FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KE2649, 191 aa 1>>>pF1KE2649 191 - 191 aa - 191 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.5147+/-0.000335; mu= 18.2179+/- 0.021 mean_var=73.7038+/-15.386, 0's: 0 Z-trim(117.2): 374 B-trim: 1597 in 3/50 Lambda= 0.149393 statistics sampled from 28550 (28985) to 28550 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.34), width: 16 Scan time: 6.150 The best scores are: opt bits E(85289) NP_001034891 (OMIM: 116952,616737) cell division c ( 191) 1271 282.4 2.9e-76 NP_001782 (OMIM: 116952,616737) cell division cont ( 191) 1271 282.4 2.9e-76 NP_426359 (OMIM: 116952,616737) cell division cont ( 191) 1224 272.3 3.3e-73 NP_008839 (OMIM: 602048) ras-related C3 botulinum ( 192) 945 212.2 4.2e-55 NP_005043 (OMIM: 602050) ras-related C3 botulinum ( 192) 929 208.7 4.6e-54 NP_002863 (OMIM: 602049,608203) ras-related C3 bot ( 192) 916 205.9 3.2e-53 NP_036381 (OMIM: 605857) rho-related GTP-binding p ( 205) 879 198.0 8.4e-51 XP_005252973 (OMIM: 179505) PREDICTED: rho-related ( 191) 837 188.9 4.2e-48 XP_016873208 (OMIM: 179505) PREDICTED: rho-related ( 191) 837 188.9 4.2e-48 NP_001656 (OMIM: 179505) rho-related GTP-binding p ( 191) 837 188.9 4.2e-48 NP_065714 (OMIM: 607653) rho-related GTP-binding p ( 214) 833 188.1 8.3e-48 NP_067028 (OMIM: 606366) rho-related GTP-binding p ( 258) 769 174.4 1.3e-43 NP_001303236 (OMIM: 602050) ras-related C3 botulin ( 170) 764 173.1 2.1e-43 XP_006724349 (OMIM: 602049,608203) PREDICTED: ras- ( 161) 754 170.9 9.2e-43 XP_011531028 (OMIM: 605857) PREDICTED: rho-related ( 192) 744 168.9 4.6e-42 XP_016859205 (OMIM: 605857) PREDICTED: rho-related ( 172) 733 166.4 2.2e-41 NP_001655 (OMIM: 165390) transforming protein RhoA ( 193) 705 160.5 1.6e-39 NP_001300870 (OMIM: 165390) transforming protein R ( 193) 705 160.5 1.6e-39 NP_786886 (OMIM: 165380) rho-related GTP-binding p ( 193) 690 157.2 1.5e-38 NP_001036144 (OMIM: 165380) rho-related GTP-bindin ( 193) 690 157.2 1.5e-38 NP_001036143 (OMIM: 165380) rho-related GTP-bindin ( 193) 690 157.2 1.5e-38 XP_006720277 (OMIM: 607653) PREDICTED: rho-related ( 176) 687 156.5 2.2e-38 NP_004031 (OMIM: 165370) rho-related GTP-binding p ( 196) 661 151.0 1.1e-36 NP_055393 (OMIM: 605781) rho-related GTP-binding p ( 210) 596 137.0 2e-32 XP_011531030 (OMIM: 605857) PREDICTED: rho-related ( 157) 582 133.9 1.3e-31 NP_001300872 (OMIM: 165390) transforming protein R ( 187) 575 132.4 4.2e-31 NP_061485 (OMIM: 602048) ras-related C3 botulinum ( 211) 527 122.1 5.9e-28 XP_016863678 (OMIM: 602037) PREDICTED: rho-related ( 191) 521 120.8 1.3e-27 XP_016863677 (OMIM: 602037) PREDICTED: rho-related ( 191) 521 120.8 1.3e-27 XP_011511994 (OMIM: 602037) PREDICTED: rho-related ( 191) 521 120.8 1.3e-27 NP_001265288 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265293 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265291 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265298 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265297 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265290 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265294 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_004301 (OMIM: 602037) rho-related GTP-binding p ( 191) 521 120.8 1.3e-27 NP_001265292 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265289 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265296 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001265295 (OMIM: 602037) rho-related GTP-bindin ( 191) 521 120.8 1.3e-27 NP_001241667 (OMIM: 602924) rho-related GTP-bindin ( 244) 508 118.1 1.1e-26 NP_005159 (OMIM: 602924) rho-related GTP-binding p ( 244) 508 118.1 1.1e-26 NP_001300873 (OMIM: 165390) transforming protein R ( 173) 479 111.7 6.7e-25 NP_005431 (OMIM: 601555) rho-related GTP-binding p ( 227) 475 111.0 1.5e-24 XP_011523618 (OMIM: 601555) PREDICTED: rho-related ( 234) 475 111.0 1.5e-24 NP_055285 (OMIM: 609038) rho-related GTP-binding p ( 232) 436 102.6 5e-22 XP_011523619 (OMIM: 601555) PREDICTED: rho-related ( 206) 399 94.5 1.2e-19 NP_001300874 (OMIM: 165390) transforming protein R ( 112) 369 87.8 6.8e-18 >>NP_001034891 (OMIM: 116952,616737) cell division contr (191 aa) initn: 1271 init1: 1271 opt: 1271 Z-score: 1490.0 bits: 282.4 E(85289): 2.9e-76 Smith-Waterman score: 1271; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 130 140 150 160 170 180 190 pF1KE2 EPKKSRRCVLL ::::::::::: NP_001 EPKKSRRCVLL 190 >>NP_001782 (OMIM: 116952,616737) cell division control (191 aa) initn: 1271 init1: 1271 opt: 1271 Z-score: 1490.0 bits: 282.4 E(85289): 2.9e-76 Smith-Waterman score: 1271; 100.0% identity (100.0% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP 130 140 150 160 170 180 190 pF1KE2 EPKKSRRCVLL ::::::::::: NP_001 EPKKSRRCVLL 190 >>NP_426359 (OMIM: 116952,616737) cell division control (191 aa) initn: 1271 init1: 1224 opt: 1224 Z-score: 1435.3 bits: 272.3 E(85289): 3.3e-73 Smith-Waterman score: 1224; 95.3% identity (98.4% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_426 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_426 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::: NP_426 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPP 130 140 150 160 170 180 190 pF1KE2 EPKKSRRCVLL : . .:.: .. NP_426 ETQPKRKCCIF 190 >>NP_008839 (OMIM: 602048) ras-related C3 botulinum toxi (192 aa) initn: 938 init1: 938 opt: 945 Z-score: 1110.3 bits: 212.2 E(85289): 4.2e-55 Smith-Waterman score: 945; 70.8% identity (89.1% similar) in 192 aa overlap (1-191:1-192) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG ::.::::::::::::::::::::::: ::.::.:::::::...::. :.: .:::.:::: NP_008 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR :::::::::::::::::::.:::.:::.:::::. :: ::. ::::.::..::::..::: NP_008 QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP :: .::::: ..: ::: . .:... ::::.:::::::.:::.:::::: :.: :: NP_008 DDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPP 130 140 150 160 170 180 190 pF1KE2 EPKK-SRRCVLL :: .:.:.:: NP_008 PVKKRKRKCLLL 190 >>NP_005043 (OMIM: 602050) ras-related C3 botulinum toxi (192 aa) initn: 948 init1: 920 opt: 929 Z-score: 1091.7 bits: 208.7 E(85289): 4.6e-54 Smith-Waterman score: 929; 69.3% identity (88.5% similar) in 192 aa overlap (1-191:1-192) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG ::.::::::::::::::::::::::: ::.::.:::::::...::. :.: .:::.:::: NP_005 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR :::::::::::::::::::.:::.:::.:::::. :: ::. ::::.::.:::::..::: NP_005 QEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP :: .:::.: .: ::: . .::.. .:::.:::::::.:::.:::::: :.: :: NP_005 DDKDTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPP 130 140 150 160 170 180 190 pF1KE2 EPKK-SRRCVLL :: ...:... NP_005 PVKKPGKKCTVF 190 >>NP_002863 (OMIM: 602049,608203) ras-related C3 botulin (192 aa) initn: 939 init1: 904 opt: 916 Z-score: 1076.5 bits: 205.9 E(85289): 3.2e-53 Smith-Waterman score: 916; 68.8% identity (88.0% similar) in 192 aa overlap (1-191:1-192) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG ::.::::::::::::::::::::::: ::.::.:::::::...::. ..: .:::.:::: NP_002 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR :::::::::::::::::::.:::.:::.:.:::. :: ::. ::::.::..::::..::: NP_002 QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR 70 80 90 100 110 120 130 140 150 160 170 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEP- :: .::::: ..: ::: . ::... .:::.:::::::.:::.:::::: :.: : NP_002 DDKDTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ 130 140 150 160 170 180 180 190 pF1KE2 PEPKKSRRCVLL : ...: : :: NP_002 PTRQQKRACSLL 190 >>NP_036381 (OMIM: 605857) rho-related GTP-binding prote (205 aa) initn: 891 init1: 871 opt: 879 Z-score: 1033.1 bits: 198.0 E(85289): 8.4e-51 Smith-Waterman score: 879; 67.4% identity (86.3% similar) in 190 aa overlap (4-189:10-199) 10 20 30 40 50 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLG .::::::::::::::::.::... :: ::::::::.:::.: .::. : :: NP_036 MAHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KE2 LFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVG :.:::::::::::::::::.:::::.:::::.:.::.::::.::::. .. :..::::.: NP_036 LYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KE2 TQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAIL :::::::::.:. .: :.::: : ..:::... : :::::::::::::.::::::. NP_036 TQIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAII 130 140 150 160 170 180 180 190 pF1KE2 AALEPPEPK-KSR---RCVLL : : : . :.: ::. NP_036 AILTPKKHTVKKRIGSRCINCCLIT 190 200 >>XP_005252973 (OMIM: 179505) PREDICTED: rho-related GTP (191 aa) initn: 837 init1: 837 opt: 837 Z-score: 984.5 bits: 188.9 E(85289): 4.2e-48 Smith-Waterman score: 837; 60.7% identity (85.3% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG ::.:::::::::::::::::: :::: ::.::.:::::::.. . :. .:.:.:::: XP_005 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR ::.::::: ::::::.::..:::..:: :.:::..:: ::. :::: .:.:::::. ::: XP_005 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP .:.:...: .. : ::::. .. ::....::.:.::::: : :.:.:: ::. :.:.: XP_005 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 130 140 150 160 170 180 190 pF1KE2 EPKKSRRCVLL :..: :.:: XP_005 PIKRGRSCILL 190 >>XP_016873208 (OMIM: 179505) PREDICTED: rho-related GTP (191 aa) initn: 837 init1: 837 opt: 837 Z-score: 984.5 bits: 188.9 E(85289): 4.2e-48 Smith-Waterman score: 837; 60.7% identity (85.3% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG ::.:::::::::::::::::: :::: ::.::.:::::::.. . :. .:.:.:::: XP_016 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR ::.::::: ::::::.::..:::..:: :.:::..:: ::. :::: .:.:::::. ::: XP_016 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP .:.:...: .. : ::::. .. ::....::.:.::::: : :.:.:: ::. :.:.: XP_016 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 130 140 150 160 170 180 190 pF1KE2 EPKKSRRCVLL :..: :.:: XP_016 PIKRGRSCILL 190 >>NP_001656 (OMIM: 179505) rho-related GTP-binding prote (191 aa) initn: 837 init1: 837 opt: 837 Z-score: 984.5 bits: 188.9 E(85289): 4.2e-48 Smith-Waterman score: 837; 60.7% identity (85.3% similar) in 191 aa overlap (1-191:1-191) 10 20 30 40 50 60 pF1KE2 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAG ::.:::::::::::::::::: :::: ::.::.:::::::.. . :. .:.:.:::: NP_001 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KE2 QEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLR ::.::::: ::::::.::..:::..:: :.:::..:: ::. :::: .:.:::::. ::: NP_001 QEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KE2 DDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPP .:.:...: .. : ::::. .. ::....::.:.::::: : :.:.:: ::. :.:.: NP_001 AQPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPT 130 140 150 160 170 180 190 pF1KE2 EPKKSRRCVLL :..: :.:: NP_001 PIKRGRSCILL 190 191 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 11 16:57:33 2016 done: Fri Nov 11 16:57:34 2016 Total Scan time: 6.150 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]