FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE2663, 491 aa
  1>>>pF1KE2663     491 - 491 aa - 491 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7899+/-0.000889; mu= 16.1700+/- 0.054
 mean_var=80.4507+/-15.668, 0's: 0 Z-trim(107.4): 16  B-trim: 0 in 0/50
 Lambda= 0.142991
 statistics sampled from 9544 (9554) to 9544 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.293), width:  16
 Scan time:  2.570

The best scores are:                                      opt bits E(32554)
CCDS5140.1 TMEM200A gene_id:114801|Hs108|chr6      ( 491) 3177 665.1 4.7e-191
CCDS45825.1 TMEM200C gene_id:645369|Hs108|chr18    ( 621)  335 78.9 1.7e-14
CCDS30658.1 TMEM200B gene_id:399474|Hs108|chr1     ( 307)  313 74.2 2.3e-13


>>CCDS5140.1 TMEM200A gene_id:114801|Hs108|chr6           (491 aa)
 initn: 3177 init1: 3177 opt: 3177  Z-score: 3543.6  bits: 665.1 E(32554): 4.7e-191
Smith-Waterman score: 3177; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491)

               10        20        30        40        50        60
pF1KE2 MIATGGVITGLAALKRQDSARSQQHVNLSPSPATQEKKPIRRRPRADVVVVRGKIRLYSP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 MIATGGVITGLAALKRQDSARSQQHVNLSPSPATQEKKPIRRRPRADVVVVRGKIRLYSP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE2 SGFFLILGVLISIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVIRNEGGVVVRFFEQHL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 SGFFLILGVLISIIGIAMAVLGYWPQKEHFIDAETTLSTNETQVIRNEGGVVVRFFEQHL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE2 HSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQRQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 HSDKMKMLGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQRQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE2 MNGMYTGLMGETEVKQNGSSCASRLAANTIASFSGFRSSFRMDSSVEEDELMLNEGKSSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 MNGMYTGLMGETEVKQNGSSCASRLAANTIASFSGFRSSFRMDSSVEEDELMLNEGKSSG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE2 HLMPPLLSDSSVSVFGLYPPPSKTTDDKTSGSKKCETKSIVSSSISAFTLPVIKLNNCVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 HLMPPLLSDSSVSVFGLYPPPSKTTDDKTSGSKKCETKSIVSSSISAFTLPVIKLNNCVI
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE2 DEPSIDNITEDADNLKSRSRNLSMDSLVVPLPNTSESFQPVSTVLPRNNSIGESLSSQYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 DEPSIDNITEDADNLKSRSRNLSMDSLVVPLPNTSESFQPVSTVLPRNNSIGESLSSQYK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE2 SSMALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 SSMALGPGAGQLLSPGAARRQFGSNTSLHLLSSHSKSLDLDRGPSTLTVQAEQRKHPSWP
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE2 RLDRNNSKGYMKLENKEDPMDRLLVPQVAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS51 RLDRNNSKGYMKLENKEDPMDRLLVPQVAIKKDFTNKEKLLMISRSHNNLSFEHDEFLSN
              430       440       450       460       470       480

              490 
pF1KE2 NLKRGTSETRF
       :::::::::::
CCDS51 NLKRGTSETRF
              490 

>>CCDS45825.1 TMEM200C gene_id:645369|Hs108|chr18         (621 aa)
 initn: 667 init1: 316 opt: 335  Z-score: 373.5  bits: 78.9 E(32554): 1.7e-14
Smith-Waterman score: 453; 33.2% identity (55.9% similar) in 304 aa overlap (19-272:11-299)

               10        20        30        40        50        60
pF1KE2 MIATGGVITGLAALKRQDSARSQQHVNLSPSPATQEKKPIRRRPRADVVVVRGKIRLYSP
                         :::.:. .   ::   ..:.  ..: . :::::.::..: : 
CCDS45         MIATGGLLRISARKQDPLR-PPSQIPKRKRKAKKRRKNDVVVVKGKLKLCSI
                       10         20        30        40        50 

               70        80                        90           100
pF1KE2 SGFFLILGVLISIIGIAMAVLGYWPQ-----KE-----------HFI----DAETTLSTN
       ::.. . :.:. ..::::::.::::.     .:           : .    .. .. : :
CCDS45 SGLIALCGILVLLVGIAMAVVGYWPKATGTNREGGKQLPPAGSSHRVPTTANSSSSGSKN
              60        70        80        90       100       110 

               110                                   120       130 
pF1KE2 ETQV-IRNEGGV----------------------------VVRFFEQHLHSDKMKMLGPF
       ...   :  :::                              :.:  .:::::.:..::.
CCDS45 RSRSHPRAPGGVNSSSAGAPRSTPPARAASPSSSSTSVGFFFRIFSGYLHSDKLKVFGPL
             120       130       140       150       160       170 

             140       150       160       170       180       190 
pF1KE2 TMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQRQMNGMYTGLMGE
        ::::::.::::::.:::::::.::::..::.::::::.:.:: :.      . ..  . 
CCDS45 IMGIGIFLFICANAVLHENRDKKTKIINLRDLYSTVIDVHSLRAKD------LAAAAAAA
             180       190       200       210             220     

             200       210       220       230       240       250 
pF1KE2 TEVKQNGSSCASRLAANTIASFSGFRSSFRMDSSVEEDELMLNEGKSSGHLMPPLLSDSS
       . .  ..:: :   :      ..:: :       :.   : :. :  .:      .. ..
CCDS45 AAAAASSSSSAPAAAPPGAIPLNGFLS------YVQSRGLELKPGGCGGS--GDAFGAAA
         230       240       250             260         270       

             260        270       280       290       300       310
pF1KE2 VSVFGLYPP-PSKTTDDKTSGSKKCETKSIVSSSISAFTLPVIKLNNCVIDEPSIDNITE
       . . : .:: :.  .  .  :.                                      
CCDS45 MLAKGSWPPHPAAPSGGRPRGAASPPDLASSPRCPREPPSLAEAVYSVYRERSGVAGSRR
       280       290       300       310       320       330       

>>CCDS30658.1 TMEM200B gene_id:399474|Hs108|chr1          (307 aa)
 initn: 431 init1: 165 opt: 313  Z-score: 353.5  bits: 74.2 E(32554): 2.3e-13
Smith-Waterman score: 313; 41.2% identity (70.6% similar) in 119 aa overlap (41-156:30-145)

               20        30        40          50        60        
pF1KE2 LAALKRQDSARSQQHVNLSPSPATQEKKPIRRRPRA--DVVVVRGKIRLYSPSGFFLILG
                                     :::::.  . . ::...:: :::: :  ::
CCDS30  MTAGSPEECGEVRRSPEGRVSRLGRRLGRRRRPRSPPEPLRVRARLRLRSPSGAFAALG
                10        20        30        40        50         

       70        80        90        100       110       120       
pF1KE2 VLISIIGIAMAVLGYWPQKEHFIDAETT-LSTNETQVIRNEGGVVVRFFEQHLHSDKMKM
       .:. ..:...:: ::::..     ....  :. . . .: ::    :    :   .....
CCDS30 ALVVLVGMGIAVAGYWPHRAGAPGSRAANASSPQMSELRREGRGGGRAHGPH---ERLRL
      60        70        80        90       100       110         

       130       140       150       160       170       180       
pF1KE2 LGPFTMGIGIFIFICANAILHENRDKETKIIHMRDIYSTVIDIHTLRIKEQRQMNGMYTG
       :::  ::.:.:.:::::..:.:::: ::.                               
CCDS30 LGPVIMGVGLFVFICANTLLYENRDLETRRLRQGVLRAQALRPPDGPGWDCALLPSPGPR
        120       130       140       150       160       170      




491 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Jan 20 09:30:13 2017 done: Fri Jan 20 09:30:13 2017
 Total Scan time:  2.570 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]