman score: 705; 53.5% identity (79.1% similar) in 187 aa overlap (5-191:7-193)
10 20 30 40 50
pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDT
: :.::::: ::::::: .. ..:: ::::::.::.. . . :. :.:.::
CCDS27 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE2 AGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQID
:::::::::::::::.:::.:.:::. ::.:.::. :::.::. : ::..:..:::.. :
CCDS27 AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE2 LRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALE
::.: : ..::: ::.:. :: .. .: . : :.:::: :. :...::. : :::.
CCDS27 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
130 140 150 160 170 180
180 190
pF1KE2 PPEPKKSRRCVLL
. ::. :..:
CCDS27 ARRGKKKSGCLVL
190
191 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 11 16:57:32 2016 done: Fri Nov 11 16:57:32 2016
Total Scan time: 2.070 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]